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Surveys, Registries, Interviews
This study will enroll Li-Fraumeni Syndrome patients, family members, and household members. Patients and family/household members may be enrolled with informed consent

Clinical and Molecular Studies of Li-Fraumeni Syndrome and TP53-Associated Disorders

The Li-Fraumeni Syndrome Biobank (LFSBB) study is a biobank that collects specimens such as blood and other biomedical samples for individuals who have Li-Fraumeni Syndrome (LFS), unaffected relatives, and household members.

Clinicaltrials.gov identifier: NCT04367246
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Prevention
Screening study for people at high risk for pancreatic cancer

Pancreatic Cancer Screening Study (CAPS5)

CAPS5 is a study looking at screening for early cancer in people with an elevated lifetime risk of developing pancreatic cancer. The goal is to study biomarkers derived from images and tissue samples (blood, pancreas fluid, duodenal fluid) for the early detection of pancreatic cancer and precancerous lesions.

 

Clinicaltrials.gov identifier: NCT02000089
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Treatment
Treatment study for people with intermediate- or high-risk prostate cancer with certain tumor mutations

NePtune: Using PARP Inhibitors Before Surgery in Localized Prostate Cancer

This research study is enrolling prostate cancer patients who plan to undergo surgery to have their prostate removed (radical prostatectomy) and whose cancer has one of the listed gene mutations: ATM, BRCA1, BRCA2, CHEK2, PALB2, RAD51B, RAD51C, RAD51D, RAD54L2, BARD1, FANCA or BRIP1.

Clinicaltrials.gov identifier: NCT05498272
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Treatment
Treatment study for people with advanced or metastatic cancers

Treating Advanced Cancers with BRCA or Other Related Gene Mutations Using Targeted Therapy MOMA-313 Alone or In Combination with the PARP Inhibitor Olaparib

This trial will study the safety, tolerability, and initial effectiveness of MOMA-313, a new type of targeted therapy, alone or in combination with the PARP inhibitor olaparib to treat people with advanced or metastatic cancers with certain types of mutations.

Clinicaltrials.gov identifier: NCT06545942
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Surveys, Registries, Interviews
Survey for women with a BRCA1, BRCA2, PALB2, RAD51C, RAD51D genetic mutation who have undergone risk-reducing bilateral salpingo-oophorectomy (removed both tubes and ovaries) to lower cancer risk

Hormone Replacement Therapy After Risk-Reducing Surgery in Women at Increased Risk for Breast Cancer: The Patient Perspective

This study will explore the decision making surrounding hormone replacement therapy (HRT) in women (AFAB) aged 35-50 with a BRCA1, BRCA2, PALB2, RAD51C, RAD51D genetic mutation  who have undergone risk-reducing bilateral salpingo-oophorectomy (removed both tubes and ovaries) to lower cancer risk.

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Treatment
Men aged 18 years or older with metastatic prostate cancer

Pfizer Clinical Trials for Metastatic Prostate Cancer are Now Enrolling

The study will determine whether the study medicine mevrometostat can delay or stop the growth of metastatic prostate cancer. Mevrometostat is thought to work by blocking the abnormal EZH2 activity in cells, which may help prevent or delay hormone therapy resistance and cancer growth and progression.

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Prevention
Pancreatic cancer screening study for people with ATM, BRCA1, BRCA2 or PALB2 mutations

Pancreatic Cancer Screening Study for People with ATM, BRCA1, BRCA2 or PALB2 Mutations

This study will look at how often routine MRI scans detect abnormal findings in people with inherited mutations in BRCA1, BRCA2, ATM, and PALB2, who are undergoing pancreatic cancer screening. Researchers want to learn how often MRI and endoscopic ultrasound (EUS) yield abnormal results, and how frequently they find pancreatic cancer or precancer. The study will also review the rate of procedures like biopsies and surgeries among participants. 

Clinicaltrials.gov identifier: NCT05058846
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Treatment
Treatment study for people with advanced solid tumors

Study of a New InvestigationaI Inhibitor to Treat People with Advanced Solid Tumors

The study will test if an investigational treatment, XL309, is safe and works when used alone or in combination with a PARP inhibitor to treat people with some advanced solid tumors. The study is enrolling people with BRCA1 or BRCA2 inherited mutations and have HER2-negative breast cancer, prostate cancer, pancreatic cancer, high grade ovarian, fallopian tube or primary peritoneal cancer; or other solid tumors with certain genetic mutations. 

Clinicaltrials.gov identifier: NCT05932862
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Quality of Life
An online study comparing two educational interventions for female cancer survivors experiencing sexual health changes

Sexual Health and Rehabilitation Online (SHAREonline): An Educational Intervention for Young Women after Cancer

SHAREonline compares two brief educational interventions conducted by videoconference to learn if they help women age 19-49 manage sexual function changes after cancer treatment.

Clinicaltrials.gov identifier: NCT06458049
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Treatment
This is a treatment study enrolling people with advanced or metastatic solid tumors with known STK11 mutations

Study of the drug TNG260 and an Immunotherapy in Advanced Solid Tumors With a STK11 Mutation

The study is designed to find the safest dose of a drug called TNG260, given along with a standard dose of the immunotherapy drug pembrolizumab, in people with advanced or metastatic solid tumors and have a STK11 genetic mutation.

Clinicaltrials.gov identifier: NCT05887492
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Prevention
Testing a combination of vaccines for cancer prevention in Lynch syndrome

Lynch Syndrome Vaccine Study

This study is being done to assess the safety and effectiveness of a series of vaccines (Tri-Ad5), together with another drug (N-803) that magnifies the body’s response to vaccines, to see if there is an effect on the risk of developing colon and other cancers in LS patients.

Clinicaltrials.gov identifier: NCT05419011
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Surveys, Registries, Interviews
This population-based research study aims to enroll at least 10,000 people aged 18 and older who live in the United States. A diagnosis of cancer is NOT required. Participants may receive information about their genetic ancestry for free

Research Study on the Genetics of Breast Cancer

We are conducting a fully-online research study to learn more about how genes affect your risk of breast cancer. No office visit is required. Participants provide consent online, answer questions online about their health and medical history, and provide DNA via a saliva sample using a pre-paid mailer through the mail. In return for participation, study participants may receive information about their genetic ancestry for free.

Clinicaltrials.gov identifier: NCT06773897
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Surveys, Registries, Interviews
A screening registry for people diagnosed with prostate cancer

PROMISE Registry: A Prostate Cancer Registry of Outcomes and Germline Mutations for Improved Survival and Treatment Effectiveness

PROMISE is a nationwide registry of prostate cancer patients with inherited mutations; screening approximately 5,000 participants with a prostate cancer diagnosis. The PROMISE team is studying how these mutations affect patient outcomes and hope to help patients learn more about their disease, the treatments that they may benefit most from, and any research studies that they may be eligible for.

Clinicaltrials.gov identifier: NCT04995198
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This is a study for women diagnosed with BRCA 1 or BRCA2 focused on increasing education on options for reducing cancer risk associated with their diagnosis

Acting on Cancer Testing Together (ACT-Together)

The goal of this research study is to develop a new education program, called the ACT-Together intervention, to educate and support women who test positive for the BRCA1 or BRCA2 mutation on how they can reduce their risk of cancer in an online group setting.

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VIRTUAL

Surveys, Registries, Interviews
Survey to share your views on a new method to track research specimens

What Happens to Tissue or Blood Samples you Donate as Part of Research?

Survey to share your views on a new method to track research specimens, like tissue or blood, you or your loved ones may have donated for science

More info    ›

Prevention
Ovarian cancer prevention for women with a BRCA1 mutation who still have their ovaries

A Study to Compare Two Surgical Procedures in Women with BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer (SOROCk)

SOROCk [NRG-CC008] is a clinical trial studying if removal of just the fallopian tubes can reduce the risk of ovarian cancer nearly as much as removing both the ovaries and fallopian tubes among women with an inherited BRCA1 mutation. The main benefit of removing only the fallopian tubes and not the ovaries is to prevent surgically-induced menopause. The study will also examine various patient-reported quality of life outcomes. Researchers believe that most ovarian cancers first begin in the fallopian tubes, suggesting that removing the fallopian tubes only may prevent the development of ovarian cancer. This concept has never been formally testing in a clinical trial.

Clinicaltrials.gov identifier: NCT04251052
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Surveys, Registries, Interviews
Study collecting blood samples and imaging records of people at high risk of developing pancreatic cancer

Registry for People at Increased Risk for Pancreatic Cancer

This study will collect blood samples and MRI images from people at an increased risk of developing pancreatic cancer in order to improve early-stage detection methods in the future. 

Clinicaltrials.gov identifier: NCT06151223
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Treatment
Treatment for women diagnosed with platinum-resistant ovarian, fallopian tube, or primary peritoneal cancer or whose cancer did not respond to prior chemotherapy

Study of the Drug Olvi-Vec in Women with Ovarian Cancer

This study will test how safe and effective the immunotherapy drug Olvi-Vec is, when it is followed by further chemotherapy and the drug bevacizumab in women diagnosed with platinum-resistant or platinum-refractory ovarian, fallopian tube or primary peritoneal cancer.

Clinicaltrials.gov identifier: NCT05281471
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Prevention
Prevention study for people with an APC mutation and FAP who have had colectomy surgery

Testing the Safety And Action of the Investigational Drug REC-4881 in People With Familial Adenomatous Polyposis (FAP) (TUPELO Study)

This study is looking at how safe and effective the research drug REC-4881 is for treating polyps in people with Familial Adenomatous Polyposis (FAP). Participants will receive the oral drug REC-4881. A participant's dose will depend on when they join the study. 

Clinicaltrials.gov identifier: NCT05552755
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VIRTUAL

Surveys, Registries, Interviews
VOICES of Black Women is a study led by the American Cancer Society to better understand cancer and other health conditions among Black women

The American Cancer Society’s “VOICES of Black Women” Observational Study

VOICES of Black Women is an observational research study to better understand cancer and other health conditions among Black women. VOICES is enrolling Black women ages 25-55 in the United States who have never been diagnosed with cancer.

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Treatment
Treatment study for people with advanced breast cancer who have a BRCA1 or BRCA2 genetic mutation and who were previously treated with a PARP inhibitor

Olaparib with Cediranib or Ceralasertib for People with Advanced or Metastatic Breast Cancer and with a BRCA1 or BRCA2 Mutation

This study is for people with advanced or metastatic breast cancer, have a BRCA1 or BRCA2 genetic mutation and were previously treated with a PARP inhibitor. The study will examine how effective  Olaparib in combination with Cediranib or Ceralasertib is in reducing the size of cancer and determining the length of time patients respond well to the treatment.

Clinicaltrials.gov identifier: NCT04090567
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Treatment
Treatment study for metastatic, castration-sensitive prostate cancer

Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents (EvoPAR-PR01)

This study will evaluate an investigational PARP inhibitor drug called Saruparib in combination with new hormonal agents in the treatment of metastatic prostate cancer, compared to the current standard treatment available. The study will enroll people whose tumors have mutations in the following genes: BRCA1, BRCA2, ATM, BARD1, CDK12, PALB2, RAD51B, RAD51C, RAD51D

Clinicaltrials.gov identifier: NCT06120491
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Treatment
Treatment study for people with metastatic pancreatic cancer and a BRCA1, BRCA2 or PALB2 mutation

Treating Metastatic Pancreatic Cancer Using a New Combination of Chemotherapy Drugs in People with a BRCA1, BRCA2 or PALB2 genetic or tumor mutation (The PLATINUM Trial)

This study will compare a 3-drug chemotherapy combination (NABPLAGEM; gemcitabine, cisplatin, nab-paclitaxel) to a 2-drug chemotherapy combination (gemcitabine/nab-paclitaxel) to treat people with an inherited and/or tumor-associated BRCA1, BRCA2 or PALB2 mutation who have pancreatic cancer that has progressed on front-line treatment with FOLFIRINOX/NALIRIFOX (fluorouracil, irinotecan, leucovorin and oxaliplatin). 

Clinicaltrials.gov identifier: NCT06115499
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VIRTUAL

Surveys, Registries, Interviews
Online survey on stomach cancer risk for people with an inherited mutation in genes that are linked to an increased risk of certain cancers

Understanding Risk Factors for Stomach Cancer in People with Inherited Mutations

The purpose of this study is to understand gastric (stomach) cancer risk among people with an inherited (germline) mutation in genes that are linked to an increased risk of certain cancers, including APC, ATM, BRCA1, BRCA2, CDH1, CHEK2, PALB2, Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM), MUTYH, STK11, and other genes linked to increased cancer risk. 

More info    ›
VIRTUAL

Surveys, Registries, Interviews
Survey for people diagnosed with ovarian cancer

Understanding the Emotional and Social Experiences of Individuals Diagnosed with Ovarian Cancer

A survey for people diagnosed with ovarian cancer to share your experiences, social support, and self-compassion following your diagnosis. 

