The only way to improve cancer detection, prevention, and treatment is through research. People participating in research contribute to medical knowledge and have opportunity to receive cutting-edge care.
Click on the “Search Now” button to search for research studies enrolling people like you. Need help getting started? Click on “Tips for Searching Studies” to find resources and assistance to help you find studies.
Survey about Endometrial Cancer Risk and Risk-Reducing Surgery for Women with a BRCA1/2 Mutation or Mutation in the Family
Surveys, Registries, Interviews
Women with a BRCA mutation OR from a family with a BRCA mutation
EnergyPoints: A Mobile App Guiding Use of Acupressure for Cancer-related Fatigue and Sleep Disturbances
Quality of Life
Anyone diagnosed with cancer experiencing fatigue
PARP inhibitor (niraparib) in patients with inherited or tumor PALB2 mutations in advanced solid tumors (PAVO)
Clinicaltrials.gov identifier:
NCT05169437
Treatment
Any advanced or metastatic solid tumor except ovarian or prostate
TALAPRO-3: A Clinical Trial in Men with Metastatic Castration-Sensitive Prostate Cancer (mCSPC) and DNA Damage Repair (DDR) Gene Alteration
Clinicaltrials.gov identifier:
NCT04821622
Treatment
Metastatic castration-sensitive prostate cancer
Prostate Cancer Genetic Risk Evaluation and Screening Study (PROGRESS)
Clinicaltrials.gov identifier:
NCT05129605
Prevention
People at high risk for prostate cancer due to an inherited mutation
BRCA 1 and 2: Interviews on Genetic Testing and Individual Experiences
Surveys, Registries, Interviews
People with or without cancer who have had or are considering BRCA testing
UCLA Research Study: Zoom Interviews to Learn from Asian Americans Living with Metastatic Cancer
Surveys, Registries, Interviews
Asian Americans with metastatic cancer of any type
A Study of Melphalan, BCNU, Vitamin B12b, Vitamin C, and Stem Cell Infusion in People with Advanced Pancreatic Cancer and BRCA Mutations
Clinicaltrials.gov identifier:
NCT04150042
Treatment
Advanced pancreatic cancer in people with a BRCA1 or BRCA2 mutation
Interview Study: Exploring Gender Diverse Experiences of Hereditary Cancer Risk
Surveys, Registries, Interviews
People with elevated cancer risk who identify as trans* or nonbinary
Androgen Suppression With Abiraterone, Leuprolide, PARP Inhibitor and Stereotactic Radiotherapy in Prostate Cancer (ASCLEPIuS)
Clinicaltrials.gov identifier:
NCT04194554
Treatment
Newly diagnosed prostate cancer grade group 3-5
Combination ATR inhibitor and PARP Inhibitor in Recurrent Ovarian Cancer (CAPRI)
Clinicaltrials.gov identifier:
NCT03462342
Treatment
Recurrent ovarian cancer
Treating Early-Stage BRCA, or PALB2-Associated Breast Cancer with a PARP Inhibitor (Niraparib) and Immunotherapy (Dostarlimab)
Clinicaltrials.gov identifier:
NCT04584255
Treatment
Early-stage breast cancer & a BRCA1, BRCA2 or PALB2 mutation
Investigational PARP Inhibitor AZD5305 Alone or in Combination With Other Anti-cancer Agents in Patients With Advanced Solid Tumors (PETRA)
Clinicaltrials.gov identifier:
NCT04644068
Treatment
Advanced ovarian, breast, prostate or pancreatic cancer
Targeted Therapy RP-3500 Alone or in Combination with Talazoparib or Gemcitabine in Advanced Solid Tumors with DNA Damage Repair Mutations (TRESR Study)
Clinicaltrials.gov identifier:
NCT04497116
Treatment
Advanced solid tumors
Screening for Cancer DNA in the Blood after Treatment for Early-Stage TNBC and/or a BRCA Mutation; Followed by Study Comparing Niraparib with Placebo for People with Cancer DNA found in their Blood (ZEST)
Clinicaltrials.gov identifier:
NCT04915755
Treatment
Early-stage TNBC or early-stage breast cancer with a BRCA mutation
ATR Inhibitor Plus Niraparib Study in Advanced Solid Tumors and Ovarian Cancer
Clinicaltrials.gov identifier:
NCT04267939
Treatment
Advanced ovarian cancer or other solid tumors
Survey: Making Decisions about Genetic Testing
Surveys, Registries, Interviews
Survey for adults who have had genetic testing for inherited cancer risk through a doctor
A Survey on Health Behaviors for Women with BRCA1/2 Mutations
Surveys, Registries, Interviews
Survey for women with a BRCA1 or BRCA2 mutation
Adding Pembrolizumab to Olaparib to Treat Pancreatic Cancer in People with an Inherited BRCA Mutation
Clinicaltrials.gov identifier:
NCT04548752
Treatment
Metastatic pancreatic cancer and a BRCA1 or BRCA2 mutation
Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in People With MSI-High or dMMR Stage IV Colorectal Cancer
Clinicaltrials.gov identifier:
NCT04895722
Treatment
Stage 4 colorectal cancer
Survey: Medical Records to Save After a Cancer Diagnosis
Surveys, Registries, Interviews
Adults with cancer
Studying Crowdfunding for Cancer
Surveys, Registries, Interviews
Cancer survivors who have used crowdfunding to help cover cancer-related costs
Tools To Be Fit: Tools to Improve Nutrition and Physical Activity for Colorectal Cancer Survivors
Clinicaltrials.gov identifier:
NCT05056077
Quality of Life
Nonmetastatic colon or rectal cancer
A Study of the Investigational Targeted Therapy ART4215 to Treat Advanced or Metastatic Solid Tumors
Clinicaltrials.gov identifier:
NCT04991480
Treatment
Advanced solid tumors
Investigating BRCA Previvors’ Utilization of Social Media for Health Decision Making and Social Support
Surveys, Registries, Interviews
Women with a BRCA1 or BRCA2 mutation who have never had cancer
Survey: How Willing are You to Participate in Different Types of Clinical Trials for the Prevention of Breast Cancer?
