Other Considerations for People with Inherited CDKN2A Mutations

The risk for cancer in people with an inherited CDKN2A mutation begins at a young age. Parents with a mutation should speak with a genetics expert about the best timing for testing children.

People with an inherited CDKN2A mutation have a 50 percent chance of passing their mutation on to each of their children. There are options using assisted reproduction technology and preimplantation genetic diagnosis for parents to select embryos that are free of inherited CDKN2A mutations.