Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair
Clinicaltrials.gov identifier:
NCT02912559
Study Contact Information:
For additional information, please contact: Principal Investigator: Frank A Sinicrope, Alliance for Clinical Trials in Oncology
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair
About the Study
may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
This phase III trial is for people with 3 colon cancer. The study will compare how well treatment with a combination of chemotherapy agents and an immunotherapy agent works compared with treatment with combination chemotherapy agents alone. This study is focused on patients who have a known as or , which are commonly seen in people with . NOTE: This study is no longer enrolling people.
What the Study Entails
People will be assigned randomly to one of two groups:
Group 1: Chemotherapy and immunotherapy
- People in this group will receive combination chemotherapy intravenously (oxaliplatin, leucovorin calcium and fluorouracil) on day 1, then continuously over 46 hours on days 1-3. Treatment repeats every 14 days for up to 12 cycles in the absence of disease progression or unacceptable .
- Patients also receive atezolizumab IV starting on day 1 of cycle 1 or 2. Treatment repeats every 14 days for up to 25 cycles in the absence of disease progression or unacceptable toxicity.
Group 2: Chemotherapy only
- People in this group will receive combination chemotherapy intravenously (oxaliplatin, leucovorin calcium, and fluorouracil) on day 1, then continuously over 46 hours on days 1-3. Treatment repeats every 14 days for up to 12 cycles in the absence of disease progression or unacceptable toxicity.
Both groups of participants will be followed for up to 5 years.
Study Sites
- Anchorage: Katmai Oncology Group; Contact: 907-212-6871 or email
- Tucson: Banner University Medical Center - Tucson; Contact by email
- Tucson: University of Arizona Cancer Center-North Campus; Contact: 800-327-2873
- Anaheim: Kaiser Permanente-Anaheim; Contact: 800-398-3996 or email
- Arroyo Grande: PCR Oncology; Contact: 702-384-0013 or email
- Auburn: Sutter Auburn Faith Hospital; Contact: 415-209-2686 or email
- Baldwin Park: Kaiser Permanente-Baldwin Park;Contact: 800-398-3996 or email
- Bellflower: Kaiser Permanente-Bellflower; Contact: 800-398-3996 or email
- Berkeley: Alta Bates Summit Medical Center-Herrick Campus; Contact: 415-209-2686 or email
- Clovis: University Oncology Associates; Contact: 559-256-9680
- Dublin: Epic Care-Dublin; Contact: 925-875-1677
- Emeryville: Epic Care Partners in Cancer Care; Contact: 510-629-6682
- Fontana: Kaiser Permanente-Fontana; Contact: 800-398-3996 or email
- Fremont: Palo Alto Medical Foundation-Fremont; Contact by email
- Harbor City: Kaiser Permanente - Harbor City; Contact: 800-398-3996 or email
- Irvine: Kaiser Permanente-Irvine; Contact: 800-398-3996 or or email
- Los Angeles:Kaiser Permanente Los Angeles Medical Center; Contact: 800-398-3996 or email
- Los Angeles County-USC Medical Center; Contact: 323-865-0451
- Los Angeles: USC / Norris Comprehensive Cancer Center; Contact: 323-865-0451
- Los Angeles: Kaiser Permanente-Cadillac; Contact: 800-398-3996 or email
- Martinez: Contra Costa Regional Medical Center; Contact: 925-957-5400
- Marysville: Fremont - Rideout Cancer Center; Contact: 530-749-4400
- Modesto: Memorial Medical Center; Contact: 415-209-2686 or email
- Mountain View: Palo Alto Medical Foundation-Camino Division; Contact: 415-209-2686 or email
- Ontario: Kaiser Permanente-Ontario; Contact: 800-398-3996 or email
- Orange: UC Irvine Health/Chao Family Comprehensive Cancer Center; Contact: 877-827-8839 or email
- Palo Alto: Palo Alto Medical Foundation Health Care; Contact: 415-209-2686 or email
- Palo Alto: Stanford Cancer Institute Palo Alto; Contact: 650-498-7061 or email
- Palo Alto: VA Palo Alto Health Care System; Contact: 800-455-0057
- Panorama City: Kaiser Permanente - Panorama City; Contact: 800-398-3996 or email
- Riverside: Kaiser Permanente - Riverside; Contact: 800-398-3996 or email
- Roseville: Sutter Roseville Medical Center; Contact: 415-209-2686 or email
- Sacramento: Sutter Medical Center Sacramento; Contact: 415-209-2686 or email
- Sacramento: University of California Davis Comprehensive Cancer Center; Contact: 916-734-3089
- Salinas: Salinas Valley Memorial; Contact: 831-759-1838 or email
- San Diego: Kaiser Permanente-San Diego Zion; Contact: 800-398-3996 or email
- San Diego: Sharp Memorial Hospital; Contact: 858-939-5062 or email
- San Francisco: California Pacific Medical Center-Pacific Campus; Contact: 415-209-2686 or email
- San Marcos: Kaiser Permanente-San Marcos; Contact: 800-398-3996 or email
- Santa Cruz: Palo Alto Medical Foundation-Santa Cruz; Contact: Site Public Contact: 415-209-2686 or email
- Sunnyvale: Palo Alto Medical Foundation-Sunnyvale; Contact: Site Public Contact: 415-209-2686 or email
- Vellego: Sutter Solano Medical Center/Cancer Center; Contact: Site Public Contact: 415-209-2686 or email
- Woodland Hills: Kaiser Permanente-Woodland Hills; Contact: 800-398-3996 or email
- Aurora: Rocky Mountain Cancer Centers-Aurora; Contact: 303-777-2663 or email
- Aurora: University of Colorado Hospital; Contact:720-848-0650
- Boulder: Boulder Community Hospital; Contact 303-777-2663 or email
- Boulder: Rocky Mountain Cancer Centers-Boulder; Contact 303-777-2663 or email
- Colorado Springs: Penrose-Saint Francis Healthcare; Contact: 308-398-6518 or email
- Colorado Springs: UCHealth Memorial Hospital Central; Contact: 719-365-2406
- Colorado Springs: Memorial Hospital North; Contact: 719-364-6700
- Denver: Kaiser Permanente-Franklin; Contact: 303-764-5056 or email
- Denver: National Jewish Health-Main Campus; Contact: 877-225-5654 or email
- Denver: Rocky Mountain Cancer Centers-Midtown; Contact: 303-777-2663 or email
- Denver: SCL Health Saint Joseph Hospital; Contact: 303-777-2663 or email
- Denver: Rocky Mountain Cancer Centers-Rose; Contact: 303-777-2663 or email
- Englewood: Swedish Medical Center; Contact: 303-777-2663 or email
- Englewood: Mountain Blue Cancer Care Center - Swedish; Contact: 303-777-2663 or email
- Fort Collins: Poudre Valley Hospital; Contact: 970-297-6150
- Fort Collins: Cancer Care and Hematology-Fort Collins; Contact: 888-823-5923 or email
- Golden: National Jewish Health-Western Hematology Oncology; Contact: 303-777-2663 or email
- Grand Junction:Saint Mary's Hospital and Regional Medical Center; Contact: 303-777-2663 or email
- Greeley: North Colorado Medical Center; Contact: 303-777-2663 or email
- Greeley: UCHealth Greeley Hospital;Contact: 888-823-5923 or email
- Lafayette: Good Samaritan Medical Center; Contact: 303-673-1622
- Lafayette: Kaiser Permanente-Rock Creek; Contact: 303-764-5056 or email
- Littleton: Rocky Mountain Cancer Centers-Littleton; Contact: 303-777-2663 or email
