Hereditary Cancer and Genetic Testing

General information for people with inherited RAD51C mutations

Both men and women can carry a mutation in the RAD51C gene.

People with an inherited mutation in RAD51C have an increased risk for certain cancers.  See the Cancer Risk section for more information.  There are guidelines for prevention for certain cancers in people with a RAD51C mutation. There also may be clinical trials available for people who test positive for a RAD51C mutation.  See our Risk Management section for more information about medical recommendations in people with RAD51C mutations. 

People who have a RAD51C mutation who have been diagnosed with cancer may qualify for specific treatment or clinical trials. Visit the Cancer Treatment section for more information about clinical trials for people with a RAD51C mutation.

Inheriting a RAD51C mutation from both parents can cause Fanconi anemia. See our Other Considerations section for more information about this disorder.

The RAD51C gene is located on chromosome 17. RAD51C is involved in DNA repair.


If you are a person with an RAD51C mutation, you can find peer support through the following resources: