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Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair
Study Contact Information:
For additional information, please contact: Principal Investigator: Frank A Sinicrope, Alliance for Clinical Trials in Oncology
Glossary on
off
About the Study
may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
This phase III trial is for people with 3 colon cancer. The study will compare how well treatment with a combination of chemotherapy agents and an immunotherapy agent works compared with treatment with combination chemotherapy agents alone. This study is focused on patients who have a known as or , which are commonly seen in people with . NOTE: This study is no longer enrolling people.
This Study is Open To:
Men or women age 18 years or older can participate if they:
- Have stage III colon cancer; tumors must originate in the colon
- Are Lynch syndrome patients having a in an MMR gene (, , , , );
- Have deficient (d) mismatch repair (dMMR)
- Show no evidence of spread to or disease
- Have had no prior medical therapy (chemotherapy, immunotherapy, biologic or ) or radiation therapy for the current colon cancer except for one cycle of mFOLFOX6
- Do not have active known autoimmune disease, including colitis, inflammatory bowel disease, rheumatoid arthritis, panhypopituitarism, adrenal insufficiency
- Do not have active hepatitis B or C
This Study is NOT Open To:
Patients will be excluded if they:
- Have active pulmonary disease with hypoxia (low oxygen levels)
- Are not MSI-High or dMMR
- Women who are pregnant
What the Study Involves
People will be assigned randomly to one of two groups:
Group 1: Chemotherapy and immunotherapy
- People in this group will receive combination chemotherapy intravenously (oxaliplatin, leucovorin calcium and fluorouracil) on day 1, then continuously over 46 hours on days 1-3. Treatment repeats every 14 days for up to 12 cycles in the absence of disease progression or unacceptable .
- Patients also receive atezolizumab IV starting on day 1 of cycle 1 or 2. Treatment repeats every 14 days for up to 25 cycles in the absence of disease progression or unacceptable toxicity.
Group 2: Chemotherapy only
- People in this group will receive combination chemotherapy intravenously (oxaliplatin, leucovorin calcium, and fluorouracil) on day 1, then continuously over 46 hours on days 1-3. Treatment repeats every 14 days for up to 12 cycles in the absence of disease progression or unacceptable toxicity.
Both groups of participants will be followed for up to 5 years.
Study Sites
- Anchorage: Katmai Oncology Group; Contact: 907-212-6871 or email
- Tucson: Banner University Medical Center - Tucson; Contact by email
- Tucson: University of Arizona Cancer Center-North Campus; Contact: 800-327-2873
- Anaheim: Kaiser Permanente-Anaheim; Contact: 800-398-3996 or email
- Arroyo Grande: PCR Oncology; Contact: 702-384-0013 or email
- Auburn: Sutter Auburn Faith Hospital; Contact: 415-209-2686 or email
- Baldwin Park: Kaiser Permanente-Baldwin Park;Contact: 800-398-3996 or email
- Bellflower: Kaiser Permanente-Bellflower; Contact: 800-398-3996 or email
- Berkeley: Alta Bates Summit Medical Center-Herrick Campus; Contact: 415-209-2686 or email
- Clovis: University Oncology Associates; Contact: 559-256-9680
- Dublin: Epic Care-Dublin; Contact: 925-875-1677
- Emeryville: Epic Care Partners in Cancer Care; Contact: 510-629-6682
- Fontana: Kaiser Permanente-Fontana; Contact: 800-398-3996 or email
- Fremont: Palo Alto Medical Foundation-Fremont; Contact by email
- Harbor City: Kaiser Permanente - Harbor City; Contact: 800-398-3996 or email
- Irvine: Kaiser Permanente-Irvine; Contact: 800-398-3996 or or email
