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Effect of Acupuncture on Memory and Thinking Difficulties after Breast Cancer


Acupuncture study for people with memory issues who completed treatment for stage 0-3 breast cancer

Inherited Cancer Registry (ICARE): Contribute to Research While Staying Informed

Surveys, Registries, Interviews
People with an inherited mutation or cancer in the family

Inherited Cancer Registry (ICARE): Contribute to Research While Staying Informed

ICARE is a registry of individuals interested in participating in inherited cancer research, through which data and samples are collected to contribute to research. Participants are also provided with ongoing research and clinical updates and informed about other research opportunities for which they might be eligible. Participants are recruited across the United States and beyond. There is no cost to participate, and all materials can be completed online.

Clinicaltrials.gov identifier: NCT03231891
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Survey for Individuals With a Hereditary Cancer Genetic Testing Result That was Later Reclassified


Survey for people whose genetic test results were reclassified

Survey For Individuals With A Hereditary Cancer Genetic Testing Result That Was Later Reclassified

Researchers are conducting an online survey to look into the personal experiences of people who received reclassfied genetic testing results for hereditary cancer gene mutations. 

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Adding Pembrolizumab to Olaparib to Treat Pancreatic Cancer in People with an Inherited BRCA Mutation

Treatment
Metastatic pancreatic cancer and a BRCA1 or BRCA2 mutation

Adding Pembrolizumab to Olaparib to Treat Pancreatic Cancer in People with an Inherited BRCA Mutation

This study is researching whether adding the immunotherapy drug Pembrolizumab (Keytruda) to the PARP inhibitor Olaparib (Lynparza) works better than olaparib alone in treating people with metastatic pancreatic cancer who also have an inherited BRCA1 or BRCA2 mutation.  

Clinicaltrials.gov identifier: NCT04548752
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Treatment with ATR Inhibitor for Advanced or Metastatic Solid Tumors

Treatment
Advanced solid tumors

Treatment with ATR Inhibitor for Advanced or Metastatic Solid Tumors

This study will look at how well a new oral targeted therapy known as an ATR inhibitor works on advanced or metastatic solid tumors with mutations in genes linked to DNA damage repair. The study will look at response to treatment with the drug ART0380 in combination with the chemotherapy agent, gemcitabine. 

Clinicaltrials.gov identifier: NCT04657068
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Nivolumab and Relatlimab in Advanced MSI-H Cancers Resistant to Prior PD-L1 Inhibitor

Treatment
Solid tumors that are MSI-High and resistant to prior immunotherapy

Nivolumab and Relatlimab in Advanced Mismatch Repair Deficient (dMMR/MSI-High) Cancers Resistant to Prior PD-L1 Inhibitor

The purpose of this study is to evaluate the safety, effectiveness, and tolerability of using the immunotherapy drugs nivolumab and relatlimab in patients with microsatellite instability high (MSI-H) solid tumors resistant to prior PD-L1 therapy.

Both nivolumab and relatlimab are a type of immunotherapy known as immune checkpoint inhibitors. Immune checkpoint inhibitors are drugs that prevent cancer cells from switching off immune cells. This allows the immune system to find, unmask and destroy cancer cells.

Clinicaltrials.gov identifier: NCT03607890
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Developing a Test for the Detection of Ovarian Cancer


Prevention study for women with a BRCA1 or BRCA2 mutation who are scheduled for risk-reducing salpingo-oophorectomy

Developing a Test for the Detection of Ovarian Cancer

The purpose of this study is to develop a test for early detection of ovarian cancer. Two patient populations are included in this study: women scheduled for surgery or testing for suspected but undiagnosed ovarian/fallopian tube cancer, and women with a BRCA1 or BRCA2 mutation who are scheduled for a risk-reducing salpingo-oophorectomy. The study will examine DNA from a washing of the uterus (womb) and proteins found in the blood to see if they can detect ovarian cancer.

Clinicaltrials.gov identifier: NCT04794322
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Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations

Treatment
Treatment study for people diagnosed with metastatic biliary tract (bile duct) cancer and who have an inherited or tumor mutation in ATM, BRCA 1/2, BRIP1, CHEK2, RAD51C, RAD51D, PALB2, PTEN, NBN and others

Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations

This study will look at how well the drug olaparib works in treating people who have been diagnosed with biliary tract (bile duct) cancer that has spread to other places in the body and who also have an inherited or tumor mutation in certain genes, including ATM, BRCA 1/2, BRIP1, CHEK2, RAD51C, RAD51D, PALB2, PTEN, NBN and others.  

Clinicaltrials.gov identifier: NCT04042831
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Research Opportunity for Previvors and their Romantic Partners


Interview for people with inherited mutations who had risk-reducing mastectomy and their partners

Research Opportunity for Previvors and their Romantic Partners

Researchers at the University of Kentucky are hoping to learn more about the relational experiences of individuals with hereditary breast cancer mutations who have navigated a double mastectomy while in a committed romantic relationship. They are particularly interested in the couples’ experience related to sexual intimacy before and after prophylactic surgical procedures. You do not have to live in Kentucky to participate. 

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Parent and Caregiver Perspectives on Cancer Screening for People With Intellectual Disabilities


Survey for parents and caregivers to share perspectives on cancer screening for people with intellectual disabilities

Cancer Screening for People With Intellectual Disability: Exploring Parent and Caregiver Perspectives

Our goal is to understand the experiences of people with intellectual disability in regard to screening for cancer, for example colonoscopies for colon cancer and mammograms for breast cancer. For people not being screened, we hope to learn about any barriers faced.

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Validating a Blood Test for Early Ovarian Cancer Detection in High-risk Women and Families

Prevention
Screening study for women with a BRCA1, BRCA2, BRIP1, PALB2, RAD51C, RAD51D, PMS2, MLH1, MSH2, MSH6, or EPCAM mutation

Validating a Blood Test for Early Ovarian Cancer Detection in High-risk Women and Families: MicroRNA Detection Study (MiDE)

The goal of MiDe is to develop a clinical diagnostic test to detect early onset ovarian cancer, as currently, there are no good screening or early detection tests available. Participants can be expected to provide up to 4 tubes of blood every 6 months for up to 5 years. We can collect these samples through mobile phlebotomy all around the US. The study is enrolling people with an inherited mutation with a gene linked to ovarian cancer, such as BRCA1, BRCA2, BRIP1, PALB2, RAD51C, RAD51D, PMS2, MLH1, MSH2, MSH6, or EPCAM. Participants can be expected to provide up to 4 tubes of blood every 6 months for up to 5 years. We can collect these samples through mobile phlebotomy all around the US.

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Comparing the Safety and Effectiveness of a New Hormonal Therapy in Patients with HER2-Negative, ER-Positive Early Breast Cancer


Treatment study for people with early-stage breast cancer

Comparing the Safety and Effectiveness of a New Hormonal Therapy in Patients with HER2-Negative, ER-Positive Early Breast Cancer

This study is comparing safety and effectiveness of a new drug called giredestrant compared to standard hormone therapy in people with early-stage, ER-positive breast cancer. 

Clinicaltrials.gov identifier: NCT04961996
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Survey for People who Received a Negative Genetic Test Result for a Known Mutation in the Family


People who received a negative genetic test result

What Factors Influence Survivors’ Guilt in Individuals Who Tested Negative for a Known Hereditary Cancer Syndrome?

This study is to understand the experiences of people who have received a negative genetic test result for a known familial hereditary cancer mutation (i.e., a “true negative” result) and determine what factors influence the presence of survivors’ guilt in these individuals.

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Blood Tests to Measure Ovarian Reserves in Women with a BRCA Mutation or Women Treated for Early-Stage Breast Cancer

Prevention
Study for premenopausal women with early-stage breast cancer and high-risk women with BRCA mutations and no evidence of breast or ovarian cancer

Serum Biomarkers to Characterize the Effects of Therapy on Ovarian Reserve in Premenopausal Women With Early-stage Breast Cancer or BRCA Mutations

The purpose of this study is to see how cancer treatment affects the ovaries, such as the impact on conceiving a child or the early onset of menopause. Comparatively, the study will also look at high-risk women with BRCA1/2 mutations (and no evidence of breast or ovarian cancer).

The study will check blood levels of hormones that the ovaries produce and will use questionnaires to gather information about participant menstrual cycles, health, and pregnancies. 

Clinicaltrials.gov identifier: NCT00823654
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Talazoparib for People with Metastatic Breast Cancer Who Have Acquired (Somatic) BRCA Mutations

Treatment
This is a study for people with metastatic breast cancer without a known mutation in BRCA1 or BRCA2, who learn they have a BRCA1 or BRCA2 acquired tumor mutation (somatic mutation) found through liquid biopsy

Talazoparib for People with Metastatic Breast Cancer Who Have Acquired (Somatic) BRCA Mutations

This is a study for patients with metastatic breast cancer who do not have an inherited mutation in BRCA1 or BRCA2 but who are are found to have a BRCA1 or BRCA2 acquired tumor mutation (somatic mutation) found through liquid biopsy. Patients are treated with talazoparib, a well-tolerated oral PARP inhibitor that targets the BRCA1and BRCA2 mutation to determine whether this treatment (which is already approved for germline BRCA1 and BRCA2 carriers) is effective in this population.

Clinicaltrials.gov identifier: NCT03990896
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A Randomized Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Metastatic Breast, Ovarian, Prostate and Pancreatic Cancer Patients (E-Reach)

Treatment
A study looking at using web options to increase access to testing AND patients in this study can get genetic counseling and testing in their home

A Randomized Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Metastatic Breast, Ovarian, Prostate and Pancreatic Cancer Patients

Genetic testing can be helpful to identify potential targeted treatments for some patients with metastatic cancer. But some patients have a hard time getting easy and fast testing. This study is looking at using web options to increase access to testing AND patients in this study can get genetic counseling and testing in their home! 

Clinicaltrials.gov identifier: NCT04353973
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Pancreatic Cancer Screening Study for High Risk People

Prevention
Screening study to detect pancreatic cancer and precancer in people with either a strong family history of pancreatic cancer, or an inherited mutation associated with pancreatic cancer risk

A Pancreatic Cancer Screening Study for High Risk Individuals

The purpose of this study is to screen and detect pancreatic cancer and precancer in people with either a strong family history of pancreatic cancer, or an inherited mutation associated with pancreatic cancer risk.

Magnetic Resonance Imaging (MRI) will be used to screen for early stage pancreatic cancer. Participants will also be asked to donate a blood sample at specific intervals for the creation of a blood bank necessary for the development of a blood-based screening test for pancreatic cancer. 

Clinicaltrials.gov identifier: NCT03250078
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Comparing Three Drugs as Late-Stage Treatment for Individuals with Metastatic Colorectal Cancer


treatment study for people with metastatic colorectal cancer

Comparing Three Drugs as Late-Stage Treatment for Individuals with Metastatic Colorectal Cancer

This study is being done to look at how well a combination of three drugs works for the treatment of metastatic colorectal cancer in patients who have had their cancer come back or get worse after treatment. The study is open to people who have had at least one, but no more than four courses of treatment in the metastatic setting. 

Clinicaltrials.gov identifier: NCT05328908
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Connect My Variant

Surveys, Registries, Interviews
Study for people with an inherited mutation to help them talk with relatives about their family history and genetic test results, connect them to others with the same variant and to their family trees

Connect My Variant

Researchers at the University of Washington (UW) are recruiting participants with known inherited mutation.  We aim to help participants talk to relatives (both immediate and distant) about their family history and genetic test results, to connect them with others who have the same variant, and to their family trees together.  The study provides tools and resources to help at-risk relatives get genetic testing through their own local doctors.

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Treatment for Advanced or Recurrent  Endometrial Cancer


Comparing an Immunotherapy Drug, Pembrolizumab With Chemotherapy in Advanced or Recurrent Endometrial Cancer

Comparing an Immunotherapy Drug, Pembrolizumab With Chemotherapy in Advanced or Recurrent Endometrial Cancer

This study is to test the safety and effectiveness of treatment with pembrolizumab, also known as Keytruda, compared to a combination of chemotherapy treatments in women with deficient mismatch repair (dMMR) advanced or recurrent endometrial cancer who had not previously been treated with prior chemotherapy treatments. The study is being conducted to determine if  pembrolizumab is better than the combined chemotherapy in terms of Progression Free Survival (PFS).

 

Clinicaltrials.gov identifier: NCT05173987
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Testing Immunotherapy Treatments for Recurrent Endometrial Cancer


Treatment study for people with endometrial cancer that has returned

Testing Immunotherapy Treatments for Recurrent Endometrial Cancer

This study tests the combination of two immunotherapy drugs compared to one immunotherapy drug to shrink tumors in patients with endometrial cancer that has returned after not being detected for a period of time (recurrent). The study is enrolling people with a biomarker known as dMMR.

Clinicaltrials.gov identifier: NCT05112601
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Study for People with Unexpected Genetic Results

Prevention
This study is recruiting people who received unexpected genetic test results about their cancer risk after having genetic testing done for some other reason

Genomic Services Research Program Study for People with Unexpected Genetic Results

A new study is recruiting people who received unexpected genetic test results about their cancer risk after having genetic testing done for some other reason.

This is a study of people with "secondary results” from genetic testing. Secondary results are unexpected. They are not related to the reason the person had the genetic test but are shared because they may be very important to the person’s health. Most secondary results have to do with high risks for health problems that can be treated or prevented. Many of these results are related to cancer risk. If you think you have received a secondary result, you may be eligible to join this study.

