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GENetic Education Risk Assessment and TEsting Study (GENERATE)

The goal of the GENERATE study is to increase the uptake of genetic testing among family members of pancreatic cancer patients who may carry a genetic mutation.

This study involves education about genetic testing, undergoing genetic testing for cancer risk (for those who choose to) and completion of a series of 4 sets of questionnaires. Note: This study is no longer enrolling patients.

 

Clinicaltrials.gov identifier: NCT03762590


A Study in Advanced Breast Cancer Patients with BRCA 1/2 Mutations Evaluating Olaparib alone or in Combination with Atezolizumab

This is a study for women or men who have been diagnosed with advanced breast cancer with a BRCA 1/2 mutation. The goal of the study is to look at whether giving the PARP inhibitor olaparib in combination with the immunotherapy atezolizumab improves outcomes for patients compared to olaparib alone.  NOTE: This study is no longer enrolling people.

 

Clinicaltrials.gov identifier: NCT02849496
USCF Helen Diller Family Comprehensive Cancer Center


PHACT Study: Population Health and Cancer Testing

NOTE: The PHACT study is no longer recruiting patients. 


Pilot Study of Denosumab in BRCA1 or BRCA2 Mutation Carriers Scheduling Risk-Reducing Salpingo-Oophorectomy

The purpose of this study is to evaluate the effects of denosumab on ovarian cancer risk markers among premenopausal women with a BRCA1 or BRCA2 mutation, who are scheduled to undergo risk-reducing surgery to remove their ovaries and fallopian tubes. UPDATE: THIS STUDY HAS BEEN DISCONTINUED.

Clinicaltrials.gov identifier: NCT03382574


A Study in Hereditary Breast and Ovarian Cancer Families to Provide Men With Up To Date Information About the Personal Importance of Genetic Testing (GEM)

The Genetic Education for Men or GEM study, is a clinical trial evaluating educational tools for men from families in which a BRCA1/2 gene mutation has been identified. In order to identify untested men from BRCA1/2 families, we are seeking women who have received positive BRCA1/2 test results and have at least one untested male relative. NOTE: This study is no longer enrolling people. 

Clinicaltrials.gov identifier: NCT02957981
Bristol Meyers Squibb(TM)


A Phase 2 Study of Nivolumab in Combination with Either Rucaparib, Docetaxel, or Enzalutamide in Men with Castration-resistant Metastatic Prostate Cancer (CheckMate-9KD)

CheckMate-9KD is a clinical research study for men with metastatic prostate cancer (which means cancer that has spread) that no longer responds to treatments that lower testosterone. The purpose of this study is to compare three different combination therapies, each containing a drug called nivolumab and another anti-cancer drug. All three combination therapies are considered investigational, which means that they are not currently approved to treat men with metastatic prostate cancer. The study doctors want to learn more about which therapy is most effective in treating metastatic prostate cancer. NOTE: This study is no longer enrolling. 

Clinicaltrials.gov identifier: NCT03338790


A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy (ATHENA)

ATHENA is a study for women who are newly diagnosed with ovarian cancer. The goal of ATHENA is to look at whether giving maintenance therapy with different agents improves outcomes for women who have completed front-line treatment. UPDATE: THIS STUDY IS NO LONGER ENROLLING PATIENTS

Clinicaltrials.gov identifier: NCT03522246


Decision Navigation for Advanced Prostate Cancer Treatment Options Using mHealth

Men with advanced prostate cancer face difficult choices for treatment because of the nature of their disease and having limited options. This study will test the use of an innovative Registered Nurse-Community Patient Navigator team delivered interactive mHealth decision aid for patients with advanced prostate cancer to help facilitate informed shared decisions about anti-cancer treatment that affects their quality of life. NOTE: This study is no longer enrolling. 

Clinicaltrials.gov identifier: NCT03327103


Safety and Efficacy of Olaparib Alone Or in Combination with Medication Targeting DNA Damaging Repair for Metastatic Triple Negative Breast Cancer

The purpose of this study is to learn the safety and effectiveness of the PARP inhibitor, olaparib as a single drug therapy compared with olaparib in combination with the new agent AZD6738 in patients with metastatic Triple-Negative Breast Cancer (TNBC).  NOTE: This study is no longer enrolling people. 

Clinicaltrials.gov identifier: NCT03330847


Olive Oil for High Risk Breast Cancer Prevention

This study will evaluate the effect of hydroxytyrosol, a component of olive oil, on breast density in women who are at high risk for developing breast cancer. UPDATE: THIS STUDY IS NO LONGER ENROLLING PATIENTS.

 

Clinicaltrials.gov identifier: NCT02068092


Auricular Point Acupressure to Self-Manage Aromatase Inhibitor Musculoskeletal Symptoms in Breast Cancer Survivors

Severe joint pain and muscle stiffness are common side effects of taking Aromatase Inhibitors.  Aromatase inhibitor musculoskeletal symptoms have a negative effect on a woman's physical function and quality of life. Auricular point acupressure uses stimulation applied to points on the ear without using needles. This study will look at and test auricular (ear) point acupressure to manage aromatase-inhibitor-caused joint pain and muscle stiffness in breast cancer survivors. 

Note: This study is no longer enrolling patients.

 

Clinicaltrials.gov identifier: NCT03697200


A Study to Evaluate Rucaparib in Combination With Other Anticancer Agents in Patients With a Solid Tumor (SEASTAR)

This study will look at how safe, effective and tolerable the oral PARP inhibitor Rucaparib is when used in combination with other anticancer agents in patients with advanced solid tumors, including triple-negative breast cancer, ovarian cancer or urothelial cancer. Note: This study has completed enrollment. 

Clinicaltrials.gov identifier: NCT03992131


Study of Safety and Effectiveness of Motiva® Breast Implants

Note: This study is no longer enrolling. 

Clinicaltrials.gov identifier: NCT03579901


The Women Choosing Surgical Prevention (WISP) Trial

The WISP Study is closed to enrollment. Stay tuned for updates from FORCE on study results or new studies for ovarian cancer prevention. 

 

Clinicaltrials.gov identifier: NCT02760849


A Study to Evaluate Rucaparib in Patients with Solid Tumors and with Deleterious Mutations in HRR Genes (LODESTAR)

The LODESTAR study is evaluating the response of the PARP inhibitor rucaparib in people with advanced solid tumors (including breast, ovarian, pancreatic, prostate and other cancers) who have an inherited mutation or an acquired mutation in any of the following genes: BRCA1, BRCA2, PALB2, RAD51C, RAD51D, BARD1, BRIP1, FANCA, NBN, RAD51 or RAD51B.   NOTE: This study is no longer enrolling people.

Clinicaltrials.gov identifier: NCT04171700


A Non-Randomized Phase II Research Study of M6620 (VX-970) in Selected Solid Tumors to Inhibit the ATR Enzyme.

This clinical trial is studying how well M6620 works in treating patients with advanced solid tumors. M6620 is a drug designed to block the ATR enzyme. ATR repairs damaged DNA. In cancer, ATR may protect the cancer cells by helping them repair damage. Blocking ATR may keep cancers from repairing their damaged DNA; slowing the growth of, or killing cancer cells. The study will be recruiting people with different types of cancer, including people with advanced solid tumors and a BRCA1, BRCA2 or ATM mutation.  UPDATE: THIS STUDY IS NO LONGER ENROLLING PATIENTS.

Clinicaltrials.gov identifier: NCT03718091


A Study of IMMray™ PanCan-d Test for Early Detection of Pancreatic Cancer in High-risk Groups

This study will validate and evaluate the performance of the IMMray PanCan-d test for pancreatic cancer diagnosis in comparison to standard of care imaging currently used in pancreatic cancer disease surveillance by the research sites’ institutions. ENROLLMENT HAS CLOSED FOR THIS STUDY!

Clinicaltrials.gov identifier: NCT03693378


INTense Exercise foR surVivAL Among Men With Metastatic Castrate-Resistant Prostate Cancer (INTERVAL)

This study will determine if high intensity aerobic and resistance training (with supervised exercise) plus psychosocial support increases overall survival compared to psychosocial support alone (with self-directed exercise) in patients with metastatic castrate-resistant prostate cancer. NOTE: This study is no longer enrolling people. 

Clinicaltrials.gov identifier: NCT02730338


Making Genetic Testing Accessible (MAGENTA)

The goal of this research study is to test the effects of online genetic education alone or in combination with telephone genetic counseling in order to compare the two methods and the stress a person feels about their risk of cancer.  NOTE: This study has closed for enrollment.

Clinicaltrials.gov identifier: NCT02993068


IMProving Executive function Study

Dr. C. Neill Epperson and her research team at the Penn Center for Women's Behavioral Wellness are studying the effects of a stimulant medication called Vyvanse® on memory and attention in women who had surgery to remove their ovaries to lower their risk for ovarian cancer (risk-reducing salpingo-oophorectomy or RRSO). NOTE: The study offers travel reimbursements and hotel accommodations for those eligible to participate. 

NOTE: This study is no longer enrolling people. 

Clinicaltrials.gov identifier: NCT03187353


Olaparib as Adjuvant Treatment in Patients With Germline BRCA Mutated High Risk HER2 Negative Primary Breast Cancer. (OlympiA)

The OlympiA trial is the first major study to test a targeted therapy for people with BRCA mutation-associated breast cancer in the adjuvant setting (after surgery) for people with earlier-stage (stage 2 or stage 3) cancers. The OlympiA trial has now completed enrollment. Interim results from OlympiA were presented at the 2021 ASCO Annual Symposium. 

Clinicaltrials.gov identifier: NCT02032823


Dose-Response of Aerobic Training in Post-Menopausal Women at High-Risk for Development of Breast Cancer

In this study, researchers wanted to determine the optimal amount of exercise needed to change certain factors associated with breast cancer risk for post-menopausal, high-risk women. 

NOTE:  THIS STUDY ENROLLMENT HAS CLOSED

Clinicaltrials.gov identifier: NCT02494869


Prospective Registry Of MultiPlex Testing (PROMPT)

PROMPT is an online research registry for people who have had genetic panel testing (also known as multiplex testing) — a newer form of genetic testing that looks for mutations in several different genes at once. All genes on the panels have been linked to an increased risk of cancer, but some risks are better known than others.

The goal of the PROMPT Registry is to follow people with mutations or variants in genes on these panels, so that patients, physicians, and researchers can more clearly understand these lesser-known risks.

Clinicaltrials.gov identifier: NCT02665195
Rush University Medical Center


Serum Folate in Patients Treated with Olaparib

This is a study looking at folate deficiency (lack of folic acid in the blood) in patients who take the drug olaparib (Lynparza) to treat their advanced ovarian or breast cancer. The main goal of this study is to measure how often and when folate deficiency is most likely to occur; and to learn more about whether giving folic acid supplements (vitamins) will help delay or avoid deficiency in these patients. Folate deficiency can cause side effects and lead to reduction or stopping of treatment with olaparib.  NOTE: This study is no longer enrolling people.

Clinicaltrials.gov identifier: NCT04024254


Talazoparib Beyond BRCA (TBB) Trial

The goal of the study is to evaluate the anti-cancer activity of Talazoparib (a type of treatment known as a PARP inhibitor) in patients with advanced breast cancer with specific genetic mutations based on a blood, saliva, or tumor test. See the clinicaltrials.gov listing for additional information. NOTE: This study is no longer enrolling people.

