FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you.
XRAY is a reliable source of hereditary cancer research-related news and information.
Learn more about the XRAY program
All XRAYs
Relevance: High
Strength of Science: High
Research Timeline: Post Approval
Study : Immunotherapy improves outcomes of advanced endometrial cancer
Most relevant for: People with advanced endometrial cancer
Standard treatment for advanced endometrial cancer may soon change. A study found that people with advanced or recurrent endometrial cancer who received immunotherapy with chemotherapy had better outcomes than those who had chemotherapy alone. (Posted 12/4/23)
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Relevance: Medium
Article : Breast cancer risk for transgender women with inherited mutations
Most relevant for: Transgender women have an inherited mutations who are considering or have had gender affirming care.
There has been little research on breast cancer risk for transgender women who are at high risk for breast cancer due to an inherited mutation. This review summarizes what we know. (Posted 11/29/23)
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Relevance: High
Quality of Writing: High
Article : Signs of endometrial cancer: Six survivor stories
Most relevant for: Women who want to learn more about the signs of or are at risk for endometrial cancer.
This article shares the experiences of six women diagnosed with endometrial cancer. It highlights the most common signs of endometrial cancer. (Posted 11/16/23)
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Update : New drug combination approved for treatment of BRCA-mutated metastatic prostate cancer
Most relevant for: People with metastatic castration resistant prostate cancer with a mutation in BRCA1 or BRCA2
The FDA approved Akeega (niraparib and abiraterone) plus prednisone for the treatment of BRCA-mutated, metastatic castration-resistant prostate cancer (mCRPC). Akeega can be used as an early or later treatment. (Posted 11/9/23)
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Relevance: Medium-High
Strength of Science: Medium-High
Research Timeline: Post Approval
Study : Pausing hormone therapy to pursue pregnancy does not increase the short-term risk of early-stage cancer recurrence
Most relevant for: Women with breast cancer who are considering pregnancy
Women who paused hormone therapy treatment of early-stage hormone receptor-positive (HR-positive) breast cancer to attempt to get pregnant had no increase in short-term recurrence. (Posted 11/3/23)
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Article : Red flags for colorectal cancer in young adults
Most relevant for: Young adults
The rate of colorectal cancer in young adults has been increasing. Researchers in this study identified four signs or “red flags” for colorectal cancer before age 50 (considered to be early onset colorectal cancer). Recognizing these red flags can help diagnose and treat colorectal cancer earlier. (Posted 10/23/23)
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Update : New first-line treatment option for metastatic prostate cancer
Most relevant for: People with metastatic castration resistant prostate cancer who have an inherited or tumor mutation in certain genes.
The FDA has approved Talzenna (talazoparib) with Xtandi (enzalutamide) as first-line treatments for some patients with metastatic castration-resistant prostate cancer. (Posted 10/2/23)
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Article : Artificial intelligence (AI) may find breast cancer on mammograms sooner
Most relevant for: People interested in the use of artificial intelligence in medicine
Artificial intelligence (AI) tools may help doctors read mammograms. This assistance may lead to earlier diagnoses of breast cancer. (Posted 9/29/23)
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Relevance: High
Quality of Writing: Medium-High
Article : Genetic testing and the future of medicine
Most relevant for: People interested in genetic testing.
An article published in Katie Couric Media discusses genetic testing and how it can impact health. The author talked with Dr. Robert Steiner, a doctor who specializes in genetics. He talked about genetic testing and how the results can affect health and change lives. (posted 9/28/23)
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Relevance: Medium-High
Quality of Writing: High
Topic : Sexual health concerns of gay and bisexual men with prostate cancer
Most relevant for: Gay and bisexual men diagnosed with prostate cancer
Prostate cancer therapy can affect gay and bisexual men differently than heterosexual men. Many urologists do not routinely address these unique concerns. Selecting providers who understand the concerns that are unique to gay and bisexual patients and asking questions about sexual health concerns may improve these patients' healthcare experiences. (Posted 9/21/23)
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