Clinicaltrials.gov identifier: NCT02595957
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Talking to Employers and Medical Staff About Breast Cancer Treatment and Your Job

Quality of Life
Study for people diagnosed with cancer to help them navigate wok-related issues

Talking to Employers and Medical Staff About Breast Cancer Treatment and Your Job (TEAMWork Study)

The goal of this study is to improve a tool that helps cancer patients navigate work-related issues. Researchers are testing an early version of a mobile app designed to help breast cancer patients keep their jobs. The app – called TEAMWork (Talking to Employers And Medical staff about Work) – provides advice for patients who need to talk to their employers about treatment or their medical team about work. Researchers want patient feedback on what aspects of the app work well and what can be better.  

Clinicaltrials.gov identifier: NCT03572374
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Investigating the Use of Self-Acupressure for Fatigue in Ovarian Cancer Survivors


University of Michigan researchers are investigating the use of self-acupressure for fatigue in ovarian cancer survivors.

Investigating the Use of Self-Acupressure for Fatigue in Ovarian Cancer Survivors

Study using acupressure for people experiencing fatigue after ovarian cancer treatment.

Clinicaltrials.gov identifier: NCT03763838
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Hereditary Breast Cancer Treatment Study (Treatment Study)

Surveys, Registries, Interviews
The Treatment Study is an international research study to better understand breast cancer treatment among individuals with ATM, CHEK2 and PALB2 gene mutations

Hereditary Breast Cancer Treatment Study (Treatment Study)

The Treatment Study is an international research study to better understand breast cancer treatment among individuals with ATM, CHEK2 and PALB2 gene mutations. Participants are asked to complete online or paper study questionnaires (every two years for 10 years) and share their family history, medical, and genetics records.

 

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ELLIE's Project

Quality of Life
A survey to gain a better understanding of the baseline lifestyle factors related to nutrition and physical activity in people with a hereditary cancer gene mutation

Energetics and Lifestyle in Inherited Syndromes (ELLIE’s Study)

ELLIE’s Project is designed to look at factors that may affect cancer risk in people with inherited mutations linked to cancer. The study will look at weight, Body Mass Index, metabolism, dietary habits and activity level over the course of people’s life-time. ELLIE’s Project aims to gain a better understanding of the baseline lifestyle factors related to nutrition and physical activity in people with a hereditary cancer gene mutation.

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Physical Activity at Home for Relief from Neuropathy Caused by Taxanes in People with Breast Cancer


Quality of life study for breast cancer patients experiencing neuropathy from chemotherapy

Study of Physical Activity at Home for Relief from Neuropathy Caused by Taxanes in People with Breast Cancer

Chemotherapy-induced peripheral neuropathy (CIPN) symptoms include numbness combined with tingling sensations, persistent shooting, stabbing, or burning pain even in the absence of an obvious cause, lower extremity muscle weakness, and impaired balance. Resistance exercise has shown promising results; however, the effect of exercise on CIPN remains understudied. This study will look at the effects of gain and balance training and resistance exercise (using bands) on gait, balance, and lower extremity muscle strength after a 16-week home-based exercise program compared to educational materials without an exercise program.

 

Clinicaltrials.gov identifier: NCT04621721
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Identification and Analysis of Families With Genetic Susceptibility To Cancer Registry

Surveys, Registries, Interviews
Registry for people with an inherited mutation in BRCA1 or BRCA2, or a BRCA1 or BRCA2 variant of uncertain significance, a gene mutation linked to a Lynch syndrome or an inherited mutation in another cancer risk gene

Identification and Analysis of Families With Genetic Susceptibility To Cancer Registry

The research laboratory at the Abramson Cancer Center is studying genetic sources of cancer risk and currently has one of the largest collections (also called a registry) of families with known or suspected risk in the world. A number of research projects are performed in collaboration with this registry. Research participants receive a numerical identification number that protects their privacy. Collaborating centers do not have access to personal identifiers such as names and dates of birth because only the numerical identifiers are shared.

 

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Chemotherapy, Bevacizumab, and/or Atezolizumab for dMMR / MSI-H Metastatic Colorectal Cancer (COMMIT Study)

Treatment
This is a treatment study is for people with metastatic colorectal cancer

Chemotherapy, Bevacizumab, and/or Atezolizumab for Patients With Deficient DNA Mismatch Repair (dMMR or MSI-H) Metastatic Colorectal Cancer, the COMMIT Study

This study is for people with metastatic colorectal cancer. The study will compare how well treatment with a combination of chemotherapy agents and an immunotherapy agent works compared with treatment using an immunotherapy agent alone. This study is focused on patients who are determined to be mismatch-repair deficient (dMMR) or have an MSI-H diagnosis, which are commonly seen in people with Lynch syndrome.

Clinicaltrials.gov identifier: NCT02997228
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Women's Sexuality After Gynecological Cancer Treatments


Virtual or in-person interview to share personal experiences of sexuality after gynecological cancer treatment(s).

Women's Sexuality After Gynecological Cancer Treatments

Explore women's lived experiences of sexuality after gynecological cancer treatment(s).

