Search Results: (30 results)

This clinical trial is testing whether using acupressure guided by the EnergyPoints App can reduce cancer-related fatigue and improve sleep in adult cancer survivors residing in the U.S.

This study is testing a new targeted drug called daraxonrasib to see if it helps people with metastatic pancreatic cancer live longer or keep their cancer from growing longer than standard chemotherapy alone. Researchers are comparing daraxonrasib by itself or combined with chemotherapy to standard chemotherapy.

This study is for adults with advanced/metastatic HR-positive, HER2-negative advanced or metastatic breast cancer who have previously been treated with a CDK4/6 inhibitor and have received two or less treatments for their advanced metastatic breast cancer.

Phase 2 study comparing talazoparib with or without Enzalutamide in patients with metastatic castration-resistant prostate cancer and an HRR mutation after progression on Abiraterone Acetate or Darolutamide

This study tests whether COM701 (an anti‑PVRIG immunotherapy) given every 3 weeks as maintenance can delay cancer growth after a good response to platinum chemotherapy. Adults with relapsed platinum‑sensitive ovarian, fallopian tube, or primary peritoneal cancer are randomized 2:1 to COM701 or placebo.

People with Lynch syndrome currently rely on regular colonoscopies to screen for colorectal cancer. Researchers are studying whether a simple stool-based test called the fecal immunochemical test (FIT) can help identify people who may need a colonoscopy while reducing the burden of frequent screening. This study will compare FIT results with colonoscopy findings in people with Lynch syndrome.

This trial will study the safety, tolerability, and initial effectiveness of MOMA-341, a new type of targeted therapy, alone or in combination with a standard chemotherapy (irinotecan) or together with an immunotherapy to treat people with advanced or metastatic cancers with certain types of mutations.

We are conducting a fully-online research study to learn more about how genes affect your risk of breast cancer. No office visit is required. Participants provide consent online, answer questions online about their health and medical history, and provide DNA via a saliva sample using a pre-paid mailer through the mail. In return for participation, study participants may receive information about their genetic ancestry for free.

Study enrolling breast cancer survivors, caregivers, and individuals at high risk for breast cancer. Participants may complete surveys or participate in an interview, depending on availability

Today, researchers are learning about breast cancer from a small subset of patients, who are not representative of all breast cancer patients. ShareForCures® is an online registry that offers people who have been diagnosed with breast cancer a way to participate in research by connecting information about themselves with their breast cancer diagnosis, medical records, genomics. Participation is open to anyone adult, living in the United States, and who has been diagnosed with breast cancer.

The purpose of this study is to understand gastric (stomach) cancer risk among people with an inherited (germline) mutation in genes that are linked to an increased risk of certain cancers, including APC, ATM, BRCA1, BRCA2, CDH1, CHEK2, PALB2, Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM), MUTYH, STK11, and other genes linked to increased cancer risk. 

A diagnosis of cancer or other serious medical condition changes everything — including your mental health. Those experiencing negative mental health changes after receiving a diagnosis may be dealing with what is known as Adjustment Disorder.

The Vanguard Study is looking at how multi-cancer detection (MCD) blood tests could fit into cancer screening.

Researchers are studying certain rare variants in the BRCA1 and BRCA2 genes that may affect cancer risk differently than more common harmful variants in BRCA1 and BRCA2. The goal is to learn more about the cancer risks associated with these specific variants and help improve recommendations for cancer screening and prevention.

This Patient and Caregiver survey was created by volunteers from two non-profit groups to learn more about immunotherapy side effects. No personal information is collected. Goals include sharing results with doctors, care teams, and patient groups; gathering information about better ways to handle immune-related side effects; and working with researchers to find and test better ways to treat immune-related side effects.

This study is collecting feedback on educational materials about breast MRI from Black and Latina women ages 18-74 who are at high risk for breast cancer.

This study is for people with prostate cancer that is considered high risk for recurrence. It compares two radiation therapy schedules to see whether a shorter course of treatment works as well as the standard, longer course at preventing the cancer from coming back or spreading.

Diverse volunteers are invited to participate in this research study about the patient experience in genetic counseling.

This is a Phase III, randomized, global, open-label clinical trial to see if a new drug Daraxorasib (RMC-6236) helps prevent pancreatic cancer from returning after surgery and chemotherapy.

This study will explore how “dear family letters” influence understanding of genetic risk and cascade testing among individuals and families affected by hereditary cancer.

This observational study follows participants over time to better understand the long-term effects of nipple-sparing mastectomy.

Researchers are studying whether a smartphone app can help improve quality of life for Black men with prostate cancer. The app is designed specifically for Black men and includes:

• Information about prostate cancer.
• A way to track symptoms and share concerns with healthcare providers.
• Personal stories from other people with similar experiences.

This study is testing whether taking daraxonrasib, a new oral cancer medicine, after surgery and standard chemotherapy can help people with pancreatic cancer stay cancer-free for longer.

We are conducting a clinical trial to see if our education materials help people at risk for Lynch syndrome decide about seeking genetic services, such as genetic counseling and testing.

Interview with Latino/a parents to share their experiences about their child's genetic care

We want to learn about your experience with genetic testing and the healthcare providers you worked with, such as genetic counselors and oncologists.

This study is testing two different vaccine-based treatment approaches combined with immunotherapy for people with pancreatic cancer that can be removed with surgery

Researchers are conducting a study to better understand how people make important health decisions and how they feel about those decisions over time. The goal of this study is to learn what factors help patients feel confident and satisfied with their health-related decisions, as well as what may lead to regret or uncertainty later on.

The purpose of this study is to understand knowledge and opinions about pancreatic cancer screening, access to and decision-making around screening, and how a blood-based test might influence screening among individuals with inherited (germline) mutations associated with increased pancreatic cancer risk, including APC, ATM, BRCA1, BRCA2, CDKN2A, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, STK11, and TP53. 

Research study on how couples’ experience with cancer-related financial challenges affects their health and relationship.