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Search Results: Prevention, Detection & Risk + Screening & Early Detection (12 results)

1 through 12 of 12
Screening for Pancreatic Cancer in Patients with an Inherited BRCA1, BRCA2, PALB2 or ATM Mutation


Preliminary Evaluation of Screening for Pancreatic Cancer in Patients with an Inherited Genetic Risk Due to a BRCA1, BRCA2, PALB2 or ATM Mutation

Improved screening for pancreatic cancer in high-risk groups, such as people with an inherited BRCA1, BRCA2, ATM, or PALB2 mutation, may help find cancer early and improve survival rates. People enrolled in this study will undergo screening using endoscopic ultrasound or MRI of the abdomen.

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Research Study to Help Improve Family Communication About Inherited BRCA1 or BRCA2 Mutations

Breast, Ovarian, Pancreatic, Prostate

Research Study to Help Improve Family Communication About Inherited Mutations

The Ohio State University and FORCE want to understand if a family communication guide for people with BRCA mutations is helpful and if it’s also useful to have a video that you can text or email to family members that explains your BRCA mutation. We are currently looking for people between the ages of 18-80 who have mutation in BRCA1 or BRCA2, have an active email address, and an internet capable device like a computer, tablet, or smartphone.  Participants will be asked to complete a total of 3 surveys.  Participants will be randomly assigned to either receive just the communication guide or the guide plus the sharable.  Each survey will take 10-15 minutes (the study could take up to 1.5 hours to complete depending on how much time you spend reviewing the study materials). 

You can access the study consent and survey here:

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GENetic Education Risk Assessment and TEsting Study (GENERATE)

The goal of the GENERATE study is to increase the uptake of genetic testing among family members of pancreatic cancer patients who may carry a genetic mutation.

This study involves education about genetic testing, undergoing genetic testing for cancer risk (for those who choose to) and completion of a series of 4 sets of questionnaires.

For more information, visit the study website

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Breast, Ovarian, Prostate, Pancreatic, Melanoma

PHACT Study: Population Health and Cancer Testing

The PHACT study offers genetic testing to women and men of Ashkenazi (Eastern European) Jewish ancestry, age 21 or older. This group is at least ten times more likely than the general population to inherit certain kinds of genetic mutations associated with cancer risk. The study is open to people who live in one of the nine Bay Area counties (Alameda, Contra Costa, Marin, Napa, San Francisco, San Mateo, Santa Clara, Solano, Sonoma).  By participating in the UCSF Population Health and Cancer Testing (PHACT) study you will be provided with a saliva collection kit from Color Genomics, a genetic laboratory. Thirty genes will be analyzed, including BRCA1 and BRCA2, to identify mutations that increase the chance of cancer in both men and women of Ashkenazi (Eastern European) Jewish ancestry and genetic counseling support will be available with every test.  For more information, visit the UCSF Center for BRCA Research. 

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Men at High Genetic Risk for Prostate Cancer


Men at High Genetic Risk for Prostate Cancer

The National Cancer Institute recently opened a clinical trial for prostate cancer screening in men who are at high risk for prostate cancer due to an inherited mutation. This is trial is for men without prostate cancer, ages 30 to 75, who have tested positive for Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) or BRCA1, BRCA2, HOXB13, ATM, NBN, TP53, CHEK2, PALB2, RAD51C RAD51D, BRIP1, FANCA. The trial involves screening MRI of the prostate every two years and biopsy of the prostate if the MRI is abnormal. There is no cost for travel or study-related tests.

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Genetic Education for Men (GEM Study)

Prostate, Pancreatic

A Study in Hereditary Breast and Ovarian Cancer Families to Provide Men With Up-To-Date Information About the Personal Importance of Genetic Testing (GEM)

The Genetic Education for Men or GEM study, is a clinical trial evaluating educational tools for men from families in which a BRCA1/2 gene mutation has been identified. In order to identify untested men from BRCA1/2 families, we are seeking women who have received positive BRCA1/2 test results and have at least one untested male relative.

Women interested in the study should contact the project coordinator, Mary Kate Ladd, by phone at (877) 687-2720 (toll-free) or by email.

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Pancreatic Cancer Screening Study for High Risk People


A Pancreatic Cancer Screening Study for High Risk Individuals

The purpose of this study is to screen and detect pancreatic cancer and precancer in people with either a strong family history of pancreatic cancer, or an inherited mutation associated with pancreatic cancer risk.

Magnetic Resonance Imaging (MRI) will be used to screen for early stage pancreatic cancer. Participants will also be asked to donate a blood sample at specific intervals for the creation of a blood bank necessary for the development of a blood-based screening test for pancreatic cancer. 

