FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you.
XRAY is a reliable source of hereditary cancer research-related news and information.
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Hereditary Cancer Risk
Update : Breast cancer vaccine trial begins enrolling people with BRCA1 and PALB2 mutations
Most relevant for: People with a BRCA1 or PALB2 mutation undergoing prophylactic bilateral mastectomy
A new vaccine was first tested on people diagnosed with triple-negative breast cancer. The vaccine is now being tested to prevent breast cancer among people with an inherited mutation in BRCA1 or PALB2 who are at high risk and who are planning to have a risk-reducing mastectomy. (Posted 1/9/23) Este artículo está disponible en español.
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Relevance: High
Strength of Science: Medium-High
Research Timeline: Human Research
Study : Prostate cancer screening may benefit people with Lynch syndrome
Relevance: High
Strength of Science: Medium-High
Research Timeline: Human Research
Most relevant for: People with Lynch syndrome
Initial results from the IMPACT trial show that PSA testing to screen for prostate cancer in people with Lynch syndrome can detect aggressive early prostate cancers. These findings support the use of PSA screening in men with Lynch syndrome, particularly men with an inherited mutation in an MSH2 or MSH6 gene. (Posted 11/10/22)
Este artículo está disponible en español.
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Relevance: Medium-High
Strength of Science: High
Research Timeline: Post Approval
Study : Resistant starch may help prevent some cancers in people with Lynch syndrome
Relevance: Medium-High
Strength of Science: High
Research Timeline: Post Approval
Most relevant for: People with Lynch syndrome and people with a personal and/or family history that suggests Lynch syndrome
This study looked at whether a type of nutrient known as resistant starch could lower the risk of cancers in people with Lynch Syndrome. Researchers found that resistant starch can reduce the risk of non-colorectal cancers but not colorectal cancer. (Posted 10/17/22)
Este artículo está disponible en español.
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Relevance: Medium-High
Strength of Science: Medium-High
Study : Teens and young adults respond well to learning about familial cancer risk
Relevance: Medium-High
Strength of Science: Medium-High
Most relevant for: Mothers who have had genetic testing for BRCA1 or BRCA2 whether or not they have been diagnosed with breast or ovarian cancer
Little is known about how awareness of hereditary cancer in a high-risk family affects the quality of life of teens and young adults. This study looked at the lifestyle choices, cancer awareness and quality of life of adolescents and young adults whose mothers had undergone testing for a BRCA mutation. (Posted 10/11/2022) Este artículo está disponible en español.
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Update : FDA reports on new cancers linked to breast implants
Most relevant for: People with breast implants
New cancers have been found in women with both textured and smooth implants that are filled with either saline or silicone. These cancers are extremely rare. The FDA has reported cases of a type of skin cancer and blood cancers in the scar tissue that forms around breast implants. The newly reported lymphomas are different from the previously reported breast implant-associated anaplastic large cell lymphoma (BIA-ALCL). (Posted 9/27/22). Este artículo está disponible en español.
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Relevance: High
Strength of Science: High
Research Timeline: Post Approval
Study : Screening for pancreatic cancer detects early-stage disease and improves survival
Relevance: High
Strength of Science: High
Research Timeline: Post Approval
Most relevant for: People at increased risk for pancreatic cancer because of family history or an inherited mutation.
A research study has shown that screening for pancreatic cancer in people with an inherited mutation or family history was able to detect early-stage pancreatic cancers and improve survival. These results will likely change pancreatic cancer screening guidelines for high-risk individuals (Posted 8/30/22)
Este artículo está disponible en español.
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Article : Rise in endometrial cancer affects Black women more than white women
Most relevant for: People concerned about their risk for endometrial cancer
The New York Times calls attention to the increase in a type of cancer of the uterus called endometrial cancer and how it disproportionately affects Black women. The article provides useful information about endometrial cancer while raising awareness of a significant and growing health disparity. (Posted 8/16/22)
Este artículo está disponible en español.
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Relevance: High
Quality of Writing: Medium-High
Article : How your ovarian cancer diagnosis can help your relatives
Relevance: High
Quality of Writing: Medium-High
Most relevant for: People diagnosed with ovarian cancer
This media article provides tips from experts and the CDC for talking to family members after a diagnosis of ovarian cancer. It highlights which family members may be at risk of developing ovarian cancer or passing on genes that increase risk. The article provides links to resources, talking points, alternative methods of communication and potential reactions. (Posted 7/28/22)
Este artículo está disponible en español.
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Relevance: Medium-High
Strength of Science: High
Research Timeline: Human Research
Study : Risk-reducing ovarian cancer surgery and quality of life
Relevance: Medium-High
Strength of Science: High
Research Timeline: Human Research
Most relevant for: People with an inherited BRCA mutation
People with an inherited BRCA gene mutation are recommended to have surgery to remove their ovaries before the age of natural menopause to reduce their risk of ovarian cancer. This surgery can cause short-term and long-term effects. This study assesses the quality of life among people who have their fallopian tubes surgically removed and later have their ovaries removed compared to people who have their ovaries and fallopian tubes removed at the same time. (Posted 7/26/22). Este artículo está disponible en español.
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Relevance: Medium
Strength of Science: Medium
Research Timeline: Post Approval
Study : Do artificial sweeteners increase the risk of cancer?
Relevance: Medium
Strength of Science: Medium
Research Timeline: Post Approval
Most relevant for: People who consume artificial sweeteners
A large study of adults in France suggests that artificial sweeteners may increase the risk of certain cancers. (posted 6/21/2022). Este artículo está disponible en español.
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