CDKN2A: Options for Managing Cancer Risk

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• Perform monthly self-exams to look for skin changes. Have a friend or family member help with hard to see areas of the body.
• Watch moles closely for any signs of change in shape, size, or color.
• Twice yearly dermatologist exam should include mole mapping, or full body photography. Doctors may also view moles with a hand-held device known as a dermatoscope. Any suspicious moles or other skin changes should be removed by a doctor so the tissue can be analyzed by a pathologist.
• Practice sun safety and take protective steps when outdoors. Avoid being outside during the peak sun exposure hours between 10:00 AM and 4:00 PM, seek shade when available, use sunscreen frequently, wear a hat with a brim at least 3 inches wide that extends all the way around the head, and wear protective clothing that covers the arms and legs.
• In people that have had melanoma, thorough skin exams by a dermatologist should be done every month depending on several factors, including number of moles, time since diagnosis, skin type and melanoma type.

40 (or 10 years younger than the earliest case of pancreatic cancer in the family)

• Annual screening for pancreatic cancer with MRI/MRCP or EUS.
• Before undergoing screening, people should have a conversation with their doctor about the potential benefits, risks, costs and limitations of screening.
• Pancreatic cancer screening should be performed at hospitals with experience managing patients at high risk for pancreatic cancer.