More info    ›

Prevention
Study focusing on improving outcomes for ovarian and other cancer survivors

CHANCES: Studying the Connection Between Chemotherapy Exposure and Secondary Cancers of the Blood in Ovarian and other Cancer Survivors

The primary goal of the study is to identify risk factors for developing secondary blood cancers and to understand how chemotherapy and PARP inhibitor exposure influence clonal changes in the blood that may predispose to later development of a blood cancer.

Clinicaltrials.gov identifier: NCT06295965
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Treatment
Treatment study for metastatic prostate cancer

Treating Metastatic Prostate Cancer with a New PARP Inhibitor AZD5305 in Combination With Hormone Therapy (PETRANHA)

This study will look at the effectiveness of a new PARP inhibitor drug called AZD5305 in combination with different hormone therapies to treat metastatic prostate cancer, compared to the current standard treatment.

Clinicaltrials.gov identifier: NCT05367440
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VIRTUAL

Surveys, Registries, Interviews
Research study enrolling individuals assigned male at birth (AMAB) who are a confirmed carrier of a BRCA1 and/or BRCA2 mutation

Cancer Risk Perception and Management of Individuals With a BRCA1 or BRCA2 Mutation Who Were Assigned Male at Birth (AMAB)

This study seeks to explore the experiences of individuals with BRCA1 or BRCA2 mutations who were assigned male at birth. We aim to understand your journey to genetic testing and how you perceive and manage your cancer risks.

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Quality of Life
How well cognitive training helps breast cancer survivors with their memory and thinking problems

Cognitive Training for Breast Cancer Survivors with Memory and Thinking Problems

This study will explore how well cognitive training helps breast cancer survivors with their memory and thinking problems caused by cancer.

Clinicaltrials.gov identifier: NCT05896189
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Survey and interview for people who are transgender with a predisposition to cancer who are interested in or taking gender-affirming hormones

Cancer Previvorship and Survivorship and Gender-Affirming Hormones in Transgender Individuals

We are recruiting transgender, non-binary, and gender expansive people to join a research study. We want to learn how to better provide cancer prevention and gender affirming care. If you are at risk for cancer, we want to hear about your experiences talking to your doctor about gender-affirming hormones and cancer risk.

