Get notified of page updates
Gene Mutations
Review expert guidelines regarding who should consider genetic testing, how to find a genetics expert and how to move forward with testing.

Stay up to date on research and information

Sign Up for FORCE Newsletters
Glossary on

Genes with inherited mutations linked to breast cancer

Multi-gene panel tests look for inherited mutations in many genes at the same time. These tests may include new or less common genes. Some panels may include additional genes other than those listed below. A genetics expert can make sure that the most appropriate test is ordered based on your personal situation and family medical history. They will also make sure that your test results are interpreted correctly.

Genes linked to breast cancer in women

Mutations in the following  have been linked to increased risk for breast cancer in women.

  •  (especially )
  •  (especially )
  •  (especially )
  •  (especially )
  • (only in people with neurofibromatosis)


Mutations in the following genes may also be linked to increased breast cancer risk. More research is needed to confirm a link to breast cancer and develop risk-management guidelines. 

  •  (especially )
  •  (only in people with a 657del5 mutation)

Genes linked to breast cancer in men

Mutations in the following genes have been linked to breast cancer risk in men.

Last updated January 31, 2022