Surveys, Registries, Interviews
Retifanlimab Alone or with Other Agents for Advanced Endometrial Cancer that Progressed with Platinum
Clinicaltrials.gov identifier:
NCT04463771
Treatment
Advanced endometrial cancer
Testing a Vaccine for Cancer Prevention in People with a BRCA1 or BRCA2 Mutation
Clinicaltrials.gov identifier:
NCT04367675
Prevention
People with a BRCA1 or BRCA2 mutation
A National Survey to Share the Voices of Ovarian Cancer Caregivers
Surveys, Registries, Interviews
Caregivers to people with ovarian cancer
Niraparib Before Surgery in Treating Patients With High Risk Localized Prostate Cancer and DNA Damage Response Defects
Clinicaltrials.gov identifier:
NCT04030559
Treatment
High-risk localized prostate cancer
Treatment with ATR Inhibitor for Advanced or Metastatic Solid Tumors
Clinicaltrials.gov identifier:
NCT04657068
Treatment
Advanced solid tumors
Treating Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer with Chemotherapy and Rucaparib
Clinicaltrials.gov identifier:
NCT03337087
Treatment
Metastatic colorectal, pancreatic, gastroesophageal or biliary tract cancer
Dostarlimab Plus Carboplatin-paclitaxel Versus Placebo Plus Carboplatin-paclitaxel for Recurrent or Primary Advanced Endometrial Cancer (RUBY)
Clinicaltrials.gov identifier:
NCT03981796
Treatment
Metastatic endometrial cancer
CYH33 in Combination With Olaparib in Patients With Advanced Solid Tumors and DNA Damage Repair Mutations
Clinicaltrials.gov identifier:
NCT04586335
Treatment
Advanced solid tumors
A National Survey to Share the Voice and Treatment Preferences of Ovarian Cancer Patients
Surveys, Registries, Interviews
Ovarian cancer
Nivolumab and Relatlimab in Advanced MSI-H Cancers Resistant to Prior PD-L1 Inhibitor
Clinicaltrials.gov identifier:
NCT03607890
Treatment
Solid tumors that are MSI-High and resistant to prior immunotherapy
Atorvastatin ± Aspirin for Colorectal Cancer Prevention for People with Lynch Syndrome
Clinicaltrials.gov identifier:
NCT04379999
Prevention
Olaparib, Palbociclib and Fulvestrant for BRCA-Associated, ER/PR-Positive, Her2-Negative Metastatic Breast Cancer
Clinicaltrials.gov identifier:
NCT03685331
Treatment
A Study to Compare Two Surgical Procedures in Women with BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer (SOROCk)
Clinicaltrials.gov identifier:
NCT04251052
Prevention
Treating Metastatic Pancreatic Cancer with an Inherited or Tumor BRCA1/2 or PALB2 Mutation with Niraparib and Dostarlimab
Clinicaltrials.gov identifier:
NCT04493060
Treatment
AMPLIFY: a new online weight loss study specifically for cancer survivors!