More info    ›
Additional Results on Clinicaltrials.gov
1000 results
Clinical Trial Official Title
NCT05870748 REFRaME-O1: A Study to Investigate the Efficacy and Safety of Luveltamab Tazevibulin Versus Investigator's Choice (IC) Chemotherapy in Women With Ovarian Cancer (Including Fallopian Tube or Primary Peritoneal Cancers) Expressing FOLR1
NCT05766748 Study of Effect of Azeliragon in Patients Refractory to Prior Treatment of Metastatic Pancreatic Cancer
NCT06249048 Phase 1/2 Study of Intratumoral Injection of STX-001 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab
NCT03351348 Bupivacaine vs Placebo for Unilateral Mastectomy Surgical Site Post-operative Pain Control
NCT06336148 A Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid Tumors
NCT04616248 In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors
NCT04678648 A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies
NCT06650579 REVELUTION-2: Relugolix+Abiraterone Acetate (AA) Versus Leuprolide+AA Cardiac Trial
NCT06629779 A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
NCT04792684 Collection of Samples USOPTIVAL Study
NCT03011684 Fertility Preservation Using Tamoxifen and Letrozole in Estrogen Sensitive Tumors Trial
NCT03054584 Genetic Basis of Melanocytic Nevi
NCT06321484 Intraperitoneal Cytokine-Induced Memory Like (CIML) Natural Killer (NK) Cells in Recurrent Ovarian Cancer
NCT04420702 Diffusion Basis Spectrum Imaging of the Prostate
NCT04933084 Pre-operative Education Modalities to Decrease Opioid Use
NCT06831084 Acute Radiation Dermatitis After Adjuvant Radiotherapy for Breast Cancer Patients With the Use of Silver-Plated Technology
NCT05935384 SIBYL: obServation of Therapy Response With lIquid BiopsY evaLuation
NCT03998202 Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer
NCT06691984 Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With Progressive Metastatic Castration-Resistant Prostate Cancer
NCT05870579 [177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer
NCT04080284 Trial of Maintenance With Niraparib- Uterine Serous Carcinoma
NCT05923684 NLP-Based Feedback to Improve Risk Comms and Informed Shared Decision Making
NCT04762979 Alpelisib (BYL719) in Combination With Continued Endocrine Therapy Following Progression on Endocrine Therapy in Hormone Receptor Positive, HER2 Negative, PIK3CA Mutant Metastatic Breast Cancer
NCT06136884 A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors
NCT06599502 A Phase I/IIa Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AZD0022 as Monotherapy and in Combination With Anti-cancer Agents in Adult Participants With Tumours Harbouring a KRASG12D Mutation
NCT06336902 Botensilimab Plus Balstilimab and Fasting Mimicking Diet Plus Vitamin C for Patients with KRAS-Mutant Metastatic Colorectal Cancer
NCT05170802 Pancreatic Cancer & Surgical Resection
NCT07020221 A Phase 1/2a Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
NCT00923221 Collection of Blood From Patients With Prostate Cancer
NCT04038502 Carboplatin or Olaparib for BRcA Deficient Prostate Cancer
NCT06661902 Buffered Lidocaine for Reducing Pain in Patients Undergoing Prostate Biopsy, BURN Trial
NCT06833502 Phase II Study of Systemic Screening in Pathologic Node Positive Breast Cancer
NCT06353321 Non-significant Risk (NSR) Study of [68Ga]-PSMA-11 (Illuccix) as a BgRT BioGuide on RefleXion X1
NCT06706921 18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy in Patients With Prostate Cancer
NCT05984602 A Phase IB Study to Determine the Safety and Tolerability of Canakinumab and Tislelizumab in Combination With Nab-Paclitaxel and Gemcitabine in the Neo-adjuvant Treatment of Patients With Pancreatic Cancer
NCT04990921 Study of Palliative Radiation Combined with Pembrolizumab in Unresectable Metastatic Stage IV Breast Cancer
NCT06535802 iCCaRE Consortium Pilot Project 1: Feasibility of a Point of Prostate Cancer Diagnosis Intervention for Newly Diagnosed Black Men
NCT05677802 Feasibility Study of Biobehavioral Stress Reduction Intervention in Patients With Triple Negative Breast Cancer
NCT06631521 Neoadjuvant Darolutamide and Relugolix Combination Preceding Radical Prostatectomy for Prostate Cancer
NCT05413421 Study of ORIC-944 in Patients with Metastatic Prostate Cancer
NCT06401421 EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)
NCT05685602 CA-4948 Added to Standard Chemotherapy to Treat Metastatic or Unresectable Pancreatic Cancer
NCT06323421 Targeting Chronic Stress for Reducing Risk Factors for Colorectal Cancer
NCT06428721 The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Population
NCT04469764 Abemaciclib for the Treatment of Recurrent Ovarian or Endometrial Cancer
NCT04698564 Utility of Hyperpolarized 13C-pyruvate Metabolic Magnetic Resonance Imaging
NCT04019964 Nivolumab in Biochemically Recurrent dMMR Prostate Cancer
NCT06238921 Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases
NCT06036121 A Study of ADRX-0706 in Select Advanced Solid Tumors
NCT06943521 A Study of MT-4561 in Patients With Various Advanced Solid Tumors
NCT05743621 Study of TVB-2640 in Men With Metastatic Castration-Resistant Prostate Cancer
NCT06150664 A Phase 1 of CTX-8371 in Patients With Advanced Malignancies
NCT04521764 A Vaccine (MV-s-NAP) for the Treatment of Patients with Invasive Metastatic Breast Cancer
NCT05919264 FOG-001 in Locally Advanced or Metastatic Solid Tumors
NCT06327490 A Study Evaluating the Feasibility and Compliance of Manual Lymphatic Drainage Comparing Indocyanine-Green (ICG) Guided vs. Traditional Guided in Patients Undergoing Axillary Node Dissection for the Treatment of Breast Cancer
NCT05949021 OCTANE: Adjuvant Liposomal Doxorubicin and Carboplatin for Early-stage Triple-negative Breast Cancer
NCT05950464 Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer
NCT06824064 Evaluation of RBS2418 in Patients with Advanced, Metastatic, and Progressive Colorectal Cancer
NCT05647564 PET/CT Characterization of Treatment Resistance
NCT04968964 Treatment Monitoring of Patients Receiving CDK 4/6 Inhibitors for Hormone Receptor (HR) Positive, HER2 Negative Metastatic Breast Cancer (MBC) With or Without the Addition of DiviTum® Serum Thymidine Kinase 1 (TK1) Activity Testing
NCT05650021 Rectal Spacer for Prostate Cancer Radiation Image Guidance
NCT02621021 A Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab
NCT04759664 LUT014 for the Reduction of Dose-Limiting Acneiform Lesions Associated With EGFRI Treatment of mCRC
NCT06102902 Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer
NCT02594202 Care of the Prostate Cancer Patient and Prospective Procurement of Prostate Cancer Tissue
NCT04897321 B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)
NCT06873802 ZTE MRI Pulse Sequence Use for Visualization of Bone Cement, Breast Biopsy Markers
NCT04821284 Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer
NCT06580002 Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
NCT04139902 Neoadjuvant PD-1 Inhibitor Dostarlimab (TSR-042) Vs. Combination of Tim-3 Inhibitor Cobolimab (TSR-022) and PD-1 Inhibitor Dostarlimab (TSR-042) in Melanoma
NCT06105684 Phase II Single Arm Trial of Low Dose Capecitabine in Patients With Advanced Breast Cancer
NCT05926102 The Prostate Cancer, Genetic Risk, and Equitable Screening Study (ProGRESS)
NCT04857502 99mTc-PSMA-I&S Biodistribution in Patients With Prostate Cancer
NCT05527184 First in Human Study of IMGN151 in Recurrent Gynaecological Cancers
NCT04368702 CONFIRM: Magnetic Resonance Guided Radiation Therapy
NCT05134779 De-convoluting Interactions Between Genes, the Cancer Environment, and the Immune System to Develop Therapies That Work for You
NCT06237179 Behavioral Exercise Training to Reduce Cardiovascular Disease Risk
NCT05755984 3D Printed Breast Models in the Surgical Management of Breast Cancer
NCT05398302 Image-Guided Biopsies to Identify Mechanisms of Resistance in Patients With Metastatic Castration Resistant Prostate Cancer Treated With 177Lu-PSMA Radioligand Therapy
NCT05780684 Individualized Dose Escalation of 5-FU for Gastrointestinal Cancer
NCT06888102 A Platform Study of Epigenetic Therapy Before Prostatectomy in Men With Prostate Cancer
NCT05741164 Propranolol and Pembrolizumab for Tumor Re-sensitization and Treatment of Patients With Checkpoint Inhibitor Refractory Metastatic or Unresectable Triple Negative Breast Cancer
NCT03833921 Evaluation of Response to Abiraterone/Prednisone by Race/Ethnicity and Other Factors in Metastatic Hormone Naive Prostate Cancer
NCT05296421 Investigating Targetable Metabolic Pathways Sustaining Pancreatic Cancer
NCT05689021 CJNJ-67652000 and Prednisone for Treatment of Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations
NCT05378464 Adoptive T Cell Therapy Following HER2-Pulsed Dendritic Cell Vaccine & Pepinemab /Trastuzumab in Patients w/ Metastatic HER2+ Breast Cancer
NCT06888921 A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer
NCT04373564 Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
NCT06105021 Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor
NCT05786664 Breast Cancer Survivorship Biorepository
NCT05423964 Impact of AI on Trainee ADR
NCT06330064 A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)
NCT05683964 Androgen Receptor Signaling and Prostate-Specific Membrane Antigen Expression
NCT06144164 A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer
NCT05559164 Statins for Reduction of Cardiac Toxicity in Patients Receiving HER2 Targeted
NCT06434064 Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast Cancer
NCT06112379 A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer
NCT05524584 Anastrazole, Fulvestrant & Abemaciclib for HR+HER2- Metastatic Breast Cancer
NCT06750484 Trial of Trastuzumab Deruxtecan in Previously Treated HER2
NCT05419479 Switch Maintenance in Pancreatic
NCT05675579 A Phase II Study of Neoadjuvant Sacituzumab Govitecan and Pembrolizumab Therapy for Immunochemotherapy-resistant Early-stage Triple-negative Breast Cancer (TNBC)
NCT03941379 A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma
NCT05633979 Phase 1b Study of EZH1/2 Inhibitor Valemetostat in Combination With Trastuzumab Deruxtecan in Subjects With HER2 Low/Ultra-low/Null Metastatic Breast Cancer
NCT04820179 Atezolizumab + Cabozantinib in Patients w/ Metastatic, Refractory Pancreatic Cancer
NCT05559879 Cabozantinib and Dostarlimab in Recurrent Gynecologic Carcinosarcoma
NCT06238479 A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors
NCT04753879 Multi-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cancer.
NCT04986579 Scalp Cooling in MBC
NCT06047379 Safety and Efficacy of NEO212 in Patients with Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
NCT06783179 Postoperative Outcomes and Patient Satisfaction With Mayo Clinic Florida Care Hotel After Mastectomy and Tissue Expander Placement
NCT02945579 Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy
NCT06439979 Rural Adult and Youth Sun Protection Study
NCT06728579 Enhanced Pain Coping in Cancer (EPIC): A Study of Managing Treatment-Related Joint Pain in Breast Cancer Survivors
NCT05050084 Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial
NCT05598879 Global Cardio Oncology Registry
NCT06127979 A Study of Changes in Ki67 Expression in People With Breast Cancer Receiving Endocrine Therapy Before Surgery
NCT04683679 A Study of Radiation Therapy With Pembrolizumab and Olaparib or Other Radiosensitizers in Women Who Have Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancer
NCT05507879 TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer
NCT06108479 Study of DF6215 in Patients with Advanced Solid Tumors
NCT01042379 I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
NCT06917079 BBO-11818 in Adult Subjects With KRAS Mutant Cancer
NCT04766190 DISCO: A Patient Intervention to Reduce the Financial Burden of Cancer
NCT06272864 BostonGene and Exigent Genomic INsight Study
NCT04913064 Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast Cancer
NCT04363164 Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression
NCT06284590 Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination with Pembrolizumab, in Unresectable Melanoma Patients
NCT05200364 A Study of STRO-002, an Anti-Folate Receptor Alpha Antibody Drug Conjugate, in Combination With Bevacizumab in Epithelial Ovarian Cancer
NCT05126290 CTNNA1 Familial Expansion Study
NCT04354064 Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors
NCT05826964 Levels of Circulating Tumor DNA as a Predictive Marker for Early Switch in Treatment for Patients With Metastatic (Stage IV) Breast Cancer
NCT06518564 Avelumab and M1774 in ARID1A-mutated Endometrial Cancer (Prior IO)
NCT06666790 DermaSensor Postmarket Surveillance Study
NCT06270043 Focal Therapy for Localized Prostate Cancer
NCT04863443 Nonlinear Elasticity Mapping of Breast Masses
NCT05972343 COOL-IT-PRO: Cryoablation of Breast Cancer in Non-surgical Patients
NCT06864338 Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test
NCT06476808 A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.
NCT01607008 MRI for Assessing Prostate Cancer Response
NCT06831838 A Randomized Controlled Trial (RCT) to Determine the Efficacy of a Multidisciplinary CBT Based Pain Management Program for the Treatment of Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS) in Breast Cancer Survivors
NCT06216938 RP1 in Primary Melanoma to Reduce the Risk of Sentinel Lymph Node Metastasis
NCT05239338 Preserving Fertility After Colorectal Cancer Study
NCT04396808 Genomics in Michigan to AdJust Outcomes in Prostate canceR (G-MAJOR) for Men With Newly Diagnosed Favorable Risk Prostate Cancer
NCT05616650 Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor
NCT06049355 EMBRACE: Exercising Together
NCT04585750 The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
NCT06682650 Implementation of a ColoRectal Cancer Screening Tool in US Primary Care Practices - Usual Quality Improvement (10 Clinics) vs Normalization Process Theory-Participatory Learning in Action (10 Clinics)
NCT06422455 Access to Genetic Testing in Underserved Patients With Cancer
NCT03424850 Safety and Efficacy of 21 Gy, 23 Gy and 25 Gy for High Dose Rate (HDR) Prostate Brachytherapy
NCT06400550 Identification of Metabolic Phenotypes Associated With Melanoma Metastasis
NCT06961955 5 vs. 9-day Course of Whole Breast Radiotherapy With Boost for Early-stage Breast Cancer
NCT05530655 A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer
NCT05301114 Social Risk Factors and Discrimination in Cancer Survivorship
NCT05676255 The Breast Cancer Survivors and Partners Online Research Together (SUPORT) Project
NCT05715255 Adaptive Symptom Self-Management Immunotherapy Study
NCT06617455 Fezolinetant for the Improvement of Vasomotor Symptoms in Breast Cancer Patients Taking Endocrine Therapy, VENT Trial
NCT04729114 A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer
NCT06411795 Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy
NCT05780814 The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer
NCT06733350 Testosterone Replacement Therapy for the Treatment of Low Testosterone in Hypogonadal Men With Localized Prostate Cancer on Active Surveillance
NCT05568550 Pembro With Radiation With or Without Olaparib
NCT04291755 Development and Analysis of a Stool Bank for Cancer Patients
