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Enroll in Research > Research Search & Enroll Tool > Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair identifier:


Study Contact Information:

For additional information, please contact: Principal Investigator: Frank A Sinicrope, Alliance for Clinical Trials in Oncology

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

About the Study

may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.

This phase III trial is for people with 3 colon cancer. The study will compare how well treatment with a combination of chemotherapy agents and an agent works compared with treatment with combination chemotherapy agents alone. This study is focused on patients who have a known as or , which are commonly seen in people with

Type of Study

The study is an , 2-arm,  study.   

  • There will be two treatment groups in this study. One group will receive combination chemotherapy along with the drug atezolizumab.  The other group will receive combination chemotherapy alone.
  • The study is randomized; participants will be placed into one of the two study groups by chance.
  • The study is . All participating patients will know which of the two groups they have been assigned to and which treatments they are being given. 

What the Study Entails

People will be assigned randomly to one of two groups:

Group 1: Chemotherapy and

  • People in this group will receive combination chemotherapy intravenously (oxaliplatin, leucovorin calcium and fluorouracil) on day 1, then continuously over 46 hours on days 1-3. Treatment repeats every 14 days for up to 12 cycles in the absence of disease progression or unacceptable .
  • Patients also receive atezolizumab IV starting on day 1 of cycle 1 or 2. Treatment repeats every 14 days for up to 25 cycles in the absence of disease progression or unacceptable .

Group 2: Chemotherapy only

  • People in this group will receive combination chemotherapy intravenously (oxaliplatin, leucovorin calcium, and fluorouracil) on day 1, then continuously over 46 hours on days 1-3. Treatment repeats every 14 days for up to 12 cycles in the absence of disease progression or unacceptable .

Both groups of participants will be followed for up to 5 years.

Study Sites

Alaska Arizona California Colorado Connecticut
Delaware DC Florida Georgia Hawaii
Idaho Illinois Indiana Iowa Kansas
Kentucky Louisiana Maine Maryland Massachusetts
Michigan Minnesota Missouri Montana Nevada
New Hampshire New Jersey New Mexico New York North Carolina
North Dakota Ohio Oklahoma Oregon Pennsylvania
Rhode Island South Carolina South Dakota Tennessee Texas
Utah Virginia Washington West Virginia Wisconsin


  • Anchorage: Katmai Oncology Group; Contact: 907-212-6871 or email    


  • Tucson: Banner University Medical Center - Tucson; Contact by email   
  • Tucson: University of Arizona Cancer Center-North Campus; Contact: 800-327-2873


  • Anaheim: Kaiser Permanente-Anaheim; Contact: 800-398-3996 or email
  • Arroyo Grande: PCR Oncology; Contact: 702-384-0013 or email
  • Auburn: Sutter Auburn Faith Hospital; Contact: 415-209-2686 or email
  • Baldwin Park: Kaiser Permanente-Baldwin Park;Contact: 800-398-3996 or email
  • Bellflower: Kaiser Permanente-Bellflower; Contact: 800-398-3996 or email  
  • Berkeley: Alta Bates Summit Medical Center-Herrick Campus; Contact: 415-209-2686 or email 
  • Clovis: University Oncology Associates; Contact: 559-256-9680     
  • Dublin: Epic Care-Dublin; Contact: 925-875-1677
  • Emeryville: Epic Care Partners in Cancer Care; Contact: 510-629-6682     
  • Fontana: Kaiser Permanente-Fontana; Contact: 800-398-3996 or email
  • Fremont: Palo Alto Medical Foundation-Fremont; Contact by email
  • Harbor City: Kaiser Permanente - Harbor City; Contact: 800-398-3996 or email     
  • Irvine: Kaiser Permanente-Irvine; Contact: 800-398-3996 or  or email  
  • Los Angeles:Kaiser Permanente Los Angeles Medical Center; Contact: 800-398-3996 or email 
  • Los Angeles County-USC Medical Center; Contact: 323-865-0451
  • Los Angeles: USC / Norris Comprehensive Cancer Center; Contact: 323-865-0451 
  • Los Angeles: Kaiser Permanente-Cadillac; Contact: 800-398-3996 or email
  • Martinez: Contra Costa Regional Medical Center; Contact: 925-957-5400
  • Marysville: Fremont - Rideout Cancer Center; Contact: 530-749-4400 
  • Modesto: Memorial Medical Center; Contact: 415-209-2686 or email
  • Mountain View: Palo Alto Medical Foundation-Camino Division; Contact: 415-209-2686 or email   
  • Ontario: Kaiser Permanente-Ontario; Contact: 800-398-3996  or email
  • Orange: UC Irvine Health/Chao Family Comprehensive Cancer Center; Contact: 877-827-8839 or email    
  • Palo Alto: Palo Alto Medical Foundation Health Care; Contact: 415-209-2686 or email
  • Palo Alto: Stanford Cancer Institute Palo Alto; Contact: 650-498-7061 or email  
  • Palo Alto: VA Palo Alto Health Care System; Contact: 800-455-0057
  • Panorama City: Kaiser Permanente - Panorama City; Contact: 800-398-3996 or email
  • Riverside: Kaiser Permanente - Riverside; Contact: 800-398-3996 or email
  • Roseville: Sutter Roseville Medical Center; Contact: 415-209-2686 or email
  • Sacramento: Sutter Medical Center Sacramento; Contact: 415-209-2686 or email 
  • Sacramento: University of California Davis Comprehensive Cancer Center; Contact: 916-734-3089
  • Salinas: Salinas Valley Memorial; Contact: 831-759-1838 or email
  • San Diego: Kaiser Permanente-San Diego Zion; Contact: 800-398-3996 or email
  • San Diego: Sharp Memorial Hospital; Contact: 858-939-5062 or email
  • San Francisco: California Pacific Medical Center-Pacific Campus; Contact:  415-209-2686 or email  
  • San Marcos: Kaiser Permanente-San Marcos; Contact: 800-398-3996 or email
  • Santa Cruz: Palo Alto Medical Foundation-Santa Cruz; Contact: Site Public Contact: 415-209-2686 or email  
  • Sunnyvale: Palo Alto Medical Foundation-Sunnyvale; Contact: Site Public Contact: 415-209-2686 or email  
  • Vellego:  Sutter Solano Medical Center/Cancer Center; Contact: Site Public Contact: 415-209-2686 or email  
  • Woodland Hills: Kaiser Permanente-Woodland Hills; Contact: 800-398-3996 or email