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Denosumab and Mammographic Density in Premenopausal Women With Dense Breasts (TRIDENT)


RANKL Inhibition With Denosumab on Mammographic Density in Premenopausal Women With Dense Breasts (TRIDENT)

The purpose of this study is to evaluate if denosumab can reduce the breast density of premenopausal women who have dense breasts. Denosumab is an FDA-approved injectable medication that is used to treat osteoporosis and to prevent fractures in cancer patients with bone metastases. This study could help us identify novel ways to prevent breast cancer in younger women.

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Study for People with Unexpected Genetic Results

Breast, Ovarian, Pancreatic, Prostate

Genomic Services Research Program Study for People with Unexpected Genetic Results

A new study is recruiting people who received unexpected genetic test results about their cancer risk after having genetic testing done for some other reason.

This is a study of people with "secondary results” from genetic testing. Secondary results are unexpected. They are not related to the reason the person had the genetic test but are shared because they may be very important to the person’s health. Most secondary results have to do with high risks for health problems that can be treated or prevented. Many of these results are related to cancer risk. If you think you have received a secondary result, you may be eligible to join this study.

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IMMray™ PanCan-d Test for Early Detection of Pancreatic Cancer in High-risk Groups


A Study of IMMray™ PanCan-d Test for Early Detection of Pancreatic Cancer in High-risk Groups

This study will validate and evaluate the performance of the IMMray PanCan-d test for pancreatic cancer diagnosis in comparison to standard of care imaging currently used in pancreatic cancer disease surveillance by the research sites’ institutions. ENROLLMENT HAS CLOSED FOR THIS STUDY!

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Pancreatic Cancer Early Detection


Pancreatic Cancer Early Detection Program

This is a study looking at esophageal ultrasound and Magnetic Resonance Imaging (MRI) as a screening for pancreatic cancer in high risk individuals. 

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The WISDOM Study: Women Informed to Screen Depending on Measures of risk

The goal of the Wisdom Study is to determine if breast cancer screening can be made better by personalizing each woman’s mammogram schedule, compared to the current one-size-fits-all, annual approach. The Wisdom Study is designed to end the confusion about when to start and how often to have a mammogram. For more information, visit the WISDOM Study website

