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Risk Management
Read about different genes that are linked to hereditary cancer, their associated risks and guidelines for screening, preventing and treating cancers in people with inherited mutations in these genes.
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Risk Management for People with Inherited Mutations

The National Comprehensive Cancer Network (NCCN) provides risk management guidelines for people with mutations. We recommend that you speak with a genetics expert who can look at your personal and family history of cancer and can help you decide on a plan to manage your risk. You can learn more about risk management options in our section on Screening and Risk Reduction by Cancer Type

cancer screening

Experts recommend:

  • By age 40, you should have a conversation with your doctor about the potential benefits, risks, costs and limitations of screening for cancer.
  • If you choose to have screening, the guidelines recommend an annual digital rectal exam and Specific Antigen () test. 

Other cancer screening and prevention

There has not been enough research to show a benefit from screening and prevention for other cancers in people who have a mutation. For this reason, experts recommend managing these risks based on family history of cancer. 

Last updated December 31, 2023

Get Support
Get Support

FORCE offers many peer support programs for people with inherited mutations. 

updated: 08/06/2022

Open Clinical Trials
Open Clinical Trials

The following are studies looking at ways to screen for cancer in people at high risk: 

updated: 03/12/2023