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Our Featured Research Page lists cancer prevention, treatment and quality of life studies enrolling people with or at high risk for hereditary cancers. You can do a quick search to filter our featured studies by cancer type, study type or key word, or a more in-depth search through clinicaltrials.gov.

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Featured Studies Results

Study Type: Prevention detection risk

The DETECT Study: Detecting Endometrial Cancer in Tampons

The DETECT Study: Detecting Endometrial Cancer in Tampons

Clinicaltrials.gov identifier:
NCT03538665

Prevention
Early detection of endometrial cancer in women over 45 years of age who are undergoing hysterectomy surgery at the University of Alabama

Denosumab for Breast Cancer Risk Reduction in Women With an Inherited BRCA1 Mutation (The Breast Cancer Prevention Study)

Denosumab for Breast Cancer Risk Reduction in Women With an Inherited BRCA1 Mutation (The Breast Cancer Prevention Study)

Clinicaltrials.gov identifier:
NCT04711109

Prevention
Prevention study enrolling women ages 25-55 with a BRCA1 mutation

A Study to Compare Two Surgical Procedures in Women with BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer (SOROCk)

A Study to Compare Two Surgical Procedures in Women with BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer (SOROCk)

Clinicaltrials.gov identifier:
NCT04251052

Prevention
Ovarian cancer prevention for women with a BRCA1 mutation who still have their ovaries

PATROL Study: Prostate Cancer Screening for People AT Genetic Risk FOr Aggressive Disease

PATROL Study: Prostate Cancer Screening for People AT Genetic Risk FOr Aggressive Disease

Clinicaltrials.gov identifier:
NCT04472338

Prevention
Screening study for people with a mutation linked to prostate cancer risk

Pancreatic Cancer Screening Study (CAPS5)

Pancreatic Cancer Screening Study (CAPS5)

Clinicaltrials.gov identifier:
NCT02000089

Prevention
Screening study for people at high risk for pancreatic cancer

Testing A Combination Of Vaccines For Cancer Prevention In Lynch Syndrome

Testing A Combination Of Vaccines For Cancer Prevention In Lynch Syndrome

Clinicaltrials.gov identifier:
NCT05419011

Prevention
Testing A Combination Of Vaccines For Cancer Prevention In Lynch Syndrome

Cancer Prevention Vaccine (Nous-209) for People with Lynch Syndrome

Cancer Prevention Vaccine (Nous-209) for People with Lynch Syndrome

Clinicaltrials.gov identifier:
NCT05078866

Prevention
Prevention study for people with Lynch syndrome

Comparing Screening Methods for Detection of Early-Stage Gastric Cancer in People with a CHD1 Genetic Mutation

Comparing Screening Methods for Detection of Early-Stage Gastric Cancer in People with a CHD1 Genetic Mutation

Clinicaltrials.gov identifier:
NCT04535414

Prevention
Gastric cancer screening study for people with a CHD1 inherited mutation

Screening Study for Men at High Genetic Risk for Prostate Cancer

Screening Study for Men at High Genetic Risk for Prostate Cancer

Clinicaltrials.gov identifier:
NCT03805919

Prevention
Prostate screening with MRI for men with Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) or a BRCA1, BRCA2, HOXB13, ATM, NBN, TP53, BRIP1, CHEK2, PALB2, RAD51C, RAD51D, or other mutation

Testing the Safety And Action of the Investigational Drug REC-4881 in People With Familial Adenomatous Polyposis (FAP)

Testing the Safety And Action of the Investigational Drug REC-4881 in People With Familial Adenomatous Polyposis (FAP)

Clinicaltrials.gov identifier:
NCT05552755

Prevention
Prevention study for people with an APC mutation and FAP who have had colectomy surgery

Testing a Vaccine for Preventing or Treating Triple-Negative Breast Cancer

Testing a Vaccine for Preventing or Treating Triple-Negative Breast Cancer

Clinicaltrials.gov identifier:
NCT04674306

Prevention
Prevention study for people with a BRCA1, BRCA2 or PALB2 inherited mutation who are planning to undergo risk-reducing mastectomy.