- Los Angeles:Kaiser Permanente Los Angeles Medical Center; Contact: 800-398-3996 or email
- Los Angeles County-USC Medical Center; Contact: 323-865-0451
- Los Angeles: USC / Norris Comprehensive Cancer Center; Contact: 323-865-0451
- Los Angeles: Kaiser Permanente-Cadillac; Contact: 800-398-3996 or email
- Martinez: Contra Costa Regional Medical Center; Contact: 925-957-5400
- Marysville: Fremont - Rideout Cancer Center; Contact: 530-749-4400
- Modesto: Memorial Medical Center; Contact: 415-209-2686 or email
- Mountain View: Palo Alto Medical Foundation-Camino Division; Contact: 415-209-2686 or email
- Ontario: Kaiser Permanente-Ontario; Contact: 800-398-3996 or email
- Orange: UC Irvine Health/Chao Family Comprehensive Cancer Center; Contact: 877-827-8839 or email
- Palo Alto: Palo Alto Medical Foundation Health Care; Contact: 415-209-2686 or email
- Palo Alto: Stanford Cancer Institute Palo Alto; Contact: 650-498-7061 or email
- Palo Alto: VA Palo Alto Health Care System; Contact: 800-455-0057
- Panorama City: Kaiser Permanente - Panorama City; Contact: 800-398-3996 or email
- Riverside: Kaiser Permanente - Riverside; Contact: 800-398-3996 or email
- Roseville: Sutter Roseville Medical Center; Contact: 415-209-2686 or email
- Sacramento: Sutter Medical Center Sacramento; Contact: 415-209-2686 or email
- Sacramento: University of California Davis Comprehensive Cancer Center; Contact: 916-734-3089
- Salinas: Salinas Valley Memorial; Contact: 831-759-1838 or email
- San Diego: Kaiser Permanente-San Diego Zion; Contact: 800-398-3996 or email
- San Diego: Sharp Memorial Hospital; Contact: 858-939-5062 or email
- San Francisco: California Pacific Medical Center-Pacific Campus; Contact: 415-209-2686 or email
- San Marcos: Kaiser Permanente-San Marcos; Contact: 800-398-3996 or email
- Santa Cruz: Palo Alto Medical Foundation-Santa Cruz; Contact: Site Public Contact: 415-209-2686 or email
- Sunnyvale: Palo Alto Medical Foundation-Sunnyvale; Contact: Site Public Contact: 415-209-2686 or email
- Vellego: Sutter Solano Medical Center/Cancer Center; Contact: Site Public Contact: 415-209-2686 or email
- Woodland Hills: Kaiser Permanente-Woodland Hills; Contact: 800-398-3996 or email
- Aurora: Rocky Mountain Cancer Centers-Aurora; Contact: 303-777-2663 or email
- Aurora: University of Colorado Hospital; Contact:720-848-0650
- Boulder: Boulder Community Hospital; Contact 303-777-2663 or email
- Boulder: Rocky Mountain Cancer Centers-Boulder; Contact 303-777-2663 or email
- Colorado Springs: Penrose-Saint Francis Healthcare; Contact: 308-398-6518 or email
- Colorado Springs: UCHealth Memorial Hospital Central; Contact: 719-365-2406
- Colorado Springs: Memorial Hospital North; Contact: 719-364-6700
- Denver: Kaiser Permanente-Franklin; Contact: 303-764-5056 or email
- Denver: National Jewish Health-Main Campus; Contact: 877-225-5654 or email
- Denver: Rocky Mountain Cancer Centers-Midtown; Contact: 303-777-2663 or email
- Denver: SCL Health Saint Joseph Hospital; Contact: 303-777-2663 or email
- Denver: Rocky Mountain Cancer Centers-Rose; Contact: 303-777-2663 or email
- Englewood: Swedish Medical Center; Contact: 303-777-2663 or email
- Englewood: Mountain Blue Cancer Care Center - Swedish; Contact: 303-777-2663 or email
- Fort Collins: Poudre Valley Hospital; Contact: 970-297-6150
- Fort Collins: Cancer Care and Hematology-Fort Collins; Contact: 888-823-5923 or email
- Golden: National Jewish Health-Western Hematology Oncology; Contact: 303-777-2663 or email
- Grand Junction:Saint Mary's Hospital and Regional Medical Center; Contact: 303-777-2663 or email
- Greeley: North Colorado Medical Center; Contact: 303-777-2663 or email
- Greeley: UCHealth Greeley Hospital;Contact: 888-823-5923 or email
