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Read about different genes that are linked to hereditary cancer, their associated risks and guidelines for screening, preventing and treating cancers in people with inherited mutations in these genes.
Read about different genes that are linked to hereditary cancer, their associated risks and guidelines for screening, preventing and treating cancers in people with inherited mutations in these genes.
Cancer risk associated with inherited mutations
If you have tested positive for a mutation, we recommend that you speak with a genetics expert who can look at your personal and family history of cancer and can help you choose the best plan for managing your cancer risk.
- Women with a mutation have an increased risk of breast cancer, especially . The estimated lifetime risk of breast cancer is as high as 40 percent.
- Currently, there is not enough evidence to show a link between mutations and an increased risk of other cancers.
Research on the risk for cancer in people with mutations is ongoing.
clinical-trials
NCT02665195: Registry Of MultiPlex Testing (PROMPT). PROMPT is an online research registry. The goal of PROMPT is to help researchers to better understand the risks that are linked to mutations in less well-studied genes. People with inherited mutations can enroll in PROMPT to help researchers learn more about cancer risks.
updated: 02/05/2022
Last updated March 12, 2022