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Olive Oil for High Risk Breast Cancer Prevention

Clinicaltrials.gov identifier:
NCT02068092


Study Contact Information:

For additional information, please contact: Houston Methodist Cancer Center by phone: 713-441-0629 or by email.    

Olive Oil for High Risk Breast Cancer Prevention

About the Study

This study will evaluate the effect of hydroxytyrosol, a component of olive oil, on breast density in women who are at high risk for developing breast cancer.

Hydroxytyrosol has been reported to impede the production and spread of various types of human cancer cells. UPDATE: THIS STUDY IS NO LONGER ENROLLING PATIENTS.

Type of Study

This is an , single-group study. All study participants will receive the same treatment and screening.

What the Study Entails

  • Participants will take 25mg hydroxytyrosol orally once daily for 1 year.
  • Participants will have regular mammograms and breast to assess breast density (as determined by ) and the safety/toxicity of hydroxytyrosol.
  • Participants agree to undergo breast biopsy to measure biomarkers related to cancer risk. 
  • Participants will be followed for 3 years.

Study Sites       

  • Houston, Texas
    Houston Methodist Hospital  
    Sub-Investigator: Jenny CN Chang, MD        Sub-Investigator: Daniel Lehane, MD               
  • Houston, Texas
    Methodist Hospital Willowbrook
    Principal Investigator: Anna Belcheva, MD 
  • Sugarland, Texas
    Houston Methodist Hospital Sugar Land
    Principal Investigator: Jorge Darcourt, MD     

Principal Investigator:

Tejal Patel, MD 

This Study is Open To:

UPDATE: THIS STUDY IS NO LONGER ENROLLING PATIENTS.

This Study is Not Open To:

UPDATE: THIS STUDY IS NO LONGER ENROLLING PATIENTS.