- Lafayette: Good Samaritan Medical Center; Contact: 303-673-1622
- Lafayette: Kaiser Permanente-Rock Creek; Contact: 303-764-5056 or email
- Littleton: Rocky Mountain Cancer Centers-Littleton; Contact: 303-777-2663 or email
- Lone Tree: Kaiser Permanente-Lone Tree; Contact: 303-764-5056 or email
- Lone Tree: Rocky Mountain Cancer Centers-Sky Ridge; Contact: 303-777-2663 or email
- Longmont: Longmont United Hospital; Contact: 308-398-6518 or email
- Loveland: Medical Center of the Rockies; Contact: 970-203-7083
- Loveland: McKee Medical Center; Contact: 303-777-2663 or email
- Thornton: National Jewish Health-Northern Hematology Oncology; Contact: 303-777-2663 or email
- Wheat Ridge: SCL Health Lutheran Medical Center; Contact: 303-777-2663 or email
- Derby: Smilow Cancer Hospital-Derby Care Center; Contact: 203-785-5702 or email
- Fairfield: Smilow Cancer Hospital Care Center-Fairfield; Contact: 203-785-5702 or email
- Guildford: Smilow Cancer Hospital Care Center - Guiford; Contact: 203-785-5702 or email
- Hartford: Smilow Cancer Hospital Care Center at Saint Francis; Contact: 203-785-5702 or email
- Middletown: Middlesex Hospital; Contact: 860-358-2058 or email
- New Haven: Yale University; Contact: 203-785-5702 or email
- North Haven: Yale-New Haven Hospital North Haven Medical Center; Contact: 203-785-5702 or email
- Torrington: Smilow Cancer Hospital-Torrington Care Center ;Contact: 203-785-5702 or email
- Trumbull: Smilow Cancer Hospital Care Center-Trumbull; Contact: 203-785-5702 or email
- Waterbury: Smilow Cancer Hospital-Waterbury Care Center; Contact: 203-785-5702 or email
- Waterford: Smilow Cancer Hospital-Waterford Care Center; Contact: 203-785-5702 or email
- Frankford: Beebe South Coastal Health Campus; Contact: 302-645-3100 or email
- Newark: Helen F Graham Cancer Center; Contact: 302-623-4450 or email
- Newark: Medical Oncology Hematology Consultants PA; Contact: 302-623-4450 or email
- Rehoboth Beach: Beebe Health Campus; Contact: 302-645-3100 or email
- Sibley Memorial Hospital; Contact: 202-243-2373 or email
- Aventura: Mount Sinai Comprehensive Cancer Center at Aventura; Contact: 305-674-2625 or email
- Daytona Beach: Halifax Health Medical Center-Centers for Oncology; Contact: 386-254-4211
- Fort Lauderdale: Broward Health Medical Center; Contact: 954-355-5346
- Fort Myers: Regional Cancer Center-Lee Memorial Health System; Contact: 773-702-9171 or email
- Miami Beach: Mount Sinai Medical Center; Contact:305-674-2625 or email
- Orlando: AdventHealth Orlando; Contact: 407-303-2090 or email
- Albany: Phoebe Putney Memorial Hospital Contact: 229-312-0405 or email
- Athens: University Cancer and Blood Center LLC; Contact: 706-353-5006 or email
- Augusta: Augusta Oncology Associates PC-D'Antignac; Contact: 706-821-2944
- Augusta: Augusta Oncology Associates PC-Wheeler; Contact: 706-736-1830
- 'Aiea: Pali Momi Medical Center; Contact: 808-486-6000
- Honolulu: Queen's Cancer Cenrer - POB I; Contact: 808-532-0315
- Honolulu: Queen's Medical Center; Contact: 808-545-8548
- Honolulu: Straub Clinic and Hospital; Contact: 808-522-4333
- Honolulu: Queen's Cancer Center - Kuakini; Contact: 808-531-8521
- Boise: Saint Alphonsus Cancer Care Center-Boise; Contact: 734-712-3671 or email
- Boise: Saint Luke's Mountain States Tumor Institute; Contact: 208-381-2774 or email
- Caldwell: Saint Alphonsus Cancer Care Center-Caldwell; Contact: 734-712-3671 or email
- Coeur d'Alene: Kootenai Medical Center; Contact: 406-969-6060 or email
- Fruitland: Saint Luke's Cancer Institute - Fruitland; Contact: 208-381-2774 or email
- Meridian: Saint Luke's Cancer Institute - Meridian; Contact: 208-381-2774 or email
- Nampa: Saint Alphonsus Medical Center-Nampa; Contact: 734-712-3671 or email
