Colorectal Cancer



Relevance: Medium-High
Most relevant for: People with rectal cancer with high mutational burden or mismatch repair problems including people with Lynch syndrome.
Study: Promising early results for people with DNA mismatch repair deficient rectal cancer
A small research study tested the usefulness of the immunotherapy drug dostarlimab for treating locally advanced rectal cancer with a biomarker known as “dMMR” (DNA mismatch repair deficient). None of the participants had evidence of cancer six months later; some remained cancer free for up to 25 months). Many participants had Lynch syndrome. The remarkable response to this treatment may allow people with this particular subtype of rectal cancer to avoid potentially life-changing rectal surgery. (Posted 11/14/22) Este artículo está disponible en español.
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Relevance: Medium-High
Most relevant for: People with Lynch syndrome and people with a personal and/or family history that suggests Lynch syndrome
Study: Resistant starch may help prevent some cancers in people with Lynch syndrome
This study looked at whether a type of nutrient known as resistant starch could lower the risk of cancers in people with Lynch Syndrome. Researchers found that resistant starch can reduce the risk of non-colorectal cancers but not colorectal cancer. (Posted 10/17/22)
Este artículo está disponible en español.
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Relevance: Medium-High
Most relevant for: Cancer patients who are experiencing fatigue related to cancer or its treatment.
Study: Physical activity may decrease fatigue associated with cancer treatment
Many cancer survivors experience fatigue during and after they complete treatment. This study looked at the effect of home-based physical activity on fatigue in cancer survivors. It also looked at whether frequent counseling encouraged people to start and continue their exercise routines. (Posted 8/1/22). Este artículo está disponible en español.
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Relevance: High
Most relevant for: People who are experiencing side effects due to cancer treatment or cancer.
Study: The hidden financial burden of treating cancer care symptoms
Drugs commonly used to treat symptoms of cancer and cancer treatment side effects can cost thousands of dollars out of pocket for patients, depending on what drugs are used. (Posted 6/29/2022). Este artículo está disponible en español.
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Relevance: Medium
Most relevant for: people who take or consider taking melatonin to help with sleep.
Study: Increasing melatonin use raises concerns
Adult use of melatonin as a sleep aid has increased even though its benefits and risks are not well understood. This study looked at trends in melatonin use over the last 19 years. (Posted 4/14/2022)
Este artículo está disponible en español.
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Relevance: Medium-High
Most relevant for: People interested in using cannabis to relieve treatment side effects.
Study: Cannabis use among breast cancer patients
This study looked at patterns of cannabis use among breast cancer patients who are members of online health communities. Almost half of the study participants reported using cannabis to help manage treatment symptoms and side effects. The study also looked at reasons why patients used cannabis, where they obtained it and whether they perceived cannabis to be safe. While this study only looked at cannabis use among breast cancer patients it is likely results would be similar among patients diagnosed with other types of cancers. (posted 1/25/22)
Este artículo está disponible en español.
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Relevance: Medium
Most relevant for: People with multiple sclerosis who are diagnosed with cancer
Study: Multiple sclerosis may affect breast and colorectal cancer survival
People with multiple sclerosis (MS) have lower overall survival after a breast or colorectal cancer diagnosis compared to people diagnosed with these cancers who do not have multiple sclerosis. Survival differed by cancer type. (posted 12/10/21)
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Relevance: High
Most relevant for: people with metastatic or recurrent cancer
Study: Genetic testing for inherited mutations may be helpful for all people with advanced or metastatic cancer
In a study of nearly 12,000 cancer patients with a variety of cancers, eight percent of participants with metastatic cancer had an inherited mutation in a cancer gene that qualified them for a targeted treatment approved by the FDA or for participation in a clinical trial. The majority of people with metastatic cancer were unaware that they had an inherited mutation, and had not receive gene-directed treatment to which their tumor may have responded. The study authors suggest that genetic testing for inherited mutations may be warranted for all patients with advanced or metastatic cancer. (posted 9/30/21)
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Relevance: Medium-Low
Most relevant for: People considering a liquid biopsy to screen for cancer
Update: Blood tests called liquid biopsies for cancer screening, monitoring and treatment
Could a simple blood test change cancer detection, treatment and monitoring? Several companies are offering a type of blood test known as a liquid biopsy to detect multiple cancers at their earliest stages, monitor response to treatment and help choose the best treatment. Although progress has been made using liquid biopsies to treat cancer, these tests have not yet been shown to detect cancer early enough to save lives. (posted 9/29/21)
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Relevance: Medium
Most relevant for: Healthy people with an average colorectal cancer risk
Study: Do sugared beverages increase the risk of early-onset colorectal cancer?
A study of female nurses in the U.S. suggests that a high intake of sugar-sweetened beverages may increase the risk of colorectal cancer before age 50. However, researchers saw few early-onset colorectal cancer cases which limited the findings. (posted 9/21/21)
Este artículo está disponible en español.
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