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Additional Results on Clinicaltrials.gov
1000 results
Clinical Trial Official Title
NCT05941520 Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer
NCT05107674 A Study of NX-1607 in Adults With Advanced Malignancies
NCT05691465 Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells
NCT06488365 In Vivo Liquid Biopsy of Melanoma (Cytophone)
NCT06904365 Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women
NCT06465966 UFPTI 2403-PR12: Real-Time Volumetric Ionizing Radiation Acoustic Imaging for In-vivo Proton Treatment Monitoring in Pencil-Beam Scanning
NCT04812366 Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer
NCT06378866 Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial
NCT02207465 A Phase I Dual Dose Escalation Study of Radiation and Nab-Paclitaxel in Patients With Unresectable and Borderline Resectable Pancreatic Cancer
NCT04329065 Concurrent WOKVAC Vaccination, Chemotherapy, and HER2-Targeted Monoclonal Antibody Therapy Before Surgery for the Treatment of Patients With Breast Cancer
NCT06376565 Improving Colonoscopy Surveillance for Patients with High Risk Colon Polyps
NCT06090266 A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents
NCT05693766 Gene Signatures to Guide HR+MBC Therapy in a Diverse Cohort
NCT05327465 Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy
NCT05800665 A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer
NCT05579366 Rinatabart Sesutecan (Rina-S) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
NCT06833866 Phase I Trial of 5-Fluorouracil (5FU) -Based Therapy in Combination With Hydroxytyrosol (HT) in Patients With Advanced or Metastatic Colorectal Cancer
NCT05325866 A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression
NCT05696626 Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
NCT00899626 Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples from Colorectal Cancer Patients
NCT05289466 Oncoplastic Partial Mastectomy With Intraoperative Radiation Therapy (IORT) in Early Stage Breast Cancer Patients With Prior History of Chest Wall Radiation.
NCT04872166 A Study of BTX-A51 in People With Advanced Solid Tumor and Breast Cancer
NCT02871726 Transrectal Ultrasound Robot-Assisted Prostate Biopsy
NCT06130826 Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer
NCT03769766 Trial of Curcumin to Prevent Progression of Low-risk Prostate Cancer Under Active Surveillance
NCT04140526 Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC
NCT06420726 Resistance Exercise and Creatine in Colorectal Cancer
NCT06633926 Integrative Approaches for Cancer Survivorship (IACS3)
NCT06423326 Gemcitabine, Cisplatin and Nab-Paclitaxel As Neoadjuvant Treatment for Patients with Resectable or Borderline Resectable Pancreatic Cancer
NCT05391126 GENOCARE: a Prospective, Randomized Clinical Trial of Genotype-Guided Dosing Versus Usual Care
NCT05990426 Alternate Day Fasting After Surgery for Patients Undergoing Chemotherapy
NCT05592626 A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants with Advanced Solid Tumors
NCT05183126 Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With Cancer
NCT06590857 Trial of 225Ac-DOTATATE (RYZ101) in Subjects with ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.
NCT06106282 Breast Cancer Survivors Who Experience Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)
NCT05653882 A Study Evaluating AB248 Alone or in Combination with Pembrolizumab in Adult Patients with Solid Tumors
NCT06428682 Role of TXA in Patients Undergoing Breast Free Flap Reconstruction
NCT02451982 Platform Study of Neoadjuvant and Adjuvant Immunotherapy for Patients With Resectable Adenocarcinoma of the Pancreas
NCT04074720 Prospective Breast Cancer Biospecimen Collection
NCT05634720 Hepatic Artery Chemotherapy for Patients With Localized Pancreas Cancer
NCT06412120 Study Evaluating Safety, Tolerability, and Metabolism of Niraparib
NCT05825482 Breast Margin Study: Routine Cavity Shave Margins Vs. Selective Margins Using Savi Scout®
NCT05958082 Utilization of Educational Interventions in Completion of Genetic Testing in Black Patients with High-Risk Prostate Cancer
NCT06202820 CV CARE: CardioVascular Care in PC Patients
NCT05485974 A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation
NCT05799274 Safety of RAD301 in Healthy Human Volunteers and Patients with Pancreatic Cancer
NCT02918474 Decision Making Tool in Supporting Decision Making in Contralateral Prophylactic Mastectomy in Patients With Newly Diagnosed Breast Cancer
NCT04421820 BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours
NCT05470920 Genetic Testing Decision Aid
NCT06340620 EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope
NCT05828082 Testing the Effect of M1774 on Hard-to-Treat Refractory SPOP-mutant Prostate Cancer
NCT05568420 A Study of the Possible Effects of Medication on Young Onset Colorectal Cancer (YOCRC)
NCT06545682 Phase Ib Study of AlpeliSib With PEmbroLizumab in Patients With mEtastatic Breast caNcer or melanomA (SELENA)
NCT05563220 Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Patients With Metastatic Breast Cancer
NCT04796220 Focused Ultrasound and Gemcitabine in Breast Cancer
NCT06268665 Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy
NCT06744465 NearWave Optical Molecular Monitoring
NCT05851365 Magnetic Resonance (MR) Imaging With Hyperpolarized Bicarbonate (13C) to Measure Tissue pH in Prostate Cancer
NCT00756665 Prostate Active Surveillance Study
NCT05156866 First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer
NCT06721065 A Study of Language Interpretation Solutions for People With Breast Cancer
NCT04503265 A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies
NCT06799065 First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer
NCT06549465 Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer (CRPC)
NCT04756765 Talazoparib Monotherapy in PALB2 Mutation Associated Advanced Breast Cancer
NCT04275557 Using Radiogenomics to Predict Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas
NCT05952557 An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)
NCT05047926 Prehabilitation for Stage IIIC-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients
NCT06743126 SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma
NCT06402357 High Intensity Focused Ultrasound in Prostate Cancer
NCT05227326 AOH1996 for the Treatment of Refractory Solid Tumors
NCT02610426 Whole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Congestive Heart Failure Receiving Therapy for Breast Cancer
NCT06817226 BREAST Choice Decision Tool R21
NCT06324357 Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
NCT05573126 Phase 1/2 Study to Evaluate Vosilasarm (EP0062) as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer
NCT02595957 Genomic Services Research Program
NCT06533826 TReatment of ADC-Refractory Breast CancEr with Dato-DXd or T-DXd: TRADE DXd
NCT05842057 Human Amnion Membrane Allograft and Early Return of Erectile Function After Radical Prostatectomy
NCT06253520 Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer
NCT06639074 Folate Receptor Alpha Dendritic Cells (FRαDCs) or Placebo for the Treatment of Patients with Stage III or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer, FAROUT Trial
NCT05764720 Stereotactic Adaptive Radiation Therapy of Borderline Resectable Pancreatic Cancer an Individualized Approach
NCT05305365 Study Assessing QBS72S for Treating Brain Metastases
NCT05929820 Impact of Protect Your Colon™ on CRC Screening
NCT05115474 Study of Screening Brain MRIs in Stage IV Breast Cancer
NCT05268666 A Study of Orally Administered JBI-802, an LSD1/HDAC6 Inhibitor, in Patients With Advanced Solid Tumors
NCT04841148 Avelumab or Hydroxychloroquine with or Without Palbociclib to Eliminate Dormant Breast Cancer
NCT06483048 MUC1-Activated T Cells for the Treatment of Relapsed and Resistant Ovarian Cancer
NCT06710548 REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors
NCT04768426 Serial Circulating Tumor DNA (ctDNA) Monitoring During Adjuvant Capecitabine in Early Triple-negative Breast Cancer
NCT06425926 Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors
NCT06026657 Gemcitabine and Ex Vivo Expanded Allogenic Universal Donor, TGFβi Natural Killer (NK) Cells with or Without Naxitamab (Danyelza) for the Treatment of Patients with Metastatic, GD2 Expressing, HER2 Negative Breast Cancer
NCT05461430 Mass Response of Tumor Cells As a Biomarker for Rapid Therapy Guidance (TraveraRTGx)
NCT05870748 REFRaME-O1: A Study to Investigate the Efficacy and Safety of Luveltamab Tazevibulin Versus Investigator's Choice (IC) Chemotherapy in Women With Ovarian Cancer (Including Fallopian Tube or Primary Peritoneal Cancers) Expressing FOLR1
NCT05968157 MIRAI-MRI: Comparing Screening MRI for Patients at High Risk for Breast Cancer Identified by Mirai and Tyrer-Cuzick
NCT04196257 BP1001-A in Patients With Advanced or Recurrent Solid Tumors
NCT06044857 PSMA PET Response Guided SabR in High Risk Pca
NCT04616248 In Situ Immunomodulation with CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients W/ Unresectable and Metastatic Solid Tumors
NCT04678648 A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies
NCT03972657 A Trial to Find Out if REGN5678 is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors
NCT05744557 Vapocoolant Analgesia for Breast Lymphoscintigraphy
NCT06068257 Tumor-Derived FGF19
NCT03558048 The Effect of IBD Flares on Serum PSA
NCT04565457 A Pilot Study Evaluating the Effect of 2D Antiscatter Grids on CBCT Image Quality
NCT01042548 Proteomics and Radiomics Research of Breast Cancer Markers in Tissue, Interstitial Fluid and Serum
NCT03659448 Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer
NCT04991948 Study of Pembrolizumab Treatment After CYAD-101 With FOLFOX Preconditioning in Metastatic Colorectal Cancer
NCT05766748 Study of Effect of Azeliragon in Patients Refractory to Prior Treatment of Metastatic Pancreatic Cancer
NCT05721248 STOP-HER2: Stopping Trastuzumab in HER2+ MBC
NCT02016248 Evaluation of CyberKnife Stereotactic Radiotherapy in Prostate Cancer
NCT05948657 Evaluation of Prostate Specific Membrane Antigen Positron Emission Tomography-Computed Tomography in Active Surveillance for Prostate CancEr
NCT04523857 ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast Cancer
NCT05085548 ProAgio in Previously Treated Advanced Pancreatic Cancer and Other Solid Tumor Malignancies
NCT06249048 Phase 1/2 Study of Intratumoral Injection of STX-001 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab
NCT04590326 A Trial to Find Out How Safe REGN5668 is and How Well it Works When Given With Either Cemiplimab or REGN4018
NCT00830557 Collecting Medical Information and Tissue Samples from Patients with Pancreatic Cancer or Other Pancreatic Disorders
NCT02910557 Postmarketing Prospective Study of Melanoma Patients Treated With IMLYGIC® to Characterize Risk of Herpetic Infection
NCT05123482 A Phase I/IIa Study of AZD8205 Given Alone or in Combination With Anticancer Drugs, in Participants With Advanced or Metastatic Solid Malignancies
NCT05961982 Evaluation of Endoscopic Ultrasound-Guided Radiofrequency Ablation for the Management of Pancreatic Tumors, ERASE Study
NCT06671782 A Study of a Pelvic Floor Muscle Exercise Program Before and After Radical Prostatectomy
NCT05464082 Functional Precision Oncology to Predict, Prevent, and Treat Early Metastatic Recurrence of TNBC
NCT03866382 Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
NCT05803382 Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers
NCT05669482 Study of Avutometinib (VS-6766) +Defactinib With Gemcitabine and Nab-paclitaxel in Patients With Pancreatic Cancer
NCT05746182 Genetic Predisposition Testing Program for Pancreatic Neuroendocrine Neoplasms
NCT03995082 Breast Cancer Patient Engagement With Patient Reported Outcome Measure Survey
NCT05806931 Sequential TAS-OX Alternating With TAS-IRI Plus Bevacizumab for Late-Line Metastatic Colorectal Cancer
NCT05034627 Calaspargase Pegol-Mnkl and Cobimetinib for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer
NCT04240327 Marker Driven Selection of Patients for Prostate Biopsy and Management
NCT03073694 Comparing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) Using Mitomycin-C Versus Melphalan for Colorectal Peritoneal Carcinomatosis
NCT06179160 A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
NCT05665660 Developing and Evaluating Culturally Relevant Interventions to Improve Breast Cancer Screening
NCT02861573 Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)
NCT04104776 A Study of CPI-0209 in Patients With Advanced Solid Tumors and Lymphomas
NCT06339827 ASk Questions in GYnecologic Oncology (ASQ-GYO)
NCT04666727 Role of Diet on the Microbiome of the Digestive System
NCT05546827 PRISM: Pre-Operative Radiotherapy and Immunotherapy for Sinonasal Melanoma
NCT06646627 Clinical Trial of Autologous B7-H3 CAR T Cells in Reoccurent Platinum-resistant Ovarian Tumors
NCT04569773 Choosing Ovarian Preservation or Removal Before Surgery for Endometrial Cancer
NCT04903873 A Study to Evaluate Safety, Efficacy, and Pharmacokinetics in Participants With Advanced Solid Tumors
NCT03861676 Image-guided Focal Brachytherapy Utilizing Combined 18F-DCFPyl PET/CT
NCT04808427 Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate Cancer
NCT04471727 A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001)
NCT02064673 Adjuvant Curcumin to Assess Recurrence Free Survival in Patients Who Have Had a Radical Prostatectomy
NCT06524973 Telehealth Self-Management Coaching Sessions to Improve Quality of Life in Pancreatic Cancer Survivors and Their Family Care Givers
NCT05440929 Evaluation of the Acceptability, Appropriateness, and Feasibility/Usability of a Metastatic Breast-cancer Specific Prognostic Calculator Among Clinicians
NCT05568680 SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma
NCT06267729 Study of AZD0754 in Participants With Metastatic Prostate Cancer
NCT03930680 Prevention of Heart Failure Induced by Doxorubicin With Early Administration of Dexrazoxane
NCT05272462 Oral Minoxidil for the Treatment of Recurrent Platinum Resistant Epithelial Ovarian Cancer
NCT03704662 Preoperative Fractionated Radiation Therapy Versus Stereotactic Body Radiation Therapy for Resectable or Borderline Resectable, or Locally Advanced Type A Pancreatic Adenocarcinoma
NCT05208762 A Study of SGN-PDL1V in Advanced Solid Tumors
NCT04423029 A Study of DF6002 Alone and in Combination With Nivolumab
NCT04919629 APL-2 and Pembrolizumab Versus APL-2, Pembrolizumab and Bevacizumab Versus Bevacizumab Alone for the Treatment of Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer and Malignant Effusion
NCT04562129 IL2 With Ipilimumab Followed by Nivolumab in Stage 3 or 4 Melanoma Patients
NCT06130280 A Study of Single Fraction Stereotactic Body Radiation Therapy (SBRT) Guided by Magnetic Resonance Imaging (MRI) in People With Liver Metastasis From Colorectal Cancer
NCT05544929 A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers
NCT05143229 Alpelisib And Sacituzumab Govitecan For Treatment Of Breast Cancer
NCT06121180 Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma
NCT06445062 Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
NCT04337580 Fatty Acid Synthase Inhibition in Castration Refractory Prostate Cancer
NCT06264180 VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs (IGNYTE-3)
