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Screening for high risk men
The National Comprehensive Cancer Network (NCCN) has guidelines for cancer screening in men who are at high risk for cancer due to an inherited mutation.
- Black men should consider annual screening with and DRE beginning at age 40.
- Men with an inherited mutation, should begin annual screening with and DRE at age 40.
- Men with an inherited , or mutation should consider annual screening with and DRE beginning at age 40.
- There has not been enough research to show a benefit from early, or annual screening for cancer in men who have an , , , , , , , or other mutations linked to cancer. For these men, experts recommend managing these risks based on family history of cancer.
Men at high risk for cancer should consider enrolling in a screening clinical trial.
Screening for average risk men
There are several different guidelines for cancer screening in average risk men:
- NCCN recommends beginning at age 45, men should have a conversation with their doctor about their risk for cancer and the benefits, risks and limitations of cancer screening using and DRE.
- For men who choose to undergo screening, and DRE should be performed every 2-4 years as long as DRE is normal and is low (<1 ng/ml).
- For men with slightly elevated of 1-3 ng/ml and normal DRE, screening should be repeated every 1-2 years.
- After age 75, screening every 1-4 years should be considered for healthy men.
- The U.S. Preventive Services Task Force () recommends that men who are 55 to 69 years old should talk to their doctor about the benefits and harms of screening for cancer and make their own decisions about being screened for cancer with a specific antigen () test.
- Men who are 70 years old and older should not be screened for cancer routinely.
- The American Cancer Society (ACS) recommends beginning at age 50, men should discuss the benefits, risks, and limitations of cancer screening with their doctor in order to make an informed decision about whether to be screened for cancer.
- For men who choose screening, and DRE should be performed every 2 years as long as DRE is normal and is low (<2.5 ng/ml).
- For men who choose screening, and DRE should be performed every year if DRE is normal and is 2.5 ng/ml or higher.
The following resources can help you locate an expert near you or via telehealth.
Finding urologists
- WebMD has a tool to help people find an expert near them. To find a urologist near you, type " cancer" into the text field.
Sexual health experts
Some types of cancer treatment may affect sexual health.
- The Sexual Medicine Society of North America (SMSNA) has a search tool to find experts in your area who sexual health care services.
- The American Association of Sexuality Educators, Counselors and Therapists (AASECT) maintains a tool to help people find a sexual health expert near them.
Other ways to find experts
- Register for the FORCE Message Boards and post on the Find a Specialist board to connect with other people who share your situation.
- The National Cancer Institute (NCI)-Designated Comprehensive Cancer Centers have specialists to manage the symptoms and side effects of cancer prevention or treatment.
The following are studies looking at ways to screen for cancer in people at high risk:
- NCT05129605: Cancer Genetic Risk Evaluation and Screening Study (PROGRESS). This study will look at how enhanced cancer screening using will improve early detection rates and further understanding of how inherited mutations can lead to development of cancer.
- NCT03805919: Men at High Genetic Risk for Cancer. This is a cancer screening study using in high risk men. This study is open to men with an in any of the following genes: , , , , , , , , , , , , , , or FANCA.
- NCT04472338: Screening for Men With Inherited Risk of Developing Aggressive Cancer, PATROL Study. This study is looking at ways to detect cancer earlier in men who are at increased genetic risk of developing cancer that forms, grows, or spreads quickly (aggressive). The study is open to men with mutations associated with cancer risk.
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NCT05608694: Screening in Men at High Risk of Developing Cancer. The purpose of this study is to determine whether or not Magnetic Resonance Images () will identify high-grade cancers earlier and more frequently in men at high risk of developing cancer.