Hereditary Cancer


Relevance: Medium
Most relevant for: People who have or are considering breast implants.
Update: FDA updates reported harmful events linked to breast implants
The FDA has updated reported cases of breast implant-associated cancer and breast implant illness. Included in this update is approval of a questionnaire that asks about quality of life and satisfaction with breast implants. (10/20/20). Note: On October 27, 2021 the FDA announced stronger guidance on breast implant safety.
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Relevance: Medium-Low
Most relevant for: Women who consume dairy or soy
Study: Dairy milk may slightly raise breast cancer risk
Debate continues about whether consuming soy or dairy products increases breast cancer risk. This study looked at a large number of women and found no link between soy and breast cancer risk. The study did find that postmenopausal women who drank dairy milk have a small increase in breast cancer risk. (09/04/20)
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Relevance: High
Most relevant for: Women diagnosed with breast cancer who have a mutation in BRCA1, BRCA2 or TP53
Study: What is the risk for a new breast cancer diagnosis in the other breast for women with a BRCA1, BRCA2 or TP53 mutation?
For women who have been diagnosed with breast cancer, knowing their risk of breast cancer in the other (contralateral) breast can help them make decisions about surgery and screening. This study shows that women with an inherited mutation in BRCA1, BRCA2 or TP53 have an increased risk for contralateral breast cancer. This risk is highest in women with a TP53 mutation. (6/6/20)
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Relevance: High
Most relevant for: Women diagnosed with breast cancer at age 50 or younger
Study: Racial and ethnic differences in genetic testing among young breast cancer survivors
Genetic testing is recommended for most women who are diagnosed with breast cancer at age 50 or younger. In this study of young women with breast cancer, while the rates of genetic testing did not differ, the rates of women testing positive for an inherited mutation associated with breast cancer did vary between racial and ethnic groups. (2/27/20)
Este artículo está disponible en español.
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Relevance: Medium-High
Most relevant for: Young women who use hair dye or straighteners
Study: Do hair dyes or straighteners increase breast cancer risk?
Many women use products to color or straighten their hair. A large U.S. study linked the use of permanent hair dye and straighteners to increased breast cancer risk, particularly among black women. This XRAY reviews the limitations of this study and highlights the need for additional research before accepting these conclusions. (1/29/20)
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Relevance: High
Most relevant for: Young, high risk women
Study: Women who exercise have lower breast cancer risk whether or not they have a family history of breast cancer
The effect of physical activity on breast cancer risk was looked at in a study of over 15,000 women. The results suggest that exercise lowers breast cancer risk regardless of family history of breast cancer or menopausal status. (12/6/19)
Este artículo está disponible en español.
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Relevance: High
Most relevant for: People diagnosed with pancreatic cancer
Update: Genetic causes of hereditary pancreatic cancer: BRCA and beyond
An update on hereditary pancreatic cancer presented at the annual American Society of Clinical Oncology meeting covered genes and lifetime risk. The update emphasized that all pancreatic cancer patients should be offered genetic counseling and testing. Genetic test results may impact treatment, screening for other cancers and risk to family members. (11/26/19)
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Relevance: Medium-High
Most relevant for: People with early-stage breast cancer
Study: A new blood test may help predict early-stage breast cancer patients at highest risk for recurrence
Which patients are at risk for a relapse of early-stage breast cancer? Tests to predict recurrence would help find people who need more monitoring after treatment and provide a chance to find and treat them earlier. This study looked at whether a blood test for tumor DNA (called circulating tumor DNA or ctDNA) is useful for finding people with recurrence earlier than current clinical practice. (11/4/19)
Este artículo está disponible en español.
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Relevance: Medium-Low
Most relevant for: Women diagnosed with Ductal Carcinoma In Situ (DCIS)
Personal Story: A “flu shot” against breast cancer? Not so fast
There have been multiple reports in the media of a Florida woman who had a "shot" to treat her DCIS with a promising outcome. This XRAY reviews the underlying story about this early breast cancer vaccine trial. (10/25/19)
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Relevance: Medium-High
Most relevant for: Women with a family history of breast cancer
Study: Does eating meat affect breast cancer risk?
Eating meat has been suggested to increase breast cancer risk. The recent Sister Study looked at meat type, cooking methods and breast cancer risk in a study of 42,012 women. (9/10/19)
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