NCT06413680 A First-In Human (FIH) Trial to Find Out if REGN10597 is Safe and How Well it Works for Adult Participants With Advanced Solid Organ Malignancies
NCT06651580 Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study
NCT05983380 The Effect of Hand Exercises on Upper Limb Volume, Quality of Life, and Hand Function in Breast Cancer Survivors
NCT05710380 MRI Risk Maps for Prostate Cancer Diagnosis Using Targeted Biopsy
NCT05704062 Quantitative MRI Assessment of Breast Cancer Therapy Response
NCT06022029 A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.
NCT04748380 Shared Decision-making and Colorectal Cancer Screening
NCT04356729 A Phase II Trial of PD-L1 Therapy Combined with Anti-VEGF Therapy in Unresectable or Metastatic Melanoma
NCT06708429 Lynch Syndrome X-Talk of Enteral Mucosa With Immune System
NCT05620329 UNC Pleural Fluid Registry
NCT03879629 Treating Breast Cancer Patients Undergoing Trastuzumab Treatment with Carvedilol to Reduce Incidence of Heart Failure
NCT05785780 Aim 3, Optimizing CRC Screening in Patients With Diabetes in Safety-net Primary Care Settings
NCT05645380 Neoadjuvant TIL- and Response-Adapted Chemoimmunotherapy for TNBC
NCT05735080 Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer
NCT04258280 Improving Genetic Counseling for BRCA+ Mothers
NCT04722692 Delayed Sentinel Lymph Node Biopsy in Ductal Cancer in Situ
NCT06548789 Neoadjuvant Immune Checkpoint Blockade + a Prebiotic Food-enriched Dietary Intervention to Optimize Immune Response in Melanoma: NEO-PreFED
NCT04324294 Contrast Enhanced Endoscopic Ultrasound in Pancreas Lesions
NCT05604560 A Neoadjuvant Study of Tislelizumab and SX-682 for Resectable Pancreas Cancer
NCT06056791 Study of INKmune in Patients With mCRPC (CaRe Prostate)
NCT05593094 A Phase 1 Trial of ZN-A-1041 Enteric Capsules or Combination in Patients With HER2-Positive Advanced Solid Tumors
NCT04878094 A Study of Intra-operative Imaging in Women With Ovarian Cancer
NCT05408260 A Study to Compare the Effectiveness of Two Types of Ultrasound Technologies in Women Who Have Had Breast Cancer
NCT04550494 Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations
NCT05478694 Outcomes of Focal Ablation for Prostate Cancer
NCT05562791 A Study of 68Gallium PSMA-PET/CT Scans in People With Bladder Cancer or Skin Cancer
NCT06396091 A Study of Zolbetuximab With Chemotherapy in Adults With Pancreatic Cancer
NCT05422794 Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer
NCT05040360 Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors
NCT02400060 Telephone-Based Intervention in Increasing Adherence to Adjuvant Hormonal Therapy in Patients with Breast Cancer
NCT05633160 64Cu-SAR-BBN and 67CU SAR-BBN for Identification and Treatment of Gastrin Releasing Peptide Receptor (GRPR)-Expressing Metastatic Castrate Resistant Prostate Cancer in Patients Who Are Ineligible for Therapy With 177Lu-PSMA-617 (COMBAT)
NCT05691491 Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness
NCT04930991 High Dose Omeprazole in Patients With Pancreatic Cancer
NCT05766891 Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer Surgery
NCT04815876 PReclude Infection EVEnts With No Prophylaxis Transperineal Biopsy 2
NCT04824027 Breast Elasticity Imaging During Neoadjuvant Chemotherapy
NCT00001276 Diagnosing and Treating Low Blood Sugar Levels
NCT06508827 Intravenous Iron in Combination with Standard of Care Immunotherapy in Melanoma
NCT05349227 Comprehensive Outcomes for After Cancer Health
NCT05812027 A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors
NCT06620627 Prospective Collection of Samples to Enable the Development of Natera Screening Assay for Early Cancer Detection
NCT06081127 Breast Cancer Pre-habilitation and Prospective Surveillance to Prevent, Detect, and Optimize Physical and Function
NCT04839991 Study of CB307 in Patients With Advanced and/or Metastatic PSMA-positive Tumours.
NCT03971591 Men Moving Forward: A Lifestyle Program for African-American Prostate Cancer Survivors
NCT05613894 Dose-Escalation Study of Cabozantinib in Combination With Lutetium-177 (177Lu)-PSMA-617 in Patients With Metastatic Castration-Resistant Prostate Cancer
NCT05910294 A Study to Prevent and Improve Sexual Health Concerns for People With Breast Cancer
NCT05608291 A Trial to See if the Combination of Fianlimab With Cemiplimab Works Better Than Pembrolizumab for Preventing or Delaying Melanoma From Coming Back After it Has Been Removed With Surgery
NCT06750094 A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
NCT05417594 Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
NCT05411094 Testing the Safety of the Anti-Cancer Drugs Durvalumab and Olaparib During Radiation Therapy for Locally Advanced Unresectable Pancreatic Cancer
NCT06686394 Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)
NCT06253494 Pembrolizumab, Lenvatinib and IL-15 Superagonist N-803 in Combination With HER2 Targeting Autologous Dendritic Cell (AdHER2DC) Vaccine in Participants With Advanced or Metastatic Endometrial Cancer
NCT04147494 Experimental PET Imaging Scans Before Cancer Surgery to Study the Amount of PET Tracer Accumulated in Normal and Cancer Tissues
NCT03485794 Collection of Blood in Studying Metabolites in Patients With Prostate Cancer
NCT06276491 Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors
NCT05629494 Anti-inflammatory Drugs and Serum Prostate-Specific Antigen Test
NCT05535894 Endoscopic Radiofrequency Ablation of Celiac Ganglion for Pain Management and Improvement of Quality of Life in Patients With Unresectable Pancreatic Cancer
NCT05483491 KK-LC-1 TCR-T Cell Therapy for Gastric, Breast, Cervical, and Lung Cancer
NCT05000294 Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
NCT05150691 A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors
NCT06608927 Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma
NCT06318273 A Study to Assess Adverse Events, and How Intravenously (IV) Infused ABBV-969 Moves Through the Bodies of Adult Participants With Metastatic Castration-Resistant Prostate Cancer
NCT05340673 Comparing Supplemental Topical Agents for the Treatment of Acute Radiation Dermatitis in Patients With Breast Cancer
NCT04175431 Prostate Specific Membrane Antigen (PSMA) or (FACBC) PET/CT Site-Directed Therapy for Treatment of Prostate Cancer, Flu-BLAST-PC Study
NCT05092373 Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax
NCT05319873 Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer
NCT05484973 Study to Assess the Ability of the Portable Scalp Cooling System (PSCS) to Prevent Hair Loss
NCT06471673 A Study of BRIA-OTS Cellular Immunotherapy in Metastatic Recurrent Breast Cancer
NCT06172127 PHESGO Maintenance After T-DXd Short Induction for HER2+ Unresectable Locally Recurrent or Metastatic Breast Cancer
NCT06599476 Rectal Spacers in Prostate Cancer Patients Undergoing Radiation Therapy
NCT05856773 Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy
NCT06402331 FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC)
NCT05556473 F-Tryptophan PET/CT in Human Cancers
NCT05903131 A Behavioral Intervention to Promote Primary Prevention and Uterine Preservation in Premenopausal Women With Obesity and Endometrial Hyperplasia
NCT04886531 Trial of Pre-operative Neratinib and Endocrine Therapy with Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers
NCT06294873 Stool Sample Collection Study
NCT04573231 Evaluation of PSMA in HER2- AR+ Metastatic Breast Cancer
NCT03562273 GammaPod Registry and Quality of Life Nomogram
NCT06450873 Turkey Tail Mushroom for Treating Post-Menopausal Women With HER2-Negative ER-Positive Breast Cancer Undergoing Surgery
NCT06593431 Extending Outcomes for Pancreas Cancer Patients With Nominal Oligometastatic Disease (EXPAND): A Randomized Phase III Trial
NCT03746431 A Phase 1/2 Study of [225Ac]-FPI-1434 Injection
NCT05611931 Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma
NCT05888831 A Study of BMS-986449 With and Without Nivolumab in Participants With Advanced Solid Tumors
NCT05497531 Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers
NCT05869682 Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy
NCT05994482 Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study
NCT04297020 Brain Health in Breast Cancer Survivors
NCT06146920 Use of Serial Plasma NGS as a New Efficacy Metric to Guide Immunotherapy Treatment Discontinuation
NCT03909282 Surgical Excision vs Neoadjuvant Radiotherapy+Delayed Surgical Excision of Ductal Carcinoma
NCT04771520 Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors
NCT06188520 A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors
NCT06636682 FK-PC101 as Adjuvant Therapy for Men With High-Risk Prostate Cancer
NCT02361320 Computed Tomography in Diagnosing Patients With Pancreatic or Hepatobiliary Cancer
NCT06545331 Study of XB010 in Subjects With Solid Tumors
NCT04406831 The Role of MicroRNA in the Diagnosis, Prognosis and Response to Treatment in Pancreatic Cancer
NCT05965180 Interstitial Assessment of Architectural Heterogeneity in Prostate Cancer Using a Fine Needle Photoacoustic Probe
NCT02926729 Real-Time Assessment Of Breast Cancer Lumpectomy Specimen Margins With Nonlinear Microscopy
NCT06194929 Defactinib and Avutometinib, With or Without Encorafenib, for the Treatment of Patients With Brain Metastases From Cutaneous Melanoma
NCT04662580 ARX517/JNJ-95298177 as Monotherapy or Combination Therapy in Subjects With Metastatic Prostate Cancer
NCT06673329 Brodalumab in the Treatment of Immune-Related Adverse Events
NCT03692429 alloSHRINK - Standard cHemotherapy Regimen and Immunotherapy With Allogeneic NKG2D-based CYAD-101 Chimeric Antigen Receptor T-cells
NCT04134780 Ultrasound Imaging and Spectroscopy as Early Indicators of Locally-Advanced Breast Cancer Response
NCT03151629 International Registry for Men With Advanced Prostate Cancer (IRONMAN)
NCT06638294 Study in Patients With Breast Cancer Leptomeningeal Metastasis
NCT05608694 MRI Screening in Men at High Risk of Developing Prostate Cancer
NCT06239194 Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
NCT05396794 Bariatric Education for Women With Obesity and Endometrial Cancer
NCT06432660 Eye Plaque Brachytherapy for Ocular Melanoma
NCT03876860 An Enhanced Vaginal Dilator to Reduce Radiation-Induced Vaginal Stenosis
NCT04134260 Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer
NCT05627960 First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor Malignancies
NCT00991094 Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated with Proton Therapy
NCT05969860 At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients with Advanced Cancer
NCT05586360 T-reg Function Changes: a Novel Immune Regulatory Effect Underlying Benefit of Statin Use on Lethal Prostate Cancer
NCT04329494 PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer
NCT06315491 A Study of CBX 12 in Subjects With Platinum Resistant or Refractory Ovarian Cancer
NCT06271291 Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts
NCT04614194 Single Cell Immune and Non-immune Correlates of Response to Neoadjuvant Abemaciclib
NCT06594991 A Study of Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma
NCT06411691 KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer
NCT06120491 Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents
NCT04473794 Diagnostic Strategies, Risk Assessment and Progression of Pancreatic Cysts
NCT05467891 Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer
NCT05959291 Discontinuation of Maintenance HER-2 Directed Therapy in Long-Term Survivors of Metastatic HER-2 Positive Breast Cancer
NCT04754191 Enfortumab Vedotin As Monotherapy in Patients with Metastatic Castration-Resistant Prostate Cancer
NCT04609592 Study of PRRT in Metastatic, World Health Organization (WHO) Grade 1 or 2, SSTR Positive, GEP-NET Who Are Candidates for Cytoreductive Surgery
NCT05846789 SOC Chemotherapy +/- Tocilizumab for Triple Negative and ER-low Breast Cancers
NCT05625529 ExoLuminate Study for Early Detection of Pancreatic Cancer
NCT04510129 A Multicenter Cancer Biospecimen Collection Study
NCT05919329 Evaluation of the Change in PSMA Expression in Prostate Cancer in Response to Hormonal Therapy
NCT06751329 A Study of DM002 in Patients With Advanced Solid Tumors
NCT06435429 A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer
NCT05496829 IMPACT Trial: Intervention to IMProve AdherenCe Equitably
NCT04294927 TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention
NCT06023576 A Study of Blood Pressure Control During Cancer Treatment
NCT03495427 PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men w/ High Decipher Test Scores
NCT01638676 A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients
NCT06312176 A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
NCT05477576 Study of RYZ101 Compared with SOC in Pts W Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy
NCT04709276 A Study of Chemoimmunotherapy for the Treatment of Men With Neuroendocrine or Aggressive Variant Metastatic Prostate Cancer
NCT04697576 Intralesional Influenza Vaccine for the Treatment of Stage I-IV Melanoma
NCT06780176 A Study of Breast Cancer Risk Factors and Outcomes of People in Florida
NCT04967976 Breast Mesh Used in Two-staged Breast Reconstruction
NCT04090567 Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast Cancer
NCT06046040 TmPSMA-02 in mCRPC
NCT05372640 Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors
NCT03564340 Study of REGN4018 Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers
NCT06342440 Early Detection of Advanced Adenomas and Colorectal Cancer
NCT05537740 A First-in-human Study to Learn How Safe the Study Drug BAY3375968, an Anti-CCR8 Antibody, is, When Given Alone or in Combination With Pembrolizumab, How it Affects the Body, How it Moves Into, Through, and Out of the Body, and to Find the Best Dose in Participants With Advanced Solid Tumors
NCT05242744 FTT PET/CT in Metastatic Prostate Cancer
NCT04956640 Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)
NCT02402244 Project: Every Child for Younger Patients With Cancer
NCT02584244 Feasibility of the LUM Imaging System for Detection of Gastrointestinal Cancers
NCT05968144 Towards Understanding Between ADT Treatment, Circadian Rhythm, and Physiological Responsiveness
NCT06849544 Phase II Trial to Investigate the Safety and Efficacy of Three Dosing Regimens of OTL78 Injection
NCT04475640 Cancer Genetic Testing in Ethnic Populations
NCT04879940 Phase II Study to Evaluate the Safety and Efficacy of Prostatic Artery Embolization
NCT05059444 ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
NCT05877144 LiSWT for Nerve Sparing Radical Prostatectomy ED
NCT03804944 Converting HR+ Breast Cancer Into an Individualized Vaccine
NCT04282044 Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies
NCT05130840 Monitoring for Cancer Spread to the Central Nervous System (CNS) in People With Breast Cancer
NCT05367440 Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer
NCT06595160 Association of Plant-based Diet and Gut Microbiome Signature with Response to Neoadjuvant Therapy in Pancreatic Ductal Adenocarcinoma
NCT05076760 MEM-288 Oncolytic Virus Alone and in Combination With Nivolumab in Solid Tumors Including Non-Small Cell Lung Cancer
NCT05020860 Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer
NCT06401889 Enhancing Skin Appearance and Quality of Life in Breast Cancer Survivors on Aromatase Inhibitor Therapy
