Hereditary Cancer and Genetic Testing

General information for people with inherited  mutations

Both men and women can carry a mutation in . Inherited mutations in are associated with .

People with an inherited mutation in  have increased risk for certain cancers. The lifetime cancer risk for people with is high, and many people have more than one cancer. See our Cancer Risk section for more information. 

There are guidelines for screening and prevention for certain cancers in people with a mutation. See our Risk Management section for more information about screening and prevention options in people with this mutation.

People with an inherited mutation who have been diagnosed with cancer may qualify for specific treatments or clinical trials. Visit our Cancer Treatment section for more information.

Certain families with mutations may have Li-Fraumeni-like syndrome.  See our Other Considerations section for more information about this disease.

The (tumor suppressor protein 53 or p53) gene is located on chromosome 17. helps in the repair of damaged

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FORCE offers many peer support programs for people with inherited mutations. 

updated: 03/12/2022

Last updated March 19, 2022