Genes with mutations linked to risk
Inherited mutations have been linked to many different types of mutations. Some types of cancer are more likely to be hereditary. Below is a list of common cancers, and the most common genes that have been linked to increased risk for each.
|Breast cancer in women|
|Breast cancer in men|
APC, , , , , , , , , , MUTYH
|, ovarian, primary peritoneal cancer|
APC, , , , , , , **
, , , CDKN2A, **, , **, **, , ,
*BRCA1 mutations have been linked to a very rare but aggressive type of cancer known as serous endometrial cancer. The lifetime risk for endometrial cancer is not increased in women with mutations, but there is a small increase in risk for this rare subtype.
**More research is needed to confirm a link between this cancer type and an inherited mutation in this gene.