FORCE Blog | PALB2

Hereditary Cancer and Genetic Testing

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Hereditary Cancer

Learn about gene changes called mutations, how inherited mutations can lead to cancer, what types of cancer may be hereditary and how parents can pass gene mutations to their children.

What is Genetic Testing?

Explore information about genetic testing for an inherited mutation, the benefits and limitations of genetic testing and the type of results you might receive.

How to Get Genetic Testing

Review expert guidelines regarding who should consider genetic testing, how to find a genetics expert and how to move forward with testing.

Hereditary Cancer Genes and Risk

Read about different genes that are linked to hereditary cancer and the risks associated with inherited mutations in these genes.

After Testing, Now What?

Learn how to make medical decisions and assemble your health care team once you receive your genetic test results.

Sharing with Family

Discover steps that will help you prepare to communicate your family medical history or genetic test results with relatives.

Risk Management and Treatment

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Screening and Risk Reduction

Review national guidelines for cancer screening and prevention; this information is listed by gene mutation and by cancer type.

Cancer Treatment

Read about cancer treatment options listed by gene mutation, type of cancer and type of treatment.

Reconstruction or Going Flat

Understand options for having breast reconstruction or not after mastectomy.

Menopause

Learn about symptoms and options for managing early menopause caused by cancer treatment or preventive surgery.

Wellbeing and Survivorship

Discover how cancer treatment and prevention affects long-term health, quality of life and emotional well-being; explore options for addressing these issues.

Fertility and Family Planning

Understand the effects of cancer treatment and prevention on fertility and family planning, how pregnancy impacts hereditary cancer risk and options for assisted reproduction.

Research and Clinical Trials

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Why Enroll in Research?

Learn why you should consider enrolling in a research study and your rights and protections as a research participant.

How to Find Studies

These tips and resources will help you locate clinical trials and studies enrolling people like you.

Search and Enroll

Ready to enroll? Our tools will help match you to hereditary cancer detection, prevention and treatment studies.

Help Shape Research

FORCE trains patients who are new to science to use their personal experiences to help guide hereditary cancer research.

Research Collaborations

Learn about ongoing studies, and the role that FORCE, our research advocates, and our partners have played in shaping the research.

Privacy, Policy and Legal Issues

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Laws and Protections

Learn about key laws and legal protections that impact people with, or at increased risk of, hereditary cancer; and, how to file a grievance or complaint.

Public Policy Priorities

See what legislative and regulatory policy issues FORCE is actively engaged in, representing the unique needs of people and families affected by hereditary cancer.

Advocacy Archive

Read about the public policy initiatives that FORCE undertook in the past, ensuring that the voice of the hereditary cancer community was heard.

Support

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Personalized Guidance

Get matched with a Peer Navigator volunteer who shares a similar experience as you for confidential 1:1 phone/email support and receive a free expert-reviewed resource guide.

Local Support

FORCE has volunteers throughout the United States and in Essex, United Kingdom who are available to offer support and share resources.

Support Meetings and Events

Attend support meetings or learn from experts at webinars and conferences. You can ask questions, share your story or just listen.

Message Boards

Our message boards are available 24/7 and are the easiest way to reach out to others who are facing hereditary cancer.

Helpline

Peer volunteers return calls within 48 hours and provide nonjudgmental support and resources in English and Spanish. A Genetic Counselor helpline is also available.

Find Healthcare Providers

Locate medical experts who are knowledgeable in cancer genetics.

Insurance and Paying for Care

Find information on insurance coverage and financial assistance for genetic services, risk management and cancer treatment.

Volunteer

FORCE has opportunities for people of our community to get involved in significant ways to raise awareness, provide support or help promote research of hereditary cancer.

Education

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Behind the Headlines (XRAY)

Our XRAY program takes you behind the headlines to bring you reliable information about cancer research-related news and information.

Webinars

Our live and on demand webinars feature presentations by experts on topics of interest and importance to our community.

Blog

Our blogs feature personal perspectives and deep dives into topics of interest to the hereditary cancer community.

Brochures

Order or download our educational materials.

Glossary

Find definitions for commonly used terms.

Our blog features educational information and personal perspectives relevant to the hereditary cancer community.

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Books And Movies (12)

Breast Reconstruction And Going Flat (10)

Cancer Treatment (8)

Decision Making (2)

Emotional Health And Well Being (3)

FORCE And FORCE Impact (28)

Fertility And Parenting (1)

Genetic Testing (14)

Health Equity And Disparities (8)

Health And Fitness (4)

Hereditary Cancer - General (9)

Inspirational (27)

Laws, Protections And Public Policy (27)

Men With Mutations (9)

Quality Of Life (1)

Risk Management (5)

Supporting FORCE (5)

Volunteer Spotlight (50)

The Importance of Talking About Family Medical History: The Discussion That Led to My ATM and PALB2 Diagnosis

August 24, 2020

The Importance of Talking About Family Medical History: The Discussion That Led to My ATM and PALB2 Diagnosis

Posted in: Stories
Tags: Breast Cancer, PALB2, ATM, Colorectal Cancer, Family Story, Family Tree

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A PALB2 Gene has Taken a Terrible Toll on my Family

August 01, 2020

A PALB2 Gene has Taken a Terrible Toll on my Family

Posted in: Stories
Tags: Hereditary Cancer, Breast Cancer, Genetic Testing, Previvor, PALB2