Clinicaltrials.gov identifier:
NCT04000880
Quality of Life
Developing a Test for the Detection of Ovarian Cancer
Clinicaltrials.gov identifier:
NCT04794322
Prevention
PROMISE Registry: A Prostate Cancer Registry of Outcomes and Germline Mutations for Improved Survival and Treatment Effectiveness
Clinicaltrials.gov identifier:
NCT04995198
Surveys, Registries, Interviews
Treating Advanced Solid Tumors in People with Inherited PTEN Mutations Using the Investigational Drug TAS-117
Clinicaltrials.gov identifier:
NCT04770246
Treatment
People with advanced cancer and an inherited PTEN mutation
Chemotherapy, Bevacizumab, and/or Atezolizumab for dMMR / MSI-H Metastatic Colorectal Cancer (COMMIT Study)
Clinicaltrials.gov identifier:
NCT02997228
Treatment
TALAVE: Talazoparib Followed by Combination of Talazoparib and Avelumab in Advanced Breast Cancer
Clinicaltrials.gov identifier:
NCT03964532
Treatment
Screening for Pancreatic Cancer in Patients with an Inherited BRCA1, BRCA2, PALB2 or ATM Mutation
Clinicaltrials.gov identifier:
NCT02478892
Prevention
Omega 3 Fatty Acids in Colorectal Cancer (CRC) Prevention in Patients With Lynch Syndrome (COLYNE)
Clinicaltrials.gov identifier:
NCT03831698
Prevention
Olaparib or Placebo in Patients with Surgically Removed Pancreatic Cancer who have a BRCA1, BRCA2 or PALB2 Mutation
Clinicaltrials.gov identifier:
NCT04858334
Treatment
Phase 1 Study of Oral Drug PMD-026 in People With Metastatic Breast Cancer and Metastatic Triple Negative Breast Cancer
Clinicaltrials.gov identifier:
NCT04115306
Treatment
Addition of Pembrolizumab to Radiation Treatment for Newly Diagnosed Early Stage MSI-High Endometrial Cancer
Clinicaltrials.gov identifier:
NCT04214067
Treatment
Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations
Clinicaltrials.gov identifier:
NCT04042831
Treatment
Nivolumab, Nivolumab Plus Ipilimumab, or Chemotherapy for Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (CheckMate 8HW)
Clinicaltrials.gov identifier:
NCT04008030
Treatment
People with metastatic colorectal cancer that is MSI-High
Pembrolizumab and Olaparib for Metastatic Pancreatic Cancer with Homologous Recombination Deficiency or Exceptional Response to Platinum Chemotherapy
Clinicaltrials.gov identifier:
NCT04666740
Treatment
Mobile Mindfulness Meditation Intervention to Improve Neuropathy in Cancer Survivors
Clinicaltrials.gov identifier:
NCT03581357
Quality of Life
Parenting Adolescent-Aged Children While Managing a Parental Cancer Diagnosis – Share Your Story
Surveys, Registries, Interviews
Mobile Mindfulness Meditation Intervention for Cancer Survivors
Clinicaltrials.gov identifier:
NCT03581357
Quality of Life
A Survey on Options for Managing Cancer Risk Among Women with a BRCA1 or BRCA2 Mutation
Surveys, Registries, Interviews
Olaparib Expanded - Treating Metastatic Breast Cancer in People without gBRCA Mutations
Clinicaltrials.gov identifier:
NCT03344965
Treatment
The Risk Factor Analysis of Hereditary Breast and Ovarian Cancer In Women with BRCA1, BRCA2 or PALB2 Mutations
Surveys, Registries, Interviews
PARP Inhibitor for Metastatic Prostate Cancer With DNA Repair Defects
Clinicaltrials.gov identifier:
NCT03012321
Treatment
Prostate Cancer Genetic Risk, Experience, and Support Study (PROGRESS)
Surveys, Registries, Interviews
Diagnosis of Breast Cancer in Young Women - Share Your Story
Surveys, Registries, Interviews
Talazoparib for people with metastatic breast cancer who have acquired (somatic) BRCA mutations
Clinicaltrials.gov identifier:
NCT03990896
Treatment
A Study of Nivolumab in Selected Uterine Cancer Patients
Clinicaltrials.gov identifier:
NCT03241745
Treatment
PARP Inhibitor Alone or Plus Immunotherapy for Advanced BRCA-Associated Breast Cancer
Clinicaltrials.gov identifier:
NCT02849496
Treatment
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair
Clinicaltrials.gov identifier:
NCT02912559
Treatment
Genetic Testing for Men with Metastatic Prostate Cancer (GENTleMEN Study)
Clinicaltrials.gov identifier:
NCT03503097
Treatment
Decision Navigation for Advanced Prostate Cancer Treatment Options Using mHealth
Clinicaltrials.gov identifier:
NCT03327103
Quality of Life
Pancreatic Cancer Screening Study for High Risk People
Clinicaltrials.gov identifier:
NCT03250078
Prevention
Denosumab and Mammographic Density in Premenopausal Women With Dense Breasts (TRIDENT)
Clinicaltrials.gov identifier:
NCT04067726
Prevention
Study of Safety and Effectiveness of Motiva® Breast Implants
Clinicaltrials.gov identifier:
NCT03579901
Quality of Life
Study for People with Unexpected Genetic Results
Clinicaltrials.gov identifier:
NCT02595957
Prevention
A Study to Evaluate Rucaparib in Patients with Solid Tumors and with Deleterious Mutations in HRR Genes
Clinicaltrials.gov identifier:
NCT04171700
Treatment
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Talking to Employers and Medical Staff About Breast Cancer Treatment and Your Job
Clinicaltrials.gov identifier:
NCT03572374
Quality of Life
INTERVAL: INTense Exercise foR surVivAL in Men With Metastatic Prostate Cancer
Clinicaltrials.gov identifier:
NCT02730338
Quality of Life
RADCOMP: A Study at the Heart of Breast Cancer Treatment
Clinicaltrials.gov identifier:
NCT02603341
Treatment
Identification and Analysis of Families With Genetic Susceptibility To Cancer Registry
Surveys, Registries, Interviews
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