  • Aurora: Rocky Mountain Cancer Centers-Aurora; Contact: 303-777-2663 or email     
  • Aurora: University of Colorado Hospital; Contact:720-848-0650 
  • Boulder: Boulder Community Hospital; Contact 303-777-2663 or email
  • Boulder: Rocky Mountain Cancer Centers-Boulder; Contact 303-777-2663 or email
  • Colorado Springs: Penrose-Saint Francis Healthcare; Contact: 308-398-6518 or email
  • Colorado Springs: UCHealth Memorial Hospital Central; Contact: 719-365-2406
  • Colorado Springs: Memorial Hospital North; Contact: 719-364-6700
  • Denver: Kaiser Permanente-Franklin; Contact: 303-764-5056 or email 
  • Denver: National Jewish Health-Main Campus; Contact: 877-225-5654 or email   
  • Denver: Rocky Mountain Cancer Centers-Midtown; Contact: 303-777-2663 or email
  • Denver: SCL Health Saint Joseph Hospital; Contact: 303-777-2663 or email 
  • Denver: Rocky Mountain Cancer Centers-Rose; Contact: 303-777-2663 or email
  • Englewood: Swedish Medical Center; Contact: 303-777-2663 or email
  • Englewood: Mountain Blue Cancer Care Center - Swedish; Contact: 303-777-2663 or email
  • Fort Collins: Poudre Valley Hospital; Contact: 970-297-6150        
  • Fort Collins: Cancer Care and Hematology-Fort Collins; Contact: 888-823-5923 or email
  • Golden: National Jewish Health-Western Hematology Oncology; Contact: 303-777-2663 or email  
  • Grand Junction:Saint Mary's Hospital and Regional Medical Center; Contact: 303-777-2663 or email
  • Greeley: North Colorado Medical Center; Contact: 303-777-2663 or email   
  • Greeley: UCHealth Greeley Hospital;Contact: 888-823-5923 or email   
  • Lafayette: Good Samaritan Medical Center; Contact: 303-673-1622        
  • Lafayette: Kaiser Permanente-Rock Creek; Contact: 303-764-5056 or email 
  • Littleton: Rocky Mountain Cancer Centers-Littleton; Contact: 303-777-2663 or email  
  • Lone Tree: Kaiser Permanente-Lone Tree; Contact: 303-764-5056 or email 
  • Lone Tree: Rocky Mountain Cancer Centers-Sky Ridge; Contact: 303-777-2663 or email
  • Longmont: Longmont United Hospital; Contact: 308-398-6518 or email    
  • Loveland: Medical Center of the Rockies; Contact: 970-203-7083    
  • Loveland: McKee Medical Center; Contact: 303-777-2663 or email        
  • Thornton: National Jewish Health-Northern Hematology Oncology; Contact: 303-777-2663  or email    
  • Wheat Ridge: SCL Health Lutheran Medical Center; Contact: 303-777-2663  or email       


  • Derby: Smilow Cancer Hospital-Derby Care Center; Contact: 203-785-5702 or email
  • Fairfield: Smilow Cancer Hospital Care Center-Fairfield; Contact:  203-785-5702  or email  
  • Guildford: Smilow Cancer Hospital Care Center - Guiford; Contact: 203-785-5702  or email  
  •  Hartford: Smilow Cancer Hospital Care Center at Saint Francis; Contact: 203-785-5702  or email  
  • Middletown: Middlesex Hospital; Contact: 860-358-2058 or email   
  • New Haven: Yale University; Contact: 203-785-5702  or email 
  • North Haven: Yale-New Haven Hospital North Haven Medical Center; Contact: 203-785-5702  or email  
  • Torrington: Smilow Cancer Hospital-Torrington Care Center ;Contact: 203-785-5702  or email  
  • Trumbull: Smilow Cancer Hospital Care Center-Trumbull; Contact: 203-785-5702 or email   
  •  Waterbury: Smilow Cancer Hospital-Waterbury Care Center; Contact: 203-785-5702 or email 
  •  Waterford: Smilow Cancer Hospital-Waterford Care Center; Contact: 203-785-5702 or email 


  • Frankford: Beebe South Coastal Health Campus; Contact: 302-645-3100 or email      
  • Newark: Helen F Graham Cancer Center; Contact: 302-623-4450 or email           
  • Newark: Medical Oncology Hematology Consultants PA; Contact: 302-623-4450 or email      
  • Rehoboth Beach: Beebe Health Campus; Contact: 302-645-3100 or email    

District of Columbia

  • Sibley Memorial Hospital; Contact: 202-243-2373 or email         


  • Aventura: Mount Sinai Comprehensive Cancer Center at Aventura; Contact: 305-674-2625 or email        
  • Daytona Beach: Halifax Health Medical Center-Centers for Oncology; Contact: 386-254-4211     
  • Fort Lauderdale: Broward Health Medical Center; Contact: 954-355-5346         
  • Fort Myers: Regional Cancer Center-Lee Memorial Health System; Contact: 773-702-9171 or email     
  • Miami Beach: Mount Sinai Medical Center; Contact:305-674-2625 or email    
  • Orlando: AdventHealth Orlando; Contact: 407-303-2090 or email        


  • Albany: Phoebe Putney Memorial Hospital Contact:    229-312-0405 or email    
  • Athens: University Cancer and Blood Center LLC; Contact: 706-353-5006 or email    
  • Augusta: Augusta Oncology Associates PC-D'Antignac; Contact: 706-821-2944  
  • Augusta: Augusta Oncology Associates PC-Wheeler; Contact: 706-736-1830        


  • 'Aiea: Pali Momi Medical Center; Contact: 808-486-6000        
  • Honolulu: Queen's Cancer Cenrer - POB I; Contact: 808-532-0315
  • Honolulu: Queen's Medical Center; Contact: 808-545-8548     
  • Honolulu: Straub Clinic and Hospital; Contact: 808-522-4333    
  • Honolulu: Queen's Cancer Center - Kuakini; Contact: 808-531-8521    


  • Boise: Saint Alphonsus Cancer Care Center-Boise; Contact: 734-712-3671 or email     
  • Boise: Saint Luke's Mountain States Tumor Institute; Contact: 208-381-2774 or email     
  • Caldwell: Saint Alphonsus Cancer Care Center-Caldwell; Contact: 734-712-3671 or email     
  • Coeur d'Alene: Kootenai Medical Center; Contact: 406-969-6060 or email      
  • Fruitland: Saint Luke's Cancer Institute - Fruitland; Contact: 208-381-2774 or email      
  • Meridian: Saint Luke's Cancer Institute - Meridian; Contact: 208-381-2774 or email      
  • Nampa: Saint Alphonsus Medical Center-Nampa; Contact: 734-712-3671 or email     
  • Nampa: Saint Luke's Cancer Institute - Nampa; Contact: 208-381-2774 or email     
  • Post Falls: Kootenai Cancer Center; Contact: 406-969-6060 or email     
  • Sandpoint: Kootenai Cancer Center; Contact: 406-969-6060 or email      
  • Twin Falls:Saint Luke's Cancer Institute - Twin Falls; Contact: 208-381-2774 or email    


  • Bloomington: Illinois CancerCare-Bloomington; Contact:  309-243-3605 or email        
  • Canton: Illinois CancerCare-Canton; Contact:  309-243-3605 or email       
  • Carterville: SIH Cancer Institute; Contact: 618-985-3333 or email     
  • Carthage: Illinois CancerCare-Carthage; Contact:  309-243-3605 or email       
  • Centralia: Centralia Oncology Clinic; Contact: 217-876-4740 or email       
  • Chicago: Northwestern University; Contact: 312-695-1301 or email     
  • Chicago: Rush University Medical Center; Contact : 312-942-5498 or email       
  • Crystal Lake: AMG Crystal Lake - Oncology; Contact: Site Public Contact    630-929-6129  or email      
  • Decatur: Cancer Care Specialists of Illinois - Decatur; Contact: 217-876-4740 or email       
  • Dixon: Illinois CancerCare-Dixon; Contact    815-285-7800      
  • Eureka: Illinois CancerCare-Eureka; Contact 309-243-3605  or email      
  • Evanston: NorthShore University HealthSystem-Evanston Hospital; Contact: 847-570-2109     
  • Freeport: Freeport Memorial Hospital/Leonard C Ferguson Cancer Center; Contact: 815-599-7000     
  • Galesburg: Illinois CancerCare-Galesburg; Contact: 309-243-3605
  • Geneva: Northwestern Medicine Cancer Center Delnor; Contact: 630-352-5360  
  • Glenview: NorthShore University HealthSystem-Glenbrook Hospital; Contact: 847-570-2109
  • Harvey:Ingalls Memorial Hospital; Contact: 708-915-4673  
  • Highland Park: NorthShore University HealthSystem-Highland Park Hospital: Contact: 847-570-2109  
  • Kewanee: Illinois CancerCare-Kewanee Clinic; Contact: 309-243-3605  
  • Lake Forest: Northwestern Medicine Lake Forest Hospital: Contact:
  • Libertyville: AMG Libertyville - Oncology; Contact: 630-929-6129  
  • Macomb: Illinois CancerCare-Macomb; Contact: 309-243-3605  
  • Maywood: Loyola University Medical Center; Contact: 708-226-4357     
  • Mount Vernon: Good Samaritan Regional Health Center; Contact:    618-242-4600
  • O'Fallon: Cancer Care Center of O'Fallon; Contact    217-876-4762  
  • Ottawa: Illinois CancerCare-Ottawa Clinic; Contact: 309-243-3605  
  • Park Ridge: Advocate Lutheran General Hospital; Contact: 847-384-3621
  • Pekin: Illinois CancerCare-Pekin; Contact: 309-243-3605  
  • Peoria: Illinois CancerCare-Peoria; Contact: 309-243-3605  
  • Peru: Illinois CancerCare-Peru; Contact: 309-243-3605  
  • Princeton: Illinois CancerCare-Princeton; Contact: 309-243-3605
  • Silvis: Genesis Cancer Center - Silvis; Contact: 563-421-1908
  • Springfield: Southern Illinois University School of Medicine; Contact: 217-545-7929     
  • Springfield: Springfield Clinic; Contact: 800-444-7541
  • Warrenville: Northwestern Medicine Cancer Center Warrenville; Contact: 630-352-5360  


