Keyword: ATM

Article : The cost of cancer care and impact of financial hardship on treatment

Relevance: High

Quality of Writing: High

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Most relevant for: Anyone diagnosed with cancer

Several recent studies on the cost of cancer care show the negative effects on cancer patients. We review an article by Kaiser Health News and associated studies about the financial impact of breast cancer treatment and cost of precision medicine. (2/8/19)

Study : The impact of palbociclib (Ibrance) on overall survival for metastatic breast cancer patients in the PALOMA-3 trial

Relevance: High

Strength of Science: Medium-High

Research Timeline: Post Approval

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Most relevant for: People with metastatic, hormone-positive breast cancer

The PALOMA-3 clinical trial showed that a new CDK4/6 inhibitor in combination therapy improved progression-free survival of women treated for hormone receptor-positive, HER2-negative advanced or metastatic breast cancer in women with prior disease progression after endocrine therapy. This XRAYS reviews a newly published study in the New England Journal of Medicine that looks at overall survival in the original PALOMA-3 study. (1/23/19)

Study : FORCE online survey: What breast cancer information do young women want and where do they look for it?

Relevance: Medium-High

Most relevant for: Young women and the health care providers who treat them

FORCE developed the CDC-funded Examining Relevance of Articles to Young Survivors or XRAYS program to help young breast cancer survivors and those at high-risk better understand media coverage about new breast cancer research. To ensure that the program would be responsive to users’ needs, FORCE designed a web-based survey to assess where young women look for information about breast cancer and to learn their unmet information needs.  The results of this survey were published in the journal Health Communications. (1/18/19)

Study : Improving outcomes for young women with breast cancer: fertility and childbearing issues

Relevance: Medium-High

Strength of Science: Medium-High

Research Timeline: Human Research

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Most relevant for: Women diagnosed with breast cancer at a young age

Fertility issues and family planning decisions are prominent concerns for young women with breast cancer. This XRAYS looks at Dr. Ann Partridge’s presentation at the 2018 San Antonio Breast Cancer symposium. Her talk, “Breast cancer in young women: Understanding differences to improve outcomes," focused on initial findings from the Young Women's Breast Cancer Study. Dr. Partridge’s research continues in the currently enrolling POSITIVE trial which tests whether women can safely interrupt adjuvant endocrine therapy in order to get pregnant. (1/7/19)

Study : Inherited breast cancer in Nigerian women

Relevance: Medium-High

Strength of Science: High

Research Timeline: Post Approval

Most relevant for: Nigerian women or women of Nigerian descent who have breast cancer

A new study shows that among Nigerian women, one in eight cases of breast cancer is due to an inherited mutation in BRCA1, BRCA2, PALB2 or TP53. (12/5/18)

Personal Story : Pamela Munster's story of cancer in the family

Relevance: Medium-High

Quality of Writing: High

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Most relevant for: People with an inherited mutation linked to cancer

In her essay in The Washington Post, Dr. Pamela Munster recounts her family's history with cancer associated with a mutation in the BRCA2 gene. She details her father's extraordinary journey with pancreatic cancer, one of the most aggressive and deadly cancers. (11/27/18)

Article : The importance of racial diversity in clinical trials

Relevance: High

Quality of Writing: High

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Most relevant for: People who are a member of a racial or ethnic minority group

This article by journalists Caroline Chen and Riley Wong looks at racial disparities between participation in clinical trials and the population of people with cancer. (11/6/18)

Este artículo está disponible en español.

Study : Surgeon attitude impacts rate of genetic testing after a breast cancer diagnosis

Relevance: High

Strength of Science: Medium-High

Research Timeline: Post Approval

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Most relevant for: Young women diagnosed with breast cancer who have not yet had genetic testing

A study in JAMA Surgery this year examined the factors that impact genetic testing after a breast cancer diagnosis. This study suggests that the attitudes of attending surgeons about genetic testing have the most impact on whether patients receive testing. (10/6/18)

Article : Cancer experience in families affects decision making

Relevance: Medium-High

Quality of Writing: Medium-High

Most relevant for: Women with an inherited mutation linked to increased risk for cancer

Women with inherited mutations in genes that increase breast and ovarian cancer risk have an additional challenge: coping with how those mutations impact their families and how a family member’s cancer experience can shape their own perception. In a recent U.S. News and World Report article, Elaine Howley explores how a woman's decisions about healthcare, cancer prevention and treatment are affected by experience with cancer in the family. (9/25/18)

Study : Gardening improves health outcomes for breast cancer patients

Relevance: Medium-High

Strength of Science: Medium-High

Research Timeline: Human Research

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Most relevant for: People diagnosed with breast cancer who would benefit from increased activity and from eating more vegetables

Research has shown that adopting a healthier lifestyle may improve overall health and outcomes for cancer survivors. This study looked at a 1-year home-based gardening intervention to increase activity and wellbeing among breast cancer survivors. (08/31/18)