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Categories Cancer Treatment

FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
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Showing 31 through 40 out of 135

Relevance: Medium-High

Most relevant for: People belonging to the LGBTQ+ community

Study: Breast cancer disparities among the LGBTQ+ community

This study looked at differences in breast cancer treatment outcomes among people from the LGBTQ+ community.  (Posted 6/28/23)

Este artículo está disponible en español.

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Relevance: High

Most relevant for: People with HR-positive HER2-negative advanced breast cancer

Study: Breast cancer outcomes improved with CDK4/6 inhibitor treatment

A study showed that people with metastatic breast cancer who took an oral drug known as a CDK4/6 inhibitor combined with hormone therapy did better than people who took hormone therapy alone. The drug combination improved the length of time before cancer worsened or returned. After six years of treatment, people who took this drug combination lived longer compared to those who took hormone therapy alone. (Posted 4/5/23)

Este artículo está disponible en español.

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Relevance: High

Most relevant for: People with HR-positive, HER2-negative advanced breast cancer

Study: New oral drug treatment for some advanced breast cancer

The FDA has approved a new oral drug called Oserdu for the treatment of HR-positive, HER2-negative advanced breast cancer. A blood test was also approved to help doctors identify patients who would benefit most from this new treatment. (Posted 3/20/23)

Este artículo está disponible en español.

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Relevance: Medium-High

Most relevant for: People with metastatic castration-resistant prostate cancer (mCRPC)

Study: Promising early results for treating metastatic prostate cancer

The TALAPRO studies looked at how well the oral drug Talzenna (talazoparib) works as a treatment for metastatic castration-resistant prostate cancer (mCRPC). The addition of Talzenna to treatment with Xtandi (enzalutamide) increased the time until the cancer got worse or came back (progression-free survival). The greatest benefit was seen in people who had an inherited or tumor mutation in a gene that repairs DNA damage (such as ATM, BRCA1, BRCA2 and others). (Posted 3/1/23)

Update: On June 20, 2023, the Food and Drug Administration (FDA) approved the combination of Talzenna with Xtandi as an initial treatment for some people with mCRPC for people with inherited or tumor mutations in genes that repair DNA damage. 

Este artículo está disponible en español.

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Relevance: High

Most relevant for: People with early-stage breast cancer who are post-menopausal

Study: Treatment to reduce bone fractures also improves breast cancer survival in postmenopausal people

A large study looked at the effects of adding the bone-protective drug denosumab (Prolia), to standard hormone therapy for the treatment of early-stage, postmenopausal, HR-positive breast cancer. The researchers found that adding denosumab to aromatase inhibitor hormonal therapy improved bone health, disease-free survival and overall survival. (Posted 2/27/23)

Este artículo está disponible en español.

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Relevance: Medium-High

Most relevant for: People with ER/PR-positive, HER2-negative metastatic breast cancer

Study: Trodelvy benefits people with advanced hormone-positive metastatic breast cancer

The study TROPiCS-2 showed that the drug Trodelvy (sacituzumab govitecan) improved progression-free survival when compared to chemotherapy in people with advanced metastatic ER/PR-positive, HER2-negative breast cancer who have few other treatment options. This drug does not yet have FDA approval for use in the hormone-positive setting. (Posted 1/18/23)

Update: On 02/03/2023 the FDA approved Trodelvy for patients with locally advanced or metastatic  breast cancer who have received hormonal therapy and at least two other types of treatment in the metastatic setting.

Este artículo está disponible en español.

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Relevance: Medium

Most relevant for: People with a BRCA1 or PALB2 mutation undergoing prophylactic bilateral mastectomy

Update: Breast cancer vaccine trial begins enrolling people with BRCA1 and PALB2 mutations

A new vaccine was first tested on people diagnosed with triple-negative breast cancer. The vaccine is now being tested to prevent breast cancer among people with an inherited mutation in BRCA1 or PALB2 who are at high risk and who are planning to have a risk-reducing mastectomy. (Posted 1/9/23) Este artículo está disponible en español.

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Relevance: High

Most relevant for: People with advanced ovarian cancer

Study: What influences aggressive end-of-life care for ovarian cancer?

Aggressive medical treatment is often given to people with terminal ovarian cancer when prior treatment has stopped working. This aggressive end-of-life treatment conflicts with clinical guidelines, may increase pain and suffering and does not extend life. This study found that the end-of-life care that a person with ovarian cancer receives is influenced by their doctors. (Posted 1/3/23)

Este artículo está disponible en español.

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Relevance: Medium-High

Most relevant for: Men with breast cancer

Study: Male breast cancer: Patient and surgeon experiences

By surveying male breast cancer patients and the surgeons who treat them, researchers gained insight into the experiences of both groups, shedding light on an important issue for men with breast cancer. (Posted 12/22/22)

Este artículo está disponible en español.

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Relevance: Medium-High

Most relevant for: People currently undergoing treatment for cancer

Guideline: Guidelines on exercise, diet, and weight during cancer treatment

Most professional guidelines on exercise, diet and weight management have focused on the health of the general population and cancer survivors. The American Society of Clinical Oncology (ASCO) has now published evidence-based recommendations for exercise, diet and weight specifically for people who are in active treatment for cancer. (Posted 11/29/22)  Este artículo está disponible en español.

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