NCT06461650 Preoperative Nicotine Cessation for Women With Breast Cancer Recommended for Reconstruction
NCT06058650 Molecular Breast Imaging Guidance for Breast Biopsy for Patients With Breast Abnormalities
NCT06512350 Identifying Patterns in the Breath of Individuals With Breast Cancer
NCT05086250 Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer
NCT05974150 Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring
NCT05413850 Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection
NCT06151223 A Prospective Registry for Patients at High-Risk for Pancreatic Cancer
NCT05447923 Addressing Disparities in Colorectal Cancer Screening in Black and Underserved Phoenix Communities
NCT03449238 Pembrolizumab And Stereotactic Radiosurgery (Srs) Of Selected Brain Metastases In Breast Cancer Patients
NCT04929223 A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
NCT06636123 GZ17-6.02 in Advanced CRPC After Progression on Anti-Androgen Therapy
NCT06234423 A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors
NCT04348123 Interventional Program Educates, Identifies + Overcomes Barriers to Complete Screening Mammography
NCT05483023 18-fluorofuranylnorprogesterone (FFNP) PET/MRI as a Potential Biomarker of Response to Progesterone Therapy
NCT05373823 MySmartSkin Online Skin Self-exam Intervention for Melanoma Survivors
NCT05779423 Cryoablation+Ipilimumab+Nivolumab in Melanoma
NCT04986423 ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer
NCT06616155 Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer
NCT05286814 PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma
NCT06051695 A Study to Evaluate the Safety and Efficacy of A2B694, a Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
NCT06130995 Relugolix + Enzalutamide Study in High-Risk Prostate Cancer
NCT05014295 Patient Recall of Cancer Screening and Diagnosis
NCT05069038 Clinical Trial Assessing the Safety of Neoadjuvant Palbociclib in Combination With Endocrine Therapy
NCT05030038 Oral Aromatase Inhibitors Modify the Gut Microbiome
NCT06153238 A PK Study to Compare GME751 (Proposed Pembrolizumab Biosimilar) and US-licensed and EU-authorized Keytruda® in Participants With Stage II and III Melanoma
NCT04541108 Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies
NCT05919108 Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers
NCT06016738 OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer
NCT05720338 Is Intraperitoneal Drainage Necessary Following Distal Pancreatectomy?
NCT06006923 Regorafenib in Combination With Pembrolizumab or Pembrolizumab for MSI-H Colorectal Cancer
NCT02313623 MR-US Image Fusion Targeted Biopsy for Single-cell Prostate Cancer Research
NCT06617923 Study of Senaparib in Combination With Temozolomide in ARID1A Mutation Associated Ovarian Cancer
NCT05732623 Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer
NCT06085664 A Pilot Presurgical Trial of REGN5678 (Anti-PSMA x CD28) in Patients With High-risk, Localized Prostate Cancer Followed by Radical Prostatectomy
NCT06257264 A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors
NCT06263543 Sequencing Antibody Drug Conjugates in ER+/HER2 LOW MBC
NCT04705038 Effect of Education on Treatment Decision Making for Patients With Prostate Cancer on Chronic Hormone Treatments
NCT04472338 Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study
NCT06103864 A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer
NCT04965064 Trial of Neratinib Plus Capecitabine in Subjects with HER2-Negative Metastatic Breast Cancer with Brain Metastases and Abnormally Active HER2 Signaling
NCT05471414 Whole-Food Plant-Based Diet to Control Weight and MetaboInflammation in Overweight/Obese Men With Prostate Cancer
NCT04839614 Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia
NCT06112314 IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)
NCT04624555 The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors
NCT04049214 Perioperative Mindfulness Proposal
NCT06659614 Prostate Tissue BioBank
NCT05939414 An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
NCT04003038 Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery
NCT05827614 Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), in Subjects With Tumors With Oncogene Amplifications
NCT06562543 A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer
NCT01794403 Radiation Hypofractionation Via Extended Versus Accelerated Therapy (HEAT) for Prostate Cancer
NCT05663203 A Web-Based Dyadic Intervention for Colorectal Cancer
NCT02393703 Interrogation of Exosome-mediated Intercellular Signaling in Patients With Pancreatic Cancer
NCT06200103 Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer
NCT03842943 Neoadjuvant Combination Immunotherapy for Stage III Melanoma
NCT06349590 Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Prevent Colorectal Cancer Recurrence and Metastasis Following Surgery
NCT06187103 Evaluation of Improved Onboard Patient Imaging
NCT04907643 Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes
NCT06956690 A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of ENV-501 in Patients With HER3-Expressing Solid Tumors
NCT05381103 PSMA-PET to Guide Prostatectomy
NCT05005403 Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer (NSCLC), Head and Neck Squamous Cell Carcinoma (HNSCC) and Other Solid Tumors, Receiving Intravenous (IV) Infusion of Azirkitug (ABBV-514) Alone or in Combination With Budigalimab or Bevacizumab
NCT06738303 Cabazitaxel +/- Carboplatin vs 177Lu-PSMA-617 in Metastatic Castrate-resistant Prostate Cancer
NCT06528990 Telehealth Intervention for Ostomy Self-Management
NCT06218303 Prototype DAA/TAA Vaccine Targeting MUC1 for Immune Interception and Prevention in Ductal Carcinoma In Situ
NCT04005690 Targeted Pathway Inhibition in Patients With Pancreatic Cancer
NCT06112990 Creatine Supplementation and Resistance Training to Preserve Muscle Mass and Attenuate Cancer Progression
NCT05429203 Comparison of Duodenoscope With Single-use Distal Cover and the Conventional Reusable Duodenoscope
NCT06523803 A Study of ZW171 in Participants With Advanced or Metastatic Mesothelin-expressing Cancers
NCT06470243 Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body
NCT06007690 A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma
NCT04658303 Evolution of Metabolic and Immune Dysfunction in In-transit Melanoma
NCT05518903 Investigational Scan (68Ga-FAPI-46 PET/CT) for Imaging of Cancer-Associated Fibroblasts for Localized Pancreatic Ductal Adenocarcinoma
NCT05911243 Feasibility of Auricular Acupressure for Appetite and Weight in Patients With Stage II-IV Gastric, Esophageal, and Pancreatic Cancer
NCT05682443 ONC-392 Plus Lutetium Lu 177 Vipivotide Tetraxetan in Patients With mCRPC
NCT05826743 Safety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the Ileostomy
NCT05968690 Naltrexone and Propranolol Combined With Immunotherapy
NCT05700903 Contributions to Hypertension With Androgen Deprivation Therapy
NCT02775643 Molecular Analysis of Childhood and Adolescent Melanocytic Lesions
NCT03456843 Therapeutic Effect of Cytoreductive Radical Prostatectomy in Men With Newly Diagnosed Metastatic Prostate Cancer
NCT06677190 Belzutifan in Recurrent Clear Cell Ovarian Carcinoma
NCT06441890 BRE-10: Biomarker Optimization of Neoadjuvant Therapy in Breast Cancer
NCT05128890 Evaluation of Resection Techniques for Pancreatic Tumors
NCT06705803 Prostate Ablation Registry and Database for Information, Surveillance, and Evaluation (PARADISE)
NCT06409390 Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer
NCT06067503 Biomarkers to Detect Endocrine Therapy Resistance
NCT05223803 TERPS Trial for De Novo Oligometastic Prostate Cancer
NCT06397703 ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer
NCT05505643 Cryoablation vs Lumpectomy in T1 Breast Cancers
NCT05369546 Lesion Composition and Quantitative Imaging Analysis on Breast Cancer Diagnosis
NCT05049746 Identifying Decision Making Needs for Older Adult Women with Stage I-III Breast Cancer Considering Neoadjuvant or Adjuvant Chemotherapy
NCT02735746 Novel Lung Imaging in Adults Undergoing Radiation Therapy to Assess for Radiation Pneumonitis
NCT06746012 Designing a Dyad-Based MHealth Intervention to Improve Adherence to Lifestyle Recommendations in Colorectal Cancer Survivors and Their Family Caregivers
NCT05058846 Pilot Study of Pancreatic Cancer Screening
NCT06787612 Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer
NCT06099769 A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer
NCT01365169 Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"
NCT06818812 A Study to Evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
NCT01035112 Magnetic Resonance Imaging of Breast Cancer
NCT05245812 Safety and Feasibility of Robotic SP Nipple Sparing Mastectomy
NCT04031469 A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
NCT06677112 MCC-24-GYN-11: Comparison of Nodal Sampling in Endometrial Cancer
NCT05839912 Excision of Lymph Node Trial (EXCILYNT) (Mel69)
NCT05629546 Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint Inhibitors
NCT05654246 Susan G. Komen's ShareForCures
NCT06340646 Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)
NCT06171269 Using MRI to Identify Areas to Receive Lower Doses of Radiation Treatment in Men With Prostate Cancerdose Mapping to Preserve Quality of Life
NCT01102569 Pancreatic Cancer Genetics
NCT06378346 GU-01: Glycyrrhizin in Prostate Cancer
NCT06518746 Gonadal Dysgenesis Tissue Cryopreservation for Fertility Preservation
NCT06698146 Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection
NCT06215469 Portable Scalp Cooling System (PSCS) to Prevent Hair Loss for Breast Cancer Patients (Cooler Heads)
NCT05155046 18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy
NCT05755269 Adding a Genetic Risk Evaluation to Standard Breast Cancer Risk Assessment for African American and Hispanic Women
NCT03821246 Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy
NCT05080946 Using Aspirin to Improve Immunological Features of Ovarian Tumors
NCT06325046 Adaptive Radiation Therapy (ART) Stereotactic Ablative Body Radiotherapy (SABR) for Primary Localized Prostate Cancer
NCT05396846 My Best GI Eating Study
NCT04989946 Androgen Deprivation, With or Without pTVG-AR, and With or Without T-Cell Checkpoint Blockade, in Patients With Newly Diagnosed, High-Risk Prostate Cancer
NCT06678269 A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer
NCT05318469 Ivermectin and Balstilimab for the Treatment of Metastatic Triple Negative Breast Cancer
NCT05113368 Regorafenib Combined With Fulvestrant in Recurrent Low-Grade Serous Ovarian Cancer
NCT04477343 A Study to Evaluate the Safety and Tolerability of SX-682 in Combination With Nivolumab as a Maintenance Therapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma
NCT05396612 Role of the Immune Environment in Response to Therapy in Breast Cancer
NCT06347068 Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells
NCT06027268 Phase II Trial of Trilaciclib, Pembrolizumab, Gemcitabine and Carboplatin in Metastatic Triple-Negative Breast Cancer
NCT04891068 BRE-04: Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast Cancer
NCT02977468 Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancer
NCT03460769 Evaluation of a Mixed Meal Test for Diagnosis and Characterization and Type 3c Diabetes Mellitus Secondary to Pancreatic Cancer and Chronic Pancreatitis (DETECT)
NCT06865768 An Investigational Scan (18F-rhPSMA-7.3 PET-mpMRI) for Targeted Prostate Biopsy Using TRUS-MR Fusion Technique
NCT06228768 Acupressure for Aromatase Inhibitor-Associated Musculoskeletal Symptoms in Patients With Breast Cancer
NCT04606446 Study of PF-07248144 in Advanced or Metastatic Solid Tumors
NCT06500169 Golf Recreational Exercise for Enhanced Survivorship in Prostate Cancer Survivors
NCT04611568 War on Melanoma™ Public Health & Education Campaign
NCT06465368 A Study to Learn About the Study Medicine PF-07220060 Together With Letrozole Compared to Letrozole Alone in Women Post Menopause
NCT06067269 Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial
NCT07047872 A 3D-Printed External Breast Prosthesis for the Improvement of Patient-reported Outcomes Among Breast Cancer Patients That Underwent a Mastectomy Without Reconstruction
NCT05534646 Study of Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer
NCT06444269 Precision Medicine in Action: Phase II Trial of Response Adaptive Ablative Pre-operative SPBI (RAPS) and Non-operative Sentinel Lymph Node Biopsy in Patients With Early-stage ER+ Breast Cancer: RAPS Trial
NCT05703269 Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy
NCT06817668 Evaluating Tolerability of ePUHRT With Brachytherapy Boost
NCT03611868 A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors
NCT04167969 The Use of Nanoparticles to Guide the Surgical Treatment of Prostate Cancer
NCT04365569 Evaluating the Effectiveness of an Individualized Nutrition and Physical Activity Counseling Program
NCT04687969 Multimodal Machine Learning Characterization of Solid Tumors
NCT06835569 A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
NCT06042569 Dose-Reduced Docetaxel With Cyclophosphamide for the Treatment of Vulnerable Older Women With Stage I-III HER2 Negative Breast Cancer, the DOROTHY Trial
NCT05546268 Study of Oral MRT-2359 in Selected Cancer Patients
NCT06182072 ProAgio in Pancreatic Ductal Adenocarcinoma (PDAC)
NCT06400472 A Study of LY4170156 in Participants With Selected Advanced Solid Tumors
NCT06663072 Study to Test the Combination of Fulvestrant With Lu-DOTATATE for Advanced Pancreatic Neuroendocrine Tumors
NCT05712668 Telemedicine Use in Preoperative Counseling for Endometrial Cancer Survivors
NCT06877572 Weight Loss Management in Endometrial Cancer Survivors
NCT06789172 A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors
NCT02863172 Molecular Basis for Variations in Hereditary Colorectal Cancer Syndromes
NCT05868668 Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic Pain
NCT02526368 Pilot Study of (MR) Imaging with Pyruvate (13C) to Detect High Grade Prostate Cancer
NCT05396872 Patient Decision-making About Precision Oncology in Veterans With Advanced Prostate Cancer
NCT05498272 Study of Neoadjuvant PARP Inhibition Followed by Radical Prostatectomy in Patients With Unfavorable Intermediate-Risk or High-Risk Prostate Cancer With Select HRR Gene Alterations
NCT05366881 cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
NCT06173310 DCE-MRI Guided Neoadjuvant Chemotherapy for Borderline Resectable Pancreatic Cancer
NCT06412510 Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT
NCT05827081 Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
NCT04636710 Refining Local-Regional Therapy for IBC
NCT02170181 Clinical Registry for Oligometastic Disease, Consolidation Therapy, Debulking Prior to Chemotherapy, or Re-Irradiation
NCT06572410 Prospective Analysis of EnVisio Spatial Intelligence for Soft Tissue Localization and Guided Surgical Excision
NCT05603910 Phase 1 Clinical Trial of Lenvatinib, Pembrolizumab and Hypofractionated Pelvic Radiation Therapy for pMMR Recurrent/Unresectable Endometrial Carcinoma
NCT03854110 Trial to Evaluate Safety and Tolerability of GP-2250 in Combination With Gemcitabine
