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Who Should Consider Testing?

Learn about genes and cancer, signs of hereditary cancer, genetic counseling, types of genetic tests and what results mean for you and your family.

Genetic testing for people with pancreatic cancer

All people diagnosed with pancreatic cancer meet national guidelines for genetic counseling and testing. Studies analyzing the number of pancreatic cancer patients who have an inherited mutation have found that:

  • Up to 20% of patients with pancreatic cancer have inherited mutations in a gene linked to cancer risk.
  • About 3-10 percent of people with pancreatic cancer have a family history of the disease. 
  • Inherited mutations in BRCA1 and BRCA2 are the most common cause of inherited pancreatic cancer. Together, about 6 percent of all pancreatic cancer patients have an inherited mutation in BRCA2 or BRCA1.
  • Almost 14 percent of Ashkenazi Jewish people with pancreatic cancer have a BRCA mutation.

Other gene mutations which may increase the risk for pancreatic cancer include:

Benefits of genetic testing for people with pancreatic cancer include:

Updated 12/31/2019

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