- Nampa: Saint Luke's Cancer Institute - Nampa; Contact: 208-381-2774 or email
- Post Falls: Kootenai Cancer Center; Contact: 406-969-6060 or email
- Sandpoint: Kootenai Cancer Center; Contact: 406-969-6060 or email
- Twin Falls:Saint Luke's Cancer Institute - Twin Falls; Contact: 208-381-2774 or email
- Bloomington: Illinois CancerCare-Bloomington; Contact: 309-243-3605 or email
- Canton: Illinois CancerCare-Canton; Contact: 309-243-3605 or email
- Carterville: SIH Cancer Institute; Contact: 618-985-3333 or email
- Carthage: Illinois CancerCare-Carthage; Contact: 309-243-3605 or email
- Centralia: Centralia Oncology Clinic; Contact: 217-876-4740 or email
- Chicago: Northwestern University; Contact: 312-695-1301 or email
- Chicago: Rush University Medical Center; Contact : 312-942-5498 or email
- Crystal Lake: AMG Crystal Lake - Oncology; Contact: Site Public Contact 630-929-6129 or email
- Decatur: Cancer Care Specialists of Illinois - Decatur; Contact: 217-876-4740 or email
- Dixon: Illinois CancerCare-Dixon; Contact 815-285-7800
- Eureka: Illinois CancerCare-Eureka; Contact 309-243-3605 or email
- Evanston: NorthShore University HealthSystem-Evanston Hospital; Contact: 847-570-2109
- Freeport: Freeport Memorial Hospital/Leonard C Ferguson Cancer Center; Contact: 815-599-7000
- Galesburg: Illinois CancerCare-Galesburg; Contact: 309-243-3605 andersonj@illinoiscancercare.com
- Geneva: Northwestern Medicine Cancer Center Delnor; Contact: 630-352-5360 Donald.Smith3@nm.org
- Glenview: NorthShore University HealthSystem-Glenbrook Hospital; Contact: 847-570-2109
- Harvey:Ingalls Memorial Hospital; Contact: 708-915-4673 clinicaltrials@ingalls.org
- Highland Park: NorthShore University HealthSystem-Highland Park Hospital: Contact: 847-570-2109
- Kewanee: Illinois CancerCare-Kewanee Clinic; Contact: 309-243-3605 andersonj@illinoiscancercare.com
- Lake Forest: Northwestern Medicine Lake Forest Hospital: Contact: cancertrials@northwestern.edu
- Libertyville: AMG Libertyville - Oncology; Contact: 630-929-6129 advocateresearch@advocatehealth.com
- Macomb: Illinois CancerCare-Macomb; Contact: 309-243-3605 andersonj@illinoiscancercare.com
- Maywood: Loyola University Medical Center; Contact: 708-226-4357
- Mount Vernon: Good Samaritan Regional Health Center; Contact: 618-242-4600
- O'Fallon: Cancer Care Center of O'Fallon; Contact 217-876-4762 morganthaler.jodi@mhsil.com
- Ottawa: Illinois CancerCare-Ottawa Clinic; Contact: 309-243-3605 andersonj@illinoiscancercare.com
- Park Ridge: Advocate Lutheran General Hospital; Contact: 847-384-3621
- Pekin: Illinois CancerCare-Pekin; Contact: 309-243-3605 andersonj@illinoiscancercare.com
- Peoria: Illinois CancerCare-Peoria; Contact: 309-243-3605 andersonj@illinoiscancercare.com
- Peru: Illinois CancerCare-Peru; Contact: 309-243-3605 andersonj@illinoiscancercare.com
- Princeton: Illinois CancerCare-Princeton; Contact: 309-243-3605 andersonj@illinoiscancercare.com
- Silvis: Genesis Cancer Center - Silvis; Contact: 563-421-1908 turnerk@genesishealth.com
- Springfield: Southern Illinois University School of Medicine; Contact: 217-545-7929
- Springfield: Springfield Clinic; Contact: 800-444-7541
- Warrenville: Northwestern Medicine Cancer Center Warrenville; Contact: 630-352-5360 Donald.Smith3@nm.org
- Indianapolis: Indiana University/Melvin and Bren Simon Cancer Center; Contact: 317-278-5632 iutrials@iu.edu
- Indianapolis: Sidney and Lois Eskenazi Hospital Contact 317-278-5632 iutrials@iu.edu
- Indianapolis: Franciscan Health Indianapolis; Contact: 317-528-7060
- Mooresville: Franciscan Health Mooresville; Contact: 317-834-3603
- Richmond: Reid Health; Contact: 937-528-2900 clinical.trials@daytonncorp.org