Breast Cancer and Then a PALB2 Mutation Inherited From My Father

August 24, 2020

Breast Cancer and Then a PALB2 Mutation Inherited From My Father

Posted in: Stories
Tags: Breast Cancer, PALB2, Men With Mutations

Updates to the Practice Guidelines for Hereditary Cancer

November 09, 2018

Updates to the Practice Guidelines for Hereditary Cancer

Posted in: Guidelines
Tags: BRCA, Breast Cancer, Genetic Testing, Prostate Cancer, PALB2, ATM, Lynch Syndrome, Men With Mutations, NCCN, FANCA

I Am a Two-Time Survivor of Breast Cancer Caused by a PALB2 Mutation

August 24, 2020

I Am a Two-Time Survivor of Breast Cancer Caused by a PALB2 Mutation

Posted in: Stories
Tags: Breast Cancer, PALB2, Breast Cancer Survivors, Breast Cancer Treatment

Flawed Research and Reporting on the “Angelina Effect” Could Threaten Access to HBOC Care

January 26, 2017

Flawed Research and Reporting on the “Angelina Effect” Could Threaten Access to HBOC Care

Posted in: Laws, Protections And Public Policy , XRAY
Tags: BRCA, Hereditary Cancer, Breast Cancer, Hereditary Cancer Research, Prophylactic Mastectomy, BRCA2, Previvor, Gene Testing, HBOC, PALB2, CHEK2, ATM

100th XRAYS: 5 Lessons We Have Learned

August 22, 2017

100th XRAYS: 5 Lessons We Have Learned

Posted in: XRAY
Tags: BRCA, Hereditary Cancer, Breast Cancer, Young Survivor, HBOC, PALB2, ATM, Health Journalism, Breast Cancer Risk, Young Onset Breast Cancer

No Longer Alone: 1000 People Benefit from Personalized Cancer Risk Support

October 23, 2017

No Longer Alone: 1000 People Benefit from Personalized Cancer Risk Support

Posted in: FORCE And FORCE Impact
Tags: BRCA, Hereditary Cancer, Breast Cancer, Cancer Prevention, Hereditary Cancer Research, Ovarian Cancer, Genetic Testing, Previvor, Survivor, HBOC, Prostate Cancer, Screening And Prevention, PALB2, PTEN, CHEK2, ATM, RAD50

We All Love a Good Book or Movie

October 09, 2019

We All Love a Good Book or Movie

Posted in: Inspirational , Books And Movies
Tags: BRCA, Breast Cancer, Ovarian Cancer, Genetic Testing, BRCA1, BRCA2, Prophylactic Surgery, HBOC, Reconstruction, PALB2, PTEN, CHEK2, ATM, Mastectomy

PARP Inhibitors and Hereditary Cancer: What’s New?

April 12, 2018

PARP Inhibitors and Hereditary Cancer: What’s New?

Posted in: Research , Cancer Treatment
Tags: BRCA, Ovarian Cancer, Genetic Testing, BRCA1, BRCA2, PALB2, Pancreatic Cancer, ATM, Gene Panel Testing, Metastatic Breast Cancer, Ovarian Cancer Treatment, PARP Inhibitor, Cancer Research, Advanced Breast Cancer, Inherited Mutations, Prostate Cancer Treatment, Metastatic Prostate Cancer, Cancer Targeted Therapy

Where's FORCE? March and April

May 30, 2018

Where's FORCE? March and April

Posted in: Laws, Protections And Public Policy , FORCE And FORCE Impact
Tags: BRCA, Hereditary Cancer, Breast Cancer, Hereditary Cancer Research, Ovarian Cancer, Genetic Testing, Survivor, HBOC, PALB2, Cancer Advocacy, Pancreatic Cancer, ATM

Solving for Y: Reaching Men About Genetic Testing for Hereditary Breast, Ovarian, Pancreatic, Prostate And Related Cancers (HBOC)

June 17, 2018

Solving for Y: Reaching Men About Genetic Testing for Hereditary Breast, Ovarian, Pancreatic, Prostate And Related Cancers (HBOC)

Posted in: Men With Mutations , Genetic Testing
Tags: BRCA, Hereditary Cancer, Breast Cancer, Cancer Prevention, Genetic Counseling, BRCA1, BRCA2, Previvor, Gene Testing, HBOC, Prostate Cancer, USPSTF, Screening And Prevention, PALB2, PTEN, Pancreatic Cancer, Male Breast Cancer, CHEK2, ATM

New Year’s Then (20 Years Ago) and Now

December 31, 2018

New Year’s Then (20 Years Ago) and Now

Posted in: FORCE And FORCE Impact
Tags: BRCA, Hereditary Cancer, Genetic Testing, Previvor, PALB2, Cancer Advocacy, ATM, Cancer Risk, Ovarian Cancer Advocacy

FORCE and Other Groups Meet with the Centers for Medicare and Medicaid Services (CMS)

February 22, 2019

FORCE and Other Groups Meet with the Centers for Medicare and Medicaid Services (CMS)

Posted in: Laws, Protections And Public Policy
Tags: BRCA, Hereditary Cancer, Hereditary Cancer Research, Screening And Prevention, PALB2, ATM

I am a PALB2 Previvor

May 22, 2020

I am a PALB2 Previvor

Posted in: Stories
Tags: Hereditary Cancer, Genetic Testing, PALB2

Luck Is More Than Just A Rainbow: A PALB2 Previvor's Story

August 24, 2020

Luck Is More Than Just A Rainbow: A PALB2 Previvor's Story

Posted in: Stories
Tags: Previvor, PALB2

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