Get notified of page updates
BARD1: Cancer Risk
People with an inherited mutation in the BARD1 gene have an increased risk for breast cancer. Learn more how BARD1 mutations affect breast cancer risk.

Stay up to date on research and information

Sign Up for FORCE Newsletters
Glossary on
off

Cancer Risk Associated with Inherited Mutations

If you have tested positive for a  mutation, we recommend that you speak with a genetics expert who can look at your personal and family history of cancer and can help you choose the best plan for managing your cancer risk. Note that when we use "men" and "women" we are referring to the sex you were assigned at birth.

  • Women with a mutation have an increased risk of breast cancer. The estimated lifetime risk of breast cancer is as high as 30 percent.  
  • Currently, there is not enough evidence to show a link between mutations and an increased risk of other cancers.

It is important to note that cancer risks are estimates over the course of a person's lifetime. Your lifetime risk and risk over the next five years will vary depending on:

  • current age
  • sex assigned at birth
  • specific mutation
  • personal and family health history
  • diet, exercise, lifestyle and other factors

Research on the risk for cancer in people with mutations is ongoing. 

Risk Graph

Graph of lifetime risk for breast cancer in a woman with a BARD1 mutation

Last updated June 21, 2024