- Lone Tree: Kaiser Permanente-Lone Tree; Contact: 303-764-5056 or email
- Lone Tree: Rocky Mountain Cancer Centers-Sky Ridge; Contact: 303-777-2663 or email
- Longmont: Longmont United Hospital; Contact: 308-398-6518 or email
- Loveland: Medical Center of the Rockies; Contact: 970-203-7083
- Loveland: McKee Medical Center; Contact: 303-777-2663 or email
- Thornton: National Jewish Health-Northern Hematology Oncology; Contact: 303-777-2663 or email
- Wheat Ridge: SCL Health Lutheran Medical Center; Contact: 303-777-2663 or email
- Derby: Smilow Cancer Hospital-Derby Care Center; Contact: 203-785-5702 or email
- Fairfield: Smilow Cancer Hospital Care Center-Fairfield; Contact: 203-785-5702 or email
- Guildford: Smilow Cancer Hospital Care Center - Guiford; Contact: 203-785-5702 or email
- Hartford: Smilow Cancer Hospital Care Center at Saint Francis; Contact: 203-785-5702 or email
- Middletown: Middlesex Hospital; Contact: 860-358-2058 or email
- New Haven: Yale University; Contact: 203-785-5702 or email
- North Haven: Yale-New Haven Hospital North Haven Medical Center; Contact: 203-785-5702 or email
- Torrington: Smilow Cancer Hospital-Torrington Care Center ;Contact: 203-785-5702 or email
- Trumbull: Smilow Cancer Hospital Care Center-Trumbull; Contact: 203-785-5702 or email
- Waterbury: Smilow Cancer Hospital-Waterbury Care Center; Contact: 203-785-5702 or email
- Waterford: Smilow Cancer Hospital-Waterford Care Center; Contact: 203-785-5702 or email
- Frankford: Beebe South Coastal Health Campus; Contact: 302-645-3100 or email
- Newark: Helen F Graham Cancer Center; Contact: 302-623-4450 or email
- Newark: Medical Oncology Hematology Consultants PA; Contact: 302-623-4450 or email
- Rehoboth Beach: Beebe Health Campus; Contact: 302-645-3100 or email
- Sibley Memorial Hospital; Contact: 202-243-2373 or email
- Aventura: Mount Sinai Comprehensive Cancer Center at Aventura; Contact: 305-674-2625 or email
- Daytona Beach: Halifax Health Medical Center-Centers for Oncology; Contact: 386-254-4211
- Fort Lauderdale: Broward Health Medical Center; Contact: 954-355-5346
- Fort Myers: Regional Cancer Center-Lee Memorial Health System; Contact: 773-702-9171 or email
- Miami Beach: Mount Sinai Medical Center; Contact:305-674-2625 or email
- Orlando: AdventHealth Orlando; Contact: 407-303-2090 or email
- Albany: Phoebe Putney Memorial Hospital Contact: 229-312-0405 or email
- Athens: University Cancer and Blood Center LLC; Contact: 706-353-5006 or email
- Augusta: Augusta Oncology Associates PC-D'Antignac; Contact: 706-821-2944
- Augusta: Augusta Oncology Associates PC-Wheeler; Contact: 706-736-1830
- 'Aiea: Pali Momi Medical Center; Contact: 808-486-6000
- Honolulu: Queen's Cancer Cenrer - POB I; Contact: 808-532-0315
- Honolulu: Queen's Medical Center; Contact: 808-545-8548
- Honolulu: Straub Clinic and Hospital; Contact: 808-522-4333
- Honolulu: Queen's Cancer Center - Kuakini; Contact: 808-531-8521
- Boise: Saint Alphonsus Cancer Care Center-Boise; Contact: 734-712-3671 or email
- Boise: Saint Luke's Mountain States Tumor Institute; Contact: 208-381-2774 or email
- Caldwell: Saint Alphonsus Cancer Care Center-Caldwell; Contact: 734-712-3671 or email
- Coeur d'Alene: Kootenai Medical Center; Contact: 406-969-6060 or email
- Fruitland: Saint Luke's Cancer Institute - Fruitland; Contact: 208-381-2774 or email
- Meridian: Saint Luke's Cancer Institute - Meridian; Contact: 208-381-2774 or email
- Nampa: Saint Alphonsus Medical Center-Nampa; Contact: 734-712-3671 or email
- Nampa: Saint Luke's Cancer Institute - Nampa; Contact: 208-381-2774 or email
- Post Falls: Kootenai Cancer Center; Contact: 406-969-6060 or email
- Sandpoint: Kootenai Cancer Center; Contact: 406-969-6060 or email
- Twin Falls:Saint Luke's Cancer Institute - Twin Falls; Contact: 208-381-2774 or email
- Bloomington: Illinois CancerCare-Bloomington; Contact: 309-243-3605 or email
- Canton: Illinois CancerCare-Canton; Contact: 309-243-3605 or email
- Carterville: SIH Cancer Institute; Contact: 618-985-3333 or email
- Carthage: Illinois CancerCare-Carthage; Contact: 309-243-3605 or email
- Centralia: Centralia Oncology Clinic; Contact: 217-876-4740 or email
- Chicago: Northwestern University; Contact: 312-695-1301 or email
- Chicago: Rush University Medical Center; Contact : 312-942-5498 or email
- Crystal Lake: AMG Crystal Lake - Oncology; Contact: Site Public Contact 630-929-6129 or email
- Decatur: Cancer Care Specialists of Illinois - Decatur; Contact: 217-876-4740 or email
- Dixon: Illinois CancerCare-Dixon; Contact 815-285-7800
- Eureka: Illinois CancerCare-Eureka; Contact 309-243-3605 or email
- Evanston: NorthShore University HealthSystem-Evanston Hospital; Contact: 847-570-2109
- Freeport: Freeport Memorial Hospital/Leonard C Ferguson Cancer Center; Contact: 815-599-7000
- Galesburg: Illinois CancerCare-Galesburg; Contact: 309-243-3605 andersonj@illinoiscancercare.com
- Geneva: Northwestern Medicine Cancer Center Delnor; Contact: 630-352-5360 Donald.Smith3@nm.org
- Glenview: NorthShore University HealthSystem-Glenbrook Hospital; Contact: 847-570-2109
- Harvey:Ingalls Memorial Hospital; Contact: 708-915-4673 clinicaltrials@ingalls.org
- Highland Park: NorthShore University HealthSystem-Highland Park Hospital: Contact: 847-570-2109
- Kewanee: Illinois CancerCare-Kewanee Clinic; Contact: 309-243-3605 andersonj@illinoiscancercare.com
- Lake Forest: Northwestern Medicine Lake Forest Hospital: Contact: cancertrials@northwestern.edu
- Libertyville: AMG Libertyville - Oncology; Contact: 630-929-6129 advocateresearch@advocatehealth.com
- Macomb: Illinois CancerCare-Macomb; Contact: 309-243-3605 andersonj@illinoiscancercare.com
- Maywood: Loyola University Medical Center; Contact: 708-226-4357
- Mount Vernon: Good Samaritan Regional Health Center; Contact: 618-242-4600
- O'Fallon: Cancer Care Center of O'Fallon; Contact 217-876-4762 morganthaler.jodi@mhsil.com
- Ottawa: Illinois CancerCare-Ottawa Clinic; Contact: 309-243-3605 andersonj@illinoiscancercare.com
- Park Ridge: Advocate Lutheran General Hospital; Contact: 847-384-3621
- Pekin: Illinois CancerCare-Pekin; Contact: 309-243-3605 andersonj@illinoiscancercare.com
- Peoria: Illinois CancerCare-Peoria; Contact: 309-243-3605 andersonj@illinoiscancercare.com
- Peru: Illinois CancerCare-Peru; Contact: 309-243-3605 andersonj@illinoiscancercare.com
- Princeton: Illinois CancerCare-Princeton; Contact: 309-243-3605 andersonj@illinoiscancercare.com
- Silvis: Genesis Cancer Center - Silvis; Contact: 563-421-1908 turnerk@genesishealth.com
- Springfield: Southern Illinois University School of Medicine; Contact: 217-545-7929
- Springfield: Springfield Clinic; Contact: 800-444-7541
- Warrenville: Northwestern Medicine Cancer Center Warrenville; Contact: 630-352-5360 Donald.Smith3@nm.org
- Indianapolis: Indiana University/Melvin and Bren Simon Cancer Center; Contact: 317-278-5632 iutrials@iu.edu
