Genetic Education for Men (GEM Study)
Study Contact Information:
This study is being conducted at Georgetown University’s Lombardi Comprehensive Cancer Center. For information about the study, please contact the project coordinator, Mary Kate Ladd, by phone at (877) 687-2720 (toll-free) or by email.
A Study in Hereditary Breast and Ovarian Cancer Families to Provide Men With Up-To-Date Information About the Personal Importance of Genetic Testing (GEM)
About the Study
The Genetic Education for Men or GEM study, is a clinical trial evaluating educational tools for men from families in which a BRCA1/2 gene mutation has been identified. In order to identify untested men from BRCA1/2 families, we are seeking women who have received positive BRCA1/2 test results and have at least one untested male relative.
Type of Study
The GEM study is a randomized trial, evaluating a web-based, individually tailored educational tool designed for men from hereditary breast ovarian cancer families. Men who choose to participate will be randomized into one of two treatment groups by chance. Participants will be randomized to receive either an individually tailored web-based genetic education intervention based on their family history, or standard resources about BRCA1/2 testing.
What the study entails
- Individuals who have untested, potentially eligible male relatives should contact the study team for additional information.
- If interested, you can provide the study team with your male relatives’ contact information.
- Please inform relatives that the study will be contacting them by mail and/or email.
- The study team will send study information to potentially eligible male participants.
- Potential participants will have the option to easily decline further contact.
- Interested male participants can provide informed consent and complete a brief survey.
- Participants are randomized to:
- Interactive web-based genetic education.
- Standard print information.
- Participants are asked to complete two brief follow-up over the next 6-months.
- All study participants can choose to undergo free genetic counseling by phone and may choose to pursue genetic testing through the study. Genetic counseling or testing are not required as part of the study.
This study is being conducted at Georgetown University’s Lombardi Comprehensive Cancer Center. Please contact the project coordinator, Mary Kate Ladd, by phone at (877) 687-2720 (toll-free) or email at firstname.lastname@example.org
- Men who are between 25 and 70 years old
- A son, brother, nephew, uncle, or cousin of an individual with a mutation in the BRCA1 or BRCA2 gene
- Men who have been diagnosed with cancer other than non-melanoma skin cancer
- Men who have had prior genetic counseling and/or testing for BRCA1 or BRCA2 mutations