Genetic testing for inherited mutations
Genetic testing for an inherited mutation (also called "germline genetic testing") looks at DNA found in blood or saliva samples to find mutations that can cause diseases such as cancer.
Genetic testing can help people understand their risk for cancer, help them make medical decisions, and take steps to lower their cancer risk or detect cancer early. For people already diagnosed with cancer, genetic testing can help people make medical decisions about how to best treat their cancer.
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The following clinical trials include genetic counseling and testing:
- NCT03762590: GENetic Education Risk Assessment and TEsting Study (GENERATE) is for untested relatives of people diagnosed with pancreatic cancer who have an inherited mutation
- A Study in Hereditary Breast and Ovarian Cancer Families to Provide Men With Up-To-Date Information About the Personal Importance of Genetic Testing (GEM) is for men from families in which a BRCA1/2 gene mutation has been identified.
- NCT02620852: WISDOM Study: Women Informed to Screen Depending on Measures of Risk offers women age 40-74 the opportunity to undergo risk assessment and genetic testing in order to determine the best breast screening options based on their situation.
- PHACT Study: Population Health and Cancer Testing offers genetic testing to women and men of Ashkenazi (Eastern European) Jewish ancestry, age 21 or older.
Visit our Research Search and Enroll Tool to find other studies that include genetic counseling and/or testing as part of the study.