Cancer risk associated with an inherited RAD51C mutation
If you have tested positive for a RAD51C mutation, we recommend consulting with a genetics expert who can assess your personal and family history of cancer and can help you determine the best risk management plan.
Risk for women
- Women with a RAD51C mutation have about a 10 percent lifetime risk for ovarian cancer.
- Women with a RAD51C mutation have about a 15-40 percent lifetime risk for breast cancer with a tendency for triple-negative breast cancer.
Risk for men
- Currently there is no evidence of increased cancer risk in men with a RAD51C mutation.