Clinicaltrials.gov identifier: NCT02401347


ARIEL4: A Study of Rucaparib Versus Chemotherapy BRCA Mutant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients

ARIEL4 is a treatment study for women with relapsed, high-grade epithelial ovarian, fallopian tube, or primary peritoneal cancer who have a BRCA1 or BRCA2 mutation. ARIEL4 is designed to evaluate rucaparib against standard of care chemotherapy in women who have had at least two prior chemotherapy regimens.  UPDATE: THIS STUDY IS NO LONGER ENROLLING PATIENTS

Clinicaltrials.gov identifier: NCT02855944
Additional Results on Clinicaltrials.gov
1000 results
Clinical Trial Official Title
NCT03941379 A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma
NCT07226986 A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI in Adult Participants With PSMA-positive mCRPC
NCT05206331 CEM to Reduce Biopsy Rates for Less Than Highly Suspicious Breast Abnormalities: a Prospective Study
NCT06543537 Pilot Randomized Controlled Trial of a Collaborative Agenda-setting Intervention (CASI) for Patients With Ovarian Cancer
NCT07121972 Mirai-MRI: Validation of AI Models for Breast Cancer Risk
NCT05930483 Remotely Delivered, Community-Aligned Weight Loss Interventions Among Breast Cancer Survivors, ¡Vida! Trial
NCT06051695 A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
NCT05832086 Intermittent Fasting Using a Fasting-Mimicking Diet to Improve Prostate Cancer Control and Metabolic Outcomes
NCT06096870 Enzalutamide and PDS01ADC in PET Positive Recurrent Prostate Cancer (pprPC) Without Testosterone Lowering Therapy
NCT06795529 Targeted Palliative Care Intervention for Patients With Metastatic Breast Cancer
NCT05256745 RAGE Inhibition to Decrease Cardiotoxicity in Women With Early Breast Cancer
NCT05585788 Opioid Dispensing Device for Post-Operative Pain in Cancer Patients
NCT04986423 ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer
NCT07067788 B.Brilliant Revelation Comparision Study
NCT01776905 In Vivo Real-time Detection of Circulating Melanoma Cells
NCT03937453 A Pancreatic Cancer Screening Study in Individuals With New-Onset or Deteriorating Diabetes Mellitus
NCT03808337 Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease
NCT06972875 Fezolinetant for Treating Hot Flashes in Men With Prostate Cancer
NCT04981119 Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
NCT05733000 CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors
NCT05941520 Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer
NCT06454383 Gemcitabine and Leflunomide in Patients With Advanced Unresectable Pancreatic Cancer
NCT06833502 Phase II Study of Systemic Screening in Pathologic Node Positive Breast Cancer
NCT06710756 Lead-212 PSV359 Therapy for Patients With Solid Tumors
NCT03067051 Clinical Study to Assess the Safety and Efficacy of the SpectraCure P18 System
NCT06336902 Botensilimab Plus Balstilimab and Fasting Mimicking Diet Plus Vitamin C for Patients With KRAS-Mutant Metastatic Colorectal Cancer
NCT04360330 SABER Study for Selected Early Stage Breast Cancer
NCT05178498 Impact of Dietary Inflammatory Potential on Breast Cancer Risk
NCT06096623 The Care Tracker Study: Using Patient-Reported Data to Address Racial Disparity in Cancer Treatment
NCT04134780 Ultrasound Imaging and Spectroscopy as Early Indicators of Locally-Advanced Breast Cancer Response
NCT06171269 Using MRI to Identify Areas to Receive Lower Doses of Radiation Treatment in Men With Prostate Cancerdose Mapping to Preserve Quality of Life
NCT05840263 Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer
NCT03646617 Ipilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic Melanoma
NCT06084013 Use Of Indocyanine Green In Pancreas Surgery
NCT07288203 A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Melanoma
NCT06303505 FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC
NCT05141513 Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma
NCT06639724 Perioperative Fostamatinib With Gemcitabine and Nab-paclitaxel in Resectable Pancreatic Cancer
NCT07007559 ASPEN-09: A Study of Evorpacept in Combination With Anti-cancer Therapies in Advanced / Metastatic Malignancies
NCT06312176 A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
NCT03334708 A Study of Blood Based Biomarkers for Pancreas Adenocarcinoma
NCT07287917 Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors
NCT06026410 KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
NCT04119024 Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors
NCT06252649 Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
NCT04956640 Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)
NCT06998940 Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations
NCT06639074 Folate Receptor Alpha Dendritic Cells (FRαDCs) or Placebo for the Treatment of Patients With Stage III or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer, FAROUT Trial
NCT04074720 Prospective Breast Cancer Biospecimen Collection
NCT07049276 The Multicentre Selective Lymphadenectomy Trial - 3
NCT05103683 First in Human Study of TORL-1-23 in Participants With Advanced Cancer
NCT06117241 Reducing Metabolic Dysregulation in Dyads
NCT07148245 Symptoms of Immune Checkpoint Inhibitor Therapy in Cutaneous Melanoma
NCT04084730 Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer
NCT06862856 Flotufolastat F 18 PET in Men With Very Low PSA Recurrence
NCT07136077 A Phase 2 Trial of Fruquintinib and Tislelizumab in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy
NCT06937177 Safely Optimizing Body Weight With TCMCB07 in Patients With Newly Diagnosed Metastatic Colorectal Cancer Undergoing Chemotherapy
NCT05417867 Evaluating the Association Among Changes in Gut Microbiome, Fatigue, and Chemotherapy-Induced Nausea in Early Stage Breast Cancer
NCT06710067 Urine Metabolites in the Diagnosis of Disease
NCT05559164 Statins for Reduction of Cardiac Toxicity in Patients Receiving HER2 Targeted
NCT06138067 Patient Navigation Program to Improve Clinical Trial Enrollment in Cancer Patients
NCT06326411 A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors
NCT05288777 Adjuvant Chemoradiation and Biomarkers of Response in High-risk Breast Cancer
NCT02478892 Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk
NCT06625034 Radiation Therapy With RapidPlan Knowledge-based Planning vs Human-Driven Planning for Treatment of Prostate Cancer
NCT06528990 Telehealth Intervention for Ostomy Self-Management
NCT05803382 Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers
NCT07182279 Neoadjuvant High Dose Rate Brachytherapy Prior to Radical Prostatectomy in Patients With Prostate Cancer
NCT06059118 Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer
NCT04930991 High Dose Omeprazole in Patients With Pancreatic Cancer
NCT07127874 A Study of PHN-012 in Patients With Advanced Solid Tumors
NCT06815354 Comprehensive Assessment of Cancer Theranostic Response
NCT06380751 Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer
NCT04797039 MRI-Guided Cryoablation for Focal Native Prostate Cancer
NCT05130801 A Study of Multiparametric MRI and pHLIP® ICG in Breast Cancer Imaging During Surgery
NCT05616650 Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor
NCT06710288 A Phase 2, Open-label, Single-arm Study Of Autologous M-CENK Adoptive Cell Therapy And N-803 (IL-15 Superagonist) In Combination With Gemcitabine In Participants With Recurrent Platinum-Resistant High-Grade Ovarian Cancer
NCT03692429 alloSHRINK - Standard cHemotherapy Regimen and Immunotherapy With Allogeneic NKG2D-based CYAD-101 Chimeric Antigen Receptor T-cells
NCT05894239 A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer
NCT07068477 Adaptation of a Values Assessment Tool
NCT05856981 Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors
NCT05424783 MRI And GPS Informing Choices for Prostate Cancer Treatment (MAGIC)
NCT06465966 UFPTI 2403-PR12: Real-Time Volumetric Ionizing Radiation Acoustic Imaging for In-vivo Proton Treatment Monitoring in Pencil-Beam Scanning
NCT04787042 Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067
NCT06662786 A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
NCT01365169 Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"
NCT04550494 Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations
NCT06833866 Phase I Trial of 5-Fluorouracil (5FU) -Based Therapy in Combination With Hydroxytyrosol (HT) in Patients With Advanced or Metastatic Colorectal Cancer
NCT05694559 Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics
NCT05058846 Pilot Study of Pancreatic Cancer Screening
NCT06226129 Gadopiclenol in Contrast Enhanced MRI of the Prostate
NCT06898996 FITting Non-invasive Tests in Lynch Syndrome Surveillance
NCT07214662 A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-0587 as a Monotherapy and in Combination With Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive and Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer
NCT07278986 CYTALUX for Intraoperative Imaging of Patients With Endometrial Cancer
NCT04553770 Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer
NCT04739072 Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study
NCT05548296 A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma
NCT07166042 Guided Meditation During Radiation Therapy for Breast and Gynecological Malignancies
NCT06781983 Safety and Tolerability of IPH4502 in Patients With Advanced Solid Tumors
NCT07419841 A Phase 1 Study of the Safety and Tolerability of CTX-10726
NCT07001241 Telehealth Exercise Program Evaluating Fatigue and Physical Function in Rural Cancer Survivors
NCT04812366 Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer
NCT07214883 UCF MammoChat: Image Repository
NCT07011654 Study of Naxitamab and Sacituzumab Govitecan in Patients With Metastatic Triple-negative Breast Cancer (TNBC)
NCT05839912 Excision of Lymph Node Trial (EXCILYNT) (Mel69)
NCT07389967 Nutrition Awareness Among Women With Non-Metastatic Breast Cancer
NCT06657144 A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors
NCT06813053 A Novel Patient Decision Aid for Surgical Treatment Options in Early-Stage Breast Cancer
NCT06042569 Dose-Reduced Docetaxel With Cyclophosphamide for the Treatment of Vulnerable Older Women With Stage I-III HER2 Negative Breast Cancer, the DOROTHY Trial
NCT06634875 Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS)
NCT06941857 NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients With Untreated Metastatic Pancreatic Cancer
NCT06802172 Effect of Meal Timing During Cancer Treatment in Patients in Alaska: A Randomized Clinical Trial
NCT07077239 Prostate Cancer Postoperative Stereotactic Body Radiotherapy With Adaptive Technology for Minimizing Toxicity
NCT05316129 Infusion of Autologous T Cells Engineered to Target FSH Receptor in Recurrent Ovarian Cancer
NCT07189195 TR-002 for the Treatment of Advanced, Unresectable or Metastatic Solid Tumors and Unresectable or Metastatic, Refractory Pancreatic Adenocarcinoma
NCT04020575 Autologous huMNC2-CAR44 or huMNC2-CAR22 T Cells for Breast Cancer Targeting Cleaved Form of MUC1 (MUC1*)
NCT05488145 A Feasibility Trial of a Web Based App Intervention in Hormone Positive Breast Cancer Patients to Improve Adherence to Endocrine Therapy
NCT06523777 PRISM: Patient Experiences With PET Imaging in Prostate Cancer
NCT06795009 Zanzalintinib in Combination With Paclitaxel in Recurrent High Grade Uterine Cancer
NCT06365619 Neoadjuvant Ipilimumab/Nivolumab for Patients With Recurrent, High Risk, Resectable Melanoma
NCT07227636 A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and Chemotherapy
NCT04722692 Delayed Sentinel Lymph Node Biopsy in Ductal Cancer in Situ
NCT06437574 Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer
NCT04167969 The Use of Nanoparticles to Guide the Surgical Treatment of Prostate Cancer
NCT07207564 Integrating Molecular Pathology, Radiology, and Genetics to Improve Breast Cancer Risk
NCT06011499 Internet-Based Lifestyle Intervention to Eradicate Obese Frailty in Prostate Cancer Survivors, iLIVE
NCT07218809 AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer
NCT05155046 18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy
NCT07327489 Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies
NCT02977468 Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancer
NCT05746182 Genetic Predisposition Testing Program for Pancreatic Neuroendocrine Neoplasms
NCT03877796 Clinical Pre-screening Protocol for Ovarian Cancer
NCT06398418 R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid Tumors
NCT06749210 DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY
NCT06629779 A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
NCT05968690 Naltrexone and Propranolol Combined With Immunotherapy
NCT06698146 Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection
NCT06451497 This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors
NCT06949410 HER2 Vaccine for Locally Advanced Breast Cancer
