Hereditary Cancer and Genetic Testing

Cancer treatment for people with inherited CDKN2A mutations

Currently there are no cancer treatments approved specifically for people with a CDKN2A mutation, nor guidelines for treating cancer written specifically for people with a CDKN2A mutation. Consider participating in a clinical trial to help experts learn which treatments work best for someone with an inherited CDKN2A mutation. 

To learn more about standard of care treatment options for specific types of cancer, visit our section on Cancer Treatment by Cancer Type


If you are a person with a CDKN2A mutation, you can find peer support through the following resources:

Other organizations that provide support for people diagnosed with pancreatic cancer include:

  • PanCAN is a nonprofit organization for people diagnosed with pancreatic cancer. 
  • Let's Win PC is a nonprofit organization that enables doctors, scientists, and patients to share fast-breaking information on potentially life-saving pancreatic cancer treatments and clinical trials.

The majority of public and private health insurance plans are required to cover cancer diagnosis and treatment; copays, coinsurance and deductibles often apply. Patient costs and coverage for specific doctors, facilities or treatments may vary based on your health plan. If your insurance company denies your claim, your health care provider can help you write an appeal letter, or you can use one of our sample appeal letters. Visit our section on Insurance and Paying for Care: Treatment for more information.


The following clinical trials may be enrolling people with an CDKN2A inherited mutation who have been diagnosed with cancer.

Last updated July 28, 2020