NCT03897881 An Efficacy Study of Adjuvant Treatment With the Personalized Cancer Vaccine mRNA-4157 and Pembrolizumab in Participants With High-Risk Melanoma (KEYNOTE-942)
NCT06026410 KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
NCT04370587 A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
NCT05042687 Comparative Performance of Molecular Breast Imaging (MBI) to Magnetic Resonance Imaging (MRI) of the Breast in Identifying and Excluding Breast Carcinoma in Women at High Risk for Breast Cancer
NCT03165487 Comparison of the Breast Tumor Microenvironment
NCT02817633 A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)
NCT06441487 mPATH-Cloud for Colorectal Cancer Screening
NCT06479187 PSMAtrack-tracking Changes in PSMA-PET During Initial Therapy for Metastatic Hormone-sensitive Prostate Cancer
NCT06168487 Telmisartan in Prostate Cancer
NCT02451982 Platform Study of Neoadjuvant and Adjuvant Immunotherapy for Patients With Resectable Adenocarcinoma of the Pancreas
NCT06926920 A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer
NCT05470920 Genetic Testing Decision Aid
NCT04567420 DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)
NCT06188520 A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors
NCT06437574 Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer
NCT05107674 A Study of NX-1607 in Adults With Advanced Malignancies
NCT06441474 Understanding and Addressing Rejection of Personalized Breast Cancer Risk Information in Women
NCT04339374 Ultrasound and Photoacoustic Imaging for Enhanced Differential Diagnosis of Rectal Cancer
NCT05485974 A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation
NCT06625320 Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)
NCT05585320 A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors
NCT05458674 Tucatinib+Trastuzumab+Eribulin in HER2+ MBC
NCT04471974 ZEN-3694, Enzalutamide, and Pembrolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer
NCT05111574 Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery
NCT06202820 CV CARE: CardioVascular Care in PC Patients
NCT03161431 SX-682 Treatment in Subjects With Metastatic Melanoma Concurrently Treated With Pembrolizumab
NCT06671782 A Study of a Pelvic Floor Muscle Exercise Program Before and After Radical Prostatectomy
NCT05869682 Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy
NCT05825482 Breast Margin Study: Routine Cavity Shave Margins Vs. Selective Margins Using Savi Scout®
NCT03909282 Surgical Excision vs Neoadjuvant Radiotherapy+Delayed Surgical Excision of Ductal Carcinoma
NCT04771520 Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors
NCT06750094 A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
NCT04878094 A Study of Intra-operative Imaging in Women With Ovarian Cancer
NCT05633160 64Cu-SAR-BBN and 67CU SAR-BBN for Identification and Treatment of Gastrin Releasing Peptide Receptor (GRPR)-Expressing Metastatic Castrate Resistant Prostate Cancer in Patients Who Are Ineligible for Therapy With 177Lu-PSMA-617 (COMBAT)
NCT05665660 Developing and Evaluating Culturally Relevant Interventions to Improve Breast Cancer Screening
NCT03861676 Image-guided Focal Brachytherapy Utilizing Combined 18F-DCFPyl PET/CT
NCT06023576 A Study of Blood Pressure Control During Cancer Treatment
NCT04697576 Intralesional Influenza Vaccine for the Treatment of Stage I-IV Melanoma
NCT05477576 Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy
NCT04967976 Breast Mesh Used in Two-staged Breast Reconstruction
NCT06399276 4:3 Intermittent Fasting Intervention in Adults With Breast Cancer and Overweight or Obesity
NCT04701476 TATE and Pembrolizumab (MK3475) in mCRC and NSCLC
NCT04872166 A Study of BTX-A51 in People With Advanced Solid Tumor and Breast Cancer
NCT06425926 Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors
NCT05183126 Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With Cancer
NCT05036226 COAST Therapy in Advanced Solid Tumors and Prostate Cancer
NCT05696626 Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
NCT06275126 Optimizing Surgical Decisions in Young Adults With Breast Cancer
NCT04503265 A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies
NCT05156866 First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer
NCT05868226 PRE-I-SPY Phase I/Ib Oncology Platform Program
NCT04768426 Serial Circulating Tumor DNA (ctDNA) Monitoring During Adjuvant Capecitabine in Early Triple-negative Breast Cancer
NCT06833866 Phase I Trial of 5-Fluorouracil (5FU) -Based Therapy in Combination With Hydroxytyrosol (HT) in Patients With Advanced or Metastatic Colorectal Cancer
NCT04812366 Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer
NCT05268666 A Study of Orally Administered JBI-802, an LSD1/HDAC6 Inhibitor, in Patients With Advanced Solid Tumors
NCT05812027 A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors
NCT06727773 Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer
NCT06524973 Telehealth Self-Management Coaching Sessions to Improve Quality of Life in Pancreatic Cancer Survivors and Their Family Care Givers
NCT06318273 A Study to Assess Adverse Events, and How Intravenously (IV) Infused ABBV-969 Moves Through the Bodies of Adult Participants With Metastatic Castration-Resistant Prostate Cancer
NCT02861573 Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)
NCT06294873 Stool Sample Collection Study
NCT05497531 Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers
NCT05546827 PRISAM: Pre-Operative Radiotherapy and Immunotherapy for Sinonasal and Anorectal Melanoma
NCT02064673 Adjuvant Curcumin to Assess Recurrence Free Survival in Patients Who Have Had a Radical Prostatectomy
NCT05123482 A Phase I/IIa Study of AZD8205 Given Alone or in Combination With Anticancer Drugs, in Participants With Advanced or Metastatic Solid Malignancies
NCT02361320 Computed Tomography in Diagnosing Patients With Pancreatic or Hepatobiliary Cancer
NCT04297020 Brain Health in Breast Cancer Survivors
NCT05563220 Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Patients With Metastatic Breast Cancer
NCT06146920 Use of Serial Plasma NGS as a New Efficacy Metric to Guide Immunotherapy Treatment Discontinuation
NCT06270082 Study of IK-595 in RAS- or RAF-altered Advanced Tumors
NCT03127631 A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients
NCT06545682 Phase Ib Study of AlpeliSib With PEmbroLizumab in Patients With mEtastatic Breast caNcer or melanomA (SELENA)
NCT03866382 Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
NCT03995082 Breast Cancer Patient Engagement With Patient Reported Outcome Measure Survey
NCT05994482 Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study
NCT05797831 Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer
NCT06428682 Role of TXA in Patients Undergoing Breast Free Flap Reconstruction
NCT05653882 A Study Evaluating AB248 Alone or in Combination with Pembrolizumab in Adult Patients with Solid Tumors
NCT07023731 A Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D Mutation
NCT05770531 Circulating Tumor DNA to Guide Changes in Standard of Care Chemotherapy
NCT06990880 A Study of GSK5458514 Administered Alone or In Combination With Other Anti-Cancer Agents in Participants With Prostate Cancer
NCT05143229 Alpelisib And Sacituzumab Govitecan For Treatment Of Breast Cancer
NCT04562129 IL2 With Ipilimumab Followed by Nivolumab in Stage 3 or 4 Melanoma Patients
NCT04134780 Ultrasound Imaging and Spectroscopy as Early Indicators of Locally-Advanced Breast Cancer Response
NCT05077280 A Study of Concurrent Stereotactic Body Radiotherapy With Opdualag in Metastatic Uveal Melanoma
NCT05620329 UNC Pleural Fluid Registry
NCT05544929 A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers
NCT05645380 Neoadjuvant TIL- and Response-Adapted Chemoimmunotherapy for TNBC
NCT06708429 Lynch Syndrome X-Talk of Enteral Mucosa With Immune System
NCT06435429 A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer
NCT06194929 Defactinib and Avutometinib, With or Without Encorafenib, for the Treatment of Patients With Brain Metastases From Cutaneous Melanoma
NCT05965180 Interstitial Assessment of Architectural Heterogeneity in Prostate Cancer Using a Fine Needle Photoacoustic Probe
NCT04258280 Improving Genetic Counseling for BRCA+ Mothers
NCT05933265 Study of LP-184 in Patients With Advanced Solid Tumors
NCT05634720 Hepatic Artery Chemotherapy for Patients With Localized Pancreas Cancer
NCT06100874 A Single-arm Phase II Trial of SAcituzumab Govitecan and Trastuzumab for HER2+ Metastatic Breast Cancer After Trastuzumab dEruxtEcaN (SATEEN)
NCT06488365 In Vivo Liquid Biopsy of Melanoma (Cytophone)
NCT06639074 Folate Receptor Alpha Dendritic Cells (FRαDCs) or Placebo for the Treatment of Patients With Stage III or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer, FAROUT Trial
NCT04449874 A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation
NCT05679674 Stereotactic Body Radiation and Tumor Treating Fields for Locally Advanced Pancreas Cancer
NCT03572374 Talking to Employers and Medical Staff About Breast Cancer Treatment and Your Job
NCT05361174 A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer
NCT03452774 SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
NCT05799274 Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer
NCT06393374 Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
NCT04959474 Pre-operative SABR With and Without Caloric Restriction for Early Stage Breast Cancer
NCT02749474 Maternal Cancer Diagnosis and Treatment During Pregnancy:a Database for Maternal, Fetal, and Neonatal Outcomes
NCT06217874 Collection of Specimens and Clinical Data for Patients With Recurrent or Metastatic Breast Cancer or Male Breast Cancer
NCT05931874 Optimizing a mHealth Physical Activity Intervention With Mindful Awareness Lessons in Breast Cancer Survivors
NCT03538665 The DETECT Study: Discovery and Evaluation of Testing for Endometrial and Ovarian Cancer in Tampons
NCT03090165 Ribociclib and Bicalutamide in AR+ TNBC
NCT06253520 Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer
NCT02918474 Decision Making Tool in Supporting Decision Making in Contralateral Prophylactic Mastectomy in Patients With Newly Diagnosed Breast Cancer
NCT06549465 Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer (CRPC)
NCT05020574 Microbiome and Association With Implant Infections
NCT02207465 A Phase I Dual Dose Escalation Study of Radiation and Nab-Paclitaxel in Patients With Unresectable and Borderline Resectable Pancreatic Cancer
NCT05912231 Ultrahypofractionation and Normal Tissue Toxicity
NCT05746182 Genetic Predisposition Testing Program for Pancreatic Neuroendocrine Neoplasms
NCT05464082 Functional Precision Oncology to Predict, Prevent, and Treat Early Metastatic Recurrence of TNBC
NCT04886531 Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers
NCT04998682 Prospective Evaluation of Targeted Axillary Dissection (TAD)
NCT05803382 Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers
NCT06545331 Study of XB010 in Subjects With Solid Tumors
NCT05669482 Study of Avutometinib (VS-6766) +Defactinib With Gemcitabine and Nab-paclitaxel in Patients With Pancreatic Cancer
NCT05806931 Sequential TAS-OX Alternating With TAS-IRI Plus Bevacizumab for Late-Line Metastatic Colorectal Cancer
NCT04406831 The Role of MicroRNA in the Diagnosis, Prognosis and Response to Treatment in Pancreatic Cancer
NCT06636682 FK-PC101 as Adjuvant Therapy for Men With High-Risk Prostate Cancer
NCT05961982 Evaluation of Endoscopic Ultrasound-Guided Radiofrequency Ablation for the Management of Pancreatic Tumors, ERASE Study
NCT05537740 A First-in-human Study to Learn How Safe the Study Drug BAY3375968, an Anti-CCR8 Antibody, is, When Given Alone or in Combination With Pembrolizumab, How it Affects the Body, How it Moves Into, Through, and Out of the Body, and to Find the Best Dose in Participants With Advanced Solid Tumors
NCT06993844 Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors
NCT06361940 Molecular Analyses to Predict Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients with Hormone Receptor-Positive HER2-negative Breast Cancer
NCT04599140 SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial
NCT05056844 Contrast Enhanced Spectral Mammography for the Evaluation of Pathologic Nipple Discharge
NCT04631744 Cabozantinib in Patients With Metastatic Castrate Resistant Prostate Cancer (mCRPC)
NCT05059444 ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
NCT04703244 Development of Patient Derived Xenografts (PDX) in Patients With Breast Cancer
NCT04731844 Curcumin and Piperine in Patients on Surveillance for Monoclonal Gammopathy, Smoldering Myeloma or Prostate Cancer
NCT05458544 [Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application
NCT05242744 FTT PET/CT in Metastatic Prostate Cancer
NCT03823144 Intravital Microscopy in Human Solid Tumors
NCT03682289 Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors
NCT06267729 Study of AZD0754 in Participants With Metastatic Prostate Cancer
NCT06392789 A Conversational Agent (Cecebot) to Improve Insomnia in Stage I-III Breast Cancer Survivors
NCT06171789 PRO1107 in Patients With Advanced Solid Tumors
NCT06401889 Enhancing Skin Appearance and Quality of Life in Breast Cancer Survivors on Aromatase Inhibitor Therapy
NCT05846789 SOC Chemotherapy +/- Tocilizumab for Triple Negative and ER-low Breast Cancers
NCT02000089 The Cancer of the Pancreas Screening-5 CAPS5)Study
NCT06485089 Effects of Tirzepatide on Blood, Imaging and Breast Tissue Biomarkers
NCT01441089 Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis
NCT06566092 Study of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult Participants
NCT04657068 A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
NCT04739072 Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study
NCT05964504 Improving Survival for Metastatic Lobular Breast Cancer (PLUMB Registry)
NCT06952504 A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
NCT05415072 A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas
NCT02021604 Fluorodopa F 18 in Congenital Hyperinsulinism and Insulinoma
NCT01950572 Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma
NCT06728072 Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer
NCT05691504 Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers
NCT03050268 Familial Investigations of Childhood Cancer Predisposition
NCT04044872 Hyperpolarized Carbon 13-Based Metabolic Imaging to Detect Radiation-Induced Cardiotoxicity
NCT05490472 JAB-2485 Activity in Adult Patients With Advanced Solid Tumors
NCT05892068 A Study of Tucatinib Given Before Surgery to People With HER2+ Cancers That Have Spread to the Brain
NCT02279004 A Prospective Study of Plasma Genotyping as a Noninvasive Biomarker for Genotype-directed Cancer Care
NCT06915168 CIPN Decision Aid for the Improvement of Chemotherapy Decision Making in Patients With Breast Cancer
NCT03270072 The Differential Impact of Proton Beam Irradiation Versus Conventional Radiation on Organs-at-risk in Stage II-III Breast Cancer Patients
NCT04829604 ARX788 in HER2-positive, Metastatic Breast Cancer Subjects (ACE-Breast-03)
NCT05837767 A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue
NCT05554367 Palbociclib and Binimetinib in RAS-Mutant Cancers, A ComboMATCH Treatment Trial
NCT06342440 Early Detection of Advanced Adenomas and Colorectal Cancer
