Hereditary Cancer and Genetic Testing

Genes with mutations linked to prostate cancer

Multi-gene panel tests look for inherited mutations in many genes at the same time. These tests may include new or less common genes. Some panels may include additional genes other than those listed below. A genetics expert can make sure that the most appropriate test is ordered based on your personal situation and family medical history. They will also make sure that your test results are interpreted correctly.

Common genes linked to prostate cancer 

Inherited mutations in the following genes have been linked to prostate cancer risk:

  • HOXB13

*Men with inherited mutations in BRCA1 and BRCA2 are more likely to develop metastatic prostate cancer than men without inherited mutations. 

** More research is needed to confirm a link between prostate cancer and an inherited mutation in this gene.

Last updated August 31, 2021