- Terre Haute: Union Hospital; Contact: 812-238-7394
- Ames: Mary Greeley Medical Center; Contact: 515-956-4132
- Ames: McFarland Clinic PC - Ames; Contact: 515-239-4734 ksoder@mcfarlandclinic.com
- Bettendorf: University of Iowa Healthcare Cancer Services Quad Cities; Contact: 563-355-7733 kedaprile@rccqc.com
- Boone: McFarland Clinic PC-Boone; Contact: 515-956-4132
- Cedar Rapids: Mercy Hospital; Contact: 319-365-4673
- Cedar Rapids: Oncology Associates at Mercy Medical Center; Contact 319-363-2690
- Clive: Medical Oncology and Hematology Associates-West Des Moines; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Clive: Mercy Cancer Center-West Lakes; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Davenport: Genesis Medical Center - East Campus; Contact: 563-421-1908 turnerk@genesishealth.com
- Davenport: Iowa Cancer Specialists; Contact: 563-421-1908 turnerk@genesishealth.com
- Des Moines: Iowa Methodist Medical Center; Contact: 515-241-6727
- Des Moines: Medical Oncology and Hematology Associates-Des Moines; Contact: 515-282-2921
- Des Moines: Broadlawns Medical Center; Contact: 515-282-2200
- Des Moines: Medical Oncology and Hematology Associates-Laurel; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Des Moines: Mercy Medical Center - Des Moines; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Fort Dodge: McFarland Clinic PC-Trinity Cancer Center; Contact : 515-956-4132
- Iowa City: University of Iowa/Holden Comprehensive Cancer Center; Contact: 800-237-1225
- Jefferson: McFarland Clinic PC-Jefferson; Contact: 515-956-4132
- Marshalltown: McFarland Clinic PC-Marshalltown; Contact: 515-956-4132
- Sioux City: Siouxland Regional Cancer Center; Contact: 712-252-9326 HoopingarnerT@jencc.com
- West Des Moines: Mercy Medical Center-West Lakes; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Hays: HaysMed University of Kansas Health System
- Kansas City:University of Kansas Cancer Center-West; Contact: 913-588-3671 or email
- Liberal: Cancer Center of Kansas-Liberal; Contact: 316-268-5374 or email
- Olathe: Olathe Health Cancer Center; Contact: 913-355-8000 Jeni.wakefield@olathehealth.org
- Overland Park: University of Kansas Cancer Center-Overland Park; Contact: 913-588-3671 KUCC_Navigation@kumc.edu
- Pittsburg: Ascension Via Christi - Pittsburg; Contact: 620-235-7900 jennifer.jameson@ascension.org
- Salina: Salina Regional Health Center; Contact: 785-452-7038 mleepers@srhc.com
- Topeka: University of Kansas Health System Saint Francis Campus; Contact: 785-295-8000
- Westwood: University of Kansas Hospital-Westwood Cancer Center; Contact: 913-588-3671 KUCC_Navigation@kumc.edu
- Wichita: Cancer Center of Kansas-Wichita Medical Arts Tower; Contact: 316-268-5374 Keisha.humphries@ascension.org
- Edgewood: Saint Elizabeth Medical Center South; Contact: 859-301-5473 darla.hehman@stelizabeth.com
- Fort Thomas: Saint Elizabeth Fort Thomas; Contact 859-301-9418
- Lexington: Baptist Health Lexington; Contact: 859-260-6425
- Lexington: Saint Joseph Hospital East; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Lexington: University of Kentucky/Markey Cancer Center; Contact: 859-257-3379
- Baton Rouge: LSU Health Baton Rouge-North Clinic; Contact: 225-215-1353 clinicalresearch@marybird.com
- Baton Rouge: Louisiana Hematology Oncology Associates LLC; Contact: 225-215-1353 clinicalresearch@marybird.com
- Baton Rouge: Mary Bird Perkins Cancer Center; Contact: 225-215-1353 clinicalresearch@marybird.com
- Baton Rouge: Our Lady of the Lake - Medical Oncology; Contact: 225-215-1353 clinicalresearch@marybird.com
- Kenner: Ochsner Medical Center Kenner; Contact: 504-464-8314 cris.molina@ochsner.org
- New Orleans: Ochsner Medical Center Jefferson; Contact: 504-703-8712 Gregory.Johnstone@ochsner.org