NCT06589440 Phase 2 Study of SR-8541A in Combination With Botensilimab and Balstilimab in Subjects With Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)
NCT03564340 Study of REGN4018 Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers
NCT05023967 Metformin and Nightly Fasting in Women With Early Breast Cancer
NCT06239467 First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer
NCT01834001 Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy
NCT05046301 Contrast-Enhanced Mammography for the Evaluation of Mammographic Microcalcifications
NCT06376604 Fasting Mimicking Diet in Chemotherapy of Gynecologic Malignancies
NCT05795101 TRUDI: TDXD+Durva in HER2+/low IBC
NCT06342401 Early Onset Colorectal Cancer Detection
NCT06545604 Comprehensive Yoga Therapy Based Lifestyle Prehabilitation Program for Women With Ovarian Cancer
NCT02333604 Cancer Experience Registry (CER) for Cancer Patients and Caregivers
NCT06129604 Pilot Window of Opportunity Trial (POET)
NCT05130801 A Study of Multiparametric MRI and pHLIP® ICG in Breast Cancer Imaging During Surgery
NCT04314401 National Cancer Institute "Cancer Moonshot Biobank"
NCT03804944 Converting HR+ Breast Cancer Into an Individualized Vaccine
NCT02701244 A Registry Study of Breast Microseed Treatment
NCT02870244 Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes
NCT05726292 A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer
NCT05864144 A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors
NCT05376592 Assoc. of Genomic Polymorphisms With Cancer Cachexia in Subjects With Panc Adenocarcinoma
NCT04415944 Trial Evaluating Feasibility and Quality of Life of Second Look Laparoscopy With Hyperthermic Intraperitoneal Chemotherapy
NCT06533644 A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer
NCT04787744 Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer
NCT06627244 Study of Tebentafusp and Radioembolization in the Treatment of Metastatic Uveal Melanoma
NCT06295744 Outcomes and Cosmesis With Whole Breast Irradiation and Boost
NCT05578092 A Phase 1/2 Study of MRTX0902 in Solid Tumors With Mutations in the KRAS MAPK Pathway
NCT06481592 A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.
NCT05086692 A Beta-only IL-2 ImmunoTherapY Study
NCT05498792 Study of CBL0137 in Combination With Ipilimumab and Nivolumab Therapy in Melanoma
NCT06538389 High Cannabidiol Plant Extract (BRC-001) to Improve Aromatase Inhibitor-Induced Arthralgia in Women With Breast Cancer
NCT06157892 A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors
NCT06478589 Patient Priorities for Survivorship Care in Older Breast Cancer Survivors
NCT05819892 Phase I Trial Testing the Safety and Tolerability of Chemoradiation Followed by Chemotherapy + Dostarlimab for Stage IIIC, Node Positive, Endometrial Cancer
NCT04994067 Intra-Operative Radiation Registry
NCT05736367 Investigating the Metabolic Pathways in Hormone Receptor Positive/HER2 Negative Breast Cancer
NCT05684367 Exercise to ReGain Stamina and Energy (The EXERGISE Study)
NCT06046040 TmPSMA-02 in mCRPC
NCT06643767 Evaluation of the Bexa Breast Examination
NCT03228667 QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors
NCT03606967 Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer
NCT04674267 Resilience and Equity in Aging, Cancer, and Health (REACH)
NCT06521567 A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer
NCT06388967 Pancreatic Cancer Detection Consortium
NCT06824467 A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
NCT06083844 Phase II Investigation of Pembrolizumab in Combination With Bevacizumab and Oral Cyclophosphamide in Patients With High Grade Ovarian Cancer and Surgically Documented Minimal Residual Disease After Frontline Therapy
NCT02402244 Project: Every Child for Younger Patients With Cancer
NCT05367440 Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer
NCT04879940 Phase II Study to Evaluate the Safety and Efficacy of Prostatic Artery Embolization
NCT04512144 Mindfulness in Endometrial and Cervical Cancer
NCT03671044 A Study to Evaluate the Efficacy and Safety of Nanosomal Docetaxel Lipid Suspension in Triple Negative Breast Cancer Patients
NCT02584244 Feasibility of the LUM Imaging System for Detection of Gastrointestinal Cancers
NCT05355701 A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.
NCT06849544 Phase II Trial to Investigate the Safety and Efficacy of Four Dosing Regimens of OTL78 Injection
NCT02478892 Preliminary Evaluation of Screening for Pancreatic Cancer in Patients with Inherited Genetic Risk
NCT03285412 CDK 4/6 Inhibitor, Ribociclib, With Adjuvant Endocrine Therapy for ER-positive Breast Cancer
NCT05043012 Diagnostic Performance Of Non-Endorectal Coil Multiparametric Magnetic Resonance Imaging Of Prostate With Flexible AIR Coil (DoNEMAC Study)
NCT04291612 Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease
NCT06671912 Testing Low Dose Tamoxifen for Invasive Breast Cancer, the (LoTam) Trial
NCT06070012 Tebentafusp in HLA-A*0201 Positive Previously Untreated Metastatic Uveal Melanoma
NCT04754412 Culturally Based Brief Expressive Writing Intervention for the Improvement of Health in Chinese Immigrant Stage 0-III Breast Cancer Survivors, Writing to Heal Study
NCT06989112 DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
NCT06882746 A Study to Test Different Doses of BI 765049 in People With Advanced Cancer of the Colon, Rectum, Stomach, or Pancreas
NCT06503146 18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection
NCT06651580 Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study
NCT05983380 The Effect of Hand Exercises on Upper Limb Volume, Quality of Life, and Hand Function in Breast Cancer Survivors
NCT04684862 Infusion System for Hepatic Cancer
NCT06574880 STereotActic Body Radiotherapy and 177Lutetium PSMA in Locally Advanced Prostate Cancer
NCT05704062 Quantitative MRI Assessment of Breast Cancer Therapy Response
NCT05705401 Testing Radiation and HER2-targeted Therapy Versus HER2-targeted Therapy Alone for Low-risk HER2-positive Breast Cancer
NCT04589468 Researching the Effect of Exercise on Cancer
NCT02332668 A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)
NCT05112601 Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma
NCT05581004 A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors
NCT06103669 Locally AblatiVe TherApy in OLigO-pRogressive SOlid TUmorS (VALOROUS)
NCT05929768 Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
NCT05334069 Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
NCT05789069 A Study of HFB200603 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors
NCT06844669 HER2HEART-US: Prevention of Cardiotoxicity in Breast Cancer Patients Receiving HER2-directed Therapy
NCT05797168 Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors
NCT06362369 A Study of Oral 7HP349 (Alintegimod) in Combination with Ipilimumab Followed by Nivolumab Monotherapy
NCT05469269 Cleveland African American Prostate Cancer Project
NCT06001268 Support Through Remote Observation and Nutrition Guidance Program (STRONG-PCS)
NCT06696768 Clinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal Cancer
NCT05751668 Finding an Effective Dose of GM1 to Reduce or Prevent Neuropathy (Numbness or Weakness) Due to Treatment With Paclitaxel (Phase II)
NCT06408168 Phase II Study of REPotrectinib With or Without Fulvestrant in Patients With Hormone Receptor-positive Human Epidermal Growth Factor 2-negative Metastatic Invasive LObular Carcinoma Who Received a Prior Endocrine Therapy in Combination With Cyclin-dependent Kinase 4 and 6 Inhibitor (REPLOT Trial)
NCT04644068 Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies
NCT06295965 Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers, CHANCES Study
NCT06297265 Manual Lymphatic Drainage Breast Massage in Breast Cancer Patients After Breast Conserving Surgery
NCT05327465 Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy
NCT06721065 A Study of Language Interpretation Solutions for People With Breast Cancer
NCT06610474 Evaluation of an Online Prostate Cancer Screening Decision Aid
NCT05691465 Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells
NCT06268665 Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy
NCT04329065 Concurrent WOKVAC Vaccination, Chemotherapy, and HER2-Targeted Monoclonal Antibody Therapy Before Surgery for the Treatment of Patients With Breast Cancer
NCT06799065 First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer
NCT04756765 Talazoparib Monotherapy in PALB2 Mutation Associated Advanced Breast Cancer
NCT06904365 Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women
NCT00756665 Prostate Active Surveillance Study
NCT06666192 The Ohio State University (OSU) SCREEN Community Program
NCT04106492 Phase 1/2a Study of SQ3370 in Patients With Advanced Solid Tumors
NCT05535192 TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients
NCT05912244 A Study of IO102/IO103, Nivolumab, and Relatlimab in People With Melanoma
NCT06562192 Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
NCT04282044 Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies
NCT06246968 A Study of Pembrolizumab and Cryoablation in People With Breast Cancer
NCT06771544 Metronomic Cyclophosphamide With Pembrolizumab in Checkpoint Inhibitor Refractory Melanoma
NCT03746431 A Phase 1/2 Study of [225Ac]-FPI-1434 Injection
NCT06593431 Extending Outcomes for Pancreas Cancer Patients With Nominal Oligometastatic Disease (EXPAND): A Randomized Phase III Trial
NCT06402331 FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC)
NCT05611931 Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma
NCT05721976 With Love, Grandma ("Con Cariño, Abuelita") Pilot Study
NCT05269160 Topical Dermaprazole for Radiation Dermatitis in Breast Cancer Patients (TOPAZ)
NCT03876860 An Enhanced Vaginal Dilator to Reduce Radiation-Induced Vaginal Stenosis
NCT04134260 Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer, INNOVATE Trial
NCT05040360 Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors
NCT06595160 Association of Plant-based Diet and Gut Microbiome Signature with Response to Neoadjuvant Therapy in Pancreatic Ductal Adenocarcinoma
NCT06141031 Phase I/IB Trial of Radiotherapy in Combination With TTI-101 in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma
NCT05903131 A Behavioral Intervention to Promote Primary Prevention and Uterine Preservation in Premenopausal Women With Obesity and Endometrial Hyperplasia
NCT05206331 CEM to Reduce Biopsy Rates for Less Than Highly Suspicious Breast Abnormalities: a Prospective Study
NCT04175431 Prostate Specific Membrane Antigen (PSMA) or (FACBC) PET/CT Site-Directed Therapy for Treatment of Prostate Cancer, Flu-BLAST-PC Study
NCT04722692 Delayed Sentinel Lymph Node Biopsy in Ductal Cancer in Situ
NCT03919292 Neratinib + Valproate in Advanced Solid Tumors, w/Expansion Cohort in Ras-Mutated Ca
NCT04609592 Study of PRRT in Metastatic, World Health Organization (WHO) Grade 1 or 2, SSTR Positive, GEP-NET Who Are Candidates for Cytoreductive Surgery
NCT06614192 A Randomized Trial Assessing Adverse Events and Disease Activity When Comparing Intravenously (IV) Infused ABBV-400 to Trifluridine and Tipiracil (LONSURF) Oral Tablets Plus IV Infused Bevacizumab in Adult Participants With c-Met Over-Expressed Refractory Metastatic Colorectal Cancer
NCT06072612 Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
NCT04877912 Accurate, Rapid and Inexpensive MRI Protocol for Breast Cancer Screening
NCT06305312 Community Services Navigation to Advance Health Equity in Breast Cancer Screening
NCT06517212 Tirzepatide Weight Loss for MRD+ Early Breast Cancer
NCT05464810 Letrozole With and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negative Breast Cancer
NCT06585410 Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma
NCT06749210 DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY
NCT05979610 Using Reiki Therapy to Improve Symptoms Associated With Brachytherapy in Patients With Gynecological Malignancies
NCT06524895 Reiki Breast Surgery QOL Project for Women Undergoing Breast Surgery
NCT01851395 Rapid Autopsy and Procurement of Cancer Tissue
NCT06315595 Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion and Non-Contrast MRI
NCT06409195 A Trial to Study the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Seborrheic Keratoses and Non-Melanoma Skin Cancers
NCT06484595 Clinical Trial Navigation to Increase Participation and Diversity in Cancer Clinical Trials
NCT03137095 Effects of Chemotherapy on Cognitive Function in Breast Cancer Patients & Non-Cancer Control Subjects With Optional Sub-Study Research Brain MRI
NCT06392295 PSMA-Directed Para-Aortic Radiation Therapy for Oligorecurrent Prostate Cancer
NCT06635980 Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast Cancer
NCT06121180 Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma
NCT05568680 SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma
NCT06130280 A Study of Single Fraction Stereotactic Body Radiation Therapy (SBRT) Guided by Magnetic Resonance Imaging (MRI) in People With Liver Metastasis From Colorectal Cancer
NCT06413680 A First-In Human (FIH) Trial to Find Out if REGN10597 is Safe and How Well it Works for Adult Participants With Advanced Solid Organ Malignancies
NCT05272462 Oral Minoxidil for the Treatment of Recurrent Platinum Resistant Epithelial Ovarian Cancer
NCT05754580 High-dose Brachytherapy Boost With Stereostatic Body Radiation Therapy to Intermediate or Higher Risk Prostate Cancer
NCT06264180 VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs (IGNYTE-3)
NCT06580743 Efficacy Verification in Early Diagnosis and Management of Lymphedema Through Home Body Water Analyzer
NCT06686043 HPV Vaccine, Imiquimod, and Metformin Combination Trial
NCT06675643 Digital Remote Monitoring of Immune Checkpoint Inhibitor Therapy Induced Toxicity: A Feasibility Study of the Vigilant App (Vigilant-2)
NCT06371768 Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors
NCT05838768 Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.
NCT06568692 A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer
NCT05472792 Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy
NCT01954992 Glufosfamide Versus 5-FU in Second Line Metastatic Pancreatic Cancer
NCT05705492 Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer
NCT05155501 Clinical Trial of Approaches to Prostate Cancer Surgery
NCT06086704 Study of 18F-FFNP Breast PET/MRI
NCT02595957 Genomic Services Research Program
NCT06590857 Trial of 225Ac-DOTATATE (RYZ101) in Subjects with ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.
NCT06399757 A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors
NCT04443348 Pre-op Pembro + Radiation Therapy in Breast Cancer (P-RAD)
NCT05721248 STOP-HER2: Stopping Trastuzumab in HER2+ MBC
NCT05669430 A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies
NCT04606030 LymphBridge: Surgical Evaluation for Breast Cancer-Associated Lymphedema (BioBridge)
NCT06533826 TReatment of ADC-Refractory Breast CancEr With Dato-DXd or T-DXd: TRADE DXd
NCT06542757 Evaluation of Tumor Control Based on Serial Multiparametric MRI and Post-Treatment Biopsies For Patients Treated With Dose Intensification to the Dominant Intra-Prostatic Lesion (DIL) Using Ultra-Hypofractionated, MR-Guided Radiotherapy
