Genes with mutations linked to hereditary cancer risk
Inherited mutations have been linked to many different types of mutations. Some types of cancer are more likely to be hereditary. Below is a list of common cancers, and the most common genes that have been linked to increased risk for each.
|Breast cancer in women|
|Breast cancer in men|
|Fallopian tube, ovarian, primary peritoneal cancer|
*BRCA1 mutations have been linked to a very rare but aggressive type of cancer known as serous endometrial cancer. The lifetime risk for endometrial cancer is not increased in women with BRCA1 mutations, but there is a small increase in risk for this rare subtype.
**More research is needed to confirm a link between this cancer type and an inherited mutation in this gene.
*** Most ovarian tumors in people with this mutation are benign.