  • Indianapolis: Indiana University/Melvin and Bren Simon Cancer Center; Contact: 317-278-5632
  • Indianapolis: Sidney and Lois Eskenazi Hospital Contact    317-278-5632
  • Indianapolis: Franciscan Health Indianapolis; Contact: 317-528-7060     
  • Mooresville: Franciscan Health Mooresville; Contact: 317-834-3603
  • Richmond: Reid Health; Contact: 937-528-2900
  • Terre Haute: Union Hospital; Contact: 812-238-7394     


  • Ames: Mary Greeley Medical Center; Contact: 515-956-4132
  • Ames: McFarland Clinic PC - Ames; Contact: 515-239-4734
  • Bettendorf: University of Iowa Healthcare Cancer Services Quad Cities; Contact: 563-355-7733
  • Boone: McFarland Clinic PC-Boone; Contact: 515-956-4132
  • Cedar Rapids: Mercy Hospital; Contact: 319-365-4673
  • Cedar Rapids: Oncology Associates at Mercy Medical Center; Contact    319-363-2690     
  • Clive: Medical Oncology and Hematology Associates-West Des Moines; Contact: 308-398-6518  
  • Clive: Mercy Cancer Center-West Lakes; Contact: 308-398-6518  
  • Davenport: Genesis Medical Center - East Campus; Contact: 563-421-1908 
  • Davenport: Iowa Cancer Specialists; Contact: 563-421-1908
  • Des Moines: Iowa Methodist Medical Center; Contact: 515-241-6727 
  • Des Moines: Medical Oncology and Hematology Associates-Des Moines; Contact: 515-282-2921 
  • Des Moines: Broadlawns Medical Center; Contact: 515-282-2200
  • Des Moines: Medical Oncology and Hematology Associates-Laurel; Contact: 308-398-6518 
  • Des Moines: Mercy Medical Center - Des Moines; Contact: 308-398-6518
  • Fort Dodge: McFarland Clinic PC-Trinity Cancer Center; Contact : 515-956-4132     
  • Iowa City: University of Iowa/Holden Comprehensive Cancer Center; Contact: 800-237-1225     
  • Jefferson: McFarland Clinic PC-Jefferson; Contact: 515-956-4132
  • Marshalltown: McFarland Clinic PC-Marshalltown; Contact: 515-956-4132     
  • Sioux City: Siouxland Regional Cancer Center; Contact: 712-252-9326  
  • West Des Moines: Mercy Medical Center-West Lakes; Contact: 308-398-6518    


  • Hays: HaysMed University of Kansas Health System
  • Kansas City:University of Kansas Cancer Center-West; Contact: 913-588-3671 or email      
  • Liberal: Cancer Center of Kansas-Liberal; Contact: 316-268-5374 or email
  • Olathe: Olathe Health Cancer Center; Contact: 913-355-8000  
  • Overland Park: University of Kansas Cancer Center-Overland Park; Contact: 913-588-3671  
  • Pittsburg: Ascension Via Christi - Pittsburg; Contact: 620-235-7900
  • Salina: Salina Regional Health Center;  Contact: 785-452-7038
  • Topeka: University of Kansas Health System Saint Francis Campus; Contact: 785-295-8000   
  • Westwood: University of Kansas Hospital-Westwood Cancer Center; Contact: 913-588-3671
  • Wichita: Cancer Center of Kansas-Wichita Medical Arts Tower; Contact: 316-268-5374  


  • Edgewood: Saint Elizabeth Medical Center South; Contact: 859-301-5473  
  • Fort Thomas: Saint Elizabeth Fort Thomas; Contact    859-301-9418
  • Lexington: Baptist Health Lexington; Contact: 859-260-6425
  • Lexington: Saint Joseph Hospital East; Contact:  308-398-6518 
  • Lexington: University of Kentucky/Markey Cancer Center; Contact: 859-257-3379     


  • Baton Rouge: LSU Health Baton Rouge-North Clinic; Contact: 225-215-1353
  • Baton Rouge: Louisiana Hematology Oncology Associates LLC; Contact: 225-215-1353  
  • Baton Rouge: Mary Bird Perkins Cancer Center; Contact: 225-215-1353  
  • Baton Rouge: Our Lady of the Lake - Medical Oncology; Contact: 225-215-1353  
  • Kenner: Ochsner Medical Center Kenner; Contact: 504-464-8314     
  • New Orleans: Ochsner Medical Center Jefferson; Contact: 504-703-8712  


  • Augusta: Harold Alfond Center for Cancer Care; Contact: 207-626-4855     
  • Belfast: Waldo County General Hospital; Contact: 207-338-2500     
  • Biddeford:  MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford; Contact 
  • Brewer: Lafayette Family Cancer Center-EMMC; Contact:    800-987-3005     
  • Rockport: Penobscot Bay Medical Center; Contact: 207-396-8670  
  • Sanford: MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford; Contact 
  • South Portland: Maine Medical Partners - South Portland; Contact: 207-396-8670  


  • Baltimore: Saint Agnes Hospital; Contact: 410-368-2910     
  • Baltimore: Johns Hopkins University/Sidney Kimmel Cancer Center; Contact: 410-955-8804  
  • Glen Burnie: UM Baltimore Washington Medical Center/Tate Cancer Center; Contact: 410-553-8100          


  • Boston: Boston Medical Center; Contact: 617-638-8265     
  • Boston: Beth Israel Deaconess Medical Center; Contact: 617-667-9925     
  • Boston: Dana-Farber Cancer Institute; Contact: 877-442-3324       


