Hereditary Cancer and Genetic Testing

Medical decisions for people with an inherited TP53 mutation who have been diagnosed with cancer

Currently there are no cancer treatments approved specifically for people with a TP53 mutation. However, guidelines do recommend that people with an inherited TP53 mutation minimize their radiation exposure, which increases the risk of a new cancer diagnosis. This includes avoiding radiation therapy for cancer treatment whenever possible. To learn more about standard of care treatment options for specific types of cancer, visit our section on Cancer Treatment by Cancer Type


If you are a person with an inherited TP53 mutation, you can find peer support through the following resources:


The majority of public and private health insurance plans are required to cover cancer diagnosis and treatment; copays, coinsurance and deductibles often apply. Patient costs and coverage for specific doctors, facilities or treatments may vary based on your health plan. If your insurance company denies your claim, your health care provider can help you write an appeal letter, or you can use one of our sample appeal letters. Visit our section on Insurance and Paying for Care: Treatment for more information.

Last updated September 24, 2021