Thinking about cancer or dealing with cancer risk can be scary or overwhelming, but we believe that receiving information and resources is comforting, empowering, and lifesaving.
Inherited mutations in the SKT11 gene are associated with Peutz-Jeghers syndrome, a rare disorder that leads to increased risk of noncancerous growths and increased risk of certain cancers.
People with STK11 mutations are at a greatly increased risk of:
Peutz-Jeghers syndrome also tend to develop noncancerous polyps in the stomach and intestine. Children with this syndrome often have dark spots in or near the mouth, eyes, nostrils and/or fingers.
National guidelines for managing cancer risk in people with inherited
STK11 mutations recommend:
A genetics expert can look at your personal and family medical history and see if it is consistent with
Peutz-Jeghers syndrome and order testing if appropriate.