  • Ann Arbor: Saint Joseph Mercy Hospital; Contact: 734-712-3671  
  • Battle Creek: Bronson Battle Creek; Contact: 616-391-1230          
  • Bay City: McLaren Cancer Institute-Bay City; Contact: 313-576-9790 
  • Bloomfield: McLaren Cancer Institute-Bloomfield; Contact: 313-576-9790  
  • Brighton: IHA Hematology Oncology Consultants-Brighton; Contact: 734-712-3671  
  • Brighton: Saint Joseph Mercy Brighton; Contact: 734-712-3671  
  • Brownstown: Henry Ford Cancer Institute-Downriver; Contact: 313-916-3721
  • Canton: IHA Hematology Oncology Consultants-Canton; Contact: 734-712-3671  
  • Canton: Saint Joseph Mercy Canton; Contact: 734-712-3671  
  • Chelsea: IHA Hematology Oncology Consultants-Chelsea; Contact: 734-712-3671 or email  
  • Chelsea: Saint Joseph Mercy Chelsea; Contact: 734-712-3671 or email   
  • Clarkston: Hematology Oncology Consultants-Clarkston; Contact: 734-712-3671 or email      
  • Clarkston: McLaren Cancer Institute-Clarkston; Contact: 313-576-9790 or email  
  • Dearborn: Beaumont Hospital-Dearborn; Contact: 248-551-7695
  • Dearborn: Henry Ford Medical Center-Fairlane; Contact: 313-916-3721 or email
  • Detroit:Wayne State University/Karmanos Cancer Institute; Contact: 313-576-9790 or email 
  • Detroit: Henry Ford Hospital; Contact: 313-916-3721 or email
  • East China Township: Great Lakes Cancer Management Specialiists - Doctors Park; Contact: 734-712-3671 or email 
  • Farmington Hills: Weisberg Cancer Treatment Center; Contact: 313-576-9790 or email
  • Flint: McLaren Cancer Institute-Flint; ; Contact: 313-576-9790 or by email 
  • Flint: Genessee Cancer and Blood Disease Center: Contact: 734-712-3671 or email          
  • Flint: Singh and Arora Hematology Oncology PC; Contact: 313-576-9790 or email 
  • Grand Rapids: Spectrum Health at Butterworth Campus; Contact: 616-391-1230 or email
  • Grosse Point Woods: Academic Hematology Oncology Specialists; Contact: 734-712-3671 or email  
  • Grosse Point Woods: Great Lakes Cancer Management Specialists-Van Elslander Cancer Center; Contact: 734-712-3671 or email   
  • Jackson: Allegiance Health; Contact: 313-916-3721 or by email
  • Kalamazoo: West Michigan Cancer Center; Contact: 616-391-1230 or email
  • Lansing: McLaren-Greater Lansing; Contact: 313-576-9790 or email  
  • Lansing: Sparrow Hospital; Contact: 734-712-3671 or email  
  • Lapeer: McLaren Cancer Institute-Lapeer Region; Contact: 313-576-9790 or email 
  • Livonia: Hope Cancer Clinic; Contact: 734-712-3671 or email    
  • Livonia: Saint Mary Mercy Hospital; Contact: 734-712-3671 or email  
  • Mount Clemens: McLaren Cancer Institute-Macomb; Contact: 313-576-9790 or email       
  • Mount Pleasant: McLaren Cancer Institute-Central Michigan; Contact: 313-576-9790 or email  
  • Novi: Henry Ford Medical Center-Columbus; Contact: 313-916-3721 or by email        
  • Petoskey: McLaren Cancer Institute-Northern Michigan; Contact: 313-576-9790 or email          
  • Pontiac: Saint Joseph Mercy Oakland; Contact: 734-712-3671 or email   
  • Port Huron: McLaren-Port Huron; Contact: 313-576-9790 or email 
  • Royal Oak: William Beaumont Hospital-Royal Oak; Contact: 248-551-7695  
  • Saginaw: Ascension Saint Mary's Hospital; Contact: 734-712-3671 or email     
  • Southfield: Ascension Providence Hospitals - Southfield; Contact: 248-849-5332 or email      
  • Tawas City: Ascension Saint Joseph Hospital; Contact: 734-712-3671 or email   
  • Traverse City: Munson Medical Center; Contact: 616-391-1230 or email
  • Troy: William Beaumont Hospital-Troy; Contact: 248-551-7695
  • Warren: Great Lakes Cancer Management Specialists-Macomb Professional Building; Contact: 734-712-3671 or email 
  • West Bloomfield: Henry Ford West Bloomfield Hospital; Contact: 313-916-3721 or by email 
  • West Branch: Saint Mary's Oncology/Hematology Associates of West Branch; Contact: 734-712-3671 or email 
  • Ypsilanti: IHA Hematology Oncology Consultants-Ann Arbor; Contact: 734-712-3671 or email


  • Albert Lea: Mayo Clinic Health System in Albert Lea; Contact: 855-776-0015
  • Bemidji: Sanford Joe Lueken Cancer Center; Contact: 218-333-5000   
  • Burnsville: Fairview Ridges Hospital; Contact: 952-993-1517 
  • Coon Rapids: Mercy Hospital; Contact: 952-993-1517  
  • Deer River: Essentia Health - Deer River Clinic; Contact: 218-786-3308  
  • Duluth: Essentia Health Cancer Center; Contact: 218-786-3308  
  • Edina: Fairview Southdale Hospital; Contact:    952-993-1517  
  • Fridley: Unity Hospital; Contact: 952-993-1517  
  • Hibbing: Essentia Health Hibbing Clinic; Contact: 218-786-3308     
  • Mankato: Mayo Clinic Health Systems-Mankato; Contact: 855-776-0015     
  • Maplewood: Minnesota Oncology Hematology PA-Maplewood; Contact: 952-993-1517  
  • Maplewood: Saint John's Hospital - Healtheast; Contact: 952-993-1517  
  • Minneapolis: Abbott-Northwestern Hospital; Contact: 952-993-1517  
  • Minneapolis: Hennepin County Medical Center; Contact: 952-993-1517  
  • Minneapolis: Health Partners; Contact: 952-993-1517
  • Rochester: Mayo Clinic in Rochester; Contact: 855-776-0015     
  • Saint Cloud: Coborn Cancer Center at Saint Cloud Hospital; Contact: 877-229-4907  
  • Saint Louis Park: Park Nicollet Clinic - Saint Louis Park; Contact: 952-993-1517  
  • Saint Paul: Regions Hospital; Contact: 952-993-1517  
  • Saint Paul: United Hospital; Contact: 952-993-1517  
  • Sandstone: Essentia Health Sandstone; Contact    218-786-3308
  • Stillwater: Lakeview Hospital; Contact: 952-993-1517  
  • Virginia: Essentia Health Virginia Clinic; Contact: 218-786-3308
  • Waconia: Ridgeview Medical Center; Waconia, Minnesota, 55387
  • Wilmar: Rice Memorial Hospital; Contact: 952-993-1517  
  • Woodbury: Minnesota Oncology Hematology PA-Woodbury; Contact: 952-993-1517  


  • Ballwin: Saint Louis Cancer and Breast Institute-Ballwin; Contact: 314-251-7058     
  • Cape Girardeau: Saint Francis Medical Center; Contact: 573-334-2230
  • Cape Girardeau: Southeast Cancer Center; Contact: 573-651-5550
  • Columbia: University of Missouri - Ellis Fischel; Contact: 573-882-7440
  • Creve Coeur: Siteman Cancer Center at West County Hospital; Contact: 800-600-3606
  • Joplin: Mercy Hospital Joplin; Contact: 417-556-3074        
  • Kansas City: Truman Medical Centers; Contact: 816-404-4375     
  • Kansas City: University of Kansas Cancer Center - North; Contact: 913-588-3671  
  • Lee's Summit: University of Kansas Cancer Center - Lee's Summit; Contact: 913-588-3671  
  • Saint Louis: Washington University School of Medicine; Contact: 800-600-3606  
  • Saint Louis: Siteman Cancer Center-South County; Contact: 800-600-3606  
  • Saint Louis: Missouri Baptist Medical Center; Contact: 314-996-5569     
  • Saint Louis: Siteman Cancer Center at Christian Hospital; Contact: 800-600-3606  
  • Saint Peters: Siteman Cancer Center at Saint Peters Hospital; Contact: 800-600-3606  
  • Sainte Genevieve: Sainte Genevieve County Memorial Hospital; Contact: 314-996-5569     
  • Springfield: Mercy Hospital Springfield; Contact: 417-269-4520      
  • Sullivan: Missouri Baptist Sullivan Hospital; Contact: 314-996-5569     
  • Sunset Hills: Missouri Baptist Outpatient Center-Sunset Hills; Contact: 314-996-5569     


