Categories Prevention, Screening



Relevance: Medium
Most relevant for: Healthy people at high-risk of ovarian cancer.
Study: Frequent aspirin use may reduce the risk of ovarian cancer
Aspirin may help lower the risk of ovarian cancer in people who have a high risk of the disease, according to a new analysis of 17 studies. While other preventive strategies have been found to more effectively lower the likelihood of developing ovarian cancer in high-risk women, taking aspirin daily or almost daily may reduce a person’s risk of developing ovarian cancer by 13 percent. The benefit was greater among people with additional risk factors for the disease. (Posted 2/22/23)
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Relevance: Medium
Most relevant for: People with a BRCA1 or PALB2 mutation undergoing prophylactic bilateral mastectomy
Update: Breast cancer vaccine trial begins enrolling people with BRCA1 and PALB2 mutations
A new vaccine was first tested on people diagnosed with triple-negative breast cancer. The vaccine is now being tested to prevent breast cancer among people with an inherited mutation in BRCA1 or PALB2 who are at high risk and who are planning to have a risk-reducing mastectomy. (Posted 1/9/23) Este artículo está disponible en español.
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Relevance: High
Most relevant for: Americans Indians and Alaska Natives
Topic: Cancer disparities in American Indian and Alaska Native populations
The American Cancer Society released a special section in their 2022 Cancer Facts & Figures report that discussed cancer disparities in American Indian and Alaska Native populations in the United States. This review highlights the special section’s main points, including disparities in cancer screening, diagnosis and survival rates in native communities, as well as factors contributing to those disparities. (Posted 12/20/22)
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Relevance: Medium-High
Most relevant for: People with early-stage colorectal cancer
Study: Liquid biopsies personalize early-stage colon cancer treatment
Liquid biopsies look for DNA or other products from cancer cells in the blood or other body fluids. These tests may be used to help find cancer recurrence early, monitor response to treatment or guide treatment selection for people diagnosed with cancer. This study looked at a type of liquid biopsy called “circulating tumor” (ctDNA) to identify people with early-stage colon cancer who can safely skip chemotherapy after surgery. (Posted 11/22/22) Este artículo está disponible en español.
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Relevance: High
Most relevant for: People with Lynch syndrome
Study: Prostate cancer screening may benefit people with Lynch syndrome
Initial results from the IMPACT trial show that PSA testing to screen for prostate cancer in people with Lynch syndrome can detect aggressive early prostate cancers. These findings support the use of PSA screening in men with Lynch syndrome, particularly men with an inherited mutation in an MSH2 or MSH6 gene. (Posted 11/10/22)
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Relevance: Medium-High
Most relevant for: People with Lynch syndrome and people with a personal and/or family history that suggests Lynch syndrome
Study: Resistant starch may help prevent some cancers in people with Lynch syndrome
This study looked at whether a type of nutrient known as resistant starch could lower the risk of cancers in people with Lynch Syndrome. Researchers found that resistant starch can reduce the risk of non-colorectal cancers but not colorectal cancer. (Posted 10/17/22)
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Relevance: High
Most relevant for: People at increased risk for pancreatic cancer because of family history or an inherited mutation.
Study: Screening for pancreatic cancer detects early-stage disease and improves survival
A research study has shown that screening for pancreatic cancer in people with an inherited mutation or family history was able to detect early-stage pancreatic cancers and improve survival. These results will likely change pancreatic cancer screening guidelines for high-risk individuals (Posted 8/30/22)
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Relevance: Medium-High
Most relevant for: People with an inherited BRCA mutation
Study: Risk-reducing ovarian cancer surgery and quality of life
People