NCT04545957 Jump: MR Simulation For Radiation Therapy Master Protocol
NCT06557057 Impact of Aromatase Inhibitor Therapy on Glucose Homeostasis and Diabetes Risk
NCT04346225 Magnetic Resonance Imaging (MRI) With Hyperpolarized Pyruvate (13C) as Diagnostic Tool in Advanced Prostate Cancer
NCT06806930 Predicting Response to Neoadjuvant Endocrine Therapy (Neo-PREDICT)
NCT06805825 A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit
NCT05004025 Single Arm Trial of Tumor-Treating Fields in Combination With Nivolumab and Ipilimumab in Metastatic Uveal Melanoma
NCT05877430 Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer
NCT03678025 Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer
NCT05053230 A Study Evaluating the Integrative Medicine at Home (IM@HOME) Program in People With Cancer
NCT04039230 Study to Evaluate Sacituzumab Govitecan in Combination With Talazoparib in Patients With Metastatic Breast Cancer.
NCT05799248 Role of rhPSMA-7.3 PET/CT Imaging in Men With High-Risk Prostate Cancer Following Conventional Imaging and Associated Changes in Medical Management
NCT06710548 REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors
NCT06605430 Medical Cannabis in Patients With Advanced Pancreatic Cancer
NCT04734730 Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer
NCT05673148 Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study
NCT06056830 Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy
NCT03524430 RNA Disruption Assay (RDA)-Breast Cancer Response Evaluation for Individualized Therapy
NCT06297525 Study of STP938 in Advanced Solid Tumours
NCT06610825 Castrate Resistant Prostate Cancer Enhertu Therapy
NCT05922930 Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells Delivered Intraperitoneally for the Management of Platinum Resistant Ovarian Cancer, Mesonephric-like Adenocarcinoma, and Pancreatic Cancer
NCT05746325 Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast Cancer
NCT06358430 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)
NCT05488548 Dual BET and CBP/p300 Inhibitor in Patients With Targeted Advanced Solid Tumors and Hematological Malignancies
NCT05464030 Anti-CEACAM5 ADC M9140 in Advanced Solid Tumors (PROCEADE-CRC-01)
NCT05461430 Mass Response of Tumor Cells As a Biomarker for Rapid Therapy Guidance (TraveraRTGx)
NCT06654622 Exosome-based Detection of Molecular Residual Disease in Stage II-III Colorectal Cancer
NCT05136196 BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study
NCT06898996 FITting Non-invasive Tests in Lynch Syndrome Surveillance
NCT05930496 Evaluating the Effects of an Exercise Intervention on the Gut Microbiota in Stage II-III Colorectal Cancer Survivors
NCT04130516 Study Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and with Pembrolizumab
NCT05646316 Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer
NCT06461416 A Trial for a Preliminary Estimate of the Effectiveness of a Novel Theoretical Framework
NCT03467516 Adoptive Transfer of Tumor Infiltrating Lymphocytes for Metastatic Uveal Melanoma
NCT04251416 A Study of Sacituzumab Govitecan (IMMU-132) in Endometrial Carcinoma
NCT06326216 Determination of Baseline Levels for Prostate Cancer-Derived Extracellular Vesicles Following Local Treatment of Prostate Cancer
NCT03354416 Profiling of Radiological Factors in Treatment and Outcomes in Prostate Cancer
NCT04975516 Standard of Care Chemotherapy With or Without Stereotactic Body Radiation Therapy for Oligometastatic Pancreatic Cancer
NCT03784924 EDRN Prostate MRI Biomarker Study
NCT05225363 Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian Cancer
NCT04575935 Minimally Invasive Surgery After Neoadjuvant Chemotherapy for the Treatment of Stage IIIC-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer, LANCE Trial
NCT06623396 A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer
NCT06826924 7-Days Water-Only Fasting Trial in Prostate Cancer
NCT04677816 Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients
NCT06113016 Prevention of Frailty With Fisetin and Exercise in Breast Cancer Survivors
NCT05013216 Mutant KRAS -Targeted Long Peptide Vaccine for Patients at High Risk of Developing Pancreatic Cancer
NCT04794816 What Women Want: Real Time Results During Screening Mammography in the Era of Patient-Experience Driven Care
NCT06236139 Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer
NCT06492122 Study With [225Ac]Ac-FL-020 in mCRPC Participants
NCT06398639 Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer
NCT04797039 MRI-Guided Cryoablation for Focal Native Prostate Cancer
NCT04918186 Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian Cancer
NCT05336786 Prostate Cancer Diagnosis by Multiparametric Ultrasound (Wholemount)
NCT06610539 PAS 1ml Magtrace® for Sentinel Lymph Node Biopsy in Breast Cancer Patients
NCT05174286 Community Health Workers United to Reduce Colorectal Cancer and Cardiovascular Disease Among People at Higher Risk
NCT06778863 A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
NCT06059963 A Prospective, Multi-center, Observational Study for Signal-C Test Evaluation
NCT04862663 Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)
NCT05438563 MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Intermediate Grade Prostate Cancer
NCT04789486 Nano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic Cancer
NCT06820463 A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer
NCT04792463 Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome
NCT04706663 Precision-Based Genomics in Prostate Cancer
NCT05226663 A Radiotracer ([18F]FluorThanatrace) by PET/CT for the Imaging of Breast Cancer
NCT06423963 Remote Exercise and Nutritional Prehabilitation for Pancreatic Cancer
NCT06421935 M9466 Alone or in Combination in Advanced Solid Tumors (DDriver 501)
NCT05428735 The DRAGON 2 Trial
NCT05998135 Repurposing Atovaquone for the Treatment of Platinum-Resistant Ovarian Cancer
NCT05610735 Combination Therapy for Recurrent Ovarian Cancer
NCT05840263 Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer
NCT06500858 MBC Physical Activity Study
NCT06132958 Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post Immunotherapy Endometrial Cancer (MK-2870-005)
NCT06014086 Intratumoral PH-762 for Cutaneous Carcinoma
NCT04158635 Gemcitabine, Nab-Paclitaxel, and Bosentan for the Treatment of Unresectable Pancreatic Cancer
NCT04074135 Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors
NCT04751435 Developing New Educational Materials About Genetic Testing for a Diverse Group of Cancer Patients
NCT03526835 A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
NCT06250335 Impact of a Prebiotic Food-enriched Diet (PreFED) in Combination With Ipilimumab/Nivolumab Combination Immune Checkpoint Blockade (ICB) in ICB-refractory Melanoma Patients
NCT03420963 Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors
NCT06797635 Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)
NCT02743858 Lymphedema Surveillance Study
NCT04847063 Individualized Response Assessment to Heated Intraperitoneal Chemotherapy (HIPEC) for the Treatment of Peritoneal Carcinomatosis From Ovarian, Colorectal, Appendiceal, or Peritoneal Mesothelioma Histologies
NCT06100263 Breast Cancer Resiliency Through Exercise Program (B-REP)
NCT06662435 GYNecologic Cancer-Related COGnitive Impairment
NCT02830724 Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers
NCT05497024 Older Men's Decision Making About Active Surveillance for Prostate Cancer - Aim 3: Decision Aid Cognitive and Usability Testing
NCT04568616 Phase II Study of Neoadjuvant ArOMatase Inhibitor Therapy for ER+ Breast Cancer (NAOMI)
NCT04646434 Brain and Pelvic Floor Muscle Activity of Patients Who Had or Are Undergoing Robot-Assisted Radical Prostatectomy
NCT05716516 STUDY02001740;22SCH740: Estradiol For ER+ Advanced Breast Cancer (ESTHER)
NCT05125016 A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With Cemiplimab or REGN5678 for Adult Participants With Advanced Prostate Cancer
NCT06246916 A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
NCT05351424 AVI Didactic Experience for Latinx Patient Treatment Adherence and Non-English Speaker Trial Enrollment Study in Rad Onc
NCT03943316 Laboratory Study of Cancer & Immune Cells in Ascites Fluid of Ovarian Cancer Patients to Test Alternative Therapies
NCT05692024 COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER
NCT06551324 A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).
NCT06312124 A Study of Opportunistic Salpingectomy to Prevent Ovarian Cancer
NCT05786924 A Study of BDTX-4933 in Patients With KRAS, BRAF and Select RAS/MAPK Mutation-Positive Cancers
NCT06691035 Immunologic Targeting of ESR1 Receptor for Hormone Receptor Expressing Metastatic Breast Cancer
NCT06617858 Trial of AMB-05X for Patients With ctDNA(+) Colorectal Cancer After Curative-intent Treatment
NCT05377996 A Study of XMT-1660 in Participants With Solid Tumors
NCT06287463 Study of DCC-3084 in Participants With Advanced Malignancies Driven by the Mitogen-Activated Protein Kinase (MAPK) Pathway
NCT06542835 Community Partnership for Telehealth Solutions to Counter Misinformation and Achieve Equity
NCT04331535 The Genomic Medicine at VA Study
NCT06756035 CT-95 in Advanced Cancers Associated With Mesothelin Expression
NCT04188535 Serial MRI Scans During Radiation Therapy
NCT05524935 Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma
NCT04969835 A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours
NCT04799535 Quantitative Microvasculature Imaging for Breast Cancer Detection and Monitoring
NCT04887935 Neoadjuvant SGLT2 Inhibition in High-Risk Localized Prostate Cancer
NCT05384535 Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort
NCT05455658 STEMVAC in Patients With Early Stage Triple Negative Breast Cancer
NCT05830058 Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma
NCT06698458 Alpha Radiation Emitters Device for the Treatment of Pancreatic Cancer Emitters With Chemotherapy for the Treatment of Locally Advanced and Metastatic Pancreatic Cancer
NCT03686124 ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors
NCT06291324 WATD and Cancer-Related Fatigue: A Study For Patients Undergoing Anti-Cancer Treatment
NCT06925724 A Study of Ivonescimab in People With Endometrial and Cervical Cancers
NCT05268224 A Tear-based, Lab-developed Test for Breast Cancer for Women With Dense Breast Tissue
NCT05776524 Study of Amplitude-Modulated Radiofrequency Electromagnetic Fields in Metastatic Pancreatic Cancer
NCT03965234 Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases
NCT06639724 Perioperative Fostamatinib With Gemcitabine and Nab-paclitaxel in Resectable Pancreatic Cancer
NCT06704724 A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.
NCT06410534 A Phase II Study Evaluating an Organ Preservation Strategy Using Immune Checkpoint Blockade for Participants With Primary Colorectal or Gastroesophageal Cancer
NCT06391034 Magnetic Resonance (MR) Imaging With Hyperpolarized 13C-Pyruvate +/- 13C,15N-Urea in Patients With Prostate Cancer
NCT06298916 64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer
NCT06466434 Prebiotic Food-enriched Diet (PreFED) to Enhance the Microbiome and Response to First-line Immunotherapy in Unresectable Melanoma
NCT05036096 Cone Beam Breast CT for Breast Cancer Screening
NCT06568016 A Clinic-wide Intervention (Primary Care-GI Connect) for Improving Rates of Colonoscopy After Abnormal Fecal Immunochemical Test Result in Patients at Federally Qualified Health Centers
NCT06584396 Evaluating Mechanical Properties of Post-Mastectomy Skin Flaps to Estimate Reconstruction Risks, the EMPOWER Study
NCT04751396 Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
NCT04457596 T-DM1 and Tucatinib Compared with T-DM1 Alone in Preventing Relapses in People with High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial
NCT05548296 A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma
NCT06703996 InBody Band 3 Fitness Tracker to Improve Health Outcomes and Quality of Life in Black Prostate Cancer Survivors
NCT00034216 Collection of Blood From Patients With Cancer
NCT03454035 Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors
NCT04022616 Myeloid-Derived Suppressor Cell Function in Breast Cancer Patients
NCT05838716 High-Dose Vitamin D Supplementation for ADT-Induced Bone Loss in Older Prostate Cancer Patients
NCT06492616 A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
NCT06205316 SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate Adenocarcinoma
NCT06084416 A Study of Sovilnesib in Subjects with Ovarian Cancer
NCT05054296 Modifying Metabolic Syndrome and Cardiovascular Risk for Prostate Cancer Patients on ADT Using a Risk Factor Modification Program and Continuous Fitbit Monitoring
NCT05462496 Modulation of the Gut Microbiome With Pembrolizumab Following Chemotherapy in Resectable Pancreatic Cancer
NCT04997096 Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy
NCT05864196 Two Fraction Prostate SBRT With DIL SIB
NCT06122896 Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals
NCT03990896 Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial
NCT06364696 A Study to Find a Suitable Dose of ASP4396 in Adults With Solid Tumors
NCT03819296 Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer
NCT04318717 Pembrolizumab and Hypofractionated Radiation Therapy for the Treatment of Mucosal Melanoma
NCT06879041 A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer
NCT05803941 Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer
NCT04513717 Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial
NCT06610617 Neuromodulation of Central Sensory Integration to Improve Postural Control
NCT06579417 ART-Pro: Clinical Trial Evaluating Biparametric MRI and Advanced, Quantitative Diffusion MRI for Detection of Prostate Cancer
NCT06486441 Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26)
NCT01042548 Proteomics and Radiomics Research of Breast Cancer Markers in Tissue, Interstitial Fluid and Serum
NCT06307548 Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer
NCT05752448 Survivorship Care for Women Living With Ovarian Cancer: (POSTCARE-O)
NCT03767348 Study of RP1 Monotherapy and RP1 in Combination With Nivolumab
NCT06065748 A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)
NCT06726148 Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and Other Advanced Solid Tumors
NCT04567706 A Storage Facility for Tissues Obtained From Patients With Malignant Melanoma
NCT06059118 Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer
NCT05988918 Multicenter Trial of ESK981 in Patients With Select Solid Tumors
NCT05168618 Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer, The AtezoCab Trial
NCT06827613 A Study of Invikafusp Alfa (STAR0602), a Selective T Cell Receptor (TCR)-Targeting, Bifunctional Antibody-fusion Molecule, in Combination With Sacituzumab Govitecan in Participants With Advanced Solid Tumors
NCT06205836 Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer
NCT01913106 HSV-tk + Valacyclovir Therapy in Combination With Brachytherapy for Recurrent Prostate Cancer
NCT05590949 Observational Study of Bone Complications in People With Post-menopausal Breast Cancer Who Have Stopped Treatment With Denosumab and Aromatase Inhibitors
