BARD1 Mutations: Cancer Risk
Cancer Risk Associated with Inherited BARD1 Mutations
If you have tested positive for a mutation, we recommend that you speak with a genetics expert who can look at your personal and family history of cancer and can help you choose the best plan for managing your cancer risk.
Experts at the National Comprehensive Cancer Network (NCCN) created guidelines which estimate the cancer risks for people with mutations. These cancer risk estimates are updated based on the latest research. According to the 2027 guidelines:
- Women with a mutation have an increased risk of breast cancer. The estimated lifetime risk of breast cancer is 17%- 30%.
- Currently, there is not enough evidence to show a link between mutations and an increased risk of other cancers.
It is important to note that cancer risks are estimates over the course of a person's lifetime. Your lifetime risk and risk over the next five years may vary depending on your:
- current age.
- sex assigned at birth.
- specific location and type of mutation on the gene.
- personal and family health history.
- diet, exercise, lifestyle and other factors.
Research on the risk for cancer in people with mutations is ongoing.
Get notified when updated information becomes available.
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