FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you.
XRAY is a reliable source of hereditary cancer research-related news and information.
Learn more about the XRAY program
In portal: Breast Cancer
Update : FDA reports on new cancers linked to breast implants
Most relevant for: People with breast implants
New cancers have been found in women with both textured and smooth implants that are filled with either saline or silicone. These cancers are extremely rare. The FDA has reported cases of a type of skin cancer and blood cancers in the scar tissue that forms around breast implants. The newly reported lymphomas are different from the previously reported breast implant-associated anaplastic large cell lymphoma (BIA-ALCL). (Posted 9/27/22). Este artículo está disponible en español.
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Relevance: Medium-High
Strength of Science: Medium-High
Study : Expanding Medicaid reduced racial disparities among people with metastatic breast cancer
Relevance: Medium-High
Strength of Science: Medium-High
Most relevant for: People diagnosed with de novo stage 4 breast cancer and people who live in states that have not expanded Medicaid.
The Affordable Care Act allowed more people to access insurance through Medicaid. This study found the expansion of care improved survival and decreased mortality among people of color with de novo stage 4 (stage 4 at the time of initial diagnosis) breast cancer. (Posted 9/13/2022). Este artículo está disponible en español.
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Relevance: Medium-High
Strength of Science: High
Research Timeline: Post Approval
Study : Physical activity may decrease fatigue associated with cancer treatment
Relevance: Medium-High
Strength of Science: High
Research Timeline: Post Approval
Most relevant for: Cancer patients who are experiencing fatigue related to cancer or its treatment.
Many cancer survivors experience fatigue during and after they complete treatment. This study looked at the effect of home-based physical activity on fatigue in cancer survivors. It also looked at whether frequent counseling encouraged people to start and continue their exercise routines. (Posted 8/1/22). Este artículo está disponible en español.
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Relevance: High
Strength of Science: High
Research Timeline: Post Approval
Study : A win for some patients with HER2-negative metastatic breast cancer
Relevance: High
Strength of Science: High
Research Timeline: Post Approval
Most relevant for: People with HER2-low metastatic breast cancer
A drug used to treat HER2-positive breast cancer improved survival in people with metastatic breast cancers that were previously considered HER2-negative. These results change practice guidelines for metastatic breast cancer and reclassify HER2 tumor marker status as “HER2-low” to guide treatment. (Posted 7/18/22)
Update: On 08/05/2022 the FDA approved Enhertu to treat people with metastatic, HER2-low breast cancer who have received prior chemotherapy in the metastatic setting or who developed disease recurrence during or within six months of completing chemotherapy. Enhertu is also approved for treatment of people with metastatic HER2-positive breast cancer who progressed after prior anti-HER2 treatment. Este artículo está disponible en español.
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Relevance: High
Strength of Science: Medium-High
Research Timeline: Post Approval
Study : The hidden financial burden of treating cancer care symptoms
Relevance: High
Strength of Science: Medium-High
Research Timeline: Post Approval
Most relevant for: People who are experiencing side effects due to cancer treatment or cancer.
Drugs commonly used to treat symptoms of cancer and cancer treatment side effects can cost thousands of dollars out of pocket for patients, depending on what drugs are used. (Posted 6/29/2022). Este artículo está disponible en español.
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Relevance: Medium
Strength of Science: Medium
Research Timeline: Post Approval
Study : Do artificial sweeteners increase the risk of cancer?
Relevance: Medium
Strength of Science: Medium
Research Timeline: Post Approval
Most relevant for: People who consume artificial sweeteners
A large study of adults in France suggests that artificial sweeteners may increase the risk of certain cancers. (posted 6/21/2022). Este artículo está disponible en español.
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Article : Breast cancer risk for transgender men with inherited mutations
Most relevant for: Transgender men with an inherited mutation
There is little information related to the risks and treatment options for transgender men and nonbinary people who are at high-risk for breast cancer due to an inherited BRCA1 or BRCA2 mutation. We review an expert viewpoint on the implications of a BRCA mutation for transgender men undergoing breast removal as part of their gender-affirming care plan. (posted 5/19/22)
Este artículo está disponible en español.
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Relevance: Medium
Strength of Science: Medium-High
Research Timeline: Post Approval
Study : Increasing melatonin use raises concerns
Relevance: Medium
Strength of Science: Medium-High
Research Timeline: Post Approval
Most relevant for: people who take or consider taking melatonin to help with sleep.
Adult use of melatonin as a sleep aid has increased even though its benefits and risks are not well understood. This study looked at trends in melatonin use over the last 19 years. (Posted 4/14/2022)
Este artículo está disponible en español.
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Relevance: Medium-High
Strength of Science: Medium-High
Research Timeline: Post Approval
Study : New tool to predict breast cancer risk for Black women
Relevance: Medium-High
Strength of Science: Medium-High
Research Timeline: Post Approval
Most relevant for: Black women in the U.S.
An important part of making decisions about breast cancer screening and prevention is knowing your breast cancer risk. Specific tools are used to identify people who would benefit from early and/or additional screening and chemoprevention or those who would most benefit from genetic counseling and testing. Because these tools were developed using data mostly from white women, they are unable to predict cancer risk as well for Black women. To begin to address these gaps, researchers developed a new tool specifically designed to predict breast cancer risk for Black women. This tool has been shown to work well, especially for younger Black women. (posted 3/22/2022) Este artículo está disponible en español.
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Relevance: High
Strength of Science: Medium-High
Research Timeline: Post Approval
Study : The chance of a second breast cancer is higher among some Hawai'ian women
Relevance: High
Strength of Science: Medium-High
Research Timeline: Post Approval
Most relevant for: women of Hawai’ian, Filipino or Asian American ancestry.
Women diagnosed with ductal carcinoma in situ (DCIS), an early form of breast cancer, are more likely to have a second breast cancer diagnosis if they are of Native Hawai'ian, Filipino or Japanese ancestry than women of other racial or ethnic groups. (posted 3/15/22)
Este artículo está disponible en español.
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