FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you.
XRAY is a reliable source of hereditary cancer research-related news and information.
Learn more about the XRAY program
All XRAYs
Relevance: Medium-High
Strength of Science: Medium-High
Research Timeline: Post Approval
Study : Benefit of pancreatic cancer screening
Relevance: Medium-High
Strength of Science: Medium-High
Research Timeline: Post Approval
Most relevant for: People with an inherited BRCA1 or BRCA2 mutation
Among people with an inherited mutation in a BRCA1 or BRCA2 gene, screening for pancreatic cancer found most cancers at an earlier stage when they could be treated by surgery. Posted 1/17/24)
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Relevance: Medium-High
Strength of Science: Medium-High
Research Timeline: Post Approval
Study : Genes, genetic counseling and disparities in endometrial cancer
Relevance: Medium-High
Strength of Science: Medium-High
Research Timeline: Post Approval
Most relevant for: People diagnosed with endometrial cancer
Endometrial cancer is on the rise, and it can run in families. Genetic counseling has benefits for people with cancer and their family members. However, Black women with endometrial cancer more often have worse outcomes than white women. Black women with endometrial cancer who test positive for an inherited mutation are less likely to see a genetic counselor. Given these disparities, Black women would benefit from better access to and referrals for genetic counseling. (Posted 12/14/23)
Este artículo está disponible en español.
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Relevance: High
Strength of Science: High
Research Timeline: Post Approval
Study : Immunotherapy improves outcomes of advanced endometrial cancer
Relevance: High
Strength of Science: High
Research Timeline: Post Approval
Most relevant for: People with advanced endometrial cancer
Standard treatment for advanced endometrial cancer may soon change. A study found that people with advanced or recurrent endometrial cancer who received immunotherapy with chemotherapy had better outcomes than those who had chemotherapy alone. (Posted 12/4/23)
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Relevance: Medium
Article : Breast cancer risk for transgender women with inherited mutations
Relevance: Medium
Most relevant for: Transgender women with inherited mutations who are considering or have had gender affirming care
There has been little research on breast cancer risk for transgender women who are at high risk for breast cancer due to an inherited mutation. This review summarizes what we know. (Posted 11/29/23)
Este artículo está disponible en español.
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Relevance: High
Quality of Writing: High
Article : Signs of endometrial cancer: Six survivor stories
Relevance: High
Quality of Writing: High
Most relevant for: Women who want to learn more about the signs of or are at risk for endometrial cancer.
This article shares the experiences of six women diagnosed with endometrial cancer. It highlights the most common signs of endometrial cancer. (Posted 11/16/23)
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Update : New drug combination approved for treatment of BRCA-mutated metastatic prostate cancer
Most relevant for: People with metastatic castration resistant prostate cancer with a mutation in BRCA1 or BRCA2
The FDA approved Akeega (niraparib and abiraterone) plus prednisone for the treatment of BRCA-mutated, metastatic castration-resistant prostate cancer (mCRPC). Akeega can be used as an early or later treatment. (Posted 11/9/23)
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Relevance: Medium-High
Strength of Science: Medium-High
Research Timeline: Post Approval
Study : Pausing hormone therapy to pursue pregnancy does not increase the short-term risk of early-stage cancer recurrence
Relevance: Medium-High
Strength of Science: Medium-High
Research Timeline: Post Approval
Most relevant for: Women with breast cancer who are considering pregnancy
Women who paused hormone therapy treatment of early-stage hormone receptor-positive (HR-positive) breast cancer to attempt to get pregnant had no increase in short-term recurrence. (Posted 11/3/23)
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Article : Red flags for colorectal cancer in young adults
Most relevant for: Young adults
The rate of colorectal cancer in young adults has been increasing. Researchers in this study identified four signs or “red flags” for colorectal cancer before age 50 (considered to be early onset colorectal cancer). Recognizing these red flags can help diagnose and treat colorectal cancer earlier. (Posted 10/23/23)
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Update : New first-line treatment option for metastatic prostate cancer
Most relevant for: People with metastatic castration resistant prostate cancer who have an inherited or tumor mutation in certain genes.
The FDA has approved Talzenna (talazoparib) with Xtandi (enzalutamide) as first-line treatments for some patients with metastatic castration-resistant prostate cancer. (Posted 10/2/23)
Este artículo está disponible en español.
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Article : Artificial intelligence (AI) may find breast cancer on mammograms sooner
Most relevant for: People interested in the use of artificial intelligence in medicine
Artificial intelligence (AI) tools may help doctors read mammograms. This assistance may lead to earlier diagnoses of breast cancer. (Posted 9/29/23)
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