NCT07146568 Evaluating the Implementation and Effectiveness of the Pink and Pearl Campaign on Lung Cancer Screening at Christian Hospital
NCT07213674 A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
NCT02918474 Decision Making Tool in Supporting Decision Making in Contralateral Prophylactic Mastectomy in Patients With Newly Diagnosed Breast Cancer
NCT06134232 Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + One Infusion of Sipuleucel-T
NCT06504147 A Study of Radspherin® in Patients With Primary Advanced Epithelial Cancer, With Peritoneal Metastasis That Are Homologous Recombination Proficient Scheduled to Undergo Neoadjuvant Chemotherapy and Interval Debulking Surgery
NCT06966050 Multi-center MRD Registry for Inflammatory Breast Cancer
NCT05232916 Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
NCT07160335 A Phase I Clinical Study to Evaluate the PK Profile, Efficacy, Safety and Immunogenicity of HLX17 vs. Keytruda® in Multiple Resected Solid Tumors
NCT06046040 TmPSMA-02 in mCRPC
NCT06294574 Improved Successful Retrieval Rate of HydroMARK Plus Breast Biopsy Site Marker in Comparison to HydroMARK as Well as Improved Surgeon Satisfaction
NCT05765500 RecoverPC: Relugolix vs GnRH Agonist in Quality of Life
NCT06376604 Fasting Mimicking Diet in Chemotherapy of Gynecologic Malignancies
NCT07213804 A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer
NCT06409052 Endometrial Cancer, Risk Factors and Prevention Strategies: Perspectives of Patients and At-Risk Women
NCT04472338 Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study
NCT02332668 A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)
NCT04486755 Hypofractionated Accelerated Pelvic Nodal Radiotherapy (GCC 2048)
NCT06190899 Gedatolisib in Combination With Darolutamide in Metastatic Castration-Resistant Prostate Cancer
NCT03729115 A Multi-Modality Surveillance Program for Women at High Risk for Breast Cancer
NCT05732623 Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer
NCT05627960 First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor Malignancies
NCT04611568 War on Melanoma™ Public Health & Education Campaign
NCT06184750 Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial
NCT02926690 Safety Study of MELK Inhibitor to Treat Patients With Advanced Breast Cancer and Triple Negative Breast Cancer
NCT04763980 Community-Based Health Coach for Access to Germline Genetic Testing Among African American Men With Prostate Cancer
NCT05969860 At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
NCT05447923 Addressing Disparities in Colorectal Cancer Screening in Black and Underserved Phoenix Communities
NCT05563220 Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer
NCT07044362 Histotripsy Plus Chemotherapy vs Chemotherapy Alone for Advanced Colorectal Liver Metastasis
NCT07238023 Promoting Active Living Among People With Metastatic Breast Cancer
NCT07206056 An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)
NCT07231159 Building on Trust: Navigating Preventive Lung, Breast, and Prostate Cancer Screenings at Community Resource Spots
NCT06472661 FUSA With Intratumoral PolyICLC in Regionally Advanced Resectable Melanoma
NCT05958082 Utilization of Educational Interventions in Completion of Genetic Testing in Black Patients With High-Risk Prostate Cancer
NCT07164027 Comparing a New PSMA Imaging Agent to MRI for Detecting Prostate Cancer, BEACON Trial
NCT06212583 High-Risk Metachronous Oligometastatic Prostate Cancer Trial
NCT06252662 Liposomal Bupivacaine Vs Bupivacaine with Dexmedetomidine in Erector Spinae Plane Blocks for Mastectomies
NCT05524935 Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma
NCT05020860 Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer
NCT02743858 Lymphedema Surveillance Study
NCT07226115 Splicing-based Predictive Learning for Individual Chemotherapy Evaluation in Colorectal Cancer
NCT07424547 Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors
NCT05624918 A Study of NovoTTF-200T(P) in Combination With Gemcitabine and Nab-Paclitaxel for Resectable Pancreatic Adenocarcinoma
NCT06915025 Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal Cancer
NCT07364474 Immune Response to Percutaneous Hepatic Perfusion With Melphalan for Ocular Melanoma Metastatic to the Liver
NCT06965192 Designing Visual Tools to Enhance Cancer Surgeon Decision-making
NCT04858009 Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis
NCT06624644 A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma
NCT06564571 Artificial Intelligence in Endoscopic Ultrasound
NCT05242744 FTT PET/CT in Metastatic Prostate Cancer
NCT06855654 Promoting Resilience in Women With Breast Cancer (PRISM -MBC)
NCT06072807 Brain [18F]-FES PET/CT in Patients With Estrogen-Receptor Positive Breast Cancer
NCT04862663 Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)
NCT06526819 SMP-3124LP in Adults With Advanced Solid Tumors
NCT04903119 Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma
NCT00477100 Biospecimen and Medical Data Collection and Tumor Biopsy in Creating Research Tissue Registry in Patients With Inflammatory or Invasive Breast Cancer
NCT02402244 Project: Every Child for Younger Patients With Cancer
NCT06549465 Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer (CRPC)
NCT04489719 Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer
NCT06168487 Telmisartan in Prostate Cancer
NCT03093909 Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases
NCT05523947 Clinical Trial of YH32367 in Patients With HER2 Positive Locally Advanced or Metastatic Solid Tumor
NCT05809752 A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)
NCT06757192 CRC Screening in Unscreened Individuals 45-54
NCT07208084 Project SOAR (Speaking Our African American Realities) Awakenings for Black American Women Diagnosed With Breast Cancer
NCT05130255 GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2
NCT06743126 SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma
NCT06200103 Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer
NCT06730750 A Study of BMS-986490 With or Without Bevacizumab in Advanced Solid Tumors
NCT06200259 Reduction of Gastrointestinal Toxicity in Prostate Cancer by Proton Spot Placement
NCT06303713 LuCarbo - a Study of 177Lu-PSMA-617 Plus Carboplatin in Metastatic Castrate-resistant Prostate Cancer
NCT06646627 Clinical Trial of Autologous B7-H3 CAR T Cells in Reoccurent Platinum-resistant Ovarian Tumors
NCT01961713 Circulating Tumor Cell Analysis in Patients With Localized Prostate Cancer Undergoing Prostatectomy
NCT06966024 Study of DCC-2812 in Participants With Advanced Genitourinary Cancers
NCT04789486 Nano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic Cancer
NCT03743298 Safety of AV-MEL-1 With Anti-PD-1 Therapy in Metastatic Melanoma
NCT06249048 Phase 1/2 Study of Intratumoral Injection of STX-001 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab
NCT05372640 Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors
NCT03384238 Panitumumab-IRDye800 in Patients With Pancreatic Cancer Undergoing Surgery
NCT06589440 Phase 2 Study of SR-8541A in Combination With Botensilimab and Balstilimab in Subjects With Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)
NCT05923684 NLP-Based Feedback to Improve Risk Comms and Informed Shared Decision Making
NCT05142033 Avera Cancer Sequencing and Analytics Protocol (ASAP)
NCT06244004 FDG-PET-Guided Metastasis Directed Radiation Therapy for the Treatment of Metastatic Hormone Sensitive Prostate Cancer, The PRTY Trial
NCT05193149 Inspiratory Muscle Training in Obese Breast Cancer Survivors
NCT05826743 Safety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the Ileostomy
NCT04305834 Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.
NCT06434064 Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast Cancer
NCT07291414 A Self-Monitoring Platform for Tracking Medication Safety and Concerns in Cancer Patients
NCT02250352 Core Biopsies for Establishing a Breast Tumor Tissue Repository
NCT06428721 The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Population
NCT07078604 A Cancer Vaccine (STEMVAC) in Combination With Chemotherapy for the Treatment of PD-L1 Negative Metastatic Triple-Negative Breast Cancer
NCT06113016 Prevention of Frailty With Fisetin and Exercise in Breast Cancer Survivors
NCT03824145 Every Day Counts: A Lifestyle Program for Women With Metastatic Breast Cancer
NCT07227077 Dosing Physical Activity Among Older Cancer Survivors Who Experience Chronic Pain: a Micro-randomized Trial
NCT05039801 IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors
NCT05287451 Risk Reducing Salpingectomy With Delayed Oophorectomy as an Alternative to Risk- Reducing Salpingo-oophorectomy in High Risk-Women to Assess the Safety of Prevention - US Cohort Study
NCT06789172 A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors
NCT06130995 Relugolix + Enzalutamide Study in High-Risk Prostate Cancer
NCT03556228 VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
NCT07032545 Metabotyping of Broccoli Microgreen in Obese Breast Cancer Survivors
NCT06324357 Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
NCT06787612 Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer
NCT05077137 A Feasibility Study Utilizing Immune Recall to Increase Response to Checkpoint Therapy
NCT05877430 Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer
NCT05461430 Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)
NCT07383649 Trial to Study Anti- HCMV Therapy in Breast Cancer Patients With Progressive Intracranial Metastases and CMV Infection
NCT04624555 The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors
NCT06817226 BREAST Choice Decision Tool R21 - AIM2
NCT05972343 COOL-IT-PRO: Cryoablation of Breast Cancer in Non-surgical Patients
NCT05227326 AOH1996 for the Treatment of Refractory Solid Tumors
NCT01638676 A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients
NCT06371768 Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors
NCT07192614 A Study to Learn How Safe AZD6621 is, How Well it Works, and How it Moves Throughout the Body Over Time, in Adult Male Participants With Metastatic Prostate Cancer
NCT06553885 Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC
NCT05746325 Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast or Lung Cancer
NCT06805825 A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit
NCT06340620 EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope
NCT05549297 Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)
NCT06369259 Open-label Phase 2 Study of Avutometinib (RAF/MEK Clamp) in Combination With Defactinib (FAK Inhibitor) and Cetuximab in Patients With Unresectable, Anti-EGFR-Refractory Advanced Colorectal Cancer
NCT05507879 TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer
NCT06773897 Rutgers University Study of the Genetics of Breast Cancer.
NCT06885203 Social and Environmental Determinants of Breast Cancer Survivorship: the Black Breast Cancer Survivor's Intervention (BBCSI)
NCT06551324 A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).
NCT07027124 Neoadjuvant ADT + Darolutamide With Pembrolizumab, Followed by Adjuvant Pembrolizumab in Molecularly Stratified High-Risk Prostate Cancer
NCT04332588 Monitoring HER2+ Breast Cancer Neoadjuvant Treatment With Advanced PET/MRI
NCT05929820 Impact of Protect Your Colon™ on CRC Screening
NCT05930496 Evaluating the Effects of an Exercise Intervention on the Gut Microbiota in Stage II-III Colorectal Cancer Survivors
NCT06267729 Study of AZD0754 in Participants With Metastatic Prostate Cancer
NCT05570253 A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer
NCT06535802 iCCaRE Consortium Pilot Project 1: Feasibility of a Point of Prostate Cancer Diagnosis Intervention for Newly Diagnosed Black Men
NCT05535894 Endoscopic Radiofrequency Ablation of Celiac Ganglion for Pain Management and Improvement of Quality of Life in Patients With Unresectable Pancreatic Cancer
NCT06253494 Pembrolizumab, Lenvatinib and IL-15 Superagonist N-803 in Combination With HER2 Targeting Autologous Dendritic Cell (AdHER2DC) Vaccine in Participants With Advanced or Metastatic Endometrial Cancer
NCT04878094 A Study of Intra-operative Imaging in Women With Ovarian Cancer
NCT05997615 Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer
NCT06586047 Breast Cancer PSMA PET
NCT07271017 Robot-Assisted Prostate Biopsy With a Novel Ultrasound Probe
NCT07492927 Plasma exoRNA-Based Liquid Biopsy to Diagnose Clinically Significant Prostate Cancer
NCT06389097 SPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization
NCT06518746 Gonadal Dysgenesis Tissue Cryopreservation for Fertility Preservation
NCT05932862 A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors
NCT06369246 PRORAD-5 PROstate RADiation in 5 Fractions: Phase II Five Fraction Radiotherapy for Patients With Advanced Prostate Cancer.
NCT04396808 Genomics in Michigan to AdJust Outcomes in Prostate canceR (G-MAJOR) for Men With Newly Diagnosed Favorable Risk Prostate Cancer