  • Anaconda: Community Hospital of Anaconda; Contact: 406-969-6060  
  • Billings: Billings Clinic Cancer Center; Contact    800-996-2663 
  • Bozeman: Bozeman Deaconess Hospital; Contact: 406-969-6060 
  • Great Falls: Benefis Healthcare- Sletten Cancer Institute; Contact: 406-969-6060
  • Kalispell: Kalispell Regional Medical Center; Contact: 406-969-6060
  • Missoula: Community Medical Hospital; Contact    406-969-6060   


  • Grand Island: CHI Health Saint Francis; Contact: 308-398-6518  
  • Kearney: CHI Health Good Samaritan; Contact: 308-398-6518  
  • Omaha: Nebraska Methodist Hospital; Contact: 402-354-5144     
  • Omaha: Nebraska Medicine-Village Pointe; Contact: 402-559-5600     
  • Omaha: Alegent Health Bergan Mercy Medical Center; Contact: 308-398-6518    
  • Omaha: University of Nebraska Medical Center; Contact: 402-559-6941    


  • Henderson: OptumCare Cancer Care at Seven Hills; Contact: 702-384-0013
  • Las Vegas: OptumCare Cancer Care at Oakey/MountainView and Fort Apache; Contact    702-384-0013  
  • Reno: Renown Regional Medical Center; Contact: 702-384-0013  

New Hampshire

  • Concord: New Hampshire Oncology Hematology PA-Concord; Contact: 603-224-2556
  • Exeter: Exeter Hospital; Contact    800-439-3837
  • Lebanon: Dartmouth Hitchcock Medical Center; Contact: 800-639-6918 
  • Manchester: Solinsky Center for Cancer Care; Contact: 800-339-6484     

New Jersey

  • Basking Ridge: Memorial Sloan Kettering Basking Ridge; Contact: 212-639-7592     
  • Egg Harbor Township: AtlantiCare Surgery Center; Contact    609-748-7200 
  • Hamilton: The Cancer Institute of New Jersey Hamilton; Contact: 609-631-6946
  • Middletown:  Memorial Sloan Kettering Monmouth; Contact:   212-639-7592
  • Montvale: Memorial Sloan Kettering Bergen; Contact: 212-639-7592
  • Morristown: Morristown Medical Center; Contact: 973-971-5900
  • Mulica Hill: Inspira Medical Center Mullica Hill; Contact: 856-508-3500
  • New Brunswick: Rutgers Cancer Institute of New Jersey; Contact: 732-235-7356
  • Newark: Newark Beth Israel Medical Center; Contact: 973-926-7230 
  • Paramus:  The Valley Hospital-Luckow Pavilion; Contact: 201-634-5792
  • Somerville:Robert Wood Johnson University Hospital Somerset; Contact: 908-685-2481    

New Mexico

  • Albuquerque: University of New Mexico Cancer Center; Contact: 505-925-0366
  • Albuquerque: Presbyterian Kaseman Hospital; Contact: 505-559-6113
  • Rio Rancho: Presbyterian Rust Medical Center/Jorgensen Cancer Center; Contact: 505-559-6113   

New York

  • Auburn: Hematology Oncology Associates of Central New York-Auburn; Contact: 315-472-7504
  • Brooklyn: Maimonides Medical Center; Contact: 718-765-2500 
  • Buffalo: Roswell Park Cancer Institute; Contact: 800-767-9355
  • Commack: Memorial Sloan Kettering Commack; Contact: 212-639-7592
  • Cooperstown: Mary Imogene Bassett Hospital; Contact    877-547-1750     
  • East Hills: Cancer Institute at Saint Francis Hospital; Contact: 773-702-9171  
  • East Syracuse: Hematology Oncology Associates of Central New York-East Syracuse; Contact: 315-472-7504     
  • Elmira: Arnot Ogden Medical Center/Falck Cancer Center; Contact: 607-271-7000
  • Harrison: Memorial Sloan Kettering Westchester; Contact: 212-639-7592
  • New York: Mount Sinai West;  Contact: 212-824-7309     
  • New York: NYP/Columbia University Medical Center; Contact: 212-305-6361      
  • New York: Memorial Sloan Kettering Cancer Center: Contact    212-639-7592
  • New York: NYP/Weill Cornell Medical Center; Contact: 212-746-1848 
  • Stony Brook: Stony Brook University Medical Center; Contact: 800-862-2215     
  • Syracuse: State University of New York Upstate Medical University; Contact    315-464-5476
  • Syracuse: Hematology Oncology Associates of Central New York-Onondaga Hill; Contact    315-472-7504
  • Uniondale: Memorial Sloan Kettering Nassau; Contact: 212-639-7592       
  • White Plains: Dickstein Cancer Treatment Center; Contact: 914-849-7582  

North Carolina

  • Albemarle: Atrium Health Stanly/LCI-Albemarle; Contact: 800-804-9376
  • Asheboro: Randolph Hospital; Contact: 336-832-0836
  • Asheville: AdventHealth Infusion Center Asheville; Contact: 828-650-8037  
  • Burlington: Cone Health Cancer Center at Alamance Regional; Contact: 336-538-7725 
  • Charlotte: Carolinas Medical Center/Levine Cancer Institute; Contact: 800-804-9376
  • Charlotte: Atrium Health Pineville/LCI-Pineville; Contact: 980-442-2000
  • Charlotte: Levine Cancer Institute-SouthPark; Contact: 980-442-2000
  • Charlotte: Levine Cancer Institute-Ballantyne; Contact: 800-804-9376
  • Clinton: Southeastern Medical Oncology Center-Clinton; Contact: 919-587-9084
  • Clyde: AdventHealth Infusion Center Haywood; Contact: 828-650-8037
  • Concord: Atrium Health Cabarrus/LCI-Concord; Contact: 800-804-9376 
  • Durham: Duke University Medical Center; Contact    888-275-3853
  • Gastonia: Levine Cancer Institute-Gaston; Contact: 800-804-9376
  • Goldsboro: Southeastern Medical Oncology Center-Goldsboro; Contact: 919-587-9084 
  • Greensboro: Cone Health Cancer Center; Contact: 336-832-0821
  • Greenville: East Carolina University; Contact  252-744-1015  
  • Hendersonville: Margaret R Pardee Memorial Hospital; Contact: 828-696-4716
  • Hendersonville: AdventHealth Hendersonville; Contact: 828-650-8037
  • Jacksonville: Southeastern Medical Oncology Center-Jacksonville; Contact    910-587-9084
  • Kenansville: Vidant Oncology-Kenansville; Contact: 252-559-2201  
  • Kinston: Vidant Oncology-Kinston; Contact    252-559-2201  
  • Lincolnton: Atrium Health Lincoln/LCI-Lincolnton; Contact: 800-804-9376
  • Monroe: Atrium Health Union/LCI-Union; Contact:   980-442-2000
  • Shelby: Atrium Health Cleveland/LCI-Cleveland; Contact: 800-804-9376 
  • Washington: Marion L Shepard Cancer Center at Vidant Beaufort Hospital                 

