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Cancer Risk
Read about different genes that are linked to hereditary cancer, their associated risks and guidelines for screening, preventing and treating cancers in people with inherited mutations in these genes.
Glossary on

Cancer Risk Associated with Inherited Mutations

If you have tested positive for an inherited mutation, we recommend consulting with a genetics expert who can look at your personal and family history of cancer and can help you decide on a risk-management plan. 

Note that when we use the term "men" we are referring to the sex you were assigned at birth.

Risks for men with a mutation

mutations increase the risk for  cancer. This risk may be associated with a younger age of diagnosis. More research is needed to better measure the lifetime cancer risk associated with a mutation in this gene. 

Other cancer risks for people with a mutation

There is not yet enough research to conclude that a mutation increases the risk of other cancers. Research on the risk for cancer in people with mutations is ongoing. 

Last updated December 31, 2023

Get Support
Get Support

The following organizations offer peer support services for people with or at high risk for cancer:

updated: 03/08/2023

Get Support
Get Support

FORCE offers many peer support programs for people with inherited mutations. 

updated: 08/06/2022

Open Clinical Trials
Open Clinical Trials

The following are studies looking at ways to screen for cancer in people at high risk: 

updated: 03/12/2023

Open Clinical Trials
Open Clinical Trials

NCT02665195: Registry Of MultiPlex Testing (PROMPT). PROMPT is an online research registry. The goal of PROMPT is to help researchers to better understand the risks that are linked to mutations in less well-studied genes. People with inherited mutations can enroll in PROMPT to help researchers learn more about cancer risks. 

updated: 05/29/2023