NCT06814496 Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors
NCT05134779 De-convoluting Interactions Between Genes, the Cancer Environment, and the Immune System to Develop Therapies That Work for You
NCT05630794 Testing for Safety and Colorectal Cancer Preventive Effects of ONC201
NCT04802759 A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer
NCT05223803 TERPS Trial for de Novo Oligometastic Prostate Cancer
NCT07225270 Study to Assess the Efficacy and Safety of Rina-S Plus Standard of Care Compared to Standard of Care for Maintenance Treatment of Participants With Recurrent Platinum-sensitive Ovarian Cancer After Second-line (2L) Platinum-based Doublet Chemotherapy
NCT05129605 Prostate Cancer Genetic Risk Evaluation and Screening Study
NCT06288113 Re-treatment With 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer, RE-LuPSMA Trial
NCT06826924 7-Days Water-Only Fasting Trial in Prostate Cancer
NCT06625983 Use of a Colorectal Cancer Screening Decision Support Tool in Primary Care
NCT05704283 3D Ultrasound for the Imaging of Lymph Nodes in Patients With Breast Cancer
NCT07043270 24BRO681 : Alternating Gnp and mFOLFIRINOX for BR-PDAC
NCT06127979 A Study of Changes in Ki67 Expression in People With Breast Cancer Receiving Endocrine Therapy Before Surgery
NCT03935893 Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers
NCT05754658 African Cancer Genome: GMD
NCT06296147 Virtual Reality Headset and/or Aromatherapy for Patients Undergoing a Transperineal Prostate Biopsy
NCT06246968 A Study of Pembrolizumab and Cryoablation in People With Breast Cancer
NCT00588185 [18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone Pet Imaging in Patients With Progressive Prostate Cancer
NCT01913106 HSV-tk + Valacyclovir Therapy in Combination With Brachytherapy for Recurrent Prostate Cancer
NCT06488378 Phase Ib Study of Axatilimab in Combination With Olaparib in BRCA1/2 and PALB2- Associated Metastatic HER2-negative Breast Cancer
NCT06817668 Evaluating Tolerability of ePUHRT With Brachytherapy Boost
NCT04548817 Neurocutaneous Melanocytosis Registry
NCT06171607 Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses
NCT06507930 The COMPASSION Study
NCT04775355 Study to Detect Changes in Urinary and Gut Microbiome During Androgen Deprivation Therapy and Radiation Therapy in Patients With Prostate Cancer
NCT05673148 Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study
NCT07211178 Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies
NCT04975217 Fecal Microbial Transplants for the Treatment of Pancreatic Cancer
NCT03250078 A Pancreatic Cancer Screening Study in Hereditary High Risk Individuals
NCT05417308 Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer
NCT05983276 Decitabine and Selinexor in Combination to Reverse Drug Resistance With Standard Chemotherapy in Ovarian Cancer
NCT04799535 Quantitative Microvasculature Imaging for Breast Cancer Detection and Monitoring
NCT07042243 The Florida ASCENT Study
NCT02732171 PENN-Surveillance Markers of Utility for Recurrence After (Neo)Adjuvant Therapy for Breast Cancer
NCT07210086 Phase II Non-Randomized Study Evaluating POSLUMA-PSMA PET Response After Oligo- Metastatic/Progressive-directed Treatment With Radiotherapy (PROMPT-R)
NCT05645380 Neoadjuvant TIL- and Response-Adapted Chemoimmunotherapy for TNBC
NCT03050268 Familial Investigations of Childhood Cancer Predisposition
NCT06666790 DermaSensor Postmarket Surveillance Study
NCT05462496 Modulation of the Gut Microbiome With Pembrolizumab Following Chemotherapy in Resectable Pancreatic Cancer
NCT06339827 ASk Questions in GYnecologic Oncology (ASQ-GYO)
NCT05313191 Prospective Evaluation of Pencil Beam Scanning Proton Therapy for Previously Irradiated Tumors
NCT05259410 Time Restricted Eating During Chemotherapy for Breast Cancer
NCT06393374 Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
NCT07122713 Definitive Radiation Therapy for Inoperable Breast Cancer
NCT06807359 Photodynamic Therapy of Primary Localized Prostate Cancer With the SpectraCure P18 System
NCT06409390 Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer
NCT06897488 EMERALD: Endocrine Therapy oMission With Radiation in ER+ Breast Cancer: Assessing Quality of Life and Disease Control: a Prospective Phase II Trial
NCT05913713 HIIT Following Breast Cancer Chemotherapy
NCT06691035 Immunologic Targeting of ESR1 Receptor for Hormone Receptor Expressing Metastatic Breast Cancer
NCT06179160 A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
NCT02830724 Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers
NCT05144698 RAPA-201 Therapy of Solid Tumors
NCT06460298 ProAgio in Combination With Gemcitabine in Patients With Metastatic Triple Negative Breast Cancer
NCT05455619 Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer
NCT04469764 Abemaciclib for the Treatment of Recurrent Ovarian or Endometrial Cancer
NCT06625775 Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
NCT03652428 Phase I Nab-Paclitaxel Plus Gemcitabine With Proton Therapy for Locally Advanced Pancreatic Cancer (LAPC)
NCT05743621 Study of TVB-2640 in Men With Metastatic Castration-Resistant Prostate Cancer
NCT06785636 Open-Label Study of Pocenbrodib Alone and in Combination With Abiraterone Acetate, Olaparib, or 177Lu-PSMA-617
NCT07044336 Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)
NCT02701244 A Registry Study of Breast Microseed Treatment
NCT04985032 Accelerated Partial Breast Irradiation (APBI) Using Stereotactic Body Radiation Therapy (SBRT)
NCT05983432 Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
NCT04230109 Sacituzumab Govitecan In TNBC
NCT02997709 Collection and Measurement of Biomarkers in Prostate Cancer Radiotherapy Patients
NCT05716516 STUDY02001740;22SCH740: Estradiol For ER+ Advanced Breast Cancer (ESTHER)
NCT05327608 Neoadjuvant Breast Cancer Time Restricted Eating
NCT06952504 A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
NCT07130708 Exploring the Potential of Robotic Telesurgery in Remote Settings
NCT02871726 Transrectal Ultrasound Robot-Assisted Prostate Biopsy
NCT04683315 PurIST Classification-Guided Adaptive Neoadjuvant Chemotherapy by RNA Expression Profiling of EUS Aspiration Samples
NCT07032584 Impact of Multimodal Telerehabilitation in Rural Patients With Metastatic Prostate Cancer
NCT07368998 To Study the Effect of Inavolisib in Combination With Fulvestrant in Participants With Breast Cancer
NCT06824467 A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
NCT07158164 DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment
NCT06230185 CtDNA Based MRD Testing for NAC Monitoring in TNBC
NCT07393906 Colorectal Cancer Prevention Research Study: Eat Right, Screen Right
NCT05752448 Survivorship Care for Women Living With Ovarian Cancer: (POSTCARE-O)
NCT04055649 ONC201 Plus Weekly Paclitaxel in Patients With Platinum Refractory or Resistant Ovarian Cancer
NCT06275126 Optimizing Surgical Decisions in Young Adults With Breast Cancer
NCT06065748 A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)
NCT05573126 Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer
NCT04258280 Improving Genetic Counseling for BRCA+ Mothers
NCT04923178 A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract Malignancies
NCT00488878 Data Collection for Patients With Low Grade Ovarian or Peritoneal Tumors
NCT06271291 Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts
NCT03558048 The Effect of IBD Flares on Serum PSA
NCT05790213 Prostate Cancer Treatment Using Androgen Deprivation Therapy and Focal Prostate Ablation
NCT05497024 Older Men's Decision Making About Active Surveillance for Prostate Cancer - Aim 3: Decision Aid Cognitive and Usability Testing
NCT05938270 A Study to Investigate the Biological Effects of Saruparib (AZD5305), Darolutamide, and in Combination in Men With Newly Diagnosed Prostate Cancer.
NCT02861573 Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)
NCT07214779 Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
NCT06568562 XL092 in Patients With Metastatic Castration-Resistant Prostate Cancer
NCT07382583 Development of a Shared Decision Tool to Facilitate Uptake of the Levonorgestrel-releasing Intrauterine System for the Primary Prevention of Endometrial Cancer
NCT05910294 A Study to Prevent and Improve Sexual Health Concerns for People With Breast Cancer
NCT04434040 Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)
NCT07120100 Transcranial Magnetic Stimulation for Chemotherapy-Induced Peripheral Neuropathy in Breast and Gynecologic Cancer Survivors
NCT07386444 Inspiratory Muscle Training for Breast Cancer Patients on Chemotherapy
NCT04291612 Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease
NCT06457919 A Study of Tinengotinib (TT-00420) in Combination With Standard Treatments in People With Prostate Cancer
NCT05941507 A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors
NCT05315700 Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration
NCT05873192 Presurgical Phase II Study of Talazoparib in Combination With Enzalutamide in Prostate Cancer
NCT06562192 Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
NCT06568692 A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer
NCT01174121 Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer
NCT05013216 Mutant KRAS -Targeted Long Peptide Vaccine for Patients at High Risk of Developing Pancreatic Cancer
NCT06525766 Adaptive Therapy With Capecitabine for Treatment of Metastatic ER Positive, HER2 Negative Breast Cancer
NCT06511141 Sacral Neuromodulation for Male Overactive Bladder (MOAB)
NCT06820463 A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer
NCT07252232 Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
NCT06813898 An Investigational Scan (rhPSMA-7.3 PET/CT) for Detecting Biochemically Recurrent Prostate Cancer, ENLIGHTEN Trial
NCT07228832 Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
NCT04893109 ATEMPT 2.0: Adjuvant T-DM1 vs TH
NCT06067503 Biomarkers to Detect Endocrine Therapy Resistance
NCT03620786 HIFU for Focal Ablation of Prostate Tissue: An Observational Study
NCT06374459 Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis
NCT02775461 Pancreas Registry and High Risk Registry
NCT06492616 A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
NCT04606914 Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant Chemotherapy With Advanced-Stage Ovarian, Fallopian Tube or Primary Peritoneal Cancer
NCT02333604 Cancer Experience Registry (CER) for Cancer Patients and Caregivers
NCT07259304 Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors
NCT06600906 Hyperpolarized 13C MRI to Predict Response in Pancreatic Cancer
NCT06682793 A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
NCT05412225 A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer
NCT06963905 Saci Nivo Rela for TNBC
NCT03842943 Neoadjuvant Combination Immunotherapy for Stage III Melanoma
NCT06270043 Focal Therapy for Localized Prostate Cancer
NCT04429542 Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
NCT04222413 Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors
NCT05652686 A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)
NCT06888921 A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer
NCT04251052 A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
NCT07209436 Impact of Pectoral Versus Paravertebral Blocks on Pain and Physical Well-Being in Implant-Based Breast Reconstruction
NCT06295744 Outcomes and Cosmesis With Whole Breast Irradiation and Boost
NCT07121244 A Phase 1 Study of 68Ga-R11228 and 177Lu-R11228 in Breast Cancer
NCT03054584 Genetic Basis of Melanocytic Nevi
NCT05789433 Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer
NCT07313306 Feasibility of Symptom Management for Patients With Metastatic Breast Cancer to Increase Exercise
NCT06605404 Pan-tumor MRD Study
NCT06464107 Endometrial Cell Collection With the PadKit
NCT06566092 Study of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult Participants
NCT07060807 A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
NCT07055165 Connect2Care: Prostate Cancer Education and Screenings for African American Men
NCT05086692 A Beta-only IL-2 ImmunoTherapY Study
NCT05053230 A Study Evaluating the Integrative Medicine at Home (IM@HOME) Program in People With Cancer
NCT06500481 Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial
NCT00949819 Active Surveillance for Cancer of the Prostate (ASCaP)
NCT07285057 Diagnostic Utility of rhPSMA-7.3 (18F) PET/CT in Men With Prostate Cancer on Active Surveillance
NCT01834001 Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy
NCT06044857 PSMA PET Response Guided SabR in High Risk Pca
NCT06055439 A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy
NCT05056077 Improving Nutrition and Physical Activity for Cancer Survivors (Tools To Be Fit)
NCT07145177 177Lu-PSMA-617 With Liver Directed Therapy in Metastatic Castration Resistant Prostate Cancer