North Dakota

  • Bismark: Sanford Bismarck Medical Center; Contact: 701-323-5760
  • Fargo:  Sanford Broadway Medical Center; Contact: 701-323-5760      
  • Fargo:  Sanford Roger Maris Cancer Center; Contact    701-234-6161
  • Minot: Trinity Cancer Care Center; Contact: 800-862-0005


  • Beavercreek: Indu and Raj Soin Medical Center; Contact:  937-528-2900
  • Belpre:  Strecker Cancer Center-Belpre; Contact: 800-523-3977   
  • Canton: Mercy Medical Center; Contact: 888-293-4673     
  • Canton: Aultman Health Foundation; Contact: 330-363-7274           
  • Centerville: Miami Valley Hospital South; Contact: 937-528-2900  
  • Cincinnati: Good Samaritan Hospital – Cincinnati; Contact: 308-398-6518
  • Cleveland: Cleveland Clinic Cancer Center/Fairview Hospital; Contact    866-223-8100  
  • Columbus: Ohio State University Comprehensive Cancer Center; Contact:  800-293-5066  
  • Columbus: Columbus Oncology and Hematology Associates; Contact: 614-488-2118  
  • Columbus:  Grant Medical Center; Contact    614-566-4475
  • Columbus:   The Mark H Zangmeister Center ; Contact: 614-488-2118  
  • Columbus: Doctors Hospital; Contact: 614-566-3275  
  • Dayton: Dayton Physician-Miami Valley Hospital North; Contact:  937-528-2900  
  • Delaware: Delaware Health Center-Grady Cancer Center; Contact: 740-615-0227  
  • Mansfield: OhioHealth Mansfield Hospital; Contact    419-526-8018  
  • Mansfield: Cleveland Clinic Cancer Center Mansfield; Contact: 866-223-8100
  • Marietta:  Marietta Memorial Hospital; Contact    800-523-3977  
  • Marion: OhioHealth Marion General Hospital; Contact: 614-488-2118  
  • Mayfield Heights: Hillcrest Hospital Cancer Center; Contact    866-223-8100
  • Newark: Licking Memorial Hospital; Contact: 740-348-4000  
  • Portsmouth: Southern Ohio Medical Center; Contact: 614-488-2118  
  • Sandusky: North Coast Cancer Care; Contact: 866-223-8100 
  • Strongsville:  Cleveland Clinic Cancer Center Strongsville; Contact: 866-223-8100  
  • Syvania: ProMedica Flower Hospital; Contact:  419-824-1842     
  • Toledo: Toledo Clinic Cancer Centers-Toledo; Contact: 800-444-3561     
  • Warrensville Heights: South Pointe Hospital; Contact: 866-223-8100  
  • Wooster: Cleveland Clinic Wooster Family Health and Surgery Center; Contact: 866-223-8100
  • Youngstown: Saint Elizabeth Youngstown Hospital; Contact: 937-528-2900 
  • Zanesville: Genesis Healthcare System Cancer Care Center; Contact: 740-454-5232      


  • Lawton: Cancer Centers of Southwest Oklahoma Research; Contact: 877-231-4440          
  • Oklahoma City: University of Oklahoma Health Sciences Center; Contact: 405-271-8777  
  • Oklahoma City: Mercy Hospital Oklahoma City; Contact: 405-752-3402     
  • Tulsa: Oklahoma Cancer Specialists and Research Institute-Tulsa; Contact: 918-505-3200     


  • Clackamas: Providence Cancer Institute Clackamas Clinic; Contact: 503-215-2614  
  • Newberg: Providence Newberg Medical Center; Contact: 503-215-2614    
  • Ontario: Saint Alphonsus Medical Center-Ontario; Contact: 734-712-3671  
  • Portland: Providence Portland Medical Center; Contact: 503-215-2614        
  • Portland: Providence Saint Vincent Medical Center; Contact: 503-215-2614  


  • Allentown: Lehigh Valley Hospital-Cedar Crest; Contact: 734-712-3671      
  • BethlehemSaint Luke's University Hospital-Bethlehem; Contact: 484-503-4151   
  • Bethlehem: Lehigh Valley Hospital - Muhlenberg; Contact:734-712-3671    
  • Bryn Mawr: Bryn Mawr Hospital; Contact: 484-476-2649
  • Chambersburg: Chambersburg Hospital: Contact    773-702-9171  
  • Danville: Geisinger Medical Center; Contact: 570-271-5251      
  • Ephrata: Ephrata Cancer Center; Contact: 717-721-4840     
  • Gettysburg: Adams Cancer Center; Contact: 877-441-7957     
  • Harrisburg: UPMC Pinnacle Cancer Center/Community Osteopathic Campus; Contact: 717-724-6765
  • Hazleton: Geisinger Medical Center-Cancer Center Hazleton; Contact : 570-459-2901
  • Jefferson Hills:Jefferson Hospital; Contact: 412-359-3043   
  • Lebanon: Sechler Family Cancer Center; Contact: 717-741-8303  
  • Lewisburg: Geisinger Medical Oncology-Lewisburg; Contact: 570-374-8555
  • Media: Riddle Memorial Hospital; Contact: 484-476-2649
  • Monroeville: Forbes Hospital; Contact: 412-858-7746     
  • Natrona Heights: Allegheny Valley Hospital; Contact: 724-226-7380     
  • Paoli: Paoli Memorial Hospital: Contact    484-476-2649  
  • Philadelphia: Temple University Hospital; Contact :  215-728-2983     
  • Pittsburgh: Allegheny General Hospital; Contact : 877-284-2000       
  • Pittsburgh: West Penn Hospital; Contact: 412-578-5000          
  • Pittsburgh: University of Pittsburgh Cancer Institute (UPCI); Contact: 412-647-8073      
  • Pottsville: Geisinger Cancer Services-Pottsville; Contact: 800-275-6401  
  • Sayre: Guthrie Medical Group PC-Robert Packer Hospital; Contact:  800-836-0388     
  • Scranton: Community Medical Center; Contact : 570-703-4768 
  • West Reading: Reading Hospital; Contact: 610-988-9323     
  • Wilkes-Barre: Geisinger Wyoming Valley/Henry Cancer Center; Contact: 570-271-5251   
  • Willow Grove: Abington Memorial Hospital-Asplundh Cancer Pavilion; Contact: 215-481-2402
  • Wynnewood: Lankenau Medical Center; Contact: 484-476-2649
  • York: WellSpan Health-York Cancer Center; Contact    877-441-7957        

Rhode Island

  • Providence: Rhode Island Hospital; Contact: 401-444-1488     

South Carolina

  • Anderson: AnMed Health Cancer Center; Contact: 864-512-4651
  • Boiling Springs: Prisma Health Cancer Institute - Spartanburg; Contact : 864-522-2066 
  • Easley: Prisma Health Cancer Institute - Easley; Contact: 864-522-2066  
  • Greenville: Saint Francis Hospital; Contact: 864-603-6213  
  • Greenville: Prisma Health Cancer Institute - Butternut; Contact : 864-522-2066  
  • Greenville: Prisma Health Cancer Institute - Faris; Contact    864-522-2066          
  • Greer: Prisma Health Cancer Institute - Greer; Contact:  864-522-2066  
  • Rock Hill: Levine Cancer Institute-Rock Hill; Contact:  800-804-9376         
  • Seneca: Prisma Health Cancer Institute - Seneca; Contact : 864-522-2066  
  • Spartanburg: Spartanburg Medical Center      