- Indianapolis: Sidney and Lois Eskenazi Hospital Contact 317-278-5632 iutrials@iu.edu
- Indianapolis: Franciscan Health Indianapolis; Contact: 317-528-7060
- Mooresville: Franciscan Health Mooresville; Contact: 317-834-3603
- Richmond: Reid Health; Contact: 937-528-2900 clinical.trials@daytonncorp.org
- Terre Haute: Union Hospital; Contact: 812-238-7394
- Ames: Mary Greeley Medical Center; Contact: 515-956-4132
- Ames: McFarland Clinic PC - Ames; Contact: 515-239-4734 ksoder@mcfarlandclinic.com
- Bettendorf: University of Iowa Healthcare Cancer Services Quad Cities; Contact: 563-355-7733 kedaprile@rccqc.com
- Boone: McFarland Clinic PC-Boone; Contact: 515-956-4132
- Cedar Rapids: Mercy Hospital; Contact: 319-365-4673
- Cedar Rapids: Oncology Associates at Mercy Medical Center; Contact 319-363-2690
- Clive: Medical Oncology and Hematology Associates-West Des Moines; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Clive: Mercy Cancer Center-West Lakes; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Davenport: Genesis Medical Center - East Campus; Contact: 563-421-1908 turnerk@genesishealth.com
- Davenport: Iowa Cancer Specialists; Contact: 563-421-1908 turnerk@genesishealth.com
- Des Moines: Iowa Methodist Medical Center; Contact: 515-241-6727
- Des Moines: Medical Oncology and Hematology Associates-Des Moines; Contact: 515-282-2921
- Des Moines: Broadlawns Medical Center; Contact: 515-282-2200
- Des Moines: Medical Oncology and Hematology Associates-Laurel; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Des Moines: Mercy Medical Center - Des Moines; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Fort Dodge: McFarland Clinic PC-Trinity Cancer Center; Contact : 515-956-4132
- Iowa City: University of Iowa/Holden Comprehensive Cancer Center; Contact: 800-237-1225
- Jefferson: McFarland Clinic PC-Jefferson; Contact: 515-956-4132
- Marshalltown: McFarland Clinic PC-Marshalltown; Contact: 515-956-4132
- Sioux City: Siouxland Regional Cancer Center; Contact: 712-252-9326 HoopingarnerT@jencc.com
- West Des Moines: Mercy Medical Center-West Lakes; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Hays: HaysMed University of Kansas Health System
- Kansas City:University of Kansas Cancer Center-West; Contact: 913-588-3671 or email
- Liberal: Cancer Center of Kansas-Liberal; Contact: 316-268-5374 or email
- Olathe: Olathe Health Cancer Center; Contact: 913-355-8000 Jeni.wakefield@olathehealth.org
- Overland Park: University of Kansas Cancer Center-Overland Park; Contact: 913-588-3671 KUCC_Navigation@kumc.edu
- Pittsburg: Ascension Via Christi - Pittsburg; Contact: 620-235-7900 jennifer.jameson@ascension.org
- Salina: Salina Regional Health Center; Contact: 785-452-7038 mleepers@srhc.com
- Topeka: University of Kansas Health System Saint Francis Campus; Contact: 785-295-8000
- Westwood: University of Kansas Hospital-Westwood Cancer Center; Contact: 913-588-3671 KUCC_Navigation@kumc.edu
- Wichita: Cancer Center of Kansas-Wichita Medical Arts Tower; Contact: 316-268-5374 Keisha.humphries@ascension.org
- Edgewood: Saint Elizabeth Medical Center South; Contact: 859-301-5473 darla.hehman@stelizabeth.com
- Fort Thomas: Saint Elizabeth Fort Thomas; Contact 859-301-9418
- Lexington: Baptist Health Lexington; Contact: 859-260-6425
- Lexington: Saint Joseph Hospital East; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Lexington: University of Kentucky/Markey Cancer Center; Contact: 859-257-3379
- Baton Rouge: LSU Health Baton Rouge-North Clinic; Contact: 225-215-1353 clinicalresearch@marybird.com
- Baton Rouge: Louisiana Hematology Oncology Associates LLC; Contact: 225-215-1353 clinicalresearch@marybird.com
- Baton Rouge: Mary Bird Perkins Cancer Center; Contact: 225-215-1353 clinicalresearch@marybird.com
- Baton Rouge: Our Lady of the Lake - Medical Oncology; Contact: 225-215-1353 clinicalresearch@marybird.com
- Kenner: Ochsner Medical Center Kenner; Contact: 504-464-8314 cris.molina@ochsner.org
- New Orleans: Ochsner Medical Center Jefferson; Contact: 504-703-8712 Gregory.Johnstone@ochsner.org
- Augusta: Harold Alfond Center for Cancer Care; Contact: 207-626-4855
- Belfast: Waldo County General Hospital; Contact: 207-338-2500
- Biddeford: MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford; Contact LLemire@mmc.org
- Brewer: Lafayette Family Cancer Center-EMMC; Contact: 800-987-3005
- Rockport: Penobscot Bay Medical Center; Contact: 207-396-8670 ClinicalResearch@mmc.org
- Sanford: MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford; Contact LLemire@mmc.org
- South Portland: Maine Medical Partners - South Portland; Contact: 207-396-8670 ClinicalResearch@mmc.org
- Baltimore: Saint Agnes Hospital; Contact: 410-368-2910
- Baltimore: Johns Hopkins University/Sidney Kimmel Cancer Center; Contact: 410-955-8804 jhcccro@jhmi.edu
- Glen Burnie: UM Baltimore Washington Medical Center/Tate Cancer Center; Contact: 410-553-8100
- Boston: Boston Medical Center; Contact: 617-638-8265
- Boston: Beth Israel Deaconess Medical Center; Contact: 617-667-9925
- Boston: Dana-Farber Cancer Institute; Contact: 877-442-3324
- Ann Arbor: Saint Joseph Mercy Hospital; Contact: 734-712-3671 stephanie.couch@stjoeshealth.org
- Battle Creek: Bronson Battle Creek; Contact: 616-391-1230 crcwm-regulatory@crcwm.org
- Bay City: McLaren Cancer Institute-Bay City; Contact: 313-576-9790 ctoadmin@karmanos.org
- Bloomfield: McLaren Cancer Institute-Bloomfield; Contact: 313-576-9790 ctoadmin@karmanos.org
- Brighton: IHA Hematology Oncology Consultants-Brighton; Contact: 734-712-3671 stephanie.couch@stjoeshealth.org
- Brighton: Saint Joseph Mercy Brighton; Contact: 734-712-3671 stephanie.couch@stjoeshealth.org
- Brownstown: Henry Ford Cancer Institute-Downriver; Contact: 313-916-3721 CTOResearch@hfhs.org
- Canton: IHA Hematology Oncology Consultants-Canton; Contact: 734-712-3671 stephanie.couch@stjoeshealth.org
- Canton: Saint Joseph Mercy Canton; Contact: 734-712-3671 stephanie.couch@stjoeshealth.org
- Chelsea: IHA Hematology Oncology Consultants-Chelsea; Contact: 734-712-3671 or email
- Chelsea: Saint Joseph Mercy Chelsea; Contact: 734-712-3671 or email
- Clarkston: Hematology Oncology Consultants-Clarkston; Contact: 734-712-3671 or email
- Clarkston: McLaren Cancer Institute-Clarkston; Contact: 313-576-9790 or email
- Dearborn: Beaumont Hospital-Dearborn; Contact: 248-551-7695
- Dearborn: Henry Ford Medical Center-Fairlane; Contact: 313-916-3721 or email
- Detroit:Wayne State University/Karmanos Cancer Institute; Contact: 313-576-9790 or email
- Detroit: Henry Ford Hospital; Contact: 313-916-3721 or email
- East China Township: Great Lakes Cancer Management Specialiists - Doctors Park; Contact: 734-712-3671 or email
- Farmington Hills: Weisberg Cancer Treatment Center; Contact: 313-576-9790 or email
- Flint: McLaren Cancer Institute-Flint; ; Contact: 313-576-9790 or by email