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Additional Results on Prevention, Detection & Risk + Screening & Early Detection
74 results
Clinical Trial Official Title
NCT03414125 Effect of Mailed Invites of Choice of Colonoscopy or FIT vs. Mailed FIT Alone on Colorectal Cancer Screening
NCT04473833 Transvaginal Ultrasonography as a Screening Method for Ovarian Cancer
NCT04427527 Accelerating Colorectal Cancer Screening Through Implementation Science in Appalachia
NCT04464668 Colorectal Cancer Awareness, Research and Education and Screening - Rural Expansion, Access and Capacity for Health
NCT03979729 Breast Cancer Screening for Underserved Women: Comparing Outcomes and Lowering Recall Rates With 3D- vs. 2D-mammography
NCT03310892 Tailored Messaging for CRC Screening
NCT04450264 Increasing African Immigrant Women's Participation in Breast Cancer Screening
NCT03250078 A Pancreatic Cancer Screening Study in Hereditary High Risk Individuals
NCT03937453 A Pancreatic Cancer Screening Study in Individuals With New-Onset Diabetes Mellitus
NCT04587258 Improving Cancer Screening and Prevention During the COVID-19 Pandemic in Underserved Populations of Rhode Island
NCT03699995 MoleMapper, Visiomed, and Confocal Microscopy in Screening Participants for Melanoma
NCT03726320 Trial of Community Health Worker-led Decision Coaching
NCT03100461 Adaptive Intervention to Maximize Colorectal Screening in Safety Net Populations
NCT02478892 Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk
NCT04683744 Facilitators and Barriers to Cancer Screening: Stakeholder Perspectives on Implementation
NCT03407417 A Patient-centered Intervention Using Technology to Reduce Colorectal Cancer Disparities in Primary Care
NCT04683731 Helping Patients and Providers Make Better Decisions About Colorectal Cancer Screening
NCT04102722 Safety and Performance of the Multi-Modal UltraSound Tomography (MUST) Device in Breast Cancer Screening
NCT03413605 U01 CRC Project for Vietnamese Americans
NCT03640208 Educate, Assess Risk and Overcoming Barriers to Colorectal Screening Among African Americans
NCT03474913 Upright MRI for Prostate Cancer Screening
NCT02795104 Rural Interventions for Screening Effectiveness
NCT04764292 Screening Contrast-Enhanced Mammography as an Alternative to MRI
NCT04030507 Screening Magnetic Resonance Imaging of the Brain in Patients With Breast Cancer
NCT04671498 Droplet-BC Screening Test for the Detection of Breast Cancer, the DROPLET-BC Study
NCT03729115 A Multi-Modality Surveillance Program for Women at High Risk for Breast Cancer
NCT04414306 Screen to Save 2: Rural Cancer Screening Educational Intervention
NCT04582500 Virtual Colonoscopy Using Omnipaque as a Contrast Agent
NCT04397029 Assessing the Sensitivity of "SureTouch™" in Identifying Clinically Significant Masses in Women Undergoing Diagnostic and Screening Mammography
NCT04192071 Virtual Human Delivered Nutrition Module for Colorectal Cancer Prevention
NCT03859492 Screening CEDM in Intermediate and High-Risk Patient Populations
NCT04763824 KanSurvive: Testing a Model for Improving Cancer Survivorship Care in Rural Practice
NCT04085510 Tomosynthesis vs. Contrast-Enhanced Mammography in Women With Personal History of Breast Cancer in Western Pennsylvania
NCT03623945 Autoantibodies in Breast Cancer Detection
NCT04086771 Southeast Asian Women's Health Project
NCT04761055 Study of iBreast, a Handheld Device to Detect Breast Abnormalities During Screening Visits for Breast Cancer
NCT02980848 Assessing Breast Density's Value in Imaging - A Comparative Effectiveness Study
NCT03471650 Study of PSMA-targeted 18F-DCFPyL PET/CT for the Detection of Clinically Significant Prostate Cancer
NCT03568630 Blood Markers of Early Pancreas Cancer
NCT03264898 Comparative Effectiveness of FITs With Colonoscopy
NCT04583072 Stockholm3 Validation Study in a Multi-Ethnic Cohort
NCT03218423 Longitudinal Performance of Epi proColon
NCT04341129 Abbreviated MRI Protocol: Initial Experience With Dotarem® (Gadoterate Meglumine)
NCT03984695 Sexual Health Empowerment for Women's Health
NCT03715959 Nipple Aspirate Fluid in Detecting Breast Cancer
NCT04192929 Chromoendoscopy or Narrow Band Imaging (NBI) for Improving Adenoma Detection in Colonoscopy
NCT04369053 Prevention of Colorectal Cancer Through Multiomics Blood Testing
NCT04516083 Lynch Syndrome Can be Diagnosed Just From Somatic Mismatch Repair Mutation
NCT04476654 Improving Uptake of Genetic Cancer Risk Assessment in African American Women- Video
NCT04708951 Comparison of Adenoma Detection Rate With ENDOCUFF VISION® vs. G-EYE®
NCT04331535 The Genomic Medicine at VA Study
NCT02206360 Pancreatic Cancer Early Detection Program
NCT04191655 High Definition Colonoscopy (HDC) vs. Dye Spraying Chromo-colonoscopy (DSC) in Screening Patients With Long-standing Inflammatory Bowel Disease (IBD)
NCT04066816 Ellagic Acid, Urolithin and Colonic Microbial Communities Affected by Walnut Consumption
NCT04825834 DNA Evaluation of Fragments for Early Interception - Lung Cancer Training Study (DELFI-L101 Study)
NCT04124900 Telomere Associated Variables (TAVs) in Prostate Cancer
NCT00582296 Multi-Organ Screening Recommendations in Patients With Lynch Syndrome
NCT00539162 Use of the CA 125 Algorithm for the Early Detection of Ovarian Cancer in Low Risk Women
NCT00579514 Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients
NCT00579488 Clinical Significance of Germline BRCA Mutations
NCT03489707 The Prevent Anal Cancer Self-Swab Study
NCT04124406 Voyage: Real-World Impact of the Multi-target Stool DNA Test on CRC Screening and Mortality
NCT04792684 Collection of Samples USOPTIVAL Study
NCT00843375 Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas
NCT04705168 Study of the Nevisense Device to Assess Atypical Skin Lesions
NCT03851133 Florida Pancreas Collaborative Next Generation Biobank
NCT04475640 Cancer Genetic Testing in Ethnic Populations
NCT02217085 Colorectal Polyp Resection Adequacy
NCT04812743 Colorectal Health Research Champions
NCT02140021 Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer
NCT03789162 Blood and Stool Sample Collection in Subjects With a Diagnosis of Colorectal Cancer or Colorectal Lesion: Act Fast
NCT04540081 Enhancing Electronic Health Systems to Decrease the Burden of Colon Cancer, Lung Cancer, Obesity, Vaccine-Preventable Illness, and LivER Cancer
NCT04754347 Computer Aided Detection of Polyps in Colonoscopy
NCT03028831 Fiber to Reduce Colon Cancer in Alaska Native People

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