Risk management for people with inherited RAD51D mutations
The National Comprehensive Cancer Network (NCCN) provides risk management guidelines for people with RAD51D mutations. We recommend that you speak with a genetics expert who can look at your personal and family history of cancer and can help you determine the best risk management plan. You can learn more about risk management options in our section on Screening and Risk Reduction by Cancer Type.
Ovarian cancer prevention
- Consider risk-reducing salpingo-oophorectomy (removal of ovaries and fallopian tubes) between the ages of 45-50 or earlier if there is a family history of an earlier ovarian cancer.
Breast cancer screening and prevention
- There has not been enough research to show a benefit from screening and prevention for breast cancer in women who have a RAD51D mutation. For this reason, experts recommend managing these risks based on personal and family history of cancer.
If you are a person with a RAD51D mutation making decisions about managing your cancer risk, you can find peer support through the following resources:
- Register for the FORCE Message Boards to connect with others who share your situation.
- FORCE's Peer Navigation Program will match you with a volunteer who shares your mutation and situation and provide you with a free resource guide.
- Contact the FORCE impact leaders in your area to link to local support groups and other resources.
- Attend a virtual support meeting in your area.
- Read the stories from members of our community.
The following screening and prevention studies are open to people with a RAD51D mutation.
- NCT03805919: Men at High Genetic Risk for Prostate Cancer. This is a prostate cancer screening study using MRI in high risk men. This study is open to men with mutations in RAD51D and other mutations.