NCT05341349 Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-100M for the Treatment of Melanoma Brain Metastases
NCT05245006 PET Imaging Study of 89Zr-DFO-YS5 in Men With Prostate Cancer
NCT06855706 An Automated Personalized Physical Activity Intervention to Improve Immune Function and Clinical Outcomes in Stage II-IV Ovarian, Primary Peritoneal or Fallopian Tube Cancer and Newly Diagnosed Endometrial Cancer, Life on the Go 3 Study
NCT04073706 Sentinel Node Biopsy in Endometrial Cancer
NCT04557449 Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
NCT03190941 Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients
NCT04206319 Radium-223 in Biochemically Recurrent Prostate Cancer
NCT06591819 Hypofractionated WPPT With HDR Boost
NCT05624918 A Study of NovoTTF-200T(P) in Combination With Gemcitabine and Nab-Paclitaxel for Resectable Pancreatic Adenocarcinoma
NCT00949819 Active Surveillance for Cancer of the Prostate (ASCaP)
NCT04851119 Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
NCT03805919 Men at High Genetic Risk for Prostate Cancer
NCT06824818 Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients
NCT05636618 Targeted Alpha-Particle Therapy for Advanced SSTR2 Positive Neuroendocrine Tumors
NCT04796818 An Investigational Scan (Intravoxel Incoherent Motion Diffusion Weighted Imaging) for the Evaluation of Colorectal Cancer Liver Metastases Treatment Response
NCT05848141 Rowing Following Breast Cancer Chemotherapy
NCT05627219 Extending Prostate Genetic Awareness, Navigation, and Delivery: The EXPAND Network
NCT04038619 Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients
NCT05271318 Oncolytic Adenovirus Coding for TNFa and IL2 (TILT-123) With Pembrolizumab or Pembrolizumab (Phase 1a and 2) and Pegylated Liposomal Doxorubicin (Phase 1b) as Treatment for Ovarian Cancer.
NCT06599619 Effects of Anti-PD1 Adjuvant Checkpoint Blockade Immunotherapy on Atypical/Dysplastic Nevi
NCT05683418 A Study to Evaluate the Safety and Tolerability of TOS-358 in Adults With Select Solid Tumors
NCT06904313 Ultralow Dose PET Imaging for PSMA Expression
NCT05637216 Losartan to Reduce Radiation Induced Fibrosis in Breast Cancer Patients
NCT06566716 A Diagnostic Test to Evaluate Cancer Risk Before Surgery in Women with an Ovarian Mass
NCT06551116 QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer
NCT05232916 Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
NCT03175224 APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
NCT05349227 Comprehensive Outcomes for After Cancer Health
NCT05034627 Calaspargase Pegol-Mnkl and Cobimetinib for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer
NCT05556473 F-Tryptophan PET/CT in Human Cancers
NCT05914116 A Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
NCT05305924 Fulvestrant+Abemaciclib With Run-In of Fulvestrant in Er-Positive, Her2-Negative Metastatic Breast Cancer
NCT04711824 Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases
NCT03492424 Ablative Therapy in the Management of Prostate Cancer
NCT05981716 Young Breast Cancer Survivors Study
NCT05590624 Metabolic Impact of Prospective Controlled Mediterranean Type Diets on Prostate Cancer
NCT06974734 A Clinical Trial of PF-08046037 Alone or With Sasanlimab in Patients With Advanced or Metastatic Malignancies
NCT05751434 A Study on the Effects of Exercise Therapy on Signs of Prostate Cancer
NCT05415917 Adjuvant Gemcitabine and Capecitabine Chemotherapy in Resected Pancreatic Cancer Following Neoadjuvant Chemotherapy
NCT04548817 Neurocutaneous Melanocytosis Registry
NCT06906341 Relacorilant in Combination With Nab-paclitaxel and Bevacizumab in Advanced, Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer
NCT04981834 Robot-Assisted Radical Prostatectomy With or Without Vesicopexy in Patients With Prostate Cancer
NCT07020117 A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors
NCT06067841 A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer
NCT06736717 Onvansertib in Combination With NALIRIFOX for First Line Treatment of Advanced Pancreatic Cancer
NCT06801236 Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer
NCT06723236 A Study of MGC028 in Participants With Advanced Solid Tumors
NCT06858449 Resistance Training and Post Workout Protein to Improve Body Composition During Neoadjuvant Chemotherapy for Breast Cancer
NCT04890613 Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation
NCT05141513 Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma
NCT04081636 Prostate Biopsy, Transrectal vs. Transperineal: Efficacy and Complications
NCT06355336 Real World Prostate Cancer Registry
NCT06252649 Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
NCT06637306 Neoadjuvant Dupilumab, Pembrolizumab, Paclitaxel, and Carboplatin in Locally Advanced Triple Negative Breast Cancer
NCT02838836 Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers
NCT06153836 Neurotization of the Nipple Areolar Complex to Restore Sensation for Patients With Breast Cancer Undergoing Nipple Sparing Mastectomy and Reconstruction
NCT06205849 Intra-tumoral Mitazalimab (CD40 Antibody) With Irreversible Electroporation (IRE) in Locally Advanced Pancreas Cancer
NCT02600949 Personalized Peptide Vaccine in Treating Patients With Advanced Pancreatic Cancer or Colorectal Cancer
NCT04114136 Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies
NCT04055649 ONC201 Plus Weekly Paclitaxel in Patients With Platinum Refractory or Resistant Ovarian Cancer
NCT04349436 A Phase 1B/2 Study of RP1 in Solid Organ Transplant Patients With Advanced Cutaneous Malignancies
NCT06880549 A Study of mRNA-4106 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Solid Tumors
NCT05754749 Comparison of CE-DBT and MRI in Patients With Known Breast Lesions
NCT05946824 This Study is Evaluating a New Radiation Treatment Technique for Patients Who Have Had Prostate Cancer, Undergone Surgery for Cancer, and Then Have Evidence That Their Prostate Cancer Has Returned.
NCT04858334 APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
NCT04975217 Fecal Microbial Transplants for the Treatment of Pancreatic Cancer
NCT06384417 Using an End-of-life Conversation Game to Engage Patients With Cancer in Advance Care Planning: Phase 2
NCT05514717 A Study of XMT-2056 in Advanced/Recurrent Solid Tumors That Express HER2
NCT06379217 NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.
NCT05997017 Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer
NCT00912717 Pancreatic Adenocarcinoma Gene Environment Risk Study
NCT06298734 High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial
NCT04305834 Abemaciclib and Endocrine Therapy in Older Patients with Breast Cancer.
NCT05170334 Binimetinib Plus Belinostat for Subjects With Metastatic Uveal Melanoma
NCT06757634 Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)
NCT06075524 Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types
NCT06011434 Testing Conversation Aid in Practice
NCT05468034 Exercise in Metastatic Breast Cancer: EMBody
NCT02290834 Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast Cancer
NCT05321134 Evaluation of SINGLE PORT (SP) Robotic Technology in Colorectal Surgery
NCT05565534 Diabetes Care for Breast Cancer Patients
NCT04119024 Gene Modified Immune Cells (IL13Ralpha2 CAR T Cells) After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors
NCT05297734 Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer
NCT05989724 A First-in-Human Study of SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors
NCT06274034 MUSE-S Headband System for Improving Anxiety and Insomnia Among Breast Cancer Survivors
NCT05812924 A Novel Therapy for Breast Cancer Survivors With Genitourinary Syndrome of Menopause
NCT05748834 Study of Tucatinib and Doxil in Participants With Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer
NCT05565417 Study of the Monoclonal Antibody IMT-009 in Patients with Advanced Solid Tumors or Lymphomas
NCT03646617 Ipilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic Melanoma
NCT05787834 Home-based Respiratory Muscle Training for Minimizing Side Effects in Patients Undergoing Treatment for Breast Cancer
NCT05743517 Physical Activity Intervention Among Older Women With Gynecologic Cancers (Fit4Treatment)
NCT06433219 Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302)
NCT04489719 Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer
NCT05804318 Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer
NCT06625034 Radiation Therapy With RapidPlan Knowledge-based Planning vs Human-Driven Planning for Treatment of Prostate Cancer
NCT05356117 Resistance Exercise Combined With Protein Supplementation in People With Pancreatic Cancer: The RE-BUILD Trial
NCT06582017 Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma
NCT04981119 Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
NCT06144619 Non-Invasive Biomarkers in Prostate Cancer Disease Management
NCT04903119 Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma
NCT06887218 5-Fluorouracil/Leucovorin (5FU/LV) in Combination With Regorafenib in Patients With Metastatic Colorectal Cancer
NCT06648434 MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma
NCT05607017 Losartan in Prevention of Radiation-Induced Heart Failure
NCT06395519 A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
NCT05455619 Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer
NCT06388018 Tailoring Therapy in Post-surgical Patients With Low-risk Endometrial Cancer
NCT04997018 A Study of MRI-guided High-dose Radiation Therapy in Prostate Cancer
NCT06111313 The University of Miami Adapt (UAdapt) Trial
NCT07064018 Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies
NCT05790213 Prostate Cancer Treatment Using Androgen Deprivation Therapy and Focal Prostate Ablation
NCT06105918 Radioligand Therapy After PSMA PET Guided External Beam Radiotherapy for Treating Post-Prostatectomy Patients with Biochemically Recurrent Prostate Cancer
NCT05536713 Understanding Patient Preference on Colorectal Cancer Screening Options
NCT05411718 A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome
NCT04222413 Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors
NCT04371913 Personalized Second Chance Breast Conservation (PSCBC): A Prospective Phase II Clinical Study
NCT03096418 Neoadjuvant Weekly Paclitaxel and Biomarkers of Therapy Response
NCT05879913 ASCVD Management Using CCTA in Prostate Cancer Patients on ADT
NCT06060613 Safety and Efficacy of OBX-115 in Advanced Solid Tumors
NCT05035836 A Phase 2 Single-Arm Open-Label Pilot Trial Evaluating Zanidatamab (ZW25) in Patients With Early Stage HER2/Neu Positive (HER2+) Breast Cancer (BC)
NCT04851613 Study Evaluating Efficacy & Safety of Afuresertib Plus Fulvestrant in Patients w/ Locally Advanced or Metastatic HR+/HER2- Breast Cancer
NCT04692818 3D Ultrasound Breast Imaging
NCT06666218 Helping Ovarian Cancer Patients Cope With Their Illness (HOPE)
NCT06800313 A Study of HLD-0915 in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)
NCT06084013 Use of Indocyanine Green in Pancreas Surgery
NCT05056818 Comparison of Synthetic Mammography Versus Full-Field Digital Mammography in Image Interpretation and Performance Metrics
NCT06507618 Pre-Operative Window of ET to Inform RT Decisions (POWER II)
NCT06534918 Precise Oncology Interventions in Nutrition and Training (OnPoint)
NCT06303713 LuCarbo - a Study of 177Lu-PSMA-617 Plus Carboplatin in Metastatic Castrate-resistant Prostate Cancer
NCT06603818 Immunotherapies in Combination With Stereotactic Body Radiation Radiotherapy in Microsatellite Stable (MSS) Metastatic Colorectal Cancer (mCRC)
NCT05946213 Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
NCT06526819 SMP-3124LP in Adults With Advanced Solid Tumors
NCT04599218 MR/TRUS Fusion Guided Prostate Biopsy - An Improved Way to Detect and Quantify Prostate Cancer
NCT05977036 BettER: Biomarker Driven Early Therapeutic Selection in Patients With HR+ HER2- Metastatic or Unresectable Breast Cancer
NCT06064149 The CArdiovascular Risk Evaluation in Men With Prostate Cancer Study (CARE-PC) Pilot Feasibility Study
NCT04270149 Cancer Peptides Plus GM-CSF and Adjuvant in Breast Cancer
NCT04071236 Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive to Hormonal Therapy
NCT06699836 A Phase 2 Study of Leronlimab in Combination With TAS-102 + Bevacizumab in Previously Treated Participants With mCRC
NCT06105749 Biennial CEM in Women with a Personal History of Breast Cancer
NCT05141149 First in Human Phase1/2a Clinical Trial of Anti-PAUF Monoclonal Antibody PBP1510 in Patients With Pancreatic Cancer
NCT05193149 Inspiratory Muscle Training in Obese Breast Cancer Survivors
NCT06994832 Using Visual Arrays to Support Understanding of Genetic Risk
NCT05325632 Study of HER2 Directed Dendritic Cell (DC1) Vaccine + Weekly Paclitaxel, Trastuzumab & Pertuzumab
NCT05820932 Predicting Cognitive Decline From Androgen Deprivation Therapy
NCT06760637 Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease
NCT04683315 PurIST Classification-Guided Adaptive Neoadjuvant Chemotherapy by RNA Expression Profiling of EUS Aspiration Samples
NCT05428007 Interleukin-6 Receptor Inhibitor Sarilumab in Combination With Ipilimumab, Nivolumab and Relatlimab in Patients With Unresectable Stage III or Stage IV Melanoma
NCT05226507 A Phase 1 Clinical Study of NXP800 in Subjects with Advanced Cancers and Expansion in Subjects with Ovarian Cancer
NCT05723107 EUS RFA for Treatment of Pancreatic Ductal Adenocarcinoma (PDAC)
NCT05887609 An Evaluation of Maintenance Therapy Combination Mirvetuximab Soravtansine and Olaparib
NCT06760507 Evaluating an Evidence-Based Family History Screening Program Adapted to Increase Reach and Uptake of Screening for BRCA-Associated Cancers in Rural Public Health Clinics
NCT05123807 Secondary Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Recurrent Mucinous Ovarian Cancer (HI-MOC Study)
NCT05722288 Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers
NCT05095207 Abemaciclib in Combination With Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer
NCT04990609 EUS-RFA PANCARDINAL-1 Trial
NCT06598007 A Study to Determine the Effect of CT3001 in Patients with Advanced Solid Tumors
NCT06464107 Endometrial Cell Collection With the PadKit
NCT06555588 Engage Psychosocial Intervention for Cancer Symptoms
NCT04858009 Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis
NCT05035407 T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and Other KK-LC-1 Positive Epithelial Cancers
NCT03932409 Frontline Immunotherapy Combined With Radiation and Chemotherapy in High Risk Endometrial Cancer
NCT04837209 Radiation, Immunotherapy and PARP Inhibitor in Triple Negative Breast Cancer
NCT04720209 Taking AIM at Breast Cancer
NCT05291507 Feasibility Evaluation of the Muse Magnetic Resonance Guided Focused Ultrasound System
NCT03941756 Lymphovenous Bypass Procedure Before Underarm Lymph Node Surgery in Preventing Lymphedema in Patients With Inflammatory or Locally Advanced Non-inflammatory Breast Cancer or Melanoma
NCT06411756 Physical Activity Centers Empowerment
NCT03740256 Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors
NCT06689956 Outcomes of Low-Risk Endometrial Cancer With Isolated Tumor Cells in the Sentinel Lymph Nodes: A Prospective, Multicenter, Single-Arm Observational Study
NCT06271356 Breast Cancer - Navigate - Prospective Cohort