NCT06485089 Effects of Tirzepatide on Blood, Imaging and Breast Tissue Biomarkers
NCT06171789 PRO1107 in Patients With Advanced Solid Tumors
NCT05896189 Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors
NCT06399276 4:3 Intermittent Fasting Intervention in Adults With Breast Cancer and Overweight or Obesity
NCT05698576 TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer
NCT04701476 TATE and Pembrolizumab (MK3475) in mCRC and NSCLC
NCT06152276 SafeHeal Diverting Ileostomy Pivotal Study
NCT06586957 A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors
NCT03568448 Monitoring Response to Neoadjuvant Chemotherapy in HER2 Negative Breast Cancer Using High-speed MR Spectroscopic Imaging
NCT04443348 Pre-op Pembro + Radiation Therapy in Breast Cancer (P-RAD)
NCT02632448 A Study of LY2880070 in Participants With Advanced or Metastatic Cancer
NCT05752448 Survivorship Care for Women Living With Ovarian Cancer: (POSTCARE-O)
NCT06137248 Study to Assess Colonic Microbiota Changes in Response to Energy Drink Consumption
NCT05464030 Anti-CEACAM5 ADC M9140 in Advanced Solid Tumors (PROCEADE-CRC-01)
NCT04084730 Study of 3-Day Partial Breast Radiation Therapy in Women with Breast Cancer
NCT03568630 Blood Markers of Early Pancreas Cancer
NCT04734730 Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer
NCT05283330 Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors
NCT06507930 The COMPASSION Study
NCT06307548 Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer
NCT05877430 Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer
NCT05037825 The Gut Microbiome and Immune Checkpoint Inhibitor Therapy in Solid Tumors
NCT05810025 FHIR-Enhanced RealRisks to Improve Accuracy of Breast Cancer Risk Assessments
NCT04360330 SABER Study for Selected Early Stage Breast Cancer
NCT06805825 A Study of the C-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced And/or Metastatic Solid Tumors Known to Express C-Kit
NCT05673148 Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, the ERASur Study
NCT04941430 7T MRI Scan for the Early Detection of Melanoma Brain Metastases
NCT06056830 Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants with High-risk Prostate Cancer Prior to Radical Prostatectomy
NCT03203525 Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer
NCT05746325 Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast Cancer
NCT06297525 Study of STP938 in Advanced Solid Tumours
NCT01937039 Johns Hopkins Breast Cancer Program Longitudinal Repository
NCT06065748 A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)
NCT05799248 Role of rhPSMA-7.3 PET/CT Imaging in Men With High-Risk Prostate Cancer Following Conventional Imaging and Associated Changes in Medical Management
NCT05669430 A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies
NCT05634525 Phase Ib Trial of the KRASG12C Inhibitor Adagrasib (MRTX849) in KRAS G12C Mutant Metastatic Pancreatic Cancer Patients
NCT06534125 Acutherapy to Prevent Aromatase Inhibitor-Associated Arthralgias in Non-Hispanic Black Postmenopausal Women with Early-Stage Breast Cancer
NCT06385925 A Study of TSN1611 Treating Patients with Advanced Solid Tumors Harboring KRAS G12D Mutation
NCT04263025 AMNIOX CORD Study - Radical Prostatectomy With and Without Cryopreserved Umbilical Cord Allograft
NCT06657222 First in Human Study of TUB-030 in Patients with Advanced Solid Tumors
NCT05896839 Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer
NCT06128525 Prostate Resection After Microwave Ablation (PRAMA)
NCT05928325 Geriatric Care Survivorship Intervention for Improving the Overall Health of Older Adults with Stage I-III Breast Cancer Who Have Completed Curative Treatment
NCT03589339 NBTXR3 Activated by Radiotherapy for Patients with Advanced Cancers Treated with an Anti-PD-1 Therapy
NCT05412225 A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer
NCT06492122 Study With [225Ac]Ac-FL-020 in mCRPC Participants
NCT05231122 Pembrolizumab Combined With Bevacizumab With or Without Agonist Anti-CD40 CDX-1140 for the Treatment of Patients With Recurrent Ovarian Cancer
NCT06030622 Phase 2A Pilot C3 Trial of Recurrent/Refractory Metastatic Advanced Pancreatic Cancer
NCT06040125 Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial
NCT03745326 Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients
NCT05045066 Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients
NCT05267626 Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer
NCT03090165 Ribociclib and Bicalutamide in AR+ TNBC
NCT03048266 Metabolomics and Genetic Diagnosing Pancreatic Neuroendocrine Tumors in MEN1 Patients
NCT04198766 Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
NCT05756166 Rintatolimod, Celecoxib and Interferon Alpha 2b With Pembrolizumab For the Treatment of Patients With Metastatic or Unresectable Triple Negative Breast Cancer
NCT05036226 COAST Therapy in Advanced Solid Tumors and Prostate Cancer
NCT05948826 First in Human Study of TORL-3-600 in Participants With Advanced Cancer
NCT06297265 Manual Lymphatic Drainage Breast Massage in Breast Cancer Patients After Breast Conserving Surgery
NCT06295965 Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers, CHANCES Study
NCT06734130 Adaptive Androgen Deprivation and Docetaxel in Metastatic Castration Sensitive Prostate Cancer
NCT03351348 Bupivacaine vs Placebo for Unilateral Mastectomy Surgical Site Post-operative Pain Control
NCT04052048 Active Surveillance SNEP Assay Registry Trial for Prostate Cancer
NCT04606030 LymphBridge: Surgical Evaluation for Breast Cancer-Associated Lymphedema (BioBridge)
NCT05538130 A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors
NCT06610825 Castrate Resistant Prostate Cancer Enhertu Therapy
NCT05053230 A Study Evaluating the Integrative Medicine at Home (IM@HOME) Program in People With Cancer
NCT03524430 RNA Disruption Assay (RDA)-Breast Cancer Response Evaluation for Individualized Therapy
NCT03767348 Study of RP1 Monotherapy and RP1 in Combination With Nivolumab
NCT04039230 Study to Evaluate Sacituzumab Govitecan in Combination With Talazoparib in Patients With Metastatic Breast Cancer.
NCT06605430 Medical Cannabis in Patients With Advanced Pancreatic Cancer
NCT05539430 Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma
NCT05868226 PRE-I-SPY Phase I/Ib Oncology Platform Program
NCT06275126 Optimizing Surgical Decisions in Young Adults With Breast Cancer
NCT04752826 BI-1808 As a Single Agent and with Pembrolizumab (KEYTRUDA® ) in Treatment of Advanced Malignancies(Keynote-D20)
NCT05879926 Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
NCT06518057 Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer
NCT06557148 A Study Comparing Cancer Imaging Approaches in People with Lobular Breast Cancer
NCT06336148 A Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid Tumors
NCT06358430 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)
NCT04346225 Magnetic Resonance Imaging (MRI) With Hyperpolarized Pyruvate (13C) as Diagnostic Tool in Advanced Prostate Cancer
NCT06044025 A Feasibility Study Evaluating a Role for Maintenance Therapy in Patients With Biochemically Progressive Castration Sensitive Prostate Cancer on Intermittent Androgen Deprivation Therapy
NCT06119425 Blood-Based Colorectal Cancer (CRC) Screening Implementation Into Clinical Practice Highlands
NCT06449222 Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination With Chemotherapy
NCT06870539 Feasibility of Saliva and Remote Monitoring of Active Cytomegalovirus (CMV) Infection and Symptoms During Ovarian Cancer Treatment
NCT04918186 Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian Cancer
NCT06171139 Tumor Genomic Pre-test Counseling Tool for Black or African-American Men With Prostate Cancer
NCT04797039 MRI-Guided Cryoablation for Focal Native Prostate Cancer
NCT06398639 Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer
NCT03333122 Assessment of Breast Cancer Patients Satisfaction and Health Related Quality of Life Outcomes
NCT05478239 ArtemiCoffee in Patients With Rising PSA
NCT05678322 Optimizing Timing of rhPSMA-7.3 (18F) for Assessing Site(s) of Recurrent Disease Following Radical Prostatectomy
NCT04871139 An Imaging Technology, Contrast-Enhanced Mammography, in Predicting Breast Cancer
NCT06479239 Study of EGFRBi Armed Fresh PBMC in Metastatic or Unresectable Pancreatic Cancer
NCT04511039 Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer
NCT03104439 Nivolumab and Ipilimumab and Radiation Therapy in MSS and MSI High Colorectal and Pancreatic Cancer
NCT06262139 Evaluation of a Targeted Magnetic Resonance Imaging Contrast Agent in Prostate Cancer Patients
NCT06129422 Safety, Tolerability, Pharmacokinetics, Radiation Dosimetry, and PET Imaging Properties of 89Zr-labeled hNd2 (NMK89) in Patients With Pancreatic Cancer
NCT05783622 Study of JANX008 in Subjects with Advanced or Metastatic Solid Tumor Malignancies
NCT05051722 Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer
NCT04633239 Testing the Addition of Abemaciclib to Olaparib for Women With Recurrent Ovarian Cancer
NCT01788839 Longitudinal Sexual and Reproductive Health Study of Women with Breast Cancer and Lymphoma
NCT00451022 Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies
NCT06022822 Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial
NCT01915225 Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer
NCT05400122 Natural Killer (NK) Cells in Combination with Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer
NCT05651022 Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors
NCT05553522 Tucatinib, Trastuzumab, and Capecitabine With SRS for Brain Metastases From HER-2 Positive Breast Cancer
NCT05223322 Understanding and Addressing Disparities in Cancer Therapy Induced Inflammation and Associated Endothelial Dysfunction
NCT04847063 Individualized Response Assessment to Heated Intraperitoneal Chemotherapy (HIPEC) for the Treatment of Peritoneal Carcinomatosis From Ovarian, Colorectal, Appendiceal, or Peritoneal Mesothelioma Histologies
NCT06059963 A Prospective, Multi-center, Observational Study for Signal-C Test Evaluation
NCT06115486 EXERT-BCH Exercise Regimen to Improve Muscle Mass After Treatment of Breast Cancer
NCT06300463 Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases
NCT05528263 Preventing Chemotherapy-Induced Peripheral Neuropathy With Acupuncture (PACT Trial)
NCT03677739 Young Melanoma Family Facebook Intervention or Healthy Lifestyle Facebook Intervention in Improving Skin Examination in Participants With Melanoma and Their Families
NCT06662786 A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
NCT05174286 Community Health Workers United to Reduce Colorectal Cancer and Cardiovascular Disease Among People at Higher Risk
NCT06384222 Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) for Response Monitoring to Neoadjuvant Abiraterone
NCT06388122 DiviTum®TKa: A Biomarker Assay for Efficacy in HR+ Metastatic Breast Cancer Patients
NCT03880422 Nutrition and Exercise Interventions in Reducing Androgen Deprivation Therapy-Induced Obese Frailty in Prostate Cancer Survivors
NCT05238922 Study of INCB123667 in Subjects With Advanced Solid Tumors
NCT06028022 Reishi Mushroom Extract for Fatigue And/or Arthralgias/myalgias in Patients with Breast Cancer on Aromatase Inhibitors
NCT03539822 Cabozantinib Plus Durvalumab with or Without Tremelimumab in Patients with Gastroesophageal Cancer and Other Gastrointestinal Malignancies
NCT02960022 A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study
NCT06879522 Maximizing Energy and Reducing Fatigue in Breast Cancer Survivors
NCT04430725 Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study
NCT06654622 Exosome-based Detection of Molecular Residual Disease in Stage II-III Colorectal Cancer
NCT05922930 Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells Delivered Intraperitoneally for the Management of Platinum Resistant Ovarian Cancer, Mesonephric-like Adenocarcinoma, and Pancreatic Cancer
NCT03147430 Early Detection of Breast Cancer in Women With Suspicious Mammograms
NCT06806930 Predicting Response to Neoadjuvant Endocrine Therapy (Neo-PREDICT)
NCT05488548 Dual BET and CBP/p300 Inhibitor in Patients With Targeted Advanced Solid Tumors and Hematological Malignancies
NCT06671730 Self-Determination Theory-informed Occupational Therapy Program to Increase Physical Activity Among Survivors of Breast Cancer
NCT04588025 Disposable Perfusion Phantom for Accurate DCE (Dynamic Contrast Enhanced)-MRI Measurement of Pancreatic Cancer Therapy Response
NCT06158139 Autologous CAR-T Cells Targeting B7-H3 in PDAC
NCT06055439 A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy
NCT06666439 Longitudinal Tumor Burden Quantification Using Circulating Tumor DNA in Metastatic Lobular Breast Cancer
NCT05832086 Intermittent Fasting Using a Fasting-Mimicking Diet to Improve Prostate Cancer Control and Metabolic Outcomes
NCT05720039 Robotic vs. Open NSM for Early Stage Breast Cancer
NCT05894239 A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer
NCT04234386 GammaPod Dose Escalation Radiation for Early Stage Breast Cancer
NCT05256225 Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma
NCT03129139 A Phase 1, Multi-Center, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Minnelide™ Capsules Given Alone or in Combination With Protein-Bound Paclitaxel in Patients With Advanced Solid Tumors
NCT05900986 LS301-IT in Partial Mastectomy and Sentinel Lymph Node Biopsy (SLNB) for DCIS or Stage I-II Primary Invasive Breast Cancer
NCT05768139 First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
NCT03678025 Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer
NCT05455658 STEMVAC in Patients With Early Stage Triple Negative Breast Cancer
NCT06542835 Community Partnership for Telehealth Solutions to Counter Misinformation and Achieve Equity
NCT04331535 The Genomic Medicine at VA Study
NCT06162663 Double-blind Randomized Controlled Trial Comparing Suvorexant 20 mg to Placebo for Treatment of Insomnia in Cancer Survivors
NCT04887935 Neoadjuvant SGLT2 Inhibition in High-Risk Localized Prostate Cancer
NCT04799535 Quantitative Microvasculature Imaging for Breast Cancer Detection and Monitoring
NCT06617858 Trial of AMB-05X for Patients With ctDNA(+) Colorectal Cancer After Curative-intent Treatment
NCT03382158 International PPB/DICER1 Registry
NCT03526835 A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
NCT05524935 Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma
NCT06192758 Dose Escalation Study Evaluating Safety of TheraSphere Prostate Cancer (PCa) Device
NCT05304858 Tumor Microenvironment Analysis of Prostate Cancer Metastasis
NCT06441474 Understanding and Addressing Rejection of Personalized Breast Cancer Risk Information in Women
NCT05902520 Adoptive Cell Therapy Using Cancer Specific CD8+ Tumor Infiltrating Lymphocytes in Adult Patients With Solid Tumors
NCT06625320 Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)
NCT02749474 Maternal Cancer Diagnosis and Treatment During Pregnancy:a Database for Maternal, Fetal, and Neonatal Outcomes
NCT04567420 DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)
NCT05111574 Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery
NCT04471974 ZEN-3694, Enzalutamide, and Pembrolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer
NCT06217874 Collection of Specimens and Clinical Data for Patients With Recurrent or Metastatic Breast Cancer or Male Breast Cancer