Pancreatic Cancer Early Detection for People  at High Risk

Pancreatic Cancer Early Detection for People at High Risk

Clinicaltrials.gov identifier:
NCT04970056

Prevention
Registry and biobank for high risk people undergoing pancreatic cancer screening

Early Detection of Colorectal Cancer for People with Lynch Syndrome

Early Detection of Colorectal Cancer for People with Lynch Syndrome

Clinicaltrials.gov identifier:
NCT05410977

Prevention
People with Lynch Syndrome at risk for colon cancer

WISDOM Study

WISDOM Study

Clinicaltrials.gov identifier:
NCT02620852

Prevention
Study to Determine if Breast Cancer Screening can be Made Better by Personalizing Each Woman’s Mammogram Schedule

Screening in Men at High Risk of Developing Prostate Cancer

Screening in Men at High Risk of Developing Prostate Cancer

Clinicaltrials.gov identifier:
NCT05608694

Prevention
Screening using MRI for men at risk of developing prostate cancer

My Best GI Eating Study

My Best GI Eating Study

Clinicaltrials.gov identifier:
NCT05396846

Prevention
Diet and weight loss study for people who are overweight and at increased risk of colorectal cancer

Risk Reducing Salpingectomy With Delayed Oophorectomy as an Alternative to Risk- Reducing Salpingo-oophorectomy in High Risk-Women

Risk Reducing Salpingectomy With Delayed Oophorectomy as an Alternative to Risk- Reducing Salpingo-oophorectomy in High Risk-Women

Clinicaltrials.gov identifier:
NCT05287451

Prevention
Prevention study for women at high risk for ovarian cancer

Testing the Drug Obeticholic Acid for Familial Adenomatous Polyposis

Testing the Drug Obeticholic Acid for Familial Adenomatous Polyposis

Clinicaltrials.gov identifier:
NCT05223036

Prevention
Prevention study for people with an APC mutation and FAP or AFAP who have polyps in remaining tissue after colectomy surgery

Testing  a Vaccine for Cancer Prevention in People with a BRCA1 or BRCA2 Mutation

Testing a Vaccine for Cancer Prevention in People with a BRCA1 or BRCA2 Mutation

Clinicaltrials.gov identifier:
NCT04367675

Prevention
People with a BRCA1 or BRCA2 mutation

Studying the Use of Naproxen and Aspirin for Cancer Prevention in People with Lynch Syndrome

Studying the Use of Naproxen and Aspirin for Cancer Prevention in People with Lynch Syndrome

Clinicaltrials.gov identifier:
NCT05411718

Prevention
Prevention study for people with Lynch syndrome

Restoring Sensation after DIEP Flap Reconstruction

Restoring Sensation after DIEP Flap Reconstruction

Clinicaltrials.gov identifier:
NCT04533373

Prevention
Study for people undergoing DIEP flap reconstruction

Prostate Cancer Genetic Risk Evaluation and Screening Study (PROGRESS)

Prostate Cancer Genetic Risk Evaluation and Screening Study (PROGRESS)

Clinicaltrials.gov identifier:
NCT05129605

Prevention
People at high risk for prostate cancer due to an inherited mutation

Blood Markers of Early Pancreas Cancer

Blood Markers of Early Pancreas Cancer

Clinicaltrials.gov identifier:
NCT03568630

Prevention
Observational study for people with family history of pancreas cancer or an inherited mutation linked to pancreatic cancer risk.

Helping Latinas Understand Their Risk for Breast Cancer and Get Breast Cancer Care

Helping Latinas Understand Their Risk for Breast Cancer and Get Breast Cancer Care

Clinicaltrials.gov identifier:
NCT05483283

Prevention
Latinas with a high risk of breast cancer

Upright MRI for Prostate Cancer Screening

Upright MRI for Prostate Cancer Screening

Clinicaltrials.gov identifier:
NCT03474913

Prevention
Screening for prostate cancer using upright MRI

Helping People With a Genetic Mutation in BRCA1, BRCA2 or Lynch Syndrome Talk to Their Family Members About Their Risk for Cancer and Find the Best Way to Get Family Members Tested

Helping People With a Genetic Mutation in BRCA1, BRCA2 or Lynch Syndrome Talk to Their Family Members About Their Risk for Cancer and Find the Best Way to Get Family Members Tested

Clinicaltrials.gov identifier:
NCT05677048

Prevention
People with a genetic mutation in BRCA1, BRCA2 or Lynch syndrome who have relatives who have not been tested

Validating a Blood Test for Early Ovarian Cancer Detection in High-risk Women and Families

Validating a Blood Test for Early Ovarian Cancer Detection in High-risk Women and Families

Prevention
Screening study for women with a BRCA1, BRCA2, BRIP1, PALB2, RAD51C, RAD51D, PMS2, MLH1, MSH2, MSH6, or EPCAM mutation

Study for People with Unexpected Genetic Results

Study for People with Unexpected Genetic Results

Clinicaltrials.gov identifier:
NCT02595957

Prevention

If you would like a more in-depth search, visit our In-Depth Search Tool that searches for studies in FORCE’s database and in clinicaltrials.gov


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