FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you.
XRAY is a reliable source of hereditary cancer research-related news and information.
Learn more about the XRAY program
Categories Prevention, Screening
Relevance: Medium-High


Quality of Writing: Medium-High


Personal Story : A young woman's story of genetic testing and risk-reducing mastectomy
Relevance: Medium-High


Quality of Writing: Medium-High


Most relevant for: Young women of color with a BRCA mutation
Alejandra Campoverdi comes from a family with three generations of breast cancer. As a former White House aide and active educator in the Latina community, she has openly shared her story of genetic testing, her BRCA2 mutation and her plans for risk-reducing mastectomy at age 39. (6/6/19)
Este artículo está disponible en español.
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Relevance: Medium-High


Strength of Science: Medium-High


Study : Do Vitamin B supplements alter breast cancer risk for women with BRCA mutations?
Most relevant for: High risk women with a BRCA1 or BRCA2 mutation
Vitamins are an essential part of our diet. Vitamin supplements are often used to improve general health. This study explores how vitamin B supplements may affect breast cancer risk in women with BRCA mutations. (5/17/19)
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Relevance: Medium-High


Research Timeline: Post Approval


Guideline : Breast surgeons recommend genetic testing for all breast cancer patients
Relevance: Medium-High


Research Timeline: Post Approval


Most relevant for: Anyone diagnosed with breast cancer
The American Society of Breast Surgeons published statement on genetic testing for hereditary breast cancer on February 10, 2019. It includes recommendations about who should be tested. Among these is the recommendation that all breast cancer patients get genetic testing, as well as women who do not have breast cancer but fit the National Comprehensive Cancer Network (NCCN) guidelines. (3/25/19)
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Relevance: High


Strength of Science: Medium-High


Research Timeline: Post Approval


Study : Gaps in information about breast cancer risk and prevention impact African American women
Relevance: High


Strength of Science: Medium-High


Research Timeline: Post Approval


Most relevant for: African American women who are at high risk for breast cancer
A study showed that African American women with increased breast cancer risk experienced greater burdens in obtaining information at each step compared to white women. Racial differences in preventive choices correlated with differences in information and provider access. (3/14/19)
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Relevance: Medium-High


Strength of Science: Medium-High


Research Timeline: Post Approval


Study : Prevalence of BRCA founder mutations in Bahamian women
Relevance: Medium-High


Strength of Science: Medium-High


Research Timeline: Post Approval


Most relevant for: Bahamanian women
The Bahamas has the highest known frequency of BRCA mutations among people diagnosed with breast cancer. This study reviewed whether population-based BRCA testing (testing everyone regardless of family or personal history of cancer) would be an effective approach for finding mutation carriers in the Bahamas. (3/4/19)
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Relevance: Medium-Low


Strength of Science: Low


Research Timeline: Post Approval


Study : Breast cancer implant study suggests links with illness but has serious flaws
Relevance: Medium-Low


Strength of Science: Low


Research Timeline: Post Approval


Most relevant for: Women with or considering breast implant reconstruction
THIS INFORMATION HAS BEEN UPDATED: In October 2021, the FDA issued guidance for people with breast implants Read our latest review on this topic.
An article in the Annals of Surgery, researchers conclude that their work supports an association between silicone breast implants and a range of conditions. This journal article was accompanied by two editorials in which experts voiced their disagreement with the way the analysis was performed and the conclusions of the authors. (2/21/19)
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Relevance: Medium-High


Strength of Science: Medium-High


Study : Breast cancer risk increases modestly after childbirth
Relevance: Medium-High


Strength of Science: Medium-High


Most relevant for: Women in their childbearing years
Does having children alter the risk of breast cancer? Women who give birth have a lower lifetime risk of breast cancer. However, newer data suggests that breast cancer risk increases immediately after childbirth. A study published in December 2018 examines data from the Premenopausal Breast Cancer Collective Group seeking to clarify this issue. (12/28/18)
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Relevance: High


Strength of Science: High


Research Timeline: Post Approval


Study : Can population-based DNA sequencing find more people at risk for hereditary cancers?
Relevance: High


Strength of Science: High


Research Timeline: Post Approval


Most relevant for: Women over age 30
It is well documented that many BRCA mutation carriers are missed using current family history-based screening approaches. As a result, experts are beginning to call for population-based BRCA genetic testing—an organized effort to screen all women like we do for breast and cervical cancer. A recent study looked at whether a population-based genetic testing approach would better identify mutation carriers compared with current practice. (11/17/18)
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Relevance: Medium-High


Quality of Writing: Medium-High


Article : Cancer experience in families affects decision making
Relevance: Medium-High


Quality of Writing: Medium-High


Most relevant for: Women with an inherited mutation linked to increased risk for cancer
Women with inherited mutations in genes that increase breast and ovarian cancer risk have an additional challenge: coping with how those mutations impact their families and how a family member’s cancer experience can shape their own perception. In a recent U.S. News and World Report article, Elaine Howley explores how a woman's decisions about healthcare, cancer prevention and treatment are affected by experience with cancer in the family. (9/25/18)
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Relevance: Medium-High


Strength of Science: High


Research Timeline: Post Approval


Study : Hormone therapy and breast cancer risk after ovary removal in women with a BRCA1 mutation
Relevance: Medium-High


Strength of Science: High


Research Timeline: Post Approval


Most relevant for: Women with BRCA1 mutations who have had risk-reducing ovary removal and have never been diagnosed with breast cancer
Does hormone therapy (HT) alter the risk of breast cancer for woman carrying a BRCA1 mutation who have never been diagnosed with cancer? In this study, researchers showed that among women with BRCA1 mutations, HT use did not increase breast cancer rates for 10 years after ovary removal. More women taking combined estrogen plus progesterone developed breast cancer compared to those taking estrogen only, though this difference was not statistically significant. (9/7/18)
