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Pancreatic Cancer Screening Study for High Risk People
A Pancreatic Cancer Screening Study for High Risk Individuals
About the Study
The purpose of this study is to screen and detect pancreatic cancer and precancer in people with either a strong family history of pancreatic cancer, or an inherited mutation associated with pancreatic cancer risk.
Magnetic Resonance Imaging () will be used to screen for early pancreatic cancer. Participants will also be asked to donate a blood sample at specific intervals for the creation of a blood bank necessary for the development of a blood-based screening test for pancreatic cancer.
What the Study Entails
- Participants will undergo a five-minute psychological survey and donation of a blood sample every 6 months for 3 years.
- will be performed annually for 3 years (4 in total). Cost of will be covered by the study.
- Any abnormalities on the will be reviewed by a multi-disciplinary tumor board and discussed with the study participant.
Men and women 50-80 years of age can participate if:
- They have a strong family history of pancreatic cancer and
- at least two first-degree relatives with pancreatic cancer
- at least three first-, second-, or third-degree relatives with pancreatic cancer with at least one pancreatic cancer in a first degree relative
- They have an inherited mutation in , , CDKN2A, , , , or , or and have at least one first- or second-degree relative with pancreatic cancer.
People are excluded if they:
- Have a prior history of pancreatic cancer or have cancer
- Have a cancer that required post-treatment chemotherapy within the past 5 years
- Received chemotherapy within the past 6 months
- Have hereditary pancreatitis
- Are known to have a severe reaction to a gadolinium contrast or an exam