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CDKN2A Inherited Mutations

Learn about the cancer risks and prevention and treatment options for people with an inherited CDKN2A mutation
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Information for People with an Inherited CDKN2A Mutation

People with an in CDKN2A have increased risk for pancreatic cancer and melanoma. 

Experts have created guidelines which estimate cancer risks and outline recommendations for managing these risks in people with a CDKN2A mutation. 

There may be family planning concerns and options for people with an inherited CDKN2A mutation. 

Each of these topics is outlined in more detail in the sections highlighted below. 

More Information on CDKN2A Mutations

Cancer Risks

Cancer risk estimates are updated based on the latest research. Read about the lifetime risk for different cancers in people with inherited CDKN2A mutations. 

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Risk Management Options

Read about the latest expert guidelines for cancer screening and prevention for people with a CDKN2A mutation. Learn about research studies enrolling high-risk patients.  

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Cancer Treatment Options

Tumor  testing and genetic testing can provide additional clues about which treatments may work best for your cancer. People who test positive for a CDKN2A mutation may have additional treatment or clinical trial options available to them. 

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Other Considerations

Learn additional information about inherited CDKN2A mutations and options related to family planning. 

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More Resources

Participate in Prevention Research

The screening and prevention studies below are enrolling people with CDKN2A mutations. To search for more studies, visit our Search and Enroll Tool