- Flint: Genessee Cancer and Blood Disease Center: Contact: 734-712-3671 or email
- Flint: Singh and Arora Hematology Oncology PC; Contact: 313-576-9790 or email
- Grand Rapids: Spectrum Health at Butterworth Campus; Contact: 616-391-1230 or email
- Grosse Point Woods: Academic Hematology Oncology Specialists; Contact: 734-712-3671 or email
- Grosse Point Woods: Great Lakes Cancer Management Specialists-Van Elslander Cancer Center; Contact: 734-712-3671 or email
- Jackson: Allegiance Health; Contact: 313-916-3721 or by email
- Kalamazoo: West Michigan Cancer Center; Contact: 616-391-1230 or email
- Lansing: McLaren-Greater Lansing; Contact: 313-576-9790 or email
- Lansing: Sparrow Hospital; Contact: 734-712-3671 or email
- Lapeer: McLaren Cancer Institute-Lapeer Region; Contact: 313-576-9790 or email
- Livonia: Hope Cancer Clinic; Contact: 734-712-3671 or email
- Livonia: Saint Mary Mercy Hospital; Contact: 734-712-3671 or email
- Mount Clemens: McLaren Cancer Institute-Macomb; Contact: 313-576-9790 or email
- Mount Pleasant: McLaren Cancer Institute-Central Michigan; Contact: 313-576-9790 or email
- Novi: Henry Ford Medical Center-Columbus; Contact: 313-916-3721 or by email
- Petoskey: McLaren Cancer Institute-Northern Michigan; Contact: 313-576-9790 or email
- Pontiac: Saint Joseph Mercy Oakland; Contact: 734-712-3671 or email
- Port Huron: McLaren-Port Huron; Contact: 313-576-9790 or email
- Royal Oak: William Beaumont Hospital-Royal Oak; Contact: 248-551-7695
- Saginaw: Ascension Saint Mary's Hospital; Contact: 734-712-3671 or email
- Southfield: Ascension Providence Hospitals - Southfield; Contact: 248-849-5332 or email
- Tawas City: Ascension Saint Joseph Hospital; Contact: 734-712-3671 or email
- Traverse City: Munson Medical Center; Contact: 616-391-1230 or email
- Troy: William Beaumont Hospital-Troy; Contact: 248-551-7695
- Warren: Great Lakes Cancer Management Specialists-Macomb Professional Building; Contact: 734-712-3671 or email
- West Bloomfield: Henry Ford West Bloomfield Hospital; Contact: 313-916-3721 or by email
- West Branch: Saint Mary's Oncology/Hematology Associates of West Branch; Contact: 734-712-3671 or email
- Ypsilanti: IHA Hematology Oncology Consultants-Ann Arbor; Contact: 734-712-3671 or email
- Albert Lea: Mayo Clinic Health System in Albert Lea; Contact: 855-776-0015
- Bemidji: Sanford Joe Lueken Cancer Center; Contact: 218-333-5000 OncologyClinicalTrialsFargo@sanfordhealth.org
- Burnsville: Fairview Ridges Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Coon Rapids: Mercy Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Deer River: Essentia Health - Deer River Clinic; Contact: 218-786-3308 CancerTrials@EssentiaHealth.org
- Duluth: Essentia Health Cancer Center; Contact: 218-786-3308 CancerTrials@EssentiaHealth.org
- Edina: Fairview Southdale Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Fridley: Unity Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Hibbing: Essentia Health Hibbing Clinic; Contact: 218-786-3308
- Mankato: Mayo Clinic Health Systems-Mankato; Contact: 855-776-0015
- Maplewood: Minnesota Oncology Hematology PA-Maplewood; Contact: 952-993-1517 mmcorc@healthpartners.com
- Maplewood: Saint John's Hospital - Healtheast; Contact: 952-993-1517 mmcorc@healthpartners.com
- Minneapolis: Abbott-Northwestern Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Minneapolis: Hennepin County Medical Center; Contact: 952-993-1517 mmcorc@healthpartners.com
- Minneapolis: Health Partners; Contact: 952-993-1517 mmcorc@healthpartners.com
- Rochester: Mayo Clinic in Rochester; Contact: 855-776-0015
- Saint Cloud: Coborn Cancer Center at Saint Cloud Hospital; Contact: 877-229-4907 coborncancercenter@centracare.com
- Saint Louis Park: Park Nicollet Clinic - Saint Louis Park; Contact: 952-993-1517 mmcorc@healthpartners.com
- Saint Paul: Regions Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Saint Paul: United Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Sandstone: Essentia Health Sandstone; Contact 218-786-3308 CancerTrials@EssentiaHealth.org
- Stillwater: Lakeview Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Virginia: Essentia Health Virginia Clinic; Contact: 218-786-3308 CancerTrials@EssentiaHealth.org
- Waconia: Ridgeview Medical Center; Waconia, Minnesota, 55387
- Wilmar: Rice Memorial Hospital; Contact: 952-993-1517 mmcorc@healthpartners.com
- Woodbury: Minnesota Oncology Hematology PA-Woodbury; Contact: 952-993-1517 mmcorc@healthpartners.com
- Ballwin: Saint Louis Cancer and Breast Institute-Ballwin; Contact: 314-251-7058
- Cape Girardeau: Saint Francis Medical Center; Contact: 573-334-2230 sfmc@sfmc.net
- Cape Girardeau: Southeast Cancer Center; Contact: 573-651-5550
- Columbia: University of Missouri - Ellis Fischel; Contact: 573-882-7440
- Creve Coeur: Siteman Cancer Center at West County Hospital; Contact: 800-600-3606 info@siteman.wustl.edu
- Joplin: Mercy Hospital Joplin; Contact: 417-556-3074 esmeralda.carrillo@mercy.net
- Kansas City: Truman Medical Centers; Contact: 816-404-4375
- Kansas City: University of Kansas Cancer Center - North; Contact: 913-588-3671 KUCC_Navigation@kumc.edu
- Lee's Summit: University of Kansas Cancer Center - Lee's Summit; Contact: 913-588-3671 KUCC_Navigation@kumc.edu
- Saint Louis: Washington University School of Medicine; Contact: 800-600-3606 info@siteman.wustl.edu
- Saint Louis: Siteman Cancer Center-South County; Contact: 800-600-3606 info@siteman.wustl.edu
- Saint Louis: Missouri Baptist Medical Center; Contact: 314-996-5569
- Saint Louis: Siteman Cancer Center at Christian Hospital; Contact: 800-600-3606 info@siteman.wustl.edu
- Saint Peters: Siteman Cancer Center at Saint Peters Hospital; Contact: 800-600-3606 info@siteman.wustl.edu
- Sainte Genevieve: Sainte Genevieve County Memorial Hospital; Contact: 314-996-5569
- Springfield: Mercy Hospital Springfield; Contact: 417-269-4520
- Sullivan: Missouri Baptist Sullivan Hospital; Contact: 314-996-5569
- Sunset Hills: Missouri Baptist Outpatient Center-Sunset Hills; Contact: 314-996-5569
- Anaconda: Community Hospital of Anaconda; Contact: 406-969-6060 mccinfo@mtcancer.org
- Billings: Billings Clinic Cancer Center; Contact 800-996-2663 research@billingsclinic.org
- Bozeman: Bozeman Deaconess Hospital; Contact: 406-969-6060 mccinfo@mtcancer.org
- Great Falls: Benefis Healthcare- Sletten Cancer Institute; Contact: 406-969-6060 mccinfo@mtcancer.org
- Kalispell: Kalispell Regional Medical Center; Contact: 406-969-6060 mccinfo@mtcancer.org
- Missoula: Community Medical Hospital; Contact 406-969-6060 mccinfo@mtcancer.org
- Grand Island: CHI Health Saint Francis; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Kearney: CHI Health Good Samaritan; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Omaha: Nebraska Methodist Hospital; Contact: 402-354-5144
- Omaha: Nebraska Medicine-Village Pointe; Contact: 402-559-5600
