Genes linked to hereditary endometrial cancer
Multi-gene panel tests look for inherited mutations in many genes at the same time. These tests may include new or less common genes. Some panels may include additional genes other than those listed below. A genetics expert can make sure that the most appropriate test is ordered based on your personal situation and family medical history. They will also make sure that your test results are interpreted correctly.
Common genes linked to hereditary endometrial cancer
The most common inherited gene mutations associated with hereditary endometrial cancer are:
- Genes associated with Lynch syndrome
- PTEN (Cowden syndrome)
- STK11 (Peutz-Jeghers syndrome)
A rare type of endometrial cancer, uterine serous carcinoma, has also been associated with BRCA mutations. However, this remains under investigation.