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Testing the Drug Obeticholic Acid for Familial Adenomatous Polyposis

Prevention study for people with an APC mutation and FAP or AFAP who have polyps in remaining tissue after colectomy surgery

Clinicaltrials.gov identifier:
NCT05223036
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This study is no longer enrolling patients. 

This Study is Open To:

This study is no longer enrolling patients. 

This Study is NOT Open To:

This study is no longer enrolling patients. 

What the Study Involves

Participants will be divided into two groups:

  • Group 1 will receive OCA for 6 months
  • Group 2 will receive a for 6 months

All participants will undergo GI endoscopy with biopsy and collection of blood samples at screening and on study.

After completion of the study treatment, patients are followed within 14-21 days.

Prevention study for people with an APC mutation and FAP or AFAP who have polyps in remaining tissue after colectomy surgery

Clinicaltrials.gov identifier:
NCT05223036
PRINTER FRIENDLY PAGE