- Omaha: Alegent Health Bergan Mercy Medical Center; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Omaha: University of Nebraska Medical Center; Contact: 402-559-6941 unmcrsa@unmc.edu
- Henderson: OptumCare Cancer Care at Seven Hills; Contact: 702-384-0013 research@sncrf.org
- Las Vegas: OptumCare Cancer Care at Oakey/MountainView and Fort Apache; Contact 702-384-0013 research@sncrf.org
- Reno: Renown Regional Medical Center; Contact: 702-384-0013 research@sncrf.org
- Concord: New Hampshire Oncology Hematology PA-Concord; Contact: 603-224-2556
- Exeter: Exeter Hospital; Contact 800-439-3837
- Lebanon: Dartmouth Hitchcock Medical Center; Contact: 800-639-6918 cancer.research.nurse@dartmouth.edu
- Manchester: Solinsky Center for Cancer Care; Contact: 800-339-6484
- Basking Ridge: Memorial Sloan Kettering Basking Ridge; Contact: 212-639-7592
- Egg Harbor Township: AtlantiCare Surgery Center; Contact 609-748-7200
- Hamilton: The Cancer Institute of New Jersey Hamilton; Contact: 609-631-6946
- Middletown: Memorial Sloan Kettering Monmouth; Contact: 212-639-7592
- Montvale: Memorial Sloan Kettering Bergen; Contact: 212-639-7592
- Morristown: Morristown Medical Center; Contact: 973-971-5900
- Mulica Hill: Inspira Medical Center Mullica Hill; Contact: 856-508-3500 DeNigrisJ@ihn.org
- New Brunswick: Rutgers Cancer Institute of New Jersey; Contact: 732-235-7356
- Newark: Newark Beth Israel Medical Center; Contact: 973-926-7230 Christine.Kosmides@rwjbh.org
- Paramus: The Valley Hospital-Luckow Pavilion; Contact: 201-634-5792
- Somerville:Robert Wood Johnson University Hospital Somerset; Contact: 908-685-2481 Siby.Varughese@rwjbh.org
- Albuquerque: University of New Mexico Cancer Center; Contact: 505-925-0366 LByatt@nmcca.org
- Albuquerque: Presbyterian Kaseman Hospital; Contact: 505-559-6113 WBurman@phs.org
- Rio Rancho: Presbyterian Rust Medical Center/Jorgensen Cancer Center; Contact: 505-559-6113 WBurman@phs.org
- Auburn: Hematology Oncology Associates of Central New York-Auburn; Contact: 315-472-7504
- Brooklyn: Maimonides Medical Center; Contact: 718-765-2500
- Buffalo: Roswell Park Cancer Institute; Contact: 800-767-9355 askroswell@roswellpark.org
- Commack: Memorial Sloan Kettering Commack; Contact: 212-639-7592
- Cooperstown: Mary Imogene Bassett Hospital; Contact 877-547-1750 CancerClinicalTrials@bassett.org
- East Hills: Cancer Institute at Saint Francis Hospital; Contact: 773-702-9171 protocols@AllianceNCTN.org
- East Syracuse: Hematology Oncology Associates of Central New York-East Syracuse; Contact: 315-472-7504
- Elmira: Arnot Ogden Medical Center/Falck Cancer Center; Contact: 607-271-7000
- Harrison: Memorial Sloan Kettering Westchester; Contact: 212-639-7592
- New York: Mount Sinai West; Contact: 212-824-7309 CCTO@mssm.edu
- New York: NYP/Columbia University Medical Center; Contact: 212-305-6361 nr2616@cumc.columbia.edu
- New York: Memorial Sloan Kettering Cancer Center: Contact 212-639-7592
- New York: NYP/Weill Cornell Medical Center; Contact: 212-746-1848
- Stony Brook: Stony Brook University Medical Center; Contact: 800-862-2215
- Syracuse: State University of New York Upstate Medical University; Contact 315-464-5476
- Syracuse: Hematology Oncology Associates of Central New York-Onondaga Hill; Contact 315-472-7504
- Uniondale: Memorial Sloan Kettering Nassau; Contact: 212-639-7592
- White Plains: Dickstein Cancer Treatment Center; Contact: 914-849-7582 mcortese@wphospital.org
- Albemarle: Atrium Health Stanly/LCI-Albemarle; Contact: 800-804-9376
- Asheboro: Randolph Hospital; Contact: 336-832-0836 vivian.sheidler@conehealth.com
- Asheville: AdventHealth Infusion Center Asheville; Contact: 828-650-8037 AMBER.WHEELER@AdventHealth.com
- Burlington: Cone Health Cancer Center at Alamance Regional; Contact: 336-538-7725 kaye.shoffner@conehealth.com
- Charlotte: Carolinas Medical Center/Levine Cancer Institute; Contact: 800-804-9376
- Charlotte: Atrium Health Pineville/LCI-Pineville; Contact: 980-442-2000
- Charlotte: Levine Cancer Institute-SouthPark; Contact: 980-442-2000
- Charlotte: Levine Cancer Institute-Ballantyne; Contact: 800-804-9376
- Clinton: Southeastern Medical Oncology Center-Clinton; Contact: 919-587-9084 jfields@cancersmoc.com
- Clyde: AdventHealth Infusion Center Haywood; Contact: 828-650-8037 AMBER.WHEELER@AdventHealth.com
- Concord: Atrium Health Cabarrus/LCI-Concord; Contact: 800-804-9376
- Durham: Duke University Medical Center; Contact 888-275-3853
- Gastonia: Levine Cancer Institute-Gaston; Contact: 800-804-9376
- Goldsboro: Southeastern Medical Oncology Center-Goldsboro; Contact: 919-587-9084 jfields@cancersmoc.com
- Greensboro: Cone Health Cancer Center; Contact: 336-832-0821 vivian.sheidler@conehealth.com
- Greenville: East Carolina University; Contact 252-744-1015 eubankss@ecu.edu
- Hendersonville: Margaret R Pardee Memorial Hospital; Contact: 828-696-4716 karen.morris@unchealth.unc.edu
- Hendersonville: AdventHealth Hendersonville; Contact: 828-650-8037 AMBER.WHEELER@AdventHealth.com
- Jacksonville: Southeastern Medical Oncology Center-Jacksonville; Contact 910-587-9084 jfields@cancersmoc.com
- Kenansville: Vidant Oncology-Kenansville; Contact: 252-559-2201 Carla.Zimmerman@vidanthealth.com
- Kinston: Vidant Oncology-Kinston; Contact 252-559-2201 Carla.Zimmerman@vidanthealth.com
- Lincolnton: Atrium Health Lincoln/LCI-Lincolnton; Contact: 800-804-9376
- Monroe: Atrium Health Union/LCI-Union; Contact: 980-442-2000
- Shelby: Atrium Health Cleveland/LCI-Cleveland; Contact: 800-804-9376
- Washington: Marion L Shepard Cancer Center at Vidant Beaufort Hospital
- Bismark: Sanford Bismarck Medical Center; Contact: 701-323-5760 OncologyClinicalTrialsFargo@sanfordhealth.org
- Fargo: Sanford Broadway Medical Center; Contact: 701-323-5760
- Fargo: Sanford Roger Maris Cancer Center; Contact 701-234-6161
- Minot: Trinity Cancer Care Center; Contact: 800-862-0005
- Beavercreek: Indu and Raj Soin Medical Center; Contact: 937-528-2900 clinical.trials@daytonncorp.org
- Belpre: Strecker Cancer Center-Belpre; Contact: 800-523-3977 sheree@columbusccop.org
- Canton: Mercy Medical Center; Contact: 888-293-4673
- Canton: Aultman Health Foundation; Contact: 330-363-7274
- Centerville: Miami Valley Hospital South; Contact: 937-528-2900 clinical.trials@daytonncorp.org
- Cincinnati: Good Samaritan Hospital – Cincinnati; Contact: 308-398-6518 clinicaltrials@sfmc-gi.org
- Cleveland: Cleveland Clinic Cancer Center/Fairview Hospital; Contact 866-223-8100 TaussigResearch@ccf.org
- Columbus: Ohio State University Comprehensive Cancer Center; Contact: 800-293-5066 Jamesline@osumc.edu
- Columbus: Columbus Oncology and Hematology Associates; Contact: 614-488-2118 sheree@columbusccop.org
- Columbus: Grant Medical Center; Contact 614-566-4475 sheree@columbusccop.org
- Columbus: The Mark H Zangmeister Center ; Contact: 614-488-2118 sheree@columbusccop.org