NCT06393374 Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
NCT05458674 Tucatinib+Trastuzumab+Eribulin in HER2+ MBC
NCT05585320 A Phase 1/2a Study of IMM-1-104 in Participants With Previously Treated, RAS-Mutant, Advanced or Metastatic Solid Tumors
NCT02743858 Lymphedema Surveillance Study
NCT06797635 Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)
NCT06132958 Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post Immunotherapy Endometrial Cancer (MK-2870-005)
NCT05754658 African Cancer Genome: GMD
NCT04585958 Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer
NCT04998682 Prospective Evaluation of Targeted Axillary Dissection (TAD)
NCT05912231 Ultrahypofractionation and Normal Tissue Toxicity
NCT03161431 SX-682 Treatment in Subjects With Metastatic Melanoma Concurrently Treated With Pembrolizumab
NCT05006131 Pancreatic Cancer Screening for At-risk Individuals
NCT05770531 Circulating Tumor DNA to Guide Changes in Standard of Care Chemotherapy
NCT03127631 A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients
NCT05736731 A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants with Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression
NCT05361174 A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer
NCT05983276 Decitabine and Selinexor in Combination to Reverse Drug Resistance With Standard Chemotherapy in Ovarian Cancer
NCT05721976 With Love, Grandma ("Con Cariño, Abuelita") Pilot Study
NCT04394676 The Impact of Low Pressure Pneumo in RARP II
NCT04862663 Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)
NCT05438563 MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Intermediate Grade Prostate Cancer
NCT03454035 Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors
NCT05384535 Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort
NCT06250335 Impact of a Prebiotic Food-enriched Diet (PreFED) in Combination With Ipilimumab/Nivolumab Combination Immune Checkpoint Blockade (ICB) in ICB-refractory Melanoma Patients
NCT03439735 Determinants of Resistance to Endocrine Therapy and a Cyclin-dependent Kinases 4 and 6 (CDK4/6) Inhibitor for HR+ MBC
NCT06691035 Immunologic Targeting of ESR1 Receptor for Hormone Receptor Expressing Metastatic Breast Cancer
NCT02189486 Prostate Cancer Upgrading Reference Set
NCT06788886 Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases
NCT06294886 Vaginal Fluid Collection for Detection of Endometrial Cancer
NCT06557057 Impact of Aromatase Inhibitor Therapy on Glucose Homeostasis and Diabetes Risk
NCT06399757 A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors
NCT06675357 Using FAPI PET/MRI to Evaluate Prostate Cancer
NCT03863457 [18F] F-GLN by PET/CT in Breast Cancer
NCT04561362 Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies
NCT05077280 A Study of Concurrent Stereotactic Body Radiotherapy With Opdualag in Metastatic Uveal Melanoma
NCT06252662 Liposomal Bupivacaine Vs Bupivacaine with Dexmedetomidine in Erector Spinae Plane Blocks for Mastectomies
NCT05642962 Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC)
NCT02000089 The Cancer of the Pancreas Screening-5 CAPS5)Study
NCT04840589 Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors
NCT03567889 Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C Melanoma Patients
NCT06157892 A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors
NCT06245889 PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC
NCT04599140 SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial
NCT06568562 XL092 in Patients With Metastatic Castration-Resistant Prostate Cancer
NCT05932862 A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Patients With Advanced Solid Tumors
NCT00539162 Use of the CA 125 Algorithm for the Early Detection of Ovarian Cancer in Low Risk Women
NCT06447662 A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.
NCT06173362 Abiraterone and Prednisone or Darolutamide for the Treatment of Advanced Prostate Cancer
NCT05304962 FIH Study of RGT-419B Alone and With Endocrine Therapy in HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer
NCT05313191 Prospective Evaluation of Pencil Beam Scanning Proton Therapy for Previously Irradiated Tumors
NCT05654246 Susan G. Komen's ShareForCures
NCT05155046 18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy
NCT06882746 A Study to Test Different Doses of BI 765049 in People With Advanced Cancer of the Colon, Rectum, Stomach, or Pancreas
NCT06907446 Comparison of New SUREcore Biopsy of Needle to Standard of Care During Transperineal Prostate Biopsies
NCT05049746 Identifying Decision Making Needs for Older Adult Women with Stage I-III Breast Cancer Considering Neoadjuvant or Adjuvant Chemotherapy
NCT06518746 Gonadal Dysgenesis Tissue Cryopreservation for Fertility Preservation
NCT06378346 GU-01: Glycyrrhizin in Prostate Cancer
NCT06503146 18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection
NCT06079346 A Study of OT-101 With mFOLFIRINOX in Patients With Advanced and Unresectable or Metastatic Pancreatic Cancer
NCT05094804 A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents
NCT05396872 Patient Decision-making About Precision Oncology in Veterans With Advanced Prostate Cancer
NCT04588662 A Prospective Natural History Study in Uveal Melanoma
NCT06767462 An Ophthalmic Safety Study in Patients With Breast Cancer
NCT03065062 Study of the CDK4/6 Inhibitor Palbociclib (PD-0332991) in Combination With the PI3K/mTOR Inhibitor Gedatolisib (PF-05212384) for Patients With Advanced Squamous Cell Lung, Pancreatic, Head & Neck and Other Solid Tumors
NCT06070012 Tebentafusp in HLA-A*0201 Positive Previously Untreated Metastatic Uveal Melanoma
NCT06671912 Testing Low Dose Tamoxifen for Invasive Breast Cancer, the (LoTam) Trial
NCT04754412 Culturally Based Brief Expressive Writing Intervention for the Improvement of Health in Chinese Immigrant Stage 0-III Breast Cancer Survivors, Writing to Heal Study
NCT05839912 Excision of Lymph Node Trial (EXCILYNT) (Mel69)
NCT05479812 Dose Escalation and Expansion Study of WTX-124 As Monotherapy and in Combination with Pembrolizumab (pembro) in Patients with Selected Advanced or Metastatic Solid Tumors
NCT03832855 Assessing the Immunogenicity of pING-hHER3FL
NCT06136650 A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
NCT06400550 Identification of Metabolic Phenotypes Associated With Melanoma Metastasis
NCT06054555 A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma
NCT06461650 Preoperative Nicotine Cessation for Women With Breast Cancer Recommended for Reconstruction
NCT05754580 High-dose Brachytherapy Boost With Stereostatic Body Radiation Therapy to Intermediate or Higher Risk Prostate Cancer
NCT04684862 Infusion System for Hepatic Cancer
NCT03991962 Phase II Study to Evaluate Modified Folfirinox and Stereotactic Body Radiation Therapy in Non-metastatic Unresectable Pancreatic Adenocarcinoma
NCT06369246 PRORAD-5 PROstate RADiation in 5 Fractions: Phase Ib Five Fraction Radiotherapy for Patients With Advanced Prostate Cancer
NCT05629546 Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint Inhibitors
NCT03709446 Leflunomide in Previously Treated Metastatic Triple Negative Cancers
NCT05534646 Study of Apalutamide with Carotuximab in Metastatic, Castration-Resistant Prostate Cancer
NCT04989946 Androgen Deprivation, With or Without pTVG-AR, and With or Without T-Cell Checkpoint Blockade, in Patients With Newly Diagnosed, High-Risk Prostate Cancer
NCT03821935 Study to Determine the Safety, Tolerability, Pharmacokinetics and Recommended Phase 2 Dose (RP2D) of Livmoniplimab (ABBV-151) as a Single Agent and in Combination With Budigalimab (ABBV-181) in Participants With Locally Advanced or Metastatic Solid Tumors
NCT06756035 CT-95 in Advanced Cancers Associated with Mesothelin Expression
NCT06238986 Relationship Between Alterations in the GI Microbiome and GI Inflammation on Symptom Burden in Women with Breast Cancer Receiving Chemotherapy
NCT06037863 Evaluation of the Impact of Empty Versus Full Bladder in Patients with Prostate Cancer, RELIEF Trial
NCT05225363 Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian Cancer
NCT04927663 11C-YJH08 PET Imaging for Detection of Glucocorticoid Receptor Expression
NCT04575935 Minimally Invasive Surgery After Neoadjuvant Chemotherapy for the Treatment of Stage IIIC-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer, LANCE Trial
NCT04706663 Precision-Based Genomics in Prostate Cancer
NCT05918263 Exercise for Tumor Suppressive Impact in Black Men With Prostate Cancer on Active Surveillance: The REMOVE Trial
NCT05850663 Quality of Life Assessment of Radiotherapy in Recurrent Head and Neck Cancer
NCT06423963 Remote Exercise and Nutritional Prehabilitation for Pancreatic Cancer
NCT05998135 Repurposing Atovaquone for the Treatment of Platinum-Resistant Ovarian Cancer
NCT06820463 A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer
NCT05428735 The DRAGON 2 Trial
NCT02896335 Palbociclib and Pembrolizumab in Central Nervous System Metastases
NCT05463796 InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
NCT04568616 Phase II Study of Neoadjuvant ArOMatase Inhibitor Therapy for ER+ Breast Cancer (NAOMI)
NCT06314958 Stage II/III Colorectal Cancer Recurrence
NCT05377996 A Study of XMT-1660 in Participants With Solid Tumors
NCT06551116 QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer
NCT06703996 InBody Band 3 Fitness Tracker to Improve Health Outcomes and Quality of Life in Black Prostate Cancer Survivors
NCT05036096 Cone Beam Breast CT for Breast Cancer Screening
NCT05838716 High-Dose Vitamin D Supplementation for ADT-Induced Bone Loss in Older Prostate Cancer Patients
NCT06584396 Evaluating Mechanical Properties of Post-Mastectomy Skin Flaps to Estimate Reconstruction Risks, the EMPOWER Study
NCT04997096 Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy
NCT04130516 Study Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and with Pembrolizumab
NCT06246916 A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma
NCT06428396 Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)
NCT04251416 A Study of Sacituzumab Govitecan (IMMU-132) in Endometrial Carcinoma
NCT03819296 Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer
NCT00034216 Collection of Blood From Patients With Cancer
NCT06326216 Determination of Baseline Levels for Prostate Cancer-Derived Extracellular Vesicles Following Local Treatment of Prostate Cancer
NCT02611024 Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors
NCT06466434 Prebiotic Food-enriched Diet (PreFED) to Enhance the Microbiome and Response to First-line Immunotherapy in Unresectable Melanoma
NCT04981834 Robot-Assisted Radical Prostatectomy With or Without Vesicopexy in Patients With Prostate Cancer
NCT04305834 Abemaciclib and Endocrine Therapy in Older Patients with Breast Cancer.
NCT05514717 A Study of XMT-2056 in Advanced/Recurrent Solid Tumors That Express HER2
NCT06639724 Perioperative Fostamatinib With Gemcitabine and Nab-paclitaxel in Resectable Pancreatic Cancer
NCT02290834 Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast Cancer
NCT04961996 A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
NCT06364696 A Study to Find a Suitable Dose of ASP4396 in Adults With Solid Tumors
NCT06566716 A Diagnostic Test to Evaluate Cancer Risk Before Surgery in Women with an Ovarian Mass
NCT05692596 The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics
NCT04022616 Myeloid-Derived Suppressor Cell Function in Breast Cancer Patients
NCT05946824 This Study is Evaluating a New Radiation Treatment Technique for Patients Who Have Had Prostate Cancer, Undergone Surgery for Cancer, and Then Have Evidence That Their Prostate Cancer Has Returned.
NCT06704724 A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene
NCT05268224 A Tear-based, Lab-developed Test for Breast Cancer for Women With Dense Breast Tissue
NCT05297734 Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer
NCT04898634 A Study of JNJ-78278343, a T-Cell-Redirecting Agent Targeting Human Kallikrein 2 (KLK2), for Advanced Prostate Cancer
NCT06219434 Evaluation of a Mindfulness Intervention to Prevent Chemo-brain in Women Preparing for Chemotherapy for Breast Cancer
NCT06298734 High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial
NCT06011434 Testing Conversation Aid in Practice
NCT03540017 HIPEC After Initial CRS in Patients Who Have Received NACT
NCT05356117 Resistance Exercise Combined With Protein Supplementation in People With Pancreatic Cancer: The RE-BUILD Trial
NCT05305924 Fulvestrant+Abemaciclib With Run-In of Fulvestrant in Er-Positive, Her2-Negative Metastatic Breast Cancer
NCT05751434 A Study on the Effects of Exercise Therapy on Signs of Prostate Cancer
NCT03492424 Ablative Therapy in the Management of Prostate Cancer
NCT05692024 COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER
NCT03965234 Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases
NCT03784924 EDRN Prostate MRI Biomarker Study
NCT05170334 Binimetinib Plus Belinostat for Subjects With Metastatic Uveal Melanoma
NCT05812924 A Novel Therapy for Breast Cancer Survivors With Genitourinary Syndrome of Menopause
NCT04267796 Lifestyle Intervention for the Reduction of Breast Cancer Risk in Normal Weight Women
NCT05125016 A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With Cemiplimab or REGN5678 for Adult Participants With Advanced Prostate Cancer
NCT03354416 Profiling of Radiological Factors in Treatment and Outcomes in Prostate Cancer
NCT05981716 Young Breast Cancer Survivors Study
NCT05830058 Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma
NCT06492616 A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
NCT02830724 Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers
NCT04858334 APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
NCT05054296 Modifying Metabolic Syndrome and Cardiovascular Risk for Prostate Cancer Patients on ADT Using a Risk Factor Modification Program and Continuous Fitbit Monitoring
NCT05930496 Evaluating the Effects of an Exercise Intervention on the Gut Microbiota in Stage II-III Colorectal Cancer Survivors
NCT05548296 A Study of ACR-368 in Ovarian Carcinoma, Endometrial Adenocarcinoma, and Urothelial Carcinoma
NCT05864196 Two Fraction Prostate SBRT With DIL SIB
NCT06623396 A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer
NCT03990896 Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial
NCT06555796 Evaluation of Xaluritamig in High-Risk, Biochemically Recurrent, Non-metastatic Castrate-sensitive Prostate Cancer
NCT06090916 Malnutrition Screening and Dietary Intervention to Improve Nutrition Outcomes in Patients With Unresectable Pancreatic Cancer
NCT06122896 Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals
NCT05384496 Axitinib and Nivolumab for the Treatment of Mucosal Melanoma
NCT04789486 Nano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic Cancer
NCT04792463 Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome
NCT04914663 All-extremity Exercise During Breast Cancer Chemotherapy
NCT06389786 Accuracy of 18F-rhPSMA-7.3 PET/ MRI for Prediction of Lymph Node Metastasis in Localized High-Risk Prostate Cancer
NCT05652686 A Study of Peluntamig (PT217) in Patients with Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)
NCT04158635 Gemcitabine, Nab-Paclitaxel, and Bosentan for the Treatment of Unresectable Pancreatic Cancer
NCT06774963 A Phase 1 Study of LNCB74 in Advanced Solid Tumors