NCT06518057 Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer
NCT06989112 DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
NCT04778449 Quality of Life, Lifestyle, and Psychosocial Factors in Patients With Melanoma
NCT05074290 Pharmacokinetics and Safety of Epidiferphane and Taxanes in Breast Cancer Patients
NCT06904313 Ultralow Dose PET Imaging for PSMA Expression
NCT04038619 Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients
NCT05297734 Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer
NCT05824975 A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
NCT04970056 Pancreatic Cancer Early Detection Consortium
NCT05219695 Medical Imaging and Thermal Treatment for Breast Tumors Using Harmonic Motion Imaging (HMI)
NCT06906341 Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers
NCT06879041 A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer
NCT07160439 Evaluating Digital Micro-Interventions to Reduce Distress and Increase Wellbeing in Breast Cancer Survivors
NCT05803941 Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer
NCT06440005 A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
NCT06593431 Extending Outcomes for Pancreas Cancer Patients With Nominal Oligometastatic Disease (EXPAND): A Randomized Phase III Trial
NCT05950945 Trastuzumab Deruxtecan (T-DXd) in Patients Who Have Hormone Receptor-negative and Hormone Receptor-positive HER2-low or HER2 IHC 0 Metastatic Breast Cancer
NCT02302742 Triple Negative Breast Cancer and Germline Hereditary Breast and Ovarian Cancer Mutation Carrier Registry
NCT04265872 Bortezomib Followed by Pembrolizumab and Cisplatin in metTNBC
NCT06989437 A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
NCT05770531 Circulating Tumor DNA to Guide Changes in Standard of Care Chemotherapy
NCT03127631 A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients
NCT07205822 A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0 Breast Cancer
NCT07317505 A Phase 1 Study of JMT108 in Participants With Advanced Solid Tumors
NCT06751329 A Study of DM002 in Patients With Advanced Solid Tumors
NCT05685602 CA-4948 Added to Standard Chemotherapy to Treat Metastatic or Unresectable Pancreatic Cancer
NCT06995053 Computed Tomography-Guided Stereotactic Body Radiation Therapy With Intrafraction Motion Monitoring for the Treatment of Localized Prostate Cancer, ILLUSION Trial
NCT05396872 Patient Decision-making About Precision Oncology in Veterans With Advanced Prostate Cancer
NCT07080242 Evaluating BL-M14D1 in Subjects With Locally Advanced or Metastatic Small Cell Lung Cancer and Neuroendocrine Tumors
NCT06318897 Open-label, Single Center, Single-arm, Phase 2 Study of Neoadjuvant Pembrolizumab in Combination With Carboplatin and Paclitaxel in Patients With Stage 1 cT1b-T1cN0M0 Triple Negative Breast Cancer
NCT02843945 Initial Feasibility Study to Treat Borderline Resectable Pancreatic Cancer With a Planar LDR Source
NCT04722341 Time-Restricted Eating and Cancer: Clinical Outcomes, Mechanisms, and Moderators
NCT01521741 Prospective Screening for Breast Cancer-related Lymphedema
NCT06378866 Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial
NCT04421820 BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours
NCT05253651 A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
NCT02594202 Care of the Prostate Cancer Patient and Prospective Procurement of Prostate Cancer Tissue
NCT04965064 Trial of Neratinib Plus Capecitabine in Subjects With HER2-Negative Metastatic Breast Cancer With Brain Metastases and Abnormally Active HER2 Signaling
NCT06400563 MRg-NIRS Imaging System Breast Cancer Trial
NCT06975293 STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers
NCT06745804 Study of 68Ga-R10602
NCT03833921 Evaluation of Response to Abiraterone/Prednisone by Race/Ethnicity and Other Factors in Metastatic Hormone Naive Prostate Cancer
NCT06960798 Characterizing the Genomic Landscape of Prostate Cancer in Native American Populations (NAT-Geno)
NCT06771544 Metronomic Cyclophosphamide With Pembrolizumab in Checkpoint Inhibitor Refractory Melanoma
NCT06220214 Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer
NCT05645471 Together After Cancer
NCT03936478 Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer
NCT04158635 Gemcitabine, Nab-Paclitaxel, and Bosentan for the Treatment of Unresectable Pancreatic Cancer
NCT05766891 Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer Surgery
NCT04363164 Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression
NCT07011576 A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (mCRC)
NCT06992258 A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer
NCT03753243 Neoadjuvant Pembrolizumab Plus Androgen Axis Blockade Prior to Prostatectomy for High Risk Localized Prostate Cancer
NCT05512208 A Phase 2 Study of Avutometinib (VS-6766) Plus Defactinib
NCT06586515 MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
NCT06946225 ACTengine® IMA203 Combined With mRNA-4203
NCT05691504 Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers
NCT06205316 SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate Adenocarcinoma
NCT07503808 A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types
NCT05256225 Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma
NCT05610735 Combination Therapy for Recurrent Ovarian Cancer
NCT07325721 Hypofractionated Radiotherapy With a Focal Microboost for High-Risk and Locally Advanced Prostate Cancer
NCT04841148 Avelumab or Hydroxychloroquine with or Without Palbociclib to Eliminate Dormant Breast Cancer
NCT05241236 MRI/Ultrasound Fusion Guided Laser Ablation of Prostate Cancer
NCT07458347 A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation
NCT04022616 Myeloid-Derived Suppressor Cell Function in Breast Cancer Patients
NCT07432633 [18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications
NCT05799248 Role of rhPSMA-7.3 PET/CT Imaging in Men With High-Risk Prostate Cancer Following Conventional Imaging and Associated Changes in Medical Management
NCT04594187 Nodal Radiation Therapy for Sentinel Lymph Node Positive Melanoma
NCT05805436 Preop Laxatives in Robotic Urologic Surgery
NCT04646434 Brain and Pelvic Floor Muscle Activity of Patients Who Had or Are Undergoing Robot-Assisted Radical Prostatectomy
NCT06890338 A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
NCT04983875 Mammography and Breast Arterial Calcification: An Information-Sharing Trial
NCT06085833 ARTIDIS Nanomechanical Generated Measurements for Early Breast Lesions
NCT07102381 A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
NCT07090499 A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
NCT01915225 Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer
NCT06405828 Enhancing Access to Supportive Services for Women of Color With Metastatic Breast Cancer
NCT06746428 Activity Coaching During Pelvic Radiation Therapy
NCT06517212 Tirzepatide Weight Loss for MRD+ Early Breast Cancer
NCT06756932 BGB-21447 (Bcl-2 Inhibitor) Combinations for Adults With Hormone-Receptor Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Metastatic Breast Cancer
NCT07222436 Circulating Tumor DNA in High Risk Localized Prostate Cancer
NCT06253871 A Phase 1/1b Study of IAM1363 in HER2 Cancers
NCT05669430 A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies
NCT03606967 Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer
NCT07225036 Promoting Immunotherapy Efficacy With Low-Dose Liver RT
NCT05472792 Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy
NCT07235293 A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.
NCT05612100 Endocrine Therapy-Induced Alopecia in Postmenopausal and Premenopausal Female Breast Cancer Patients
NCT07111507 A Study of Tarlatamab for People With Prostate Cancer
NCT04603209 Registry for Intra-Operative Radiotherapy During Breast Conserving Surgery in Patients With Early Stage Breast Cancer
NCT06691984 Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With Progressive Metastatic Castration-Resistant Prostate Cancer (XALute)
NCT03526835 A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
NCT05998135 Repurposing Atovaquone for the Treatment of Platinum-Resistant Ovarian Cancer
NCT05037825 The Gut Microbiome and Immune Checkpoint Inhibitor Therapy in Solid Tumors
NCT06827613 A Study of Invikafusp Alfa (STAR0602), a Selective T Cell Receptor (TCR)-Targeting, Bifunctional Antibody-fusion Molecule, in Combination With Sacituzumab Govitecan in Participants With Advanced Solid Tumors
NCT06610097 TNBC Gut Microbiota During Neoadjuvant Treatment
NCT07203482 Clinical Outcomes in Prostate Cancer Patients Undergoing HIFU Ablation
NCT06353997 Neoadjuvant INBRX-106 in Combination With Pembrolizumab for Stage II/III TNBC Patients
NCT06503146 18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection
NCT06079346 A Study of OT-101 With mFOLFIRINOX in Patients With Advanced and Unresectable or Metastatic Pancreatic Cancer
NCT07033689 Feasibility Study of Suizenji, in Patients With Unresectable Pancreatic Ductal Adenocarcinoma (SUNRISE-II)
NCT06925724 A Study of Ivonescimab in People With Endometrial and Cervical Cancers
NCT06123988 Prolonged Overnight Fasting and/or Exercise on Fatigue and Other Patient Reported Outcomes in Women With Hormone Receptor Positive Advanced Breast Cancer
NCT04234386 GammaPod Dose Escalation Radiation for Early Stage Breast Cancer
NCT02945579 Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy
NCT05755269 Adding a Genetic Risk Evaluation to Standard Breast Cancer Risk Assessment for African American and Hispanic Women
NCT05136196 BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study
NCT02706561 Helping Men Adhere to Sexual Rehabilitation Following Prostate Cancer Surgery
NCT05469269 Cleveland African American Prostate Cancer Project
NCT06202820 CV CARE: CardioVascular Care in PC Patients
NCT01788839 Longitudinal Sexual and Reproductive Health Study of Women With Breast Cancer and Lymphoma
NCT03643861 RAD 1802: Pilot Trial of Five Fraction Stereotactic Body Radiotherapy for Early Stage Breast Cancer Patients Eligible for Post-Operative Accelerated Partial Breast Irradiation (APBI)
NCT06291324 WATD and Cancer-Related Fatigue: A Study For Patients Undergoing Anti-Cancer Treatment
NCT02064673 Adjuvant Curcumin to Assess Recurrence Free Survival in Patients Who Have Had a Radical Prostatectomy
NCT06807437 Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula
NCT05001477 Customized TULSA-PRO Ablation Registry
NCT05557877 Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer
NCT04872166 A Study of BTX-A51 in People With Advanced Solid Tumor and Breast Cancer
NCT05045066 Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients
NCT06388122 DiviTum®TKa: A Biomarker Assay for Efficacy in HR+ Metastatic Breast Cancer Patients
NCT06435429 A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer
NCT06623396 A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer
NCT06545331 Study of XB010 in Subjects With Solid Tumors
NCT06635005 A Low-Insulinemic Dietary Intervention to Reduce Breast Cancer Risk in High-Risk Women
NCT03802851 HoLEP Prior to Radiation Therapy for Patients With LUTS/Retention and Concurrent Prostate Cancer
NCT02926729 Real-Time Assessment Of Breast Cancer Lumpectomy Specimen Margins With Nonlinear Microscopy
NCT06651632 WATER IV Prostate Cancer
NCT05325632 Study of HER2 Directed Dendritic Cell (DC1) Vaccine + Weekly Paclitaxel, Trastuzumab & Pertuzumab
NCT06580314 Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
NCT06974604 Preventing Dato-DXd Associated Stomatitis With Dexamethasone Mouthwash, TROPION-DM
NCT07360314 Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors
NCT04852887 De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
NCT04512144 Mindfulness in Endometrial and Cervical Cancer
NCT07124611 A Brief Psychological Intervention to Improve Emotional Well-Being During Neoadjuvant Therapy for Pancreatic Cancer
NCT06475937 A Study of DM001 in Patients With Advanced Solid Tumors
NCT06479239 Study of EGFRBi Armed Fresh PBMC in Metastatic or Unresectable Pancreatic Cancer
NCT05804370 Gleolan for Visualization of Newly Diagnosed or Recurrent Ovarian Cancer (OVA-302)
NCT07075731 Cervical and Endometrial Cancer Screening in Patients Seeking Gender-Affirming Hysterectomy
NCT06236139 Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer
NCT06158139 Autologous CAR-T Cells Targeting B7-H3 in PDAC
NCT06972628 Treatment of Patients With Progressive mCRPC With 177Lu-PSMA-617
NCT06022822 Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial
NCT00005095 Specimen and Data Study for Ovarian Cancer Early Detection and Prevention
NCT06111781 The SUGAR Study; SBRT and Relugolix) for Prostate Cancer
NCT02595957 Genomic Services Research Program
NCT06875128 Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant Disease
NCT05620329 UNC Pleural Fluid Registry
NCT07120945 Hugo™ Robotic-Assisted Surgery (RAS) System in Gynecological Subjects (Embrace Gynecology)