- Columbus: Doctors Hospital; Contact: 614-566-3275 sheree@columbusccop.org
- Dayton: Dayton Physician-Miami Valley Hospital North; Contact: 937-528-2900 clinical.trials@daytonncorp.org
- Delaware: Delaware Health Center-Grady Cancer Center; Contact: 740-615-0227 sheree@columbusccop.org
- Mansfield: OhioHealth Mansfield Hospital; Contact 419-526-8018 sheree@columbusccop.org
- Mansfield: Cleveland Clinic Cancer Center Mansfield; Contact: 866-223-8100 TaussigResearch@ccf.org
- Marietta: Marietta Memorial Hospital; Contact 800-523-3977 sheree@columbusccop.org
- Marion: OhioHealth Marion General Hospital; Contact: 614-488-2118 sheree@columbusccop.org
- Mayfield Heights: Hillcrest Hospital Cancer Center; Contact 866-223-8100 TaussigResearch@ccf.org
- Newark: Licking Memorial Hospital; Contact: 740-348-4000 sheree@columbusccop.org
- Portsmouth: Southern Ohio Medical Center; Contact: 614-488-2118 sheree@columbusccop.org
- Sandusky: North Coast Cancer Care; Contact: 866-223-8100 TaussigResearch@ccf.org
- Strongsville: Cleveland Clinic Cancer Center Strongsville; Contact: 866-223-8100 TaussigResearch@ccf.org
- Syvania: ProMedica Flower Hospital; Contact: 419-824-1842
- Toledo: Toledo Clinic Cancer Centers-Toledo; Contact: 800-444-3561
- Warrensville Heights: South Pointe Hospital; Contact: 866-223-8100 TaussigResearch@ccf.org
- Wooster: Cleveland Clinic Wooster Family Health and Surgery Center; Contact: 866-223-8100 TaussigResearch@ccf.org
- Youngstown: Saint Elizabeth Youngstown Hospital; Contact: 937-528-2900 clinical.trials@daytonncorp.org
- Zanesville: Genesis Healthcare System Cancer Care Center; Contact: 740-454-5232 sheree@columbusccop.org
- Lawton: Cancer Centers of Southwest Oklahoma Research; Contact: 877-231-4440
- Oklahoma City: University of Oklahoma Health Sciences Center; Contact: 405-271-8777 ou-clinical-trials@ouhsc.edu
- Oklahoma City: Mercy Hospital Oklahoma City; Contact: 405-752-3402
- Tulsa: Oklahoma Cancer Specialists and Research Institute-Tulsa; Contact: 918-505-3200
- Clackamas: Providence Cancer Institute Clackamas Clinic; Contact: 503-215-2614 CanRsrchStudies@providence.org
- Newberg: Providence Newberg Medical Center; Contact: 503-215-2614 CanRsrchStudies@providence.org
- Ontario: Saint Alphonsus Medical Center-Ontario; Contact: 734-712-3671 stephanie.couch@stjoeshealth.org
- Portland: Providence Portland Medical Center; Contact: 503-215-2614 CanRsrchStudies@providence.org
- Portland: Providence Saint Vincent Medical Center; Contact: 503-215-2614 CanRsrchStudies@providence.org
- Allentown: Lehigh Valley Hospital-Cedar Crest; Contact: 734-712-3671 stephanie.couch@stjoeshealth.org
- BethlehemSaint Luke's University Hospital-Bethlehem; Contact: 484-503-4151
- Bethlehem: Lehigh Valley Hospital - Muhlenberg; Contact:734-712-3671 stephanie.couch@stjoeshealth.org
- Bryn Mawr: Bryn Mawr Hospital; Contact: 484-476-2649 turzoe@mlhs.org
- Chambersburg: Chambersburg Hospital: Contact 773-702-9171 protocols@AllianceNCTN.org
- Danville: Geisinger Medical Center; Contact: 570-271-5251 HemonCCTrials@geisinger.edu
- Ephrata: Ephrata Cancer Center; Contact: 717-721-4840
- Gettysburg: Adams Cancer Center; Contact: 877-441-7957
- Harrisburg: UPMC Pinnacle Cancer Center/Community Osteopathic Campus; Contact: 717-724-6765 klitchfield@PINNACLEHEALTH.org
- Hazleton: Geisinger Medical Center-Cancer Center Hazleton; Contact : 570-459-2901 HemonCCTrials@geisinger.edu
- Jefferson Hills:Jefferson Hospital; Contact: 412-359-3043 ddefazio@wpahs.org
- Lebanon: Sechler Family Cancer Center; Contact: 717-741-8303 doxenberg@wellspan.org
- Lewisburg: Geisinger Medical Oncology-Lewisburg; Contact: 570-374-8555 HemonCCTrials@geisinger.edu
- Media: Riddle Memorial Hospital; Contact: 484-476-2649 turzoe@mlhs.org
- Monroeville: Forbes Hospital; Contact: 412-858-7746
- Natrona Heights: Allegheny Valley Hospital; Contact: 724-226-7380
- Paoli: Paoli Memorial Hospital: Contact 484-476-2649 turzoe@mlhs.org
- Philadelphia: Temple University Hospital; Contact : 215-728-2983
- Pittsburgh: Allegheny General Hospital; Contact : 877-284-2000
- Pittsburgh: West Penn Hospital; Contact: 412-578-5000
- Pittsburgh: University of Pittsburgh Cancer Institute (UPCI); Contact: 412-647-8073
- Pottsville: Geisinger Cancer Services-Pottsville; Contact: 800-275-6401 HemonCCTrials@geisinger.edu
- Sayre: Guthrie Medical Group PC-Robert Packer Hospital; Contact: 800-836-0388
- Scranton: Community Medical Center; Contact : 570-703-4768 HemonCCTrials@geisinger.edu
- West Reading: Reading Hospital; Contact: 610-988-9323
- Wilkes-Barre: Geisinger Wyoming Valley/Henry Cancer Center; Contact: 570-271-5251 HemonCCTrials@geisinger.edu
- Willow Grove: Abington Memorial Hospital-Asplundh Cancer Pavilion; Contact: 215-481-2402
- Wynnewood: Lankenau Medical Center; Contact: 484-476-2649 turzoe@mlhs.org
- York: WellSpan Health-York Cancer Center; Contact 877-441-7957
- Providence: Rhode Island Hospital; Contact: 401-444-1488
- Anderson: AnMed Health Cancer Center; Contact: 864-512-4651 rhonda.ballew@anmedhealth.org
- Boiling Springs: Prisma Health Cancer Institute - Spartanburg; Contact : 864-522-2066 kim.williams3@prismahealth.org
- Easley: Prisma Health Cancer Institute - Easley; Contact: 864-522-2066 kim.williams3@prismahealth.org
- Greenville: Saint Francis Hospital; Contact: 864-603-6213 melissa_beckman@bshsi.org
- Greenville: Prisma Health Cancer Institute - Butternut; Contact : 864-522-2066 kim.williams3@prismahealth.org
- Greenville: Prisma Health Cancer Institute - Faris; Contact 864-522-2066 kim.williams3@prismahealth.org
- Greer: Prisma Health Cancer Institute - Greer; Contact: 864-522-2066 kim.williams3@prismahealth.org
- Rock Hill: Levine Cancer Institute-Rock Hill; Contact: 800-804-9376
- Seneca: Prisma Health Cancer Institute - Seneca; Contact : 864-522-2066 kim.williams3@prismahealth.org
- Spartanburg: Spartanburg Medical Center
- Rapid City: Rapid City Regional Hospital; Contact: 605-716-3982 research@rcrh.org
- Sioux Falls: Sanford Cancer Center Oncology Clinic; Contact: 605-312-3320 OncologyClinicTrialsSF@sanfordhealth.org
- Sioux Falls: Avera Cancer Institute; Contact: 605-322-3095 OncRegulatory@avera.org
- Sioux Falls: Sanford USD Medical Center - Sioux Falls; Contact: 605-312-3320 OncologyClinicalTrialsSF@SanfordHealth.org
- Kingsport: Regional Cancer Center at Indian Path Community Hospital; Contact: 423-578-8538 Justin.reynolds@balladhealth.org
- Knoxville: Thompson Cancer Survival Center; Contact: 865-331-1812
- Lenoir City: Thompson Oncology Group-Lenoir City; Contact: 865-331-1812
- Oak Ridge: Thompson Oncology Group-Oak Ridge; Contact: 865-331-1812
The Don and Sybil Harrington Cancer Center
Amarillo, Texas, 79106
Contact: Site Public Contact 806-212-1985 gcravey@harringtoncc.org
Principal Investigator: Anita Ravipati
Dell Seton Medical Center at The University of Texas
Austin, Texas, 78701
Contact: Site Public Contact 512-324-7991