- Augusta: Harold Alfond Center for Cancer Care; Contact: 207-626-4855
- Belfast: Waldo County General Hospital; Contact: 207-338-2500
- Biddeford: MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford; Contact LLemire@mmc.org
- Brewer: Lafayette Family Cancer Center-EMMC; Contact: 800-987-3005
- Rockport: Penobscot Bay Medical Center; Contact: 207-396-8670 ClinicalResearch@mmc.org
- Sanford: MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford; Contact LLemire@mmc.org
- South Portland: Maine Medical Partners - South Portland; Contact: 207-396-8670 ClinicalResearch@mmc.org
- Baltimore: Saint Agnes Hospital; Contact: 410-368-2910
- Baltimore: Johns Hopkins University/Sidney Kimmel Cancer Center; Contact: 410-955-8804 jhcccro@jhmi.edu
- Glen Burnie: UM Baltimore Washington Medical Center/Tate Cancer Center; Contact: 410-553-8100
- Boston: Boston Medical Center; Contact: 617-638-8265
- Boston: Beth Israel Deaconess Medical Center; Contact: 617-667-9925
- Boston: Dana-Farber Cancer Institute; Contact: 877-442-3324
- Ann Arbor: Saint Joseph Mercy Hospital; Contact: 734-712-3671 stephanie.couch@stjoeshealth.org
- Battle Creek: Bronson Battle Creek; Contact: 616-391-1230 crcwm-regulatory@crcwm.org
- Bay City: McLaren Cancer Institute-Bay City; Contact: 313-576-9790 ctoadmin@karmanos.org
- Bloomfield: McLaren Cancer Institute-Bloomfield; Contact: 313-576-9790 ctoadmin@karmanos.org
- Brighton: IHA Hematology Oncology Consultants-Brighton; Contact: 734-712-3671 stephanie.couch@stjoeshealth.org
- Brighton: Saint Joseph Mercy Brighton; Contact: 734-712-3671 stephanie.couch@stjoeshealth.org
- Brownstown: Henry Ford Cancer Institute-Downriver; Contact: 313-916-3721 CTOResearch@hfhs.org
- Canton: IHA Hematology Oncology Consultants-Canton; Contact: 734-712-3671 stephanie.couch@stjoeshealth.org
- Canton: Saint Joseph Mercy Canton; Contact: 734-712-3671 stephanie.couch@stjoeshealth.org
- Chelsea: IHA Hematology Oncology Consultants-Chelsea; Contact: 734-712-3671 or email
- Chelsea: Saint Joseph Mercy Chelsea; Contact: 734-712-3671 or email
- Clarkston: Hematology Oncology Consultants-Clarkston; Contact: 734-712-3671 or email
- Clarkston: McLaren Cancer Institute-Clarkston; Contact: 313-576-9790 or email
- Dearborn: Beaumont Hospital-Dearborn; Contact: 248-551-7695
- Dearborn: Henry Ford Medical Center-Fairlane; Contact: 313-916-3721 or email
- Detroit:Wayne State University/Karmanos Cancer Institute; Contact: 313-576-9790 or email
- Detroit: Henry Ford Hospital; Contact: 313-916-3721 or email
- East China Township: Great Lakes Cancer Management Specialiists - Doctors Park; Contact: 734-712-3671 or email
- Farmington Hills: Weisberg Cancer Treatment Center; Contact: 313-576-9790 or email
- Flint: McLaren Cancer Institute-Flint; ; Contact: 313-576-9790 or by email
- Flint: Genessee Cancer and Blood Disease Center: Contact: 734-712-3671 or email
- Flint: Singh and Arora Hematology Oncology PC; Contact: 313-576-9790 or email
- Grand Rapids: Spectrum Health at Butterworth Campus; Contact: 616-391-1230 or email
- Grosse Point Woods: Academic Hematology Oncology Specialists; Contact: 734-712-3671 or email
- Grosse Point Woods: Great Lakes Cancer Management Specialists-Van Elslander Cancer Center; Contact: 734-712-3671 or email
- Jackson: Allegiance Health; Contact: 313-916-3721 or by email
- Kalamazoo: West Michigan Cancer Center; Contact: 616-391-1230 or email
- Lansing: McLaren-Greater Lansing; Contact: 313-576-9790 or email
- Lansing: Sparrow Hospital; Contact: 734-712-3671 or email
- Lapeer: McLaren Cancer Institute-Lapeer Region; Contact: 313-576-9790 or email
- Livonia: Hope Cancer Clinic; Contact: 734-712-3671 or email
- Livonia: Saint Mary Mercy Hospital; Contact: 734-712-3671 or email