NCT04633239 Testing the Addition of Abemaciclib to Olaparib for Women With Recurrent Ovarian Cancer
NCT07144228 Validation of a Platelet Proteomic Assay for Diagnosing and Monitoring Prostate Cancer
NCT05952453 Newly Diagnosed Stage III/IV Ovarian Cancer, Neoadjuvant Carbo/Taxol/Pembro, Maintenance Olaparib/Pembro
NCT03659448 Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer
NCT03564340 Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers
NCT06544655 A Study of BMS-986484 Alone and Combination Therapy in Participants With Advanced Solid Tumors
NCT04969315 TT-10 (PORT-6) and TT-4 (PORT-7) as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors
NCT04526587 Biomarkers and Clinical Features of Metastatic Breast Cancer in Patients Treated With CDK4/6 Inhibitors
NCT06730347 A Study of Lorigerlimab in Participants With Advanced Solid Tumors
NCT05964504 Improving Survival for Metastatic Lobular Breast Cancer (PLUMB Registry)
NCT06305598 Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer
NCT06999798 An Optimized Ultrasound Twinkling Marker for the Imaging of Lymph Nodes in Patients With Clinically Node-Positive Breast Cancer, The UTMOST2 Trial
NCT05126290 CTNNA1 Familial Expansion Study
NCT02016248 SBRT Boost for Unfavorable Prostate Cancer'
NCT05727904 Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.
NCT05610852 Single-Port Transvesical Partial Prostatectomy Versus High Intensity Focused Ultrasound
NCT06880055 Shield Post-Approval Study Protocol
NCT06610825 Castrate Resistant Prostate Cancer Enhertu Therapy
NCT05445778 Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer
NCT06603597 HER2-positive Breast Cancer Registry
NCT06494150 Nab-Sirolimus and Endocrine Therapy in Recurrent Low Grade Serous Ovarian Cancer (NARETO)
NCT07318558 A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)
NCT06557148 A Study Comparing Cancer Imaging Approaches in People With Lobular Breast Cancer
NCT06111313 The University of Miami Adapt (UAdapt) Trial
NCT05534438 A Study on Adding Precisely Targeted Radiation Therapy (Stereotactic Body Radiation Therapy) to the Usual Treatment Approach (Drug Therapy) in People With Breast Cancer
NCT05754749 Comparison of CE-DBT and MRI in Patients With Known Breast Lesions
NCT05780814 The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer
NCT06881992 A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism
NCT05877599 A Study of NT-175 in Adult Subjects With Unresectable, Advanced, and/or Metastatic Solid Tumors That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
NCT07009093 Utility of a Mobile Application for Young Women With Breast Cancer
NCT06726148 Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and Other Advanced Solid Tumors
NCT04048278 Lidocaine Infusion in Pancreatic Cancer
NCT05581004 A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors
NCT07070726 UNTOLD Ovarian Cancer Unmet Needs Survey
NCT04073706 Sentinel Node Biopsy in Endometrial Cancer
NCT06757634 Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)
NCT06064149 The CArdiovascular Risk Evaluation in Men With Prostate Cancer Study (CARE-PC) Pilot Feasibility Study
NCT05978128 Utilizing Advocates and Supporters to Increase Lung Cancer Screening Rates in Eligible Participants
NCT03422198 Short Course Vaginal Cuff Brachytherapy in Treating Participants With Stage I-II Endometrial Cancer
NCT02997293 Impact of the Enhanced Recovery After Surgery System for Colorectal Surgery
NCT03878849 Investigation of the Anti-tumor Effect of 2X-121 in Patients With Recurrent, Advanced Ovarian Cancer
NCT07107334 A Study to Estimate Early Clinical Efficacy Signals of GLP-1 Agonist Administration in Conjunction With Levonorgestrel Intrauterine Device in Obese Patients With Endometrioid Intraepithelial Neoplasia
NCT06568016 A Clinic-wide Intervention (Primary Care-GI Connect) for Improving Rates of Colonoscopy After Abnormal Fecal Immunochemical Test Result in Patients at Federally Qualified Health Centers
NCT05967533 The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint Inhibitors
NCT05464082 Functional Precision Oncology to Predict, Prevent, and Treat Early Metastatic Recurrence of TNBC
NCT06758102 Dance Study for Post-surgical Pain in Breast Cancer Survivors
NCT06085742 BRE-08 Phase II Study of CMC Regimen for Early Stage Breast Cancer
NCT03463954 Confirmatory Clinical Evaluation of Novilase® Laser Therapy for Focal Destruction of Malignant Breast Tumors
NCT06910670 Implementing a Randomized Control Trial to Test the Expanded Web-based Decision Aid
NCT05559879 Cabozantinib and Dostarlimab in Recurrent Gynecologic Carcinosarcoma
NCT06500169 Golf Recreational Exercise for Enhanced Survivorship in Prostate Cancer Survivors
NCT05684367 Exercise to ReGain Stamina and Energy (The EXERGISE Study)
NCT06112314 IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)
NCT02279004 A Prospective Study of Plasma Genotyping as a Noninvasive Biomarker for Genotype-directed Cancer Care
NCT05013255 Pioglitazone Therapy Targeting Fatigue in Breast Cancer
NCT01042548 Proteomics and Radiomics Research of Breast Cancer Markers in Tissue, Interstitial Fluid and Serum
NCT07020806 [68Ga]Ga DOTA-5G as a Diagnostic Imaging Agent for Metastatic/Advanced Invasive Lobular Breast Cancer (LBC)
NCT05323409 Improving Comprehensive Care of Cancer Patients
NCT06377852 The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study
NCT05334732 Improving Communication and Adherence in Black Breast Cancer Survivors (Sisters Informing Sisters)
NCT04516447 A Study of ZN-c3 in Patients With Ovarian Cancer
NCT06483555 Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel
NCT05655312 MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma
NCT07220967 A Study of Antibiotic Delivery to Prevent Infection After Breast Tissue Expander Placement
NCT05464667 Preoperative Irradiation for Stage I Breast Cancer
NCT07030907 A Study to Evaluate the Safety and Efficacy of OPB-101 in Platinum-resistant Ovarian Cancer
NCT05977036 BettER: Biomarker Driven Early Therapeutic Selection in Patients With HR+ HER2- Metastatic or Unresectable Breast Cancer
NCT06330064 A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)
NCT07213609 A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors
NCT04473833 Transvaginal Ultrasonography as a Screening Method for Ovarian Cancer
NCT07319871 A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer
NCT04990921 Study of Palliative Radiation Combined with Pembrolizumab in Unresectable Metastatic Stage IV Breast Cancer
NCT06970847 64Cu-SAR-bisPSMA Positron Emission Tomography: A Phase 3 Study of Participants With Biochemical Recurrence of Prostate Cancer
NCT05766371 Pembrolizumab Plus 177Lu-PSMA-617 in Patients With Castration Resistant Prostate Cancer
NCT05458544 [Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application
NCT02012699 Integrated Cancer Repository for Cancer Research
NCT06526299 Low PSMA SUV Boost (LPS-Boost): Intensified 177Lu-PSMA-617 Treatment for Patients With Metastatic Castrate-Resistant Prostate Cancer With Low PSMA Expressing Disease
NCT06855706 An Automated Personalized Physical Activity Intervention to Improve Immune Function and Clinical Outcomes in Stage II-IV Ovarian, Primary Peritoneal or Fallopian Tube Cancer and Newly Diagnosed Endometrial Cancer, Life on the Go 3 Study
NCT01050504 Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer
NCT05216432 First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer
NCT06618287 A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
NCT07436078 Culturally Adapting an Intervention to Increase Genetic Testing in African American Cancer Survivors
NCT05797168 Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors
NCT07450859 A Study of BT5528 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)
NCT04318717 Pembrolizumab and Hypofractionated Radiation Therapy for the Treatment of Mucosal Melanoma
NCT07308717 Gabapentin And Breast Surgery Decision Architecture Randomization Trial (GABS-DART) Protocol
NCT07087691 Efficacy of OneMark Device in Identifying Breast Cancer for Surgery and Surveillance
NCT03866382 Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
NCT04567420 DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)
NCT07214610 Integrating Biological, Clinical, and Behavioral Factors to Improve Breast Cancer Outcomes - Carolina Breast Cancer Study
NCT06931340 Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
NCT05128890 Evaluation of Resection Techniques for Pancreatic Tumors
NCT05913388 GB1211 and Pembrolizumab Versus Pembrolizumab and Placebo in Patients With Metastatic Melanoma and Head and Neck Squamous Cell Carcinoma
NCT05704062 Quantitative MRI Assessment of Breast Cancer Therapy Response
NCT06185205 ASHBY: Accelerated Super-Hypofractionated Breast Brachytherapy
NCT06635980 Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast Cancer
NCT05169970 A Study of Stereotactic Body Radiation Therapy (SBRT) Without Androgen Deprivation Therapy (ADT) in People With Unfavorable Intermediate-Risk Prostate Cancer
NCT06856694 RCT of NLP-Based Feedback for Improving SDM in Men With Localized Prostate Cancer
NCT04473794 Diagnostic Strategies, Risk Assessment and Progression of Pancreatic Cysts
NCT06705803 Prostate Ablation Registry and Database for Information, Surveillance, and Evaluation (PARADISE)
NCT04857502 99mTc-PSMA-I&S Biodistribution in Patients With Prostate Cancer
NCT07130903 Amplitude-Modulated Radiofrequency Electromagnetic Fields (AM RF EMF) in Combination With Fruquintinib in Refractory Metastatic Colorectal Cancer
NCT05465941 PLX038 for Treatment of Metastatic Platinum-resistant Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
NCT05984888 Pilot Study of a MIND Diet Intervention in Women Undergoing Active Treatment for Breast Cancer
NCT07018869 Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors
NCT06172127 PHESGO Maintenance After T-DXd Short Induction for HER2+ Unresectable Locally Recurrent or Metastatic Breast Cancer
NCT06228053 Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancer
NCT06347705 A Study of 2141-V11 in Combination With Standard Treatments in People With Prostate Cancer
NCT06695845 A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
NCT07044310 5-strain Probiotic Formulation in HR-positive Breast Cancer Receiving Aromatase Inhibitor to Prevent Bone Loss
NCT06441890 BRE-10: Biomarker Optimization of Neoadjuvant Therapy in Breast Cancer
NCT05879913 ASCVD Management Using CCTA in Prostate Cancer Patients on ADT
NCT06677190 Belzutifan in Recurrent Clear Cell Carcinoma of Gynecologic Origin
NCT05076760 MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors
NCT04174742 Self Reported Pain in Women While Undergoing Treatment for Non-metastatic Breast Cancer
NCT06428396 Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)
NCT03322891 Improving Health Literacy in African-American Prostate Cancer Patients
NCT07046923 A Study of LY4175408 in Participants With Advanced Cancer
NCT03704662 Preoperative Fractionated Radiation Therapy Versus Stereotactic Body Radiation Therapy for Resectable or Borderline Resectable, or Locally Advanced Type A Pancreatic Adenocarcinoma
NCT05040360 Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors
NCT05373823 MySmartSkin Online Skin Self-exam Intervention for Melanoma Survivors
NCT06499870 Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial
NCT07280312 Ultrasound Microvessel Imaging for the Evaluation of Ovarian and Adnexal Lesions
NCT06612281 Evaluation of Gixam's Performance in a FIT Negative Population
NCT06040541 Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors
NCT06666439 Longitudinal Tumor Burden Quantification Using Circulating Tumor DNA in Metastatic Lobular Breast Cancer
NCT06099769 A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer
NCT06953245 Collecting Patient-Reported Experiences With Radiation Dermatitis in Breast Cancer Patients Undergoing Radiotherapy
NCT05882253 Prostate Cancer IMAGing IN Early Detection (IMAGINED Trial)
NCT03645928 Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors
NCT04904757 Contrast-enhanced Spectral Mammography (CESM) Breast Cancer Screening
NCT06070012 Tebentafusp in HLA-A*0201 Positive Previously Untreated Metastatic Uveal Melanoma
NCT04368702 CONFIRM: Magnetic Resonance Guided Radiation Therapy
NCT06399757 A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors
NCT07220512 The Better, Harder, Faster, Stronger Study
NCT06462183 Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)
NCT05238922 Study of INCB123667 in Subjects With Advanced Solid Tumors
NCT00898131 Collecting Tissue Samples for Future Research From Women Undergoing Surgery for Breast Cancer
NCT04752826 BI-1808 as a Single Agent and With Pembrolizumab (KEYTRUDA® ) in Treatment of Advanced Malignancies(Keynote-D20)
NCT07219147 177^Lu-PSMA-617 in Combination With Sipuleucel-T for the Treatment of Metastatic Castration-Resistant Prostate Cancer