South Dakota

  • Rapid City: Rapid City Regional Hospital; Contact: 605-716-3982  
  • Sioux Falls: Sanford Cancer Center Oncology Clinic; Contact: 605-312-3320  
  • Sioux Falls: Avera Cancer Institute; Contact: 605-322-3095  
  • Sioux Falls: Sanford USD Medical Center - Sioux Falls; Contact: 605-312-3320       


  • Kingsport: Regional Cancer Center at Indian Path Community Hospital; Contact: 423-578-8538  
  • Knoxville: Thompson Cancer Survival Center; Contact: 865-331-1812          
  • Lenoir City: Thompson Oncology Group-Lenoir City; Contact: 865-331-1812     
  • Oak Ridge: Thompson Oncology Group-Oak Ridge; Contact: 865-331-1812     


The Don and Sybil Harrington Cancer Center

Amarillo, Texas, 79106

Contact: Site Public Contact    806-212-1985  

Principal Investigator: Anita Ravipati  


Dell Seton Medical Center at The University of Texas          

Austin, Texas, 78701

Contact: Site Public Contact    512-324-7991     

Principal Investigator: Om N. Pandey 


MD Anderson in The Woodlands      

Conroe, Texas, 77384

Contact: Site Public Contact    866-632-6789  

Principal Investigator: George J. Chang


Parkland Memorial Hospital 

Dallas, Texas, 75235

Contact: Site Public Contact    214-590-5582  

Principal Investigator: Syed M. Kazmi        


UT Southwestern/Simmons Cancer Center-Dallas   

Dallas, Texas, 75390

Contact: Site Public Contact    214-648-7097  

Principal Investigator: Syed M. Kazmi       


M D Anderson Cancer Center

Houston, Texas, 77030

Contact: Site Public Contact    877-632-6789  

Principal Investigator: George J. Chang  


MD Anderson West Houston

Houston, Texas, 77079

Contact: Site Public Contact    877-632-6789  

Principal Investigator: George J. Chang        


MD Anderson League City     

League City, Texas, 77573

Contact: Site Public Contact    877-632-6789  

Principal Investigator: George J. Chang


Scott and White Healthcare Round Rock       Active, not recruiting

Round Rock, Texas, 78665


MD Anderson in Sugar Land  

Sugar Land, Texas, 77478

Contact: Site Public Contact    877-632-6789  

Principal Investigator: George J. Chang      


Scott and White Memorial Hospital  Active, not recruiting

Temple, Texas, 76508



American Fork Hospital / Huntsman Intermountain Cancer Center

American Fork, Utah, 84003

Contact: Site Public Contact    801-855-4100  

Principal Investigator: Ramya Thota      


Sandra L Maxwell Cancer Center      

Cedar City, Utah, 84720

Contact: Site Public Contact    435-868-5680  

Principal Investigator: Ramya Thota     


Farmington Health Center    

Farmington, Utah, 84025

Contact: Site Public Contact    888-424-2100  

Principal Investigator: Glynn W. Gilcrease     


Logan Regional Hospital        

Logan, Utah, 84321

Contact: Site Public Contact    435-716-6400  

Principal Investigator: Ramya Thota   


Utah Valley Regional Medical Center

Provo, Utah, 84604

Contact: Site Public Contact    801-357-7965  

Principal Investigator: Ramya Thota    


Dixie Medical Center Regional Cancer Center          

Saint George, Utah, 84770

Contact: Site Public Contact    435-688-4167  

Principal Investigator: Ramya Thota        


Huntsman Cancer Institute/University of Utah        

Salt Lake City, Utah, 84112

Contact: Site Public Contact    888-424-2100  

Principal Investigator: Glynn W. Gilcrease  



Wellmont Medical Associates-Bristol

Bristol, Virginia, 24201

Contact: Site Public Contact    423-578-8538  

Principal Investigator: Asheesh Shipstone 


University of Virginia Cancer Center 

Charlottesville, Virginia, 22908

Contact: Site Public Contact    434-243-6303  

Principal Investigator: Tri M. Le 


Centra Lynchburg Hematology-Oncology Clinic Inc  

Lynchburg, Virginia, 24501

Contact: Site Public Contact    434-200-5925  

Principal Investigator: Khalid Matin       


Sovah Health Martinsville     

Martinsville, Virginia, 24115

Contact: Site Public Contact    276-666-7489  

Principal Investigator: Mohammed Saad    


Bon Secours Memorial Regional Medical Center     

Mechanicsville, Virginia, 23116

Contact: Site Public Contact    804-893-8611  

Principal Investigator: William J. Irvin  


Bon Secours Saint Francis Medical Center    

Midlothian, Virginia, 23114

Contact: Site Public Contact    804-893-8611  

Principal Investigator: William J. Irvin     


Southwest VA Regional Cancer Center         

Norton, Virginia, 24273

Contact: Site Public Contact    423-578-8538  

Principal Investigator: Asheesh Shipstone   


Bon Secours Saint Mary's Hospital   

Richmond, Virginia, 23226

Contact: Site Public Contact    804-893-8611  

Principal Investigator: William J. Irvin     


Virginia Cancer Institute       

Richmond, Virginia, 23230

Contact: Site Public Contact    804-287-3000  

Principal Investigator: Khalid Matin  


VCU Massey Cancer Center at Stony Point   

Richmond, Virginia, 23235

Contact: Site Public Contact    804-628-1939  

Principal Investigator: Khalid Matin      


Virginia Commonwealth University/Massey Cancer Center

Richmond, Virginia, 23298

Contact: Site Public Contact    804-628-1914  

Principal Investigator: Khalid Matin       


VCU Community Memorial Health Center   

South Hill, Virginia, 23970

Contact: Site Public Contact    434-774-2442  

Principal Investigator: Khalid Matin       


Shenandoah Oncology PC     

Winchester, Virginia, 22601

Contact: Site Public Contact    540-662-1108  

Principal Investigator: Khalid Matin        



Harrison HealthPartners Hematology and Oncology-Bremerton    

Bremerton, Washington, 98310

Contact: Site Public Contact    308-398-6518  

Principal Investigator: Richard L. Deming   


Jefferson Healthcare 

Port Townsend, Washington, 98368

Contact: Site Public Contact    360-344-3091     

Principal Investigator: Nicholas DiBella


Virginia Mason Medical Center         

Seattle, Washington, 98101

Contact: Site Public Contact    206-342-6954  

Principal Investigator: Hagen F. Kennecke


Seattle Cancer Care Alliance 

Seattle, Washington, 98109

Contact: Site Public Contact    800-804-8824     

Principal Investigator: Stacey A. Cohen       


Kaiser Permanente Washington        Active, not recruiting

Seattle, Washington, 98112


Swedish Medical Center-First Hill     

Seattle, Washington, 98122-4307

Contact: Site Public Contact    206-215-3086  

Principal Investigator: Alison K. Conlin      


Seattle Cancer Care Alliance at Northwest Hospital

Seattle, Washington, 98133

Contact: Site Public Contact    206-606-5800     

Principal Investigator: Stacey A. Cohen     


West Virginia

United Hospital Center         

Bridgeport, West Virginia, 26330

Contact: Site Public Contact    304-293-7374  

Principal Investigator: Shalu Pahuja    


West Virginia University Charleston Division

Charleston, West Virginia, 25304

Contact: Site Public Contact    304-388-9944     

Principal Investigator: Steven J. Jubelirer        


Edwards Comprehensive Cancer Center      

Huntington, West Virginia, 25701

Contact: Site Public Contact    304-399-6617     

Principal Investigator: Maria R. Tria Tirona       



Langlade Hospital and Cancer Center

Antigo, Wisconsin, 54409

Contact: Site Public Contact    715-623-9869  

Principal Investigator: Harish G. Ahuja        


ThedaCare Regional Cancer Center  

Appleton, Wisconsin, 54911

Contact: Site Public Contact    920-364-3605  

Principal Investigator: Xin Yao      


