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FORCE's eXaming the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
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51 through 60 of 212

Relevance: Medium

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Research Timeline: Post Approval

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Guideline : FDA issues warning on CDK inhibitors

Most relevant for: People currently taking a CDK inhibitor

The U.S. Food and Drug Administration issued a safety alert for CDK inhibitors, including Ibrance (palbociclib), Kisqali (ribociclib), and Verzenio (abemaciclib). (9/24/19)

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FDA issues warning on CDK inhibitors

Relevance: Medium-High

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Strength of Science: Medium-High

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Study : Does eating meat affect breast cancer risk?

Most relevant for: Women with a family history of breast cancer

Eating meat has been suggested to increase breast cancer risk. The recent Sister Study looked at meat type, cooking methods and breast cancer risk in a study of 42,012 women.  (9/10/19)

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Does eating meat affect breast cancer risk?

Relevance: High

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Strength of Science: High

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Research Timeline: Post Approval

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Study : Is it safe for BRCA mutation carriers to become pregnant following breast cancer?

Most relevant for: Women with a BRCA mutation who are considering pregnancy after breast cancer

New research shows that pregnancy after breast cancer is safe for women with BRCA mutations and their babies. (9/4/19)

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Is it safe for BRCA mutation carriers to become pregnant following breast cancer?

Relevance: High

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Strength of Science: Medium

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Research Timeline: Post Approval

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Study : Supportive care can improve quality of life for people with metastatic breast cancer

Most relevant for: People diagnosed with metastatic breast cancer

Metastatic breast cancer patients have unique needs for treatment and care. Connecting patients to appropriate support services and palliative care is an area of need in health care. A recent study reported improvement in metastatic breast cancer patient quality of life and wellness with an intervention program called the Supportive, Education and Advocacy (MBC-SEA) program. (8/21/19)

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Supportive care can improve quality of life for people with metastatic breast cancer

Relevance: High

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Strength of Science: Medium-High

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Research Timeline: Post Approval

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Study : MRI or mammograms for detecting breast cancer in families with unknown genetic mutations?

Most relevant for: People with a personal or family history of cancer where no mutation has been found

MRI and mammograms are used together to detect breast cancer in high-risk women who test positive for a BRCA or other gene mutation that increases the risk for breast cancer. For women with a family history of breast cancer but no known genetic mutation, increased screening is recommended. But what method is best? A recent clinical trial in the Netherlands compared MRI and mammography for this population. (8/15/19)

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MRI or mammograms for detecting breast cancer in families with unknown genetic mutations?

Relevance: Medium-High

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Strength of Science: Medium-High

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Study : Diagnosis and treatment delays in young women with breast cancer

Most relevant for: Young women who find a breast lump and young women newly-diagnosed with breast cancer

Young women are more likely to have delays in a breast cancer diagnosis and treatment.  Factors that affect these delays include pregnancy, breastfeeding, financial concerns and having a family history of breast or ovarian cancer. (8/5/19)

Este artículo está disponible en español.

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Diagnosis and treatment delays in young women with breast cancer

Relevance: High

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Research Timeline: Post Approval

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Guideline : FDA asks Allergan to recall certain textured breast implants

Most relevant for: Women with, or considering breast reconstruction with implants

On July 25, 2019, the Food and Drug Administration requested that breast implant manufacturer Allergan recall its BIOCELL textured implants and expanders due to an association with a rare type of lymphoma called Breast Implant Associated Anaplastic Large Cell Lymphoma or BIA-ALCL. The FDA does not recommend removing implants for people who do not have disease symptoms. This XRAYS review updates information about this FDA recall. (7/29/19)

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FDA asks Allergan to recall certain textured breast implants

Relevance: High

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Strength of Science: High

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Research Timeline: Post Approval

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Study : CDK inhibitors may increase survival for ER-positive metastatic breast cancer patients

Most relevant for: People with metastatic, hormone-positive, Her2-negative breast cancer

The phase III MONALEESA-7 study is a clinical trial looking at the effect of a type of treatment known as a CDK4/6 inhibitor in pre- or perimenopausal women with hormone receptor–positive advanced breast cancer. (7/22/19) 

 

 

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CDK inhibitors may increase survival for ER-positive metastatic breast cancer patients

Relevance: High

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Strength of Science: High

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Research Timeline: Human Research

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Study : Results from the POLO trial: Olaparib may delay cancer progression in metastatic pancreatic cancer patients with BRCA mutations.

Most relevant for: People diagnosed with pancreatic cancer who have a BRCA mutation

Note: On 12/27/19, the FDA approved olaparib for treatment of pancreatic cancer in people with a BRCA mutation based on the results of the POLO study.

The POLO clinical trial looks at whether the PARP inhibitor olaparib improves outcomes for those with metastatic pancreatic cancer after platinum-based chemotherapy.  (7/3/19) 

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Results from the POLO trial: Olaparib may delay cancer progression in metastatic pancreatic cancer patients with BRCA mutations.

Relevance: Medium-High

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Strength of Science: High

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Research Timeline: Post Approval

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Study : LGBTQ patients recommend improvements for their cancer care

Most relevant for: LGBTQ cancer patients and their healthcare providers.

Little is known about the cancer care experiences of lesbian, gay, bisexual, transgender and queer (LGBTQ) patients. This study looks at recommendations from the LGBTQ community for improving their cancer care. (6/20/19)

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LGBTQ patients recommend improvements for their cancer care