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HOXB13: Options for Cancer Treatment

Learn about treatment options for people with a HOXB13 mutation. Stay up to date by signing up for our community newsletter.
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Cancer Treatment for People with an Inherited HOXB13 Mutation

Does a mutation affect cancer treatment options?

Some research has linked HOXB13 mutations to an increased risk for more aggressive cancer. But not all research studies on aggressive prostate cancer have found a connection to HOXB13. 

Currently there are no targeted treatments or guidelines specifically for people with a HOXB13 mutation. People with a HOXB13 mutation who have been diagnosed with cancer may benefit from testing and may qualify for clinical trials looking for more effective treatments for cancer. 

To learn more about standard-of-care treatment options, visit our section on Prostate Cancer Treatment Options

More Resources

Guidelines for Early-Stage Prostate Cancer

Guidelines for people with early-stage prostate cancer.

Guidelines for Advanced-Stage Prostate Cancer

Guidelines for people with advanced-stage prostate cancer.
FORCE partner, ZERO Prostate Cancer has detailed information on staging and treatment of prostate cancer and other resources for patients.
Last updated May 27, 2025