Principal Investigator: Om N. Pandey
MD Anderson in The Woodlands
Conroe, Texas, 77384
Contact: Site Public Contact 866-632-6789 askmdanderson@mdanderson.org
Principal Investigator: George J. Chang
Parkland Memorial Hospital
Dallas, Texas, 75235
Contact: Site Public Contact 214-590-5582 canceranswerline@UTSouthwestern.edu
Principal Investigator: Syed M. Kazmi
UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas, 75390
Contact: Site Public Contact 214-648-7097 canceranswerline@UTSouthwestern.edu
Principal Investigator: Syed M. Kazmi
M D Anderson Cancer Center
Houston, Texas, 77030
Contact: Site Public Contact 877-632-6789 askmdanderson@mdanderson.org
Principal Investigator: George J. Chang
MD Anderson West Houston
Houston, Texas, 77079
Contact: Site Public Contact 877-632-6789 askmdanderson@mdanderson.org
Principal Investigator: George J. Chang
MD Anderson League City
League City, Texas, 77573
Contact: Site Public Contact 877-632-6789 askmdanderson@mdanderson.org
Principal Investigator: George J. Chang
Scott and White Healthcare Round Rock Active, not recruiting
Round Rock, Texas, 78665
MD Anderson in Sugar Land
Sugar Land, Texas, 77478
Contact: Site Public Contact 877-632-6789 askmdanderson@mdanderson.org
Principal Investigator: George J. Chang
Scott and White Memorial Hospital Active, not recruiting
Temple, Texas, 76508
American Fork Hospital / Huntsman Intermountain Cancer Center
American Fork, Utah, 84003
Contact: Site Public Contact 801-855-4100 officeofresearch@imail.org
Principal Investigator: Ramya Thota
Sandra L Maxwell Cancer Center
Cedar City, Utah, 84720
Contact: Site Public Contact 435-868-5680 officeofresearch@imail.org
Principal Investigator: Ramya Thota
Farmington Health Center
Farmington, Utah, 84025
Contact: Site Public Contact 888-424-2100 cancerinfo@hci.utah.edu
Principal Investigator: Glynn W. Gilcrease
Logan Regional Hospital
Logan, Utah, 84321
Contact: Site Public Contact 435-716-6400 officeofresearch@imail.org
Principal Investigator: Ramya Thota
Utah Valley Regional Medical Center
Provo, Utah, 84604
Contact: Site Public Contact 801-357-7965 officeofresearch@imail.org
Principal Investigator: Ramya Thota
Dixie Medical Center Regional Cancer Center
Saint George, Utah, 84770
Contact: Site Public Contact 435-688-4167 officeofresearch@imail.org
Principal Investigator: Ramya Thota
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, 84112
Contact: Site Public Contact 888-424-2100 cancerinfo@hci.utah.edu
Principal Investigator: Glynn W. Gilcrease
Wellmont Medical Associates-Bristol
Bristol, Virginia, 24201
Contact: Site Public Contact 423-578-8538 justin.reynolds@wellmont.org
Principal Investigator: Asheesh Shipstone
University of Virginia Cancer Center
Charlottesville, Virginia, 22908
Contact: Site Public Contact 434-243-6303 PAS9E@virginia.edu
Principal Investigator: Tri M. Le
Centra Lynchburg Hematology-Oncology Clinic Inc
Lynchburg, Virginia, 24501
Contact: Site Public Contact 434-200-5925 Kevin.Patel@centrahealth.com
Principal Investigator: Khalid Matin
Sovah Health Martinsville
Martinsville, Virginia, 24115
Contact: Site Public Contact 276-666-7489 sharon.hubbard@lpnt.net
Principal Investigator: Mohammed Saad
Bon Secours Memorial Regional Medical Center
Mechanicsville, Virginia, 23116
Contact: Site Public Contact 804-893-8611 Melissa_Godsey@bshsi.org
Principal Investigator: William J. Irvin
Bon Secours Saint Francis Medical Center
Midlothian, Virginia, 23114
Contact: Site Public Contact 804-893-8611 Melissa_Godsey@bshsi.org
Principal Investigator: William J. Irvin
Southwest VA Regional Cancer Center
Norton, Virginia, 24273
Contact: Site Public Contact 423-578-8538 justin.reynolds@wellmont.org
Principal Investigator: Asheesh Shipstone
Bon Secours Saint Mary's Hospital
Richmond, Virginia, 23226
Contact: Site Public Contact 804-893-8611 Melissa_Godsey@bshsi.org
Principal Investigator: William J. Irvin
Virginia Cancer Institute
Richmond, Virginia, 23230
Contact: Site Public Contact 804-287-3000 david.trent@comcast.net
Principal Investigator: Khalid Matin
VCU Massey Cancer Center at Stony Point
Richmond, Virginia, 23235
Contact: Site Public Contact 804-628-1939 mwellons@vcu.edu
Principal Investigator: Khalid Matin
Virginia Commonwealth University/Massey Cancer Center
Richmond, Virginia, 23298
Contact: Site Public Contact 804-628-1914 klcampbell@vcu.edu
Principal Investigator: Khalid Matin
VCU Community Memorial Health Center
South Hill, Virginia, 23970
Contact: Site Public Contact 434-774-2442 sherman.baker@vcuhealth.org
Principal Investigator: Khalid Matin
Shenandoah Oncology PC
Winchester, Virginia, 22601
Contact: Site Public Contact 540-662-1108 William.Houck@usoncology.com
Principal Investigator: Khalid Matin
Harrison HealthPartners Hematology and Oncology-Bremerton
Bremerton, Washington, 98310
Contact: Site Public Contact 308-398-6518 clinicaltrials@sfmc-gi.org
Principal Investigator: Richard L. Deming
Jefferson Healthcare
Port Townsend, Washington, 98368
Contact: Site Public Contact 360-344-3091
Principal Investigator: Nicholas DiBella
Virginia Mason Medical Center
Seattle, Washington, 98101
Contact: Site Public Contact 206-342-6954 vmmc.cancer_clinical_research@VirginiaMason.org
Principal Investigator: Hagen F. Kennecke
Seattle Cancer Care Alliance
Seattle, Washington, 98109
Contact: Site Public Contact 800-804-8824
Principal Investigator: Stacey A. Cohen
Kaiser Permanente Washington Active, not recruiting
Seattle, Washington, 98112
Swedish Medical Center-First Hill
Seattle, Washington, 98122-4307
Contact: Site Public Contact 206-215-3086 PCRC-NCORP@Swedish.org
Principal Investigator: Alison K. Conlin
Seattle Cancer Care Alliance at Northwest Hospital
Seattle, Washington, 98133
Contact: Site Public Contact 206-606-5800
Principal Investigator: Stacey A. Cohen
United Hospital Center
Bridgeport, West Virginia, 26330
Contact: Site Public Contact 304-293-7374 cancertrialsinfo@hsc.wvu.edu
Principal Investigator: Shalu Pahuja
West Virginia University Charleston Division
Charleston, West Virginia, 25304
Contact: Site Public Contact 304-388-9944
Principal Investigator: Steven J. Jubelirer
Edwards Comprehensive Cancer Center
Huntington, West Virginia, 25701
Contact: Site Public Contact 304-399-6617
Principal Investigator: Maria R. Tria Tirona
Langlade Hospital and Cancer Center
Antigo, Wisconsin, 54409
Contact: Site Public Contact 715-623-9869 Juli.Alford@aspirus.org
Principal Investigator: Harish G. Ahuja
ThedaCare Regional Cancer Center
Appleton, Wisconsin, 54911
Contact: Site Public Contact 920-364-3605 ResearchDept@thedacare.org
Principal Investigator: Xin Yao
Duluth Clinic Ashland
Ashland, Wisconsin, 54806
Contact: Site Public Contact 218-786-3308 CancerTrials@EssentiaHealth.org
Principal Investigator: Bret E. Friday
Ascension Southeast Wisconsin Hospital - Elmbrook Campus
Brookfield, Wisconsin, 53045
Contact: Site Public Contact 414-635-6420 AWRI.Inquiry@Ascension.org