NCT06445738 Post-operative Radiotherapy Omission in Selected Patients With Early Breast Cancer Trial International VErsion (PROSPECTIVE)
NCT07447050 Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial
NCT06827704 Physical Activity Targeting Metabolic Syndrome for Prevention of Breast Cancer in SAI Women
NCT07293585 Vascular Optimized Radiotherapy Tuned to Critical Structures for Erectile Function Using High-Precision X-Ray Treatment
NCT06401889 Enhancing Skin Appearance and Quality of Life in Breast Cancer Survivors on Aromatase Inhibitor Therapy
NCT05804318 Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer
NCT02381990 MRI/Ultrasound Fusion Guided Prostate Cryotherapy
NCT05020574 Microbiome and Association With Implant Infections
NCT05146297 Diversity and Inclusion in Research Underpinning Prevention and Therapy Trials
NCT03460977 A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma
NCT06934239 A Trial Comparing Screening Mammography With and Without Assistance From Artificial Intelligence for Breast Cancer Detection and Recall Rates in Adult Patients
NCT05805371 PSCA-Targeting CAR-T Cells Plus or Minus Radiation for the Treatment of Patients With PSCA+ Metastatic Castration-Resistant Prostate Cancer
NCT04115163 Biologically Optimized Infusion Schedule of Gemcitabine and Nab-Paclitaxel for the Treatment of Metastatic Pancreatic Cancer
NCT05576896 Hydroxychloroquine in Combination With Encorafenib and Cetuximab or Panitumumab in the Treatment of Metastatic BRAF-mutated Colorectal Cancer Refractory
NCT05365581 A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
NCT07479381 Colorectal Lesion Evaluation and Appropriate Resolution (CLEAR) Study
NCT05376592 Assoc. of Genomic Polymorphisms With Cancer Cachexia in Subjects With Panc Adenocarcinoma
NCT05996107 Study of Ribociclib Administered Concurrently With Postoperative Radiation Therapy in Patients With High-Risk, HR+/HER2- Breast Cancer
NCT04049214 Perioperative Mindfulness Proposal
NCT06993844 Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors
NCT05264974 Novel RNA-lipid Particle (RNA-LP) Vaccine for Anti-PD-1 Antibody Therapy Sensitization
NCT02863172 Molecular Basis for Variations in Hereditary Colorectal Cancer Syndromes
NCT07223047 A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies
NCT06675643 Digital Remote Monitoring of Immune Checkpoint Inhibitor Therapy Induced Toxicity Using the Vigilant App
NCT06265285 Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program
NCT06092892 IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases
NCT06876714 ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
NCT05280314 Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors
NCT04816006 Breast Cancer, Reasoning, and Activity Intervention
NCT07216248 Optimal PSA Triggered Individual Management of Androgen Sensitive Prostate Cancer
NCT00923221 Collection of Blood From Patients With Prostate Cancer
NCT06423326 Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer
NCT06778863 A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
NCT06428409 A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
NCT06105749 Biennial CEM in Women With a Personal History of Breast Cancer
NCT05704647 Phase II Study of Nivolumab in Combination With Relatlimab in Patients With Active Melanoma Brain Metastases
NCT03863457 [18F] F-GLN by PET/CT in Breast Cancer
NCT07062016 Molecular and ctDNA Characterization of High-Risk Endometrial Cancer
NCT06559540 Ultra-Hypofractionated vs. Hypofractionated Radiation for Node-Positive Breast Cancer
NCT07040514 24GUT540 : Meeting of Breast Cancer Patients and Pathologists
NCT06790693 A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
NCT06806930 Predicting Response to Neoadjuvant Endocrine Therapy (Neo-PREDICT)
NCT05961982 Evaluation of Endoscopic Ultrasound-Guided Radiofrequency Ablation for the Management of Pancreatic Tumors, ERASE Study
NCT05994482 Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study
NCT05113537 Abemaciclib Before 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer
NCT05625529 ExoLuminate Study for Early Detection of Pancreatic Cancer
NCT05608694 MRI Screening in Men at High Risk of Developing Prostate Cancer
NCT06349642 Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform
NCT06435351 Personalized Dendritic Cell Vaccine Pilot for High Risk TNBC After Neoadjuvant Therapy
NCT07470853 A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.
NCT06887348 A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3
NCT05868226 PRE-I-SPY Phase I/Ib Oncology Platform Program
NCT07023887 Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning
NCT07144826 Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy
NCT06576115 Gemcitabine, Nab-paclitaxel Plus the TheraBionic P1 (an Amplitude-Modulated Radiofrequency Electromagnetic Fields) Device to Treat Metastatic Pancreatic Cancer
NCT06957535 Community-led Navigation to Address Disparities in Mammography Among Native American Women
NCT04104776 A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
NCT03861676 Image-guided Focal Brachytherapy Utilizing Combined 18F-DCFPyl PET/CT
NCT07427043 Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES)
NCT06534125 Acutherapy to Prevent Aromatase Inhibitor-Associated Arthralgias in Non-Hispanic Black Postmenopausal Women With Early-Stage Breast Cancer
NCT06238921 Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases
NCT05646316 Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer
NCT07318805 A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors
NCT05903131 Uterine Preservation Via Lifestyle Transformation
NCT06247995 A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.
NCT05056857 Neutrophil Extracellular Traps Formation in Breast Cancer Patients Taking Tamoxifen
NCT07189403 A Study of DS9051b in Participants With Advanced or Metastatic Adrenocortical Carcinoma and Metastatic Castration-resistant Prostate Cancer
NCT06239194 Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
NCT06030622 Phase 2A Pilot C3 Trial of Recurrent/Refractory Metastatic Advanced Pancreatic Cancer
NCT05899361 A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of Interest
NCT05693766 Gene Signatures to Guide HR+MBC Therapy in a Diverse Cohort
NCT07184957 Prospective Database of Clinical Outcomes Following Cryotherapy for Ablation of Clinically Localized Prostate Cancer
NCT02610439 Whole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Peripheral Neuropathy Receiving Paclitaxel for Breast Cancer
NCT05726292 A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer
NCT07189871 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors
NCT07244341 A Study of Valemetostat (DS-3201b) in Combination With Darolutamide in Metastatic Castration Resistant Prostate Cancer (mCRPC)
NCT07215000 Cleansing Options in Out-Patient Setting to Improve Tolerance (COOP SIT) Trial
NCT05095207 Abemaciclib in Combination With Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer
NCT04485013 TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
NCT06445062 Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
NCT06428682 Role of TXA in Patients Undergoing Breast Free Flap Reconstruction
NCT05080946 Using Aspirin to Improve Immunological Features of Ovarian Tumors
NCT07054346 Comparison of 177Lu-PSMA-617 and 225Ac-PSMA-617
NCT06922591 Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients
NCT00539162 Use of the CA 125 Algorithm for the Early Detection of Ovarian Cancer in Low Risk Women
NCT06548789 Neoadjuvant Immune Checkpoint Blockade + a Prebiotic Food-enriched Dietary Intervention to Optimize Immune Response in Melanoma: NEO-PreFED
NCT04315233 Ribociclib&Belinostat In Patients w Metastatic Triple Neg Breast Cancer & Recurrent Ovarian Cancer w Response Prediction By Genomics
NCT07076485 Shortening Adjuvant Photon and Proton Irradiation (SAPPHIRe-II): A 4 Cohort, Randomized, Phase II Multi-center Trial Evaluating Shorter Schedules of Adjuvant Regional Nodal Irradiation Among Women and Men With Node-positive and High-risk Node-negative Invasive Breast Cancer
NCT06671730 Self-Determination Theory-informed Occupational Therapy Program to Increase Physical Activity Among Survivors of Breast Cancer
NCT07220863 Breast Mapping and Detection of Suspicious Breast Lesions Using Feminai
NCT06257693 Enzalutamide Implants (Enolen) in Patients With Prostate Cancer
NCT02620852 Women Informed to Screen Depending on Measures of Risk (Wisdom Study)
NCT06216249 Phase 2 Randomized Trial of Flexible Dosing Schedule of 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer (FLEX-MRT)
NCT07042581 A Study of Revaree Plus in People With Breast Cancer
NCT06782555 A Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab
NCT05071937 ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer
NCT05088798 Utility of 18FDOPA PET/MRI for Focal Hyperinsulinism
NCT03354416 Profiling of Radiological Factors in Treatment and Outcomes in Prostate Cancer
NCT06731998 Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
NCT06408298 HCQ in Resectable Localized Prostate Cancer
NCT06353321 Non-significant Risk (NSR) Study of [68Ga]-PSMA-11 (Illuccix) as a BgRT BioGuide on RefleXion X1
NCT06681233 Feasibility Study of CBCT for IGRT in Cancer Patients
NCT06943755 Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
NCT05846789 SOC Chemotherapy +/- Tocilizumab for Triple Negative and ER-low Breast Cancers
NCT07172282 INFINITIVE: ImmuNotherapy For PatIeNts wIth colorecTal LIVer MEtastases
NCT07361562 A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors
NCT05056818 Comparison of Synthetic Mammography Versus Full-Field Digital Mammography in Image Interpretation and Performance Metrics
NCT05568680 SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma
NCT07181473 A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of TJ101 in Patients With Advanced/Metastatic Solid Tumors
NCT05351424 AVI Didactic Experience for Latinx Patient Treatment Adherence and Non-English Speaker Trial Enrollment Study in Rad Onc
NCT06926920 A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer
NCT05704842 Evaluate Impact of Exercise Program on Fatigue in Breast Cancer During Chemotherapy
NCT07071896 A Prospective Study of Video-assisted Exercise Program for the Breast Cancer Survivors
NCT06788886 Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases
NCT06855277 Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
NCT04541381 The PhOCus Trial: Implementation of Pharmacogenomic Testing in Oncology Care
NCT04114136 Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies
NCT06062745 Pilot Study for Detection of PSMA-Low CRPC-NE Tumors With Fluciclovine PET/CT
NCT04861077 Monitoring Breast Cancer Immunotherapy Treatment With Advanced Positron Emission Tomography Magnetic Resonance Imaging (PET/MRI)
NCT05607095 A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, or Dedifferentiated Liposarcoma
NCT06580002 Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
NCT07237100 Mirdametinib in Patients With Advanced NF1-mutant Melanoma
NCT07193862 Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Colorectal Liver Metastasis
NCT07396766 Dissemination of BREASTChoice AIM1-B
NCT04636710 Refining Local-Regional Therapy for IBC
NCT04753359 Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer
NCT06984562 Adaptive Radiation for Locally Advanced Unresectable Pancreatic Cancer
NCT07294703 Factors Associated With Breast Cancer Risks and Outcomes
NCT06245889 PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC
NCT05123482 A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
NCT06151223 A Prospective Registry for Patients at High-Risk for Pancreatic Cancer
NCT07197723 Study of How People Make Decisions About Prostate Cancer Risk
NCT05394259 A Pilot Study to Assess the Clinical Utility of PYLARIFY PET-CT for Detecting Metastasis in Pancreatic Cancer, Hepatocellular Carcinoma and Breast Cancer
NCT06340568 A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer
NCT05687123 Testing the Addition of Sunitinib Malate to Lutetium Lu 177 Dotatate (Lutathera) in Pancreatic Neuroendocrine Tumors
NCT06582615 Food for Thought - A Nutrition Intervention for Women Undergoing Active Treatment for Triple Negative Breast Cancer
NCT06401421 EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)
NCT03467516 Adoptive Transfer of Tumor Infiltrating Lymphocytes for Metastatic Uveal Melanoma
NCT05190978 Randomized Feasibility Trial for Mesh in Pre-Pectoral Reconstruction
NCT04994067 Intra-Operative Radiation Registry
NCT07142967 Trial Evaluating the Safety and Efficacy Of MR-Linac-Guided Radiotherapy as Salvage Treatment After External Beam Radiotherapy Recurrence (TUMORNATOR II)
NCT05035836 A Phase 2 Single-Arm Open-Label Pilot Trial Evaluating Zanidatamab (ZW25) in Patients With Early Stage HER2/Neu Positive (HER2+) Breast Cancer (BC)
NCT05295407 Performance of Inherited Risk Assessment for Predicting Prostate Cancer From Prostate Biopsy
