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HOXB13: Options for Cancer Treatment
Learn about treatment options for people with a HOXB13 mutation. Stay up to date by signing up for our community newsletter.
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Cancer Treatment for People with an Inherited Mutation
Does a HOXB13 mutation affect cancer treatment options?
Some research has linked HOXB13 mutations to an increased risk for more aggressive cancer. But not all research studies on aggressive prostate cancer have found a connection to HOXB13.
Currently there are no targeted treatments or guidelines specifically for people with a HOXB13 mutation. People with a HOXB13 mutation who have been diagnosed with cancer may benefit from testing and may qualify for clinical trials looking for more effective treatments for cancer.
To learn more about standard-of-care treatment options, visit our section on Prostate Cancer Treatment Options.
More Resources

Guidelines for Early-Stage Prostate Cancer
Guidelines for people with early-stage prostate cancer.
Guidelines for Advanced-Stage Prostate Cancer
Guidelines for people with advanced-stage prostate cancer.
FORCE partner, ZERO Prostate Cancer has detailed information on staging and treatment of prostate cancer and other resources for patients.
Last updated May 27, 2025