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Other considerations for people with MUTYH inherited mutations

Because of the high lifetime risk of cancer with MAP, people with a MUTYH mutation of reproductive age may wish to speak with a genetics expert to discuss carrier screening for their partner, prior to having children. There are options using assisted reproduction technology and preimplantation genetic diagnosis when both parents carry a MUTYH mutation to select embryos that are free of mutations in both copies of their MUTYH. 

Last updated February 13, 2022