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Endometrial Cancer > Risk Management Options

Endometrial Cancer Risk Management

Every woman is at risk for endometrial cancer and the risk increases with age. The average lifetime risk for endometrial cancer is about 3 percent. This means that 1 out of every 33 women will get endometrial cancer in her lifetime. Note that when we use "women" we are referring to the sex assigned at birth.

An inherited mutation in one of the genes listed below increases the risk for endometrial cancer, often at a younger age.

Genes with Endometrial Cancer Risk-Management Guidelines

Genetic counseling and testing can help you learn if you have an inherited mutation in one of these genes. There are different expert guidelines for endometrial cancer risk management, which are based on your level of risk. Read below for more information about different risk-management options. Speak with your healthcare provider to decide on a risk-management plan and schedule that is right for you. 

In the News

Hair straightening products linked to small increased risk of endometrial cancer

Study: Hair straightening products linked to small increased risk of endometrial cancer

Many people use products to straighten their hair. Use of these products, especially frequent use, is linked to a small increase in endometrial cancer.  (Posted 4/18/23) Este artículo está disponible en español.

Risk-Management Options

Screening

Screening for endometrial cancer uses tests to try to catch cancer in its early stages. In high-risk people, regular screening for endometrial cancer may not improve cancer outcomes. High-risk people should discuss the benefits and limitations of endometrial screening with their doctor.

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Medications to Reduce Risk

Medications may lower the risk for endometrial cancer in people with inherited mutations. More research is needed to help experts understand how well these medications work, and which patients will benefit most from their use. 

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Surgery to Reduce Risk

Hysterectomy is surgery to remove the uterus. People with a very high risk for endometrial cancer, may choose to have hysterectomy to lower their risk. Read more about the guidelines and surgery options.

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More Resources

Last updated February 13, 2024