Principal Investigator: Francis J. Cuevas
Aurora Cancer Care-Southern Lakes VLCC
Burlington, Wisconsin, 53105
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
Marshfield Medical Center-EC Cancer Center
Eau Claire, Wisconsin, 54701
Contact: Site Public Contact 800-782-8581 oncology.clinical.trials@marshfieldresearch.org
Principal Investigator: Isaac K. Yeboah
Mayo Clinic Health System-Eau Claire Clinic
Eau Claire, Wisconsin, 54701
Contact: Site Public Contact 855-776-0015
Principal Investigator: Frank A. Sinicrope
Aurora Health Center-Fond du Lac
Fond Du Lac, Wisconsin, 54937
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
Ascension Saint Francis - Reiman Cancer Center
Franklin, Wisconsin, 53132
Contact: Site Public Contact 414-635-6420 AWRI.Inquiry@Ascension.org
Principal Investigator: Francis J. Cuevas
Aurora Health Care Germantown Health Center
Germantown, Wisconsin, 53022
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
Aurora Cancer Care-Grafton
Grafton, Wisconsin, 53024
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
Saint Vincent Hospital Cancer Center Green Bay
Green Bay, Wisconsin, 54301
Contact: Site Public Contact 920-433-8889 ewd_research_admin@hshs.org
Principal Investigator: Anthony J. Jaslowski
Saint Vincent Hospital Cancer Center at Saint Mary's
Green Bay, Wisconsin, 54303
Contact: Site Public Contact 920-433-8889 ewd_research_admin@hshs.org
Principal Investigator: Anthony J. Jaslowski
Aurora BayCare Medical Center
Green Bay, Wisconsin, 54311
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
Aurora Cancer Care-Kenosha South
Kenosha, Wisconsin, 53142
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
Gundersen Lutheran Medical Center
La Crosse, Wisconsin, 54601
Contact: Site Public Contact 608-775-2385 cancerctr@gundersenhealth.org
Principal Investigator: Michael O. Ojelabi
Mayo Clinic Health System-Franciscan Healthcare
La Crosse, Wisconsin, 54601
Contact: Site Public Contact 855-776-0015
Principal Investigator: Frank A. Sinicrope
Aurora Bay Area Medical Group-Marinette
Marinette, Wisconsin, 54143
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
Marshfield Medical Center-Marshfield
Marshfield, Wisconsin, 54449
Contact: Site Public Contact 800-782-8581 oncology.clinical.trials@marshfieldresearch.org
Principal Investigator: Isaac K. Yeboah
Aspirus Medford Hospital
Medford, Wisconsin, 54451
Contact: Site Public Contact 715-847-2353 Beth.Knetter@aspirus.org
Principal Investigator: Harish G. Ahuja
Aurora Cancer Care-Milwaukee
Milwaukee, Wisconsin, 53209
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
Aurora Saint Luke's Medical Center
Milwaukee, Wisconsin, 53215
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
Medical College of Wisconsin
Milwaukee, Wisconsin, 53226
Contact: Site Public Contact 414-805-3666
Principal Investigator: James P. Thomas
Aurora Sinai Medical Center
Milwaukee, Wisconsin, 53233
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
Marshfield Clinic-Minocqua Center
Minocqua, Wisconsin, 54548
Contact: Site Public Contact 800-782-8581 oncology.clinical.trials@marshfieldresearch.org
Principal Investigator: Isaac K. Yeboah
ProHealth D N Greenwald Center
Mukwonago, Wisconsin, 53149
Contact: Site Public Contact research.institute@phci.org
Principal Investigator: Timothy R. Wassenaar
Cancer Center of Western Wisconsin
New Richmond, Wisconsin, 54017
Contact: Site Public Contact 952-993-1517 mmcorc@healthpartners.com
Principal Investigator: Daniel M. Anderson
ProHealth Oconomowoc Memorial Hospital
Oconomowoc, Wisconsin, 53066
Contact: Site Public Contact 262-928-7878
Principal Investigator: Timothy R. Wassenaar
Saint Vincent Hospital Cancer Center at Oconto Falls
Oconto Falls, Wisconsin, 54154
Contact: Site Public Contact 920-433-8889 ewd_research_admin@hshs.org
Principal Investigator: Anthony J. Jaslowski
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, Wisconsin, 54904
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
Ascension All Saints Hospital
Racine, Wisconsin, 53405
Contact: Site Public Contact 414-635-6420 AWRI.Inquiry@Ascension.org
Principal Investigator: Francis J. Cuevas
Aurora Cancer Care-Racine
Racine, Wisconsin, 53406
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan, Wisconsin, 53081
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
Marshfield Clinic Stevens Point Center
Stevens Point, Wisconsin, 54482
Contact: Site Public Contact 800-782-8581 oncology.clinical.trials@marshfieldresearch.org
Principal Investigator: Isaac K. Yeboah
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Sturgeon Bay, Wisconsin, 54235-1495
Contact: Site Public Contact 920-433-8889 ewd_research_admin@hshs.org
Principal Investigator: Anthony J. Jaslowski
Aurora Medical Center in Summit
Summit, Wisconsin, 53066
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers, Wisconsin, 54241
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
ProHealth Waukesha Memorial Hospital
Waukesha, Wisconsin, 53188
Contact: Site Public Contact 262-928-7632
Principal Investigator: Timothy R. Wassenaar
UW Cancer Center at ProHealth Care
Waukesha, Wisconsin, 53188
Contact: Site Public Contact 262-928-5539 Chanda.miller@phci.org
Principal Investigator: Timothy R. Wassenaar
Aspirus Regional Cancer Center
Wausau, Wisconsin, 54401
Contact: Site Public Contact 877-405-6866
Principal Investigator: Harish G. Ahuja
Ascension Medical Group Southeast Wisconsin - Mayfair Road
Wauwatosa, Wisconsin, 53226
Contact: Site Public Contact 414-635-6420 AWRI.Inquiry@Ascension.org
Principal Investigator: Francis J. Cuevas
Aurora Cancer Care-Milwaukee West
Wauwatosa, Wisconsin, 53226
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
Aurora West Allis Medical Center
West Allis, Wisconsin, 53227
Contact: Site Public Contact 414-302-2304 ncorp@aurora.org
Principal Investigator: Adam P. Siegel
Marshfield Clinic - Weston Center
Weston, Wisconsin, 54476
Contact: Site Public Contact 800-782-8581 oncology.clinical.trials@marshfieldresearch.org
Aspirus UW Cancer Center
Wisconsin Rapids, Wisconsin, 54494
Contact: Site Public Contact 715-422-7718
Men or women age 18 years or older can participate if they:
- Have stage III colon cancer; tumors must originate in the colon
- Are Lynch syndrome patients having a in an MMR gene (, , , , );
- Have deficient (d) mismatch repair (dMMR)
- Show no evidence of spread to or disease
- Have had no prior medical therapy (chemotherapy, immunotherapy, biologic or ) or radiation therapy for the current colon cancer except for one cycle of mFOLFOX6
- Do not have active known autoimmune disease, including colitis, inflammatory bowel disease, rheumatoid arthritis, panhypopituitarism, adrenal insufficiency
- Do not have active hepatitis B or C
Patients will be excluded if they:
- Have active pulmonary disease with hypoxia (low oxygen levels)
- Are not MSI-High or dMMR
- Women who are pregnant