Duluth Clinic Ashland

Ashland, Wisconsin, 54806

Contact: Site Public Contact    218-786-3308  

Principal Investigator: Bret E. Friday      


Ascension Southeast Wisconsin Hospital - Elmbrook Campus         

Brookfield, Wisconsin, 53045

Contact: Site Public Contact    414-635-6420  

Principal Investigator: Francis J. Cuevas   


Aurora Cancer Care-Southern Lakes VLCC    

Burlington, Wisconsin, 53105

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel  


Marshfield Medical Center-EC Cancer Center          

Eau Claire, Wisconsin, 54701

Contact: Site Public Contact    800-782-8581  

Principal Investigator: Isaac K. Yeboah      


Mayo Clinic Health System-Eau Claire Clinic

Eau Claire, Wisconsin, 54701

Contact: Site Public Contact    855-776-0015     

Principal Investigator: Frank A. Sinicrope


Aurora Health Center-Fond du Lac   

Fond Du Lac, Wisconsin, 54937

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel    


Ascension Saint Francis - Reiman Cancer Center      

Franklin, Wisconsin, 53132

Contact: Site Public Contact    414-635-6420  

Principal Investigator: Francis J. Cuevas   


Aurora Health Care Germantown Health Center     

Germantown, Wisconsin, 53022

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel   


Aurora Cancer Care-Grafton 

Grafton, Wisconsin, 53024

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel     


Saint Vincent Hospital Cancer Center Green Bay      

Green Bay, Wisconsin, 54301

Contact: Site Public Contact    920-433-8889  

Principal Investigator: Anthony J. Jaslowski  


Saint Vincent Hospital Cancer Center at Saint Mary's          

Green Bay, Wisconsin, 54303

Contact: Site Public Contact    920-433-8889  

Principal Investigator: Anthony J. Jaslowski     


Aurora BayCare Medical Center        

Green Bay, Wisconsin, 54311

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel   


Aurora Cancer Care-Kenosha South 

Kenosha, Wisconsin, 53142

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel     


Gundersen Lutheran Medical Center

La Crosse, Wisconsin, 54601

Contact: Site Public Contact    608-775-2385  

Principal Investigator: Michael O. Ojelabi        


Mayo Clinic Health System-Franciscan Healthcare  

La Crosse, Wisconsin, 54601

Contact: Site Public Contact    855-776-0015     

Principal Investigator: Frank A. Sinicrope  


Aurora Bay Area Medical Group-Marinette 

Marinette, Wisconsin, 54143

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel       


Marshfield Medical Center-Marshfield        

Marshfield, Wisconsin, 54449

Contact: Site Public Contact    800-782-8581  

Principal Investigator: Isaac K. Yeboah       


Aspirus Medford Hospital     

Medford, Wisconsin, 54451

Contact: Site Public Contact    715-847-2353  

Principal Investigator: Harish G. Ahuja    


Aurora Cancer Care-Milwaukee        

Milwaukee, Wisconsin, 53209

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel     


Aurora Saint Luke's Medical Center  

Milwaukee, Wisconsin, 53215

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel    


Medical College of Wisconsin

Milwaukee, Wisconsin, 53226

Contact: Site Public Contact    414-805-3666     

Principal Investigator: James P. Thomas  


Aurora Sinai Medical Center 

Milwaukee, Wisconsin, 53233

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel   


Marshfield Clinic-Minocqua Center  

Minocqua, Wisconsin, 54548

Contact: Site Public Contact    800-782-8581  

Principal Investigator: Isaac K. Yeboah  


ProHealth D N Greenwald Center     

Mukwonago, Wisconsin, 53149

Contact: Site Public Contact  

Principal Investigator: Timothy R. Wassenaar  


Cancer Center of Western Wisconsin

New Richmond, Wisconsin, 54017

Contact: Site Public Contact    952-993-1517  

Principal Investigator: Daniel M. Anderson      


ProHealth Oconomowoc Memorial Hospital

Oconomowoc, Wisconsin, 53066

Contact: Site Public Contact    262-928-7878     

Principal Investigator: Timothy R. Wassenaar 


Saint Vincent Hospital Cancer Center at Oconto Falls          

Oconto Falls, Wisconsin, 54154

Contact: Site Public Contact    920-433-8889  

Principal Investigator: Anthony J. Jaslowski     


Vince Lombardi Cancer Clinic - Oshkosh       

Oshkosh, Wisconsin, 54904

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel 


Ascension All Saints Hospital

Racine, Wisconsin, 53405

Contact: Site Public Contact    414-635-6420  

Principal Investigator: Francis J. Cuevas


Aurora Cancer Care-Racine   

Racine, Wisconsin, 53406

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel    


Vince Lombardi Cancer Clinic-Sheboygan    

Sheboygan, Wisconsin, 53081

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel      


Marshfield Clinic Stevens Point Center         

Stevens Point, Wisconsin, 54482

Contact: Site Public Contact    800-782-8581  

Principal Investigator: Isaac K. Yeboah    


Saint Vincent Hospital Cancer Center at Sturgeon Bay         

Sturgeon Bay, Wisconsin, 54235-1495

Contact: Site Public Contact    920-433-8889  

Principal Investigator: Anthony J. Jaslowski   


Aurora Medical Center in Summit    

Summit, Wisconsin, 53066

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel    


Vince Lombardi Cancer Clinic-Two Rivers     

Two Rivers, Wisconsin, 54241

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel        


ProHealth Waukesha Memorial Hospital     

Waukesha, Wisconsin, 53188

Contact: Site Public Contact    262-928-7632      

Principal Investigator: Timothy R. Wassenaar


UW Cancer Center at ProHealth Care

Waukesha, Wisconsin, 53188

Contact: Site Public Contact    262-928-5539  

Principal Investigator: Timothy R. Wassenaar    


Aspirus Regional Cancer Center        

Wausau, Wisconsin, 54401

Contact: Site Public Contact    877-405-6866     

Principal Investigator: Harish G. Ahuja      


Ascension Medical Group Southeast Wisconsin - Mayfair Road      

Wauwatosa, Wisconsin, 53226

Contact: Site Public Contact    414-635-6420  

Principal Investigator: Francis J. Cuevas      


Aurora Cancer Care-Milwaukee West           

Wauwatosa, Wisconsin, 53226

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel    


Aurora West Allis Medical Center     

West Allis, Wisconsin, 53227

Contact: Site Public Contact    414-302-2304  

Principal Investigator: Adam P. Siegel     


Marshfield Clinic - Weston Center    

Weston, Wisconsin, 54476

Contact: Site Public Contact    800-782-8581  


Aspirus UW Cancer Center    

Wisconsin Rapids, Wisconsin, 54494

Contact: Site Public Contact    715-422-7718     



This Study is Open To:

Men or women age 18 years or older can participate if they:  

  • Have III colon cancer; tumors must originate in the colon
  • Are patients having a in an MMR gene (, , , , );
  • Have deficient (d) mismatch repair ()
  • Show no evidence of spread to or disease
  • Have had no prior medical therapy (chemotherapy, , biologic or ) or radiation therapy for the current colon cancer except for one cycle of mFOLFOX6
  • Do not have active known autoimmune disease, including colitis, inflammatory bowel disease, rheumatoid arthritis, panhypopituitarism, adrenal insufficiency
  • Do not have active hepatitis B or C
This Study is Not Open To:

Patients will be excluded if they:  

  • Have active pulmonary disease with hypoxia (low oxygen levels)
  • Are not or
  • Women who are pregnant