Preimplantation Genetic Diagnosis ()
(also known as Preimplantation Genetic Testing or PGT) is a medical procedure that allows people who carry an inherited mutation linked to cancer—such as , , , etc.—to have children who do not have the mutation. The process is requires the same steps involved in assisted reproductive technology (ART). When the embryos reach a certain size (at day 5-7), a few cells are removed from the outer part of the embryo that would one day form the placenta if it implanted and turned into a pregnancy. The removed cells’ is checked for the presence of the genetic mutation. At the same time, most embryos also are screened to ensure they have the correct number of chromosomes in order to maximize the chance of a successful pregnancy and healthy child. This process identifies the healthiest embryos that do not carry the mutation. These embryos can later be thawed and implanted.
Men with mutations have a 50/50 chance of passing on their mutation to each of their sons and daughters. As with women, men with mutations can prevent passing on the mutation to children through . For men, the process requires their spouse or partner to undergo the steps involved in ART first.
is the only way to determine whether an embryo contains a genetic mutation prior to pregnancy. There is currently no way to test the eggs or sperm for a mutation prior to fertilization.
FORCE offers many peer support programs for people with inherited mutations.
- Our Message Boards allow people to connect with others who share their situation. Once registered, you can post on the Diagnosed With Cancer board to connect with other people who have been diagnosed.
- Our Peer Navigation Program will match you with a volunteer who shares your mutation and situation.
- Our moderated, private Facebook group allows you to connect with other community members 24/7.
- Check out our virtual and in-person support meeting calendar.
- Join one of our Zoom community group meetings.