NCT02476786 Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score
NCT05496686 Targeted Alpha Particle Radiotherapy for Metastatic Uveal Melanoma
NCT03420963 Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors
NCT05840263 Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer
NCT06014086 Intratumoral PH-762 for Cutaneous Carcinoma
NCT05628363 Adaptive Stereotactic Body Radiation Therapy to the Prostate and Pelvic Nodes With Simultaneous Integrated Boost to the MR-detected Nodule for Patients With High-risk and Unfavorable Intermediate-risk Prostate Cancer
NCT04711824 Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases
NCT05565417 Study of the Monoclonal Antibody IMT-009 in Patients with Advanced Solid Tumors or Lymphomas
NCT06410534 A Phase II Study Evaluating an Organ Preservation Strategy Using Immune Checkpoint Blockade for Participants With Primary Colorectal or Gastroesophageal Cancer
NCT05321134 Evaluation of SINGLE PORT (SP) Robotic Technology in Colorectal Surgery
NCT03772834 Methylphenidate and Exercise in Reducing Cancer-Related Fatigue in Patients with Prostate Cancer
NCT04119024 Gene Modified Immune Cells (IL13Ralpha2 CAR T Cells) After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors
NCT05607017 Losartan in Prevention of Radiation-Induced Heart Failure
NCT05776524 Study of Amplitude-Modulated Radiofrequency Electromagnetic Fields in Metastatic Pancreatic Cancer
NCT05497024 Older Men's Decision Making About Active Surveillance for Prostate Cancer - Aim 3: Decision Aid Cognitive and Usability Testing
NCT05565534 Diabetes Care for Breast Cancer Patients
NCT06391034 Magnetic Resonance (MR) Imaging With Hyperpolarized 13C-Pyruvate +/- 13C,15N-Urea in Patients With Prostate Cancer
NCT05743517 Physical Activity Intervention Among Older Women With Gynecologic Cancers (Fit4Treatment)
NCT06274034 MUSE-S Headband System for Improving Anxiety and Insomnia Among Breast Cancer Survivors
NCT06625034 Radiation Therapy With RapidPlan Knowledge-based Planning vs Human-Driven Planning for Treatment of Prostate Cancer
NCT03646617 Ipilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic Melanoma
NCT06193486 Autologous Gamma Delta T Cells to Target Prostate Stem Cell Antigen in mCRPC
NCT06299163 NM32-2668 in Adult Patients with Selected Advanced Solid Tumors
NCT06287463 Study of DCC-3084 in Participants With Advanced Malignancies Driven by the Mitogen-Activated Protein Kinase (MAPK) Pathway
NCT05226663 A Radiotracer ([18F]FluorThanatrace) by PET/CT for the Imaging of Breast Cancer
NCT04074135 Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors
NCT05574686 Telemonitoring Hypertension and Breast Cancer
NCT06400563 MRg-NIRS Imaging System Breast Cancer Trial
NCT06421935 M9466 Alone or in Combination in Advanced Solid Tumors (DDriver 501)
NCT04969835 A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours
NCT06778863 A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
NCT04115163 Biologically Optimized Infusion Schedule of Gemcitabine and Nab-Paclitaxel for the Treatment of Metastatic Pancreatic Cancer
NCT06100263 Breast Cancer Resiliency Through Exercise Program (B-REP)
NCT06662435 GYNecologic Cancer-Related COGnitive Impairment
NCT04751435 Developing New Educational Materials About Genetic Testing for a Diverse Group of Cancer Patients
NCT04188535 Serial MRI Scans During Radiation Therapy
NCT05610735 Combination Therapy for Recurrent Ovarian Cancer
NCT06500858 MBC Physical Activity Study
NCT05787834 Home-based Respiratory Muscle Training for Minimizing Side Effects in Patients Undergoing Treatment for Breast Cancer
NCT06291324 WATD and Cancer-Related Fatigue: A Study For Patients Undergoing Anti-Cancer Treatment
NCT05468034 Exercise in Metastatic Breast Cancer: EMBody
NCT04825834 DNA Evaluation of Fragments for Early Interception - Lung Cancer Training Study (DELFI-L101 Study)
NCT05748834 Study of Tucatinib and Doxil in Participants with Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer
NCT06582017 Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma
NCT06075524 Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types
NCT04646434 Brain and Pelvic Floor Muscle Activity of Patients Who Had or Are Undergoing Robot-Assisted Radical Prostatectomy
NCT06011824 A Study of Effect of Megakaryocytes and Platelets in Breast Cancer
NCT06136624 Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
NCT04677816 Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients
NCT06113016 Prevention of Frailty with Fisetin and Exercise (PROFFi) in Breast Cancer Survivors
NCT05641896 Study of [18F]FAPI-74 PET in Patients with Gastrointestinal Cancers
NCT05576896 Hydroxychloroquine in Combination With Encorafenib and Cetuximab or Panitumumab in the Treatment of Metastatic BRAF-mutated Colorectal Cancer Refractory
NCT06798558 Neoadjuvant Lu-177-PSMA-617 in Patients With High Risk Localized Prostate Cancer Undergoing Radical Prostatectomy
NCT04715958 Prediction of Neoadjuvant Chemotherapy Response Using Contrast-Enhanced Ultrasound in Patients With Locally Advanced Breast Cancer
NCT00291096 High Risk Breast Clinic: Protocol for Women at Increased Risk for Developing Breast Cancer
NCT06315296 An Interactive Time-Restricted Diet Intervention (txt4fasting) for Reducing Neurocognitive Decline and Improving Survival in Patients With Brain Metastases From Breast or Lung Cancer
NCT04457596 T-DM1 and Tucatinib Compared with T-DM1 Alone in Preventing Relapses in People with High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial
NCT04751396 Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
NCT05142358 A Prospective Study to Evaluate Continuous Positive Airway Pressure Devices to Reduce Pulmonary Dose
NCT06247995 A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.
NCT05739981 Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer
NCT06084481 Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400
NCT05999812 Clinical Trial of All-trans-retinoic Acid, Bevacizumab and Atezolizumab in Colorectal Cancer
NCT06494046 Defining Musical Toxicity and Its Effect on Patient Well-being
NCT06027268 Phase II Trial of Trilaciclib, Pembrolizumab, Gemcitabine and Carboplatin in Metastatic Triple-Negative Breast Cancer
NCT04606446 Study of PF-07248144 in Advanced or Metastatic Solid Tumors
NCT05469269 Cleveland African American Prostate Cancer Project
NCT02977468 Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancer
NCT04365569 Evaluating the Effectiveness of an Individualized Nutrition and Physical Activity Counseling Program
NCT05755269 Adding a Genetic Risk Evaluation to Standard Breast Cancer Risk Assessment for African American and Hispanic Women
NCT04739072 Minimal Residual Disease Assessment in Patients with Colorectal Cancer, the MiRDA-C Study
NCT06347068 Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells
NCT06444269 Precision Medicine in Action: Phase II Trial of Response Adaptive Ablative Pre-operative SPBI (RAPS) and Non-operative Sentinel Lymph Node Biopsy in Patients With Early-stage ER+ Breast Cancer: RAPS Trial
NCT04905069 Effectiveness of the SpaceOAR Vue System in Subjects With Prostate Cancer Being Treated With Stereotactic Body Radiotherapy
NCT06844669 HER2HEART-US: Prevention of Cardiotoxicity in Breast Cancer Patients Receiving HER2-directed Therapy
NCT04891068 BRE-04: Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast Cancer
NCT06099769 A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer
NCT02332668 A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)
NCT06833268 Real-world Outcomes of Patients With HER2+ Metastatic Breast Cancer After Treatment With Trastuzumab Deruxtecan
NCT03228667 QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors
NCT04994067 Intra-Operative Radiation Registry
NCT05155501 Clinical Trial of Approaches to Prostate Cancer Surgery
NCT06710067 Urine Metabolites in the Diagnosis of Disease
NCT04783467 Time Restricted Eating (TRE) Among Endometrial Cancer Patients
NCT05795101 TRUDI: TDXD+Durva in HER2+/low IBC
NCT05464667 Preoperative Irradiation for Stage I Breast Cancer
NCT06239467 First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer
NCT05837767 A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue
NCT06697301 Safety and Efficacy of EIK1001-006 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.
NCT05736367 Investigating the Metabolic Pathways in Hormone Receptor Positive/HER2 Negative Breast Cancer
NCT05554367 Palbociclib and Binimetinib in RAS-Mutant Cancers, A ComboMATCH Treatment Trial
NCT05355701 A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.
NCT06521567 A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer
NCT05130801 A Study of Multiparametric MRI and pHLIP® ICG in Breast Cancer Imaging During Surgery
NCT06824467 A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
NCT04349501 Biomarker Monitoring of Prostate Cancer Patients With RSI MRI (ProsRSI)
NCT04674267 Resilience and Equity in Aging, Cancer, and Health (REACH)
NCT04703244 Development of Patient Derived Xenografts (PDX) in Patients With Breast Cancer
NCT05819892 Phase I Trial Testing the Safety and Tolerability of Chemoradiation Followed by Chemotherapy + Dostarlimab for Stage IIIC, Node Positive, Endometrial Cancer
NCT05376592 Assoc. of Genomic Polymorphisms With Cancer Cachexia in Subjects With Panc Adenocarcinoma
NCT05705492 Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer
NCT05498792 Study of CBL0137 in Combination With Ipilimumab and Nivolumab Therapy in Melanoma
NCT06346067 A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)
NCT04631744 Cabozantinib in Patients With Metastatic Castrate Resistant Prostate Cancer (mCRPC)
NCT02870244 Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes
NCT04512144 Mindfulness in Endometrial and Cervical Cancer
NCT04787744 Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer
NCT06568692 A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer
NCT01954992 Glufosfamide Versus 5-FU in Second Line Metastatic Pancreatic Cancer
NCT06229392 A Study to Evaluate the Intratumoral Influenza Vaccine Administration in Patients With Breast Cancer
NCT05912244 A Study of IO102/IO103, Nivolumab, and Relatlimab in People With Melanoma
NCT05864144 A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors
NCT04106492 Phase 1/2a Study of SQ3370 in Patients With Advanced Solid Tumors
NCT05472792 Adjuvant Monotherapy With Endocrine Therapy or Accelerated Partial Breast Irradiation Following Lumpectomy for Low Risk Breast Cancer Patients Over 65 (CAMERAN)
NCT06533644 A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer
NCT05345444 Radiation Therapy and IRreversible Electroporation for Intermediate Risk Prostate Cancer (RTIRE)
NCT04009044 Topical Afimoxifene in Treating Patients With Breast Cancer Who Have Undergone Radiation Therapy on One Breast
NCT05056844 Contrast Enhanced Spectral Mammography for the Evaluation of Pathologic Nipple Discharge
NCT06733350 Testosterone Replacement Therapy for the Treatment of Low Testosterone in Hypogonadal Men With Localized Prostate Cancer on Active Surveillance
NCT06730750 A Study of BMS-986490 With or Without Bevacizumab in Advanced Solid Tumors
NCT05248581 Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases
NCT05691010 A Study of Short-Course Radiation Therapy With Chemotherapy in People With Endometrial Cancer
NCT06572410 Prospective Analysis of EnVisio Spatial Intelligence for Soft Tissue Localization and Guided Surgical Excision
NCT06111781 The SUGAR Study; SBRT and Relugolix) for Prostate Cancer
NCT06658912 Planning Grant for TOPS for African American Breast Cancer Survivors
NCT06305312 Community Services Navigation to Advance Health Equity in Breast Cancer Screening
NCT06612281 Evaluation of Gixam's Performance in a FIT Negative Population
NCT06173310 DCE-MRI Guided Neoadjuvant Chemotherapy for Borderline Resectable Pancreatic Cancer
NCT06749210 DAANCE for CHEMOTHERAPY-INDUCED NEUROPATHY
NCT02040610 Hypofractionated Image Guided Proton Therapy for Low andIntermediate Risk Prostate Cancer
NCT04877912 Accurate, Rapid and Inexpensive MRI Protocol for Breast Cancer Screening
NCT05269381 Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
NCT06516510 A Dosimetry Study of Lutetium (177Lu) rhPSMA-10.1 and Lutetium (177Lu) Vipivotide Tetraxetan (Pluvicto®) in Patients With Non-curative Metastatic Prostate Cancer
NCT05435495 Mechanisms of Resistance to PSMA Radioligand Therapy
NCT05138510 Sexual Health in Breast Cancer Patients
NCT05979610 Using Reiki Therapy to Improve Symptoms Associated With Brachytherapy in Patients With Gynecological Malignancies
NCT05705401 Testing Radiation and HER2-targeted Therapy Versus HER2-targeted Therapy Alone for Low-risk HER2-positive Breast Cancer
NCT04474301 Well-Being and Health-Related Quality of Life in Melanoma Patients During COVID-19 Pandemic
NCT05417867 Evaluating the Association Between Changes in the Gut Microbiome, Fatigue, and Chemotherapy-Induced Nausea in Early Stage Breast Cancer
NCT05039801 IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors
NCT05964504 Improving Survival for Metastatic Lobular Breast Cancer (PLUMB Registry)
NCT05581004 A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors
NCT05112601 Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma
NCT04104672 A Study to Evaluate the Safety and Tolerability of AB680 in Participants With Gastrointestinal Malignancies
NCT01950572 Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma
NCT05907304 A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations
NCT05501704 ETHAN - ET for Male BC
NCT05751668 Finding an Effective Dose of GM1 to Reduce or Prevent Neuropathy (Numbness or Weakness) Due to Treatment With Paclitaxel (Phase II)
NCT05838768 Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.
NCT05797168 Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors
NCT06246968 A Study of Pembrolizumab and Cryoablation in People with Breast Cancer
NCT06215469 Portable Scalp Cooling System (PSCS) to Prevent Hair Loss for Breast Cancer Patients (Cooler Heads)
NCT06228768 Acupressure for Aromatase Inhibitor-Associated Musculoskeletal Symptoms in Patients With Breast Cancer
NCT05396846 My Best GI Eating Study
NCT06340646 Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)
NCT01365169 Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"
NCT05789069 A Study of HFB200603 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors
NCT03611868 A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors
NCT06678269 A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer
NCT06171269 Using MRI to Identify Areas to Receive Lower Doses of Radiation Treatment in Men With Prostate Cancerdose Mapping to Preserve Quality of Life
NCT06465069 A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
NCT06103669 Locally AblatiVe TherApy in OLigO-pRogressive SOlid TUmorS (VALOROUS)
NCT06067269 Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients with Prostate Cancer, HEATWAVE Trial
NCT01102569 Pancreatic Cancer Genetics
NCT05113368 Regorafenib Combined With Fulvestrant in Recurrent Low-Grade Serous Ovarian Cancer
NCT03460769 Evaluation of a Mixed Meal Test for Diagnosis and Characterization and Type 3c Diabetes Mellitus Secondary to Pancreatic Cancer and Chronic Pancreatitis (DETECT)
NCT05929768 Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
NCT04611568 War on Melanoma™ Public Health & Education Campaign
