Cancer Risk
Read about different genes that are linked to hereditary cancer, their associated risks and guidelines for screening, preventing and treating cancers in people with inherited mutations in these genes.Stay up to date on research and information
Sign Up for FORCE NewslettersCancer Risks Associated with Inherited Mutations
If you have tested positive for a mutation, we recommend you speak with a genetics expert who can look at your personal and family history of cancer and can help you decide on a plan for managing your cancer risk. Note that when we use "men" and "women" we are referring to the sex you were assigned at birth.
, ovarian and primary peritoneal cancer risks
- People with a mutation have a 5-15% lifetime risk of , ovarian or primary peritoneal cancer. These three cancers are related and are often referred to together as ovarian cancer.
Other cancer risks for people with a mutation
There is not yet enough research to conclude that a mutation is associated with an increased risk of other adult-onset cancers. Research on the risk for cancer in people with mutations is ongoing.
It is important to note that cancer risks are estimates over the course of a person's lifetime. Your lifetime risk and risk over the next five years will vary depending on:
- current age
- sex assigned at birth
- specific mutation
- personal and family health history
- diet, exercise, lifestyle and other factors
NCT02665195: Registry Of MultiPlex Testing (PROMPT). PROMPT is an online research registry. The goal of PROMPT is to help researchers to better understand the risks that are linked to mutations in less well-studied genes. People with inherited mutations can enroll in PROMPT to help researchers learn more about cancer risks.
FORCE offers many peer support programs for people with inherited mutations.
- Our Message Boards allow people to connect with others who share their situation. Once registered, you can post on the Diagnosed With Cancer board to connect with other people who have been diagnosed.
- Our Peer Navigation Program will match you with a volunteer who shares your mutation and situation.
- Our moderated, private Facebook group allows you to connect with other community members 24/7.
- Check out our virtual and in-person support meeting calendar.
- Join one of our Zoom community group meetings.