NCT07203378 Nurturing Exercise Routine for Greater Improvement in Zest and Energy on Enhertu
NCT07044583 SAVE Trial: SAfe Opioid Use Video Education
NCT05649072 Identifying Underserved Individuals inTexas With Hereditary Cancer Risk Using Mobile Mammography Units and Telegenetics.
NCT04175431 Prostate Specific Membrane Antigen (PSMA) or (FACBC) PET/CT Site-Directed Therapy for Treatment of Prostate Cancer, Flu-BLAST-PC Study
NCT06402331 FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC)
NCT07028853 This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
NCT07112053 A Vaccine (STEMVAC) With Standard Endocrine-Based Therapy or Chemotherapy for the Treatment of Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer
NCT06986083 A Study of Changes to Prostate Procedures
NCT06731894 Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors
NCT05231122 Pembrolizumab Combined With Bevacizumab With or Without Agonist Anti-CD40 CDX-1140 for the Treatment of Patients With Recurrent Ovarian Cancer
NCT06845319 Anthracycline-Free Neoadjuvant Chemoimmunotherapy for Triple Negative Breast Cancer Patients
NCT00353483 Effect of Neoadjuvant or Adjuvant Systemic Therapy on Breast Cancers, Bone Marrow Cancer Cells, and Circulating Cancer Cells
NCT07220239 Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome
NCT00899301 Collecting and Storing Tissue Samples From Women With or Without Breast Cancer
NCT02476786 Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score
NCT05112601 Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma
NCT03954431 High-Resolution Lower Dose Dedicated Breast Computed Tomography (CT)
NCT06075953 DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment
NCT05703178 Web-based Pain Coping Skills Training for Breast Cancer Survivors With AI-Associated Arthralgia
NCT05130606 CONTIGO - A Narrative Intervention to Enhance Genetic Counseling and Testing
NCT05309655 Cardiac Outcomes With Near-Complete Estrogen Deprivation
NCT05985655 Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors
NCT06040125 Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial
NCT04997096 Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy
NCT05654246 Susan G. Komen's ShareForCures
NCT07335224 Men With Prostate Cancer: Optimizing Wellness by Enhanced Relief From Hot Flashes With Acupuncture
NCT07254091 Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Pancreatic Cancer
NCT03175224 APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
NCT05464810 Letrozole With and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negative Breast Cancer
NCT00291096 High Risk Breast Clinic: Protocol for Women at Increased Risk for Developing Breast Cancer
NCT05784688 Study of TU2218 in Combination With KEYTRUDA®(Pembrolizumab) in Patients With Advanced Solid Tumors
NCT06112990 Creatine Supplementation and Resistance Training to Preserve Muscle Mass and Attenuate Cancer Progression
NCT06563388 Stereotactic Ablative Radiotherapy (SABR) for the Treatment of Patients With Metastatic Cancer, ID-COMET Trial
NCT07276386 Phase 2 Combination of Melphalan/HDS Via PHP + Tebentafusp in Treating Metastatic Uveal Melanoma
NCT07201376 Assessment of Skin Lesions Using a Tissue Oxygen Imager Based on Protoporphyrin IX (PPIX) Fluorescence. This is an Open-label, Non-randomized, Feasibility Study That Includes a One-time Application of an FDA Approved Medication Followed by Local Imaging for Benign Skin Growth and Lesions Clinically
NCT05870579 [177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer
NCT04796818 An Investigational Scan (Intravoxel Incoherent Motion Diffusion Weighted Imaging) for the Evaluation of Colorectal Cancer Liver Metastases Treatment Response
NCT03796559 Magseed Enabled Long-Term Localization of Axillary Lymph Nodes
NCT04915508 Extremely Hypofractionated Intensity Modulated Stereotactic Body Radiotherapy for the Treatment of Prostate Cancer With Rising PSA After Radical Prostatectomy
NCT05692024 COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER
NCT03572374 Talking to Employers and Medical Staff About Breast Cancer Treatment and Your Job
NCT06476808 A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.
NCT03460769 Evaluation of a Mixed Meal Test for Diagnosis and Characterization and Type 3c Diabetes Mellitus Secondary to Pancreatic Cancer and Chronic Pancreatitis (DETECT)
NCT06128551 Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
NCT04751396 Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
NCT05422794 Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer
NCT00991094 Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton Therapy
NCT05774951 A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy
NCT07186842 A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9
NCT05797831 Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer
NCT05398302 Image-Guided Biopsies to Identify Mechanisms of Resistance in Patients With Metastatic Castration Resistant Prostate Cancer Treated With 177Lu-PSMA Radioligand Therapy
NCT05053555 High Dose-Rate Brachytherapy for the Treatment of Both Primary and Secondary Unresectable Liver Malignancies
NCT05806515 Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation
NCT06136624 Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
NCT05377996 A Study of XMT-1660 in Participants With Solid Tumors
NCT05467891 Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer
NCT06959550 Phase II Study of Anti-PD-1/VEGF Bispecific Antibody Ivonescimab in Patients With Previously Treated Metastatic Colorectal Cancer
NCT06412510 Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT
NCT06534918 Precise Oncology Interventions in Nutrition and Training (OnPoint)
NCT07288359 Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors
NCT05413850 Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection
NCT04916990 Improving Care for Rural Patients With Solid Tumors
NCT04887935 Neoadjuvant SGLT2 Inhibition in Localized Prostate Cancer
NCT03474913 Upright MRI for Prostate Cancer Screening
NCT05053152 Testing the Addition of the Drug Relugolix to the Usual Radiation Therapy for Advanced-Stage Prostate Cancer, The NRG Promethean Study
NCT04474301 Well-Being and Health-Related Quality of Life in Melanoma Patients During COVID-19 Pandemic
NCT04003038 Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery
NCT06165302 Exercise in Prostate Cancer
NCT06888102 A Platform Study of Epigenetic Therapy Before Prostatectomy in Men With Prostate Cancer
NCT03906253 Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia
NCT06579417 ART-Pro: Clinical Trial Evaluating Biparametric MRI and Advanced, Quantitative Diffusion MRI for Detection of Prostate Cancer
NCT06594991 A Study of Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma
NCT05530655 A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer
NCT04768426 Serial Circulating Tumor DNA (ctDNA) Monitoring During Adjuvant Capecitabine in Early Triple-negative Breast Cancer
NCT06276491 Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors
NCT06507618 Pre-Operative Window of ET to Inform RT Decisions (POWER II)
NCT07162194 MRI-Based Machine Learning Approach Versus Radiologist MRI Reading for the Detection of Prostate Cancer, The PRIMER Trial
NCT05271318 Oncolytic Adenovirus Coding for TNFa and IL2 (TILT-123) With Pembrolizumab or Pembrolizumab (Phase 1a) and Pegylated Liposomal Doxorubicin (Phase 1b) as Treatment for Ovarian Cancer.
NCT06060613 Safety and Efficacy of OBX-115 in Advanced Solid Tumors
NCT06465069 A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
NCT06974110 Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors
NCT05946824 This Study is Evaluating a New Radiation Treatment Technique for Patients Who Have Had Prostate Cancer, Undergone Surgery for Cancer, and Then Have Evidence That Their Prostate Cancer Has Returned.
NCT03740256 Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors
NCT06047379 Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
NCT06004661 Study of Lutetium (177Lu) Vipivotide Tetraxetan in mCRPC Participants With Moderately and Severely Impaired and With Normal Renal Function
NCT04650256 Application of Chinese Herbal Complementary and Alternative Medicine (CAM) to Improve Human Health and to Further Botanical and Horticultural Sciences
NCT07069556 ColoSense Post-Approval Study
NCT03025256 Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease
NCT06515613 A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors
NCT04633252 A Phase I/II Study of PDS01ADC With Docetaxel and Abiraterone in Adults With Metastatic Castration Sensitive and PDS01ADC With Docetaxel in Castration Resistant Prostate Cancer
NCT06565052 The Impact of PReOPerative Exercise and NutritionaL Optimization on Perioperative Outcomes for Patients Undergoing Treatment for Rectal Cancer: The PROPEL Trial
NCT05774678 Trial Of PreoperAtive Radiation (TOPAz): A Randomized Trial Comparing Hypofractionated Versus Conventionally Fractionated Preoperative Radiation Followed by Mastectomy With Immediate Autologous Breast Reconstruction With Integrated Nanomechanical Biomarker Evaluation
NCT06369285 A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
NCT06865768 An Investigational Scan (18F-rhPSMA-7.3 PET-mpMRI) for Targeted Prostate Biopsy Using TRUS-MR Fusion Technique
NCT06887218 5-Fluorouracil/Leucovorin (5FU/LV) in Combination With Regorafenib in Patients With Metastatic Colorectal Cancer
NCT06385925 A Study of TSN1611 Treating Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation
NCT05979610 Using Reiki Therapy to Improve Symptoms Associated With Brachytherapy in Patients With Gynecological Malignancies
NCT07047872 A 3D-Printed External Breast Prosthesis for the Improvement of Patient-reported Outcomes Among Breast Cancer Patients That Underwent a Mastectomy Without Reconstruction
NCT06252545 Promoting CT Engagement for Pancreatic Cancer With App
NCT06651580 Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study
NCT04692675 Multiparametric Magnetic Resonance Imaging of the Prostate to Assess Disease Progression and Genomics in Patients Undergoing Active Surveillance for Prostate Cancer
NCT06149481 Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC)
NCT04511039 Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer
NCT06877572 Weight Loss Management in Endometrial Cancer Survivors
NCT05396612 Role of the Immune Environment in Response to Therapy in Breast Cancer
NCT06101277 Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG)
NCT05283330 Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors
NCT04543071 Chemo4METPANC Combination Chemokine Inhibitor, Immunotherapy, and Chemotherapy in Pancreatic Adenocarcinoma
NCT04683653 Study of Pelvic Hypofractionated Radiotherapy in Endometrial Cancer
NCT06763328 Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy
NCT06799065 First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer
NCT06586957 A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors
NCT05489211 Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
NCT06643767 Evaluation of the Bexa Breast Examination
NCT06411795 Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy
NCT05042687 Comparative Performance of Molecular Breast Imaging (MBI) to Magnetic Resonance Imaging (MRI) of the Breast in Identifying and Excluding Breast Carcinoma in Women at High Risk for Breast Cancer
NCT07270237 A Study of Multiparametric Ultrasound Imaging Methods
NCT05490472 JAB-2485 Activity in Adult Patients With Advanced Solid Tumors
NCT05452681 Piloting Y-AMBIENT: A Quality of Life Intervention for Young African American Breast Cancer Survivors
NCT06892275 The FYI on MRI: A Multilevel Decision Support Intervention for Screening Breast MRI
NCT06747845 Maintenance Niraparib Plus Ipilimumab in Patients With Metastatic Pancreatic Adenocarcinoma Whose Disease Has Not Progressed on Platinum-Based Chemotherapy
NCT03322995 Pancreatic Cancer Adaptive Neoadjuvant Chemotherapy Trial
NCT05705401 Testing Radiation and HER2-targeted Therapy Versus HER2-targeted Therapy Alone for Low-risk HER2-positive Breast Cancer
NCT04513028 Beta Glucan's Effect on Pembrolizumab Immunologic Response in Stage III-IV Melanoma
NCT07025512 177Lu-PSMA-617 in Metastatic Castration Resistant Prostate Cancer (mCRPC) With Bone Marrow Involvement and Cytopenia
NCT05225428 Video Education With Result Dependent dIsclosure
NCT05579366 Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
NCT06147037 A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours
NCT07226154 Prediction of Neoadjuvant Chemotherapy Response in Pancreatic Cancer
NCT06215469 Portable Scalp Cooling System (PSCS) to Prevent Hair Loss for Breast Cancer Patients (Cooler Heads)
NCT06925737 A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
NCT01416714 Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy
NCT05141149 First in Human Phase1/2a Clinical Trial of Anti-PAUF Monoclonal Antibody PBP1510 in Patients With Pancreatic Cancer