NCT03050268 Familial Investigations of Childhood Cancer Predisposition
NCT06129604 Pilot Window of Opportunity Trial (POET)
NCT06342401 Early Onset Colorectal Cancer Detection
NCT04854304 Abbreviate or FAST Breast MRI for Supplemental Breast Cancer Screening for Black Women at Average Risk and Dense Breasts
NCT02279004 A Prospective Study of Plasma Genotyping as a Noninvasive Biomarker for Genotype-directed Cancer Care
NCT04868604 64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE)
NCT05727904 Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.
NCT06745804 Study of 68Ga-R10602
NCT02021604 Fluorodopa F 18 in Congenital Hyperinsulinism and Insulinoma
NCT04314401 National Cancer Institute "Cancer Moonshot Biobank"
NCT05535192 TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients
NCT06562192 Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
NCT03919292 Neratinib + Valproate in Advanced Solid Tumors, w/Expansion Cohort in Ras-Mutated Ca
NCT05458544 [Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application
NCT06764940 A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients with Brain Metastases
NCT05726292 A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer
NCT05218044 Cryoablation as a Minimally Invasive Alternative to Surgery for Managing Ductal Carcinoma In Situ
NCT06083844 Phase II Investigation of Pembrolizumab in Combination With Bevacizumab and Oral Cyclophosphamide in Patients With High Grade Ovarian Cancer and Surgically Documented Minimal Residual Disease After Frontline Therapy
NCT03671044 A Study to Evaluate the Efficacy and Safety of Nanosomal Docetaxel Lipid Suspension in Triple Negative Breast Cancer Patients
NCT05607004 (Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer
NCT01834001 Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy
NCT05046301 Contrast-Enhanced Mammography for the Evaluation of Mammographic Microcalcifications
NCT02772367 Generation of Heart Muscle Cells From Blood or Skin Cells of Breast Cancer Patients
NCT06388967 Pancreatic Cancer Detection Consortium
NCT06643767 Evaluation of the Bexa Breast Examination
NCT05023967 Metformin and Nightly Fasting in Women With Early Breast Cancer
NCT03606967 Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer
NCT05684367 Exercise to ReGain Stamina and Energy (The EXERGISE Study)
NCT04580667 Prospective Observational Exploratory Clinical Study to Determine the Assay Cut-Off for the RadTox Test in Prostate Cancer Patients to Predict Gastrointestinal Radiation Toxicity Using Circulating Cell Free DNA Directly From Plasma
NCT06538389 High Cannabidiol Plant Extract (BRC-001) to Improve Aromatase Inhibitor-Induced Arthralgia in Women With Breast Cancer
NCT06092892 IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients with Breast Cancer with Nodal Metastases
NCT06392789 A Conversational Agent (Cecebot) to Improve Insomnia in Stage I-III Breast Cancer Survivors
NCT05946213 Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
NCT04997018 A Study of MRI-guided High-dose Radiation Therapy in Prostate Cancer
NCT06303713 LuCarbo - a Study of 177Lu-PSMA-617 Plus Carboplatin in Metastatic Castrate-resistant Prostate Cancer
NCT06084013 Use of Indocyanine Green in Pancreas Surgery
NCT02610413 Whole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Hypertension Receiving Bevacizumab for Breast Cancer
NCT05879913 ASCVD Management Using CCTA in Prostate Cancer Patients on ADT
NCT05054413 Formulating Expert Consensus Guidelines in Cancer Care Using the Delphi Method
NCT01961713 Circulating Tumor Cell Analysis in Patients With Localized Prostate Cancer Undergoing Prostatectomy
NCT06800313 A Study of HLD-0915 in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)
NCT06060613 Safety and Efficacy of OBX-115 in Advanced Solid Tumors
NCT04222413 Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors
NCT05804318 Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer
NCT04796818 An Investigational Scan (Intravoxel Incoherent Motion Diffusion Weighted Imaging) for the Evaluation of Colorectal Cancer Liver Metastases Treatment Response
NCT05624918 A Study of NovoTTF-200T(P) in Combination With Gemcitabine and Nab-Paclitaxel for Resectable Pancreatic Adenocarcinoma
NCT04038619 Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients
NCT04340141 Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable Pancreatic Cancer
NCT06117241 Reducing Metabolic Dysregulation in Dyads
NCT06599619 Effects of Anti-PD1 Adjuvant Checkpoint Blockade Immunotherapy on Atypical/Dysplastic Nevi
NCT05455619 Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Women With a PI3K Alteration and HR+/Her2- Breast Cancer
NCT05411718 A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome
NCT05683418 A Study to Evaluate the Safety and Tolerability of TOS-358 in Adults with Select Solid Tumors
NCT05637216 Losartan to Reduce Radiation Induced Fibrosis in Breast Cancer Patients
NCT05914116 A Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
NCT04647916 Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases
NCT05462496 Modulation of the Gut Microbiome With Pembrolizumab Following Chemotherapy in Resectable Pancreatic Cancer
NCT06084416 A Study of Sovilnesib in Subjects with Ovarian Cancer
NCT06205316 SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate Adenocarcinoma
NCT04794816 What Women Want: Real Time Results During Screening Mammography in the Era of Patient-Experience Driven Care
NCT03467516 Adoptive Transfer of Tumor Infiltrating Lymphocytes for Metastatic Uveal Melanoma
NCT05980416 Study of EO-3021 in Adult Patients With Solid Tumors Likely to Express CLDN18.2
NCT06551324 A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).
NCT04513717 Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial
NCT06379217 NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.
NCT05415917 Adjuvant Gemcitabine and Capecitabine Chemotherapy in Resected Pancreatic Cancer Following Neoadjuvant Chemotherapy
NCT06150417 MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)
NCT06610617 Neuromodulation of Central Sensory Integration to Improve Postural Control
NCT05838417 Promoting Informed Choice for Breast Cancer Screening: a Longitudinal Study
NCT05997017 Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer
NCT04975217 Fecal Microbial Transplants for the Treatment of Pancreatic Cancer
NCT04548817 Neurocutaneous Melanocytosis Registry
NCT06736717 Onvansertib in Combination With NALIRIFOX for First Line Treatment of Advanced Pancreatic Cancer
NCT04318717 Pembrolizumab and Hypofractionated Radiation Therapy for the Treatment of Mucosal Melanoma
NCT05989724 A First-in-Human Study of SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors
NCT05716516 STUDY02001740;22SCH740: Estradiol For ER+ Advanced Breast Cancer (ESTHER)
NCT05232916 Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
NCT05590624 Metabolic Impact of Prospective Controlled Mediterranean Type Diets on Prostate Cancer
NCT06312124 A Study of Opportunistic Salpingectomy to Prevent Ovarian Cancer
NCT04830124 Nemvaleukin Alfa Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Cutaneous or Mucosal Melanoma - ARTISTRY-6
NCT06208124 A Study of IMM-6-415 in RAS/RAF Mutant Solid Tumors
NCT05646316 Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer
NCT06461416 A Trial for a Preliminary Estimate of the Effectiveness of a Novel Theoretical Framework
NCT06925724 A Study of Ivonescimab in People With Endometrial and Cervical Cancers
NCT05351424 AVI Didactic Experience for Latinx Patient Treatment Adherence and Non-English Speaker Trial Enrollment Study in Rad Onc
NCT03175224 APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
NCT03686124 ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors
NCT04943536 Bicalutamide Implants (Biolen) With Radiation Therapy in Patients With Localized Prostate Cancer
NCT03474913 Upright MRI for Prostate Cancer Screening
NCT05627219 Extending Prostate Genetic Awareness, Navigation, and Delivery: The EXPAND Network
NCT06663319 A Study of JNJ-89402638 for Metastatic Colorectal Cancer
NCT06388018 Tailoring Therapy in Post-surgical Patients With Low-risk Endometrial Cancer
NCT04692818 3D Ultrasound Breast Imaging
NCT05636618 Targeted Alpha-Particle Therapy for Advanced SSTR2 Positive Neuroendocrine Tumors
NCT06507618 Pre-Operative Window of ET to Inform RT Decisions (POWER II)
NCT01050504 Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer
NCT06605404 Pan-tumor MRD Study
NCT04648904 Study of a Shortened Radiation Therapy Schedule in People With Breast Cancer
NCT06418204 Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
NCT06244004 FDG-PET-Guided Metastasis Directed Radiation Therapy for the Treatment of Metastatic Hormone Sensitive Prostate Cancer, The PRTY Trial
NCT06086704 Study of 18F-FFNP Breast PET/MRI
NCT00899301 Collecting and Storing Tissue Samples From Women With or Without Breast Cancer
NCT05132504 Neoadjuvant Folfirinox Combined With Pembrolizumab Followed by Surgery for Patients With Resectable Pancreatic Cancer
NCT02333604 Cancer Experience Registry (CER) for Cancer Patients and Caregivers
NCT06376604 Fasting Mimicking Diet in Chemotherapy of Gynecologic Malignancies
NCT06394804 A Study of Avutometinib, Defactinib, and Letrozole in People With Low-Grade Serous Ovarian Cancer
NCT04576104 Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer
NCT06388304 THRIVE Study: Positive Affect Training for Endocrine Therapy Medication Adherence
NCT04829604 ARX788 in HER2-positive, Metastatic Breast Cancer Subjects (ACE-Breast-03)
NCT05691504 Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers
NCT05919108 Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers
NCT05417308 Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer
NCT06106308 Study of Onvansertib in Combination with FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants with a KRAS or NRAS Mutation
NCT06476808 A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.
NCT04354246 COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies
NCT06500169 Golf Recreational Exercise for Enhanced Survivorship in Prostate Cancer Survivors
NCT06042569 Dose-Reduced Docetaxel With Cyclophosphamide for the Treatment of Vulnerable Older Women With Stage I-III HER2 Negative Breast Cancer, the DOROTHY Trial
NCT06362369 A Study of Oral 7HP349 (Alintegimod) in Combination with Ipilimumab Followed by Nivolumab Monotherapy
NCT06408168 Phase II Study of REPotrectinib With or Without Fulvestrant in Patients With Hormone Receptor-positive Human Epidermal Growth Factor 2-negative Metastatic Invasive LObular Carcinoma Who Received a Prior Endocrine Therapy in Combination With Cyclin-dependent Kinase 4 and 6 Inhibitor (REPLOT Trial)
NCT05712668 Telemedicine Use in Preoperative Counseling for Endometrial Cancer Survivors
NCT05868668 Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic Pain
NCT06001268 Support Through Remote Observation and Nutrition Guidance Program (STRONG-PCS)
NCT02526368 Pilot Study of (MR) Imaging with Pyruvate (13C) to Detect High Grade Prostate Cancer
NCT04589468 Researching the Effect of Exercise on Cancer
NCT05490472 JAB-2485 Activity in Adult Patients With Advanced Solid Tumors
NCT06817668 Evaluating Tolerability of EPUHRT with Brachytherapy Boost
NCT05546268 Study of Oral MRT-2359 in Selected Cancer Patients
NCT06465368 A Study to Learn About the Study Medicine PF-07220060 Together With Letrozole Compared to Letrozole Alone in Women Post Menopause
NCT04644068 Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies
NCT05892068 A Study of Tucatinib Given Before Surgery to People With HER2+ Cancers That Have Spread to the Brain
NCT06915168 CIPN Decision Aid for the Improvement of Chemotherapy Decision Making in Patients With Breast Cancer
NCT04657068 A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
NCT06182072 ProAgio in Pancreatic Ductal Adenocarcinoma (PDAC)
NCT05649072 Identifying Underserved Individuals inTexas With Hereditary Cancer Risk Using Mobile Mammography Units and Telegenetics.
NCT05334069 Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
NCT06835569 A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
NCT04687969 Multimodal Machine Learning Characterization of Solid Tumors
NCT06698146 Colorectal Metastasis to Liver Extraction with Auxiliary Transplant and Delayed Resection
NCT05220046 Palliadelic Treatment to Reduce Psychological Distress in Persons With Advanced Gastrointestinal Cancers
NCT05058846 Pilot Study of Pancreatic Cancer Screening
NCT04167969 The Use of Nanoparticles to Guide the Surgical Treatment of Prostate Cancer
NCT05703269 Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy
NCT04839614 Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia
NCT04541381 The PhOCus Trial: Implementation of Pharmacogenomic Testing in Oncology Care
NCT03854110 Trial to Evaluate Safety and Tolerability of GP-2250 in Combination With Gemcitabine
NCT02170181 Clinical Registry for Oligometastic Disease, Consolidation Therapy, Debulking Prior to Chemotherapy, or Re-Irradiation
NCT06074510 PYLARIFY® PET/CT or PET/MRI in Men with Favorable Intermediate Risk (FIR) Prostate Cancer
NCT05452681 Piloting Y-AMBIENT: a Quality of Life Intervention for Young African American Breast Cancer Survivors
NCT06536881 Gut Microbiome, Adverse Effects, and Markers Through MEtabolic Reprogramming
NCT05366881 cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
NCT04820179 Atezolizumab + Cabozantinib in Patients W/ Metastatic, Refractory Pancreatic Cancer
NCT06691984 Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With Progressive Metastatic Castration-Resistant Prostate Cancer
NCT05050084 Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial
NCT04986579 Scalp Cooling in MBC
NCT05633979 Phase 1b Study of EZH1/2 Inhibitor Valemetostat in Combination With Trastuzumab Deruxtecan in Subjects With HER2 Low/Ultra-low/Null Metastatic Breast Cancer
NCT05419479 Switch Maintenance in Pancreatic
NCT05675579 A Phase II Study of Neoadjuvant Sacituzumab Govitecan and Pembrolizumab Therapy for Immunochemotherapy-resistant Early-stage Triple-negative Breast Cancer (TNBC)
NCT06783179 Postoperative Outcomes and Patient Satisfaction With Mayo Clinic Florida Care Hotel After Mastectomy and Tissue Expander Placement
NCT05464810 Letrozole with and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negative Breast Cancer
NCT04291612 Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease
NCT05259410 Time Restricted Eating During Chemotherapy for Breast Cancer
NCT06818812 A Study to Evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
NCT01035112 Magnetic Resonance Imaging of Breast Cancer
NCT05245812 Safety and Feasibility of Robotic SP Nipple Sparing Mastectomy
NCT05563272 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors
NCT04265872 Bortezomib Followed by Pembrolizumab and Cisplatin in metTNBC
NCT03270072 The Differential Impact of Proton Beam Irradiation Versus Conventional Radiation on Organs-at-risk in Stage II-III Breast Cancer Patients
NCT06663072 Study to Test the Combination of Fulvestrant With Lu-DOTATATE for Advanced Pancreatic Neuroendocrine Tumors
NCT05924672 Efficacy of Ra-223 in PSMA PET Optimally Selected Patients
NCT05498272 Study of Neoadjuvant PARP Inhibition Followed by Radical Prostatectomy in Patients With Unfavorable Intermediate-Risk or High-Risk Prostate Cancer With Select HRR Gene Alterations