Cancer treatment for people with inherited CDK4 mutations
Currently there are no cancer treatments approved specifically for people with a CDK4 mutation, nor guidelines for treating cancer written specifically for people with a CDK4 mutation. Consider participating in a clinical trial to help experts learn which treatments work best for someone with an inherited CDK4 mutation.
To learn more about standard of care treatment options for specific types of cancer, visit our section on Cancer Treatment by Cancer Type.
If you are a person with a CDKN2A mutation, you can find peer support through the following resources:
- Register for the FORCE Message Boards to connect with others who share your situation. Once you register, you can post on the Share Your Mutation board to connect with other people who carry a CDK4 mutation and the Diagnosed With Cancer board to connect with other people who have been diagnosed.
- FORCE's Peer Navigation Program will match you with a volunteer who shares your mutation and situation and provide you with a free resource guide.
- Contact the FORCE impact leaders in your area to link to local support groups and other resources.
- Attend a virtual support meeting in your area.
- Read the stories from members of our community.
Other organizations that provide support for people diagnosed with melanoma include:
- AIM at Melanoma is a nonprofit organization that has online support and a list of in-person support groups by region.
The following clinical trials may be enrolling people with a CDK4 inherited mutation who have been diagnosed with cancer.
NCT03207347: A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001). This study will investigate the use of niraparib in patients with tumors known to have mutations in select DNA damage response pathway genes including CDKN2A.