- Mount Clemens: McLaren Cancer Institute-Macomb; Contact: 313-576-9790 or email
- Mount Pleasant: McLaren Cancer Institute-Central Michigan; Contact: 313-576-9790 or email
- Novi: Henry Ford Medical Center-Columbus; Contact: 313-916-3721 or by email
- Petoskey: McLaren Cancer Institute-Northern Michigan; Contact: 313-576-9790 or email
- Pontiac: Saint Joseph Mercy Oakland; Contact: 734-712-3671 or email
- Port Huron: McLaren-Port Huron; Contact: 313-576-9790 or email
- Royal Oak: William Beaumont Hospital-Royal Oak; Contact: 248-551-7695
- Saginaw: Ascension Saint Mary's Hospital; Contact: 734-712-3671 or email
- Southfield: Ascension Providence Hospitals - Southfield; Contact: 248-849-5332 or email
- Tawas City: Ascension Saint Joseph Hospital; Contact: 734-712-3671 or email
- Traverse City: Munson Medical Center; Contact: 616-391-1230 or email
- Troy: William Beaumont Hospital-Troy; Contact: 248-551-7695
- Warren: Great Lakes Cancer Management Specialists-Macomb Professional Building; Contact: 734-712-3671 or email
- West Bloomfield: Henry Ford West Bloomfield Hospital; Contact: 313-916-3721 or by email
- West Branch: Saint Mary's Oncology/Hematology Associates of West Branch; Contact: 734-712-3671 or email
- Ypsilanti: IHA Hematology Oncology Consultants-Ann Arbor; Contact: 734-712-3671 or email
- Albert Lea: Mayo Clinic Health System in Albert Lea; Contact: 855-776-0015
- Bemidji: Sanford Joe Lueken Cancer Center; Contact: 218-333-5000 OncologyClinicalTrialsFargo@sanfordhealth.org
- Burnsville: Fairview Ridges Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Coon Rapids: Mercy Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Deer River: Essentia Health - Deer River Clinic; Contact: 218-786-3308 CancerTrials@EssentiaHealth.org
- Duluth: Essentia Health Cancer Center; Contact: 218-786-3308 CancerTrials@EssentiaHealth.org
- Edina: Fairview Southdale Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Fridley: Unity Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Hibbing: Essentia Health Hibbing Clinic; Contact: 218-786-3308
- Mankato: Mayo Clinic Health Systems-Mankato; Contact: 855-776-0015
- Maplewood: Minnesota Oncology Hematology PA-Maplewood; Contact: 952-993-1517 mmcorc@healthpartners.com
- Maplewood: Saint John's Hospital - Healtheast; Contact: 952-993-1517 mmcorc@healthpartners.com
- Minneapolis: Abbott-Northwestern Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Minneapolis: Hennepin County Medical Center; Contact: 952-993-1517 mmcorc@healthpartners.com
- Minneapolis: Health Partners; Contact: 952-993-1517 mmcorc@healthpartners.com
- Rochester: Mayo Clinic in Rochester; Contact: 855-776-0015
- Saint Cloud: Coborn Cancer Center at Saint Cloud Hospital; Contact: 877-229-4907 coborncancercenter@centracare.com
- Saint Louis Park: Park Nicollet Clinic - Saint Louis Park; Contact: 952-993-1517 mmcorc@healthpartners.com
- Saint Paul: Regions Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Saint Paul: United Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Sandstone: Essentia Health Sandstone; Contact 218-786-3308 CancerTrials@EssentiaHealth.org
- Stillwater: Lakeview Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Virginia: Essentia Health Virginia Clinic; Contact: 218-786-3308 CancerTrials@EssentiaHealth.org
- Waconia: Ridgeview Medical Center; Waconia, Minnesota, 55387
- Wilmar: Rice Memorial Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Woodbury: Minnesota Oncology Hematology PA-Woodbury; Contact: 952-993-1517 mmcorc@healthpartners.com
- Ballwin: Saint Louis Cancer and Breast Institute-Ballwin; Contact: 314-251-7058
- Cape Girardeau: Saint Francis Medical Center; Contact: 573-334-2230 sfmc@sfmc.net
- Cape Girardeau: Southeast Cancer Center; Contact: 573-651-5550
- Columbia: University of Missouri - Ellis Fischel; Contact: 573-882-7440
- Creve Coeur: Siteman Cancer Center at West County Hospital; Contact: 800-600-3606 info@siteman.wustl.edu
- Joplin: Mercy Hospital Joplin; Contact: 417-556-3074 esmeralda.carrillo@mercy.net
- Kansas City: Truman Medical Centers; Contact: 816-404-4375
- Kansas City: University of Kansas Cancer Center - North; Contact: 913-588-3671 KUCC_Navigation@kumc.edu
- Lee's Summit: University of Kansas Cancer Center - Lee's Summit; Contact: 913-588-3671 KUCC_Navigation@kumc.edu
- Saint Louis: Washington University School of Medicine; Contact: 800-600-3606 info@siteman.wustl.edu
- Saint Louis: Siteman Cancer Center-South County; Contact: 800-600-3606 info@siteman.wustl.edu
- Saint Louis: Missouri Baptist Medical Center; Contact: 314-996-5569
- Saint Louis: Siteman Cancer Center at Christian Hospital; Contact: 800-600-3606 info@siteman.wustl.edu
- Saint Peters: Siteman Cancer Center at Saint Peters Hospital; Contact: 800-600-3606 info@siteman.wustl.edu
- Sainte Genevieve: Sainte Genevieve County Memorial Hospital; Contact: 314-996-5569
- Springfield: Mercy Hospital Springfield; Contact: 417-269-4520
- Sullivan: Missouri Baptist Sullivan Hospital; Contact: 314-996-5569
- Sunset Hills: Missouri Baptist Outpatient Center-Sunset Hills; Contact: 314-996-5569
- Anaconda: Community Hospital of Anaconda; Contact: 406-969-6060 mccinfo@mtcancer.org
- Billings: Billings Clinic Cancer Center; Contact 800-996-2663 research@billingsclinic.org
- Bozeman: Bozeman Deaconess Hospital; Contact: 406-969-6060 mccinfo@mtcancer.org
- Great Falls: Benefis Healthcare- Sletten Cancer Institute; Contact: 406-969-6060 mccinfo@mtcancer.org
- Kalispell: Kalispell Regional Medical Center; Contact: 406-969-6060 mccinfo@mtcancer.org
- Missoula: Community Medical Hospital; Contact 406-969-6060 mccinfo@mtcancer.org
- Grand Island: CHI Health Saint Francis; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Kearney: CHI Health Good Samaritan; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Omaha: Nebraska Methodist Hospital; Contact: 402-354-5144
- Omaha: Nebraska Medicine-Village Pointe; Contact: 402-559-5600
- Omaha: Alegent Health Bergan Mercy Medical Center; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Omaha: University of Nebraska Medical Center; Contact: 402-559-6941 unmcrsa@unmc.edu
- Henderson: OptumCare Cancer Care at Seven Hills; Contact: 702-384-0013 research@sncrf.org
- Las Vegas: OptumCare Cancer Care at Oakey/MountainView and Fort Apache; Contact 702-384-0013 research@sncrf.org
- Reno: Renown Regional Medical Center; Contact: 702-384-0013 research@sncrf.org
- Concord: New Hampshire Oncology Hematology PA-Concord; Contact: 603-224-2556
- Exeter: Exeter Hospital; Contact 800-439-3837
- Lebanon: Dartmouth Hitchcock Medical Center; Contact: 800-639-6918 cancer.research.nurse@dartmouth.edu
- Manchester: Solinsky Center for Cancer Care; Contact: 800-339-6484
- Basking Ridge: Memorial Sloan Kettering Basking Ridge; Contact: 212-639-7592
- Egg Harbor Township: AtlantiCare Surgery Center; Contact 609-748-7200
- Hamilton: The Cancer Institute of New Jersey Hamilton; Contact: 609-631-6946
- Middletown: Memorial Sloan Kettering Monmouth; Contact: 212-639-7592
- Montvale: Memorial Sloan Kettering Bergen; Contact: 212-639-7592
- Morristown: Morristown Medic
Study Contact Information:
For additional information, please contact: Principal Investigator: Frank A Sinicrope, Alliance for Clinical Trials in Oncology
Study Contact Information:
For additional information, please contact: Principal Investigator: Frank A Sinicrope, Alliance for Clinical Trials in Oncology