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FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
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1 through 10 of 93

Relevance: High

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Strength of Science: High

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Research Timeline: Post Approval

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Study : Birth control pills may offer long-term protection against endometrial and ovarian cancer

Most relevant for: People concerned about endometrial, ovarian or breast cancer risk

A large study showed that birth control pills may protect against endometrial and ovarian cancers, even years after use was discontinued. (posted 6/1/21)

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Birth control pills may offer long-term protection against endometrial and ovarian cancer

Relevance: High

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Strength of Science: High

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Research Timeline: Post Approval

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Study : Daily high-dose aspirin taken for at least 2 years reduces the risk of colorectal cancer but not other cancers in people with Lynch syndrome

Most relevant for: People with Lynch syndrome

Research has shown that daily aspirin use can reduce the risk of colon and other cancers. The Cancer Prevention Program 2 (CaPP2) study looked at the effect of daily aspirin in patients with Lynch syndrome. After 10 years of follow-up, the results showed that taking daily aspirin for two years reduced the frequency of colon cancer in patients with Lynch syndrome, and importantly, did not result in an increase in side-effects or complications. No benefit was seen for other Lynch syndrome-related cancers, including endometrial cancer. (5/17/21)

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Daily high-dose aspirin taken for at least 2 years reduces the risk of colorectal cancer but not other cancers in people with Lynch syndrome

Relevance: Medium-High

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Strength of Science: High

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Update : Cancer disparities: Colorectal cancer in African Americans

Most relevant for: African Americans concerned about colorectal cancer

The American Association for Cancer Research (AACR) released a 2020 report about cancer disparities among racial and ethnic groups in the United States. In this XRAY review, we highlight data from the report about the burden of colorectal cancer in African Americans, who have the highest rates of diagnosis and death related to the disease among all racial and ethnic groups. (Posted 4/27/21)

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Cancer disparities: Colorectal cancer in African Americans

Relevance: Medium-High

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Strength of Science: Medium-High

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Research Timeline: Post Approval

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Study : Body Mass Index (BMI) may affect how well aspirin use protects against colorectal and ovarian cancer

Most relevant for: People concerned about their risk of colorectal or ovarian cancer.

This study looked at the impact of daily aspirin use for lowering the risk for multiple types of cancers and whether this risk reduction can be modified by cancer risk factors such as obesity, smoking, physical inactivity or a family history of cancer. (3/19/21)

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Body Mass Index (BMI) may affect how well aspirin use protects against colorectal and ovarian cancer

Relevance: Medium-High

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Strength of Science: Medium-High

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Research Timeline: Human Research

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Study : Breastfeeding may lower risk of ovarian cancer in women with BRCA mutations

Most relevant for: Women considering breastfeeding who have inherited BRCA mutations.

Data from a large-scale study suggests that breastfeeding may protect against ovarian cancer in women with inherited mutations in BRCA1 or BRCA2. (1/28/21)

Este artículo está disponible en español.

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Breastfeeding may lower risk of ovarian cancer in women with BRCA mutations

Relevance: High

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Research Timeline: Post Approval

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Update : FDA approves new imaging drug for detecting spread of prostate cancer

Most relevant for: Men with prostate cancer

On December 1, 2020 the FDA approved a new type of imaging technology to confirm the spread of newly diagnosed prostate cancer that is suspected to be metastatic. The approval also includes use for confirming suspected recurrence in men who have rising PSA after treatment. The approval is based on two clinical trials that showed this new technique to be safe and consistent in accurately detecting cancer that has spread beyond the prostate gland. (1/7/21)

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FDA approves new imaging drug for detecting spread of prostate cancer

Relevance: Medium-High

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Strength of Science: Medium-High

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Research Timeline: Human Research

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Study : Women support delayed removal of ovaries

Most relevant for: Women at high risk of ovarian cancer who are considering undergoing risk-reducing surgery.

Risk-reducing early removal of fallopian tubes followed by removal of ovaries at a later date was acceptable to women at high risk of ovarian cancer due to an inherited mutation in a recent study.  This was especially true for women worried about sexual dysfunction associated with surgical menopause. (12/24/20)

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Women support delayed removal of ovaries

Relevance: Medium

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Strength of Science: Medium

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Research Timeline: Post Approval

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Study : Inherited gene mutations found in pancreatic cancer families in Spain

Most relevant for: People with pancreatic cancer and a family history of pancreatic or other cancers

This study looked for inherited mutations in genes known to be linked to hereditary pancreatic cancer. The results provide additional evidence that most hereditary pancreatic cancer is due to inherited mutations in genes that were previously associated with other forms of cancer. (10/29/20)

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Inherited gene mutations found in pancreatic cancer families in Spain

Relevance: Medium-High

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Strength of Science: Medium-High

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Research Timeline: Post Approval

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Study : Knowing about an inherited BRCA mutation improves outcomes for women with breast cancer

Most relevant for: Young women with, or at high risk for an inherited BRCA mutation

Inherited mutations in the BRCA1 and BRCA2 genes are linked to a high lifetime risk of breast and other cancers. This study shows that women who know that they have a BRCA mutation before they are diagnosed with breast cancer have improved outcomes including diagnosis at earlier stages and improved overall survival. (10/26/20)

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Knowing about an inherited BRCA mutation improves outcomes for women with breast cancer

Relevance: Medium-Low

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Strength of Science: Medium-Low

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Research Timeline: Human Research

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Study : Dairy milk may slightly raise breast cancer risk

Most relevant for: Women who consume dairy or soy

Debate continues about whether consuming soy or dairy products increases breast cancer risk. This study looked at a large number of women and found no link between soy and breast cancer risk. The study did find that postmenopausal women who drank dairy milk have a small increase in breast cancer risk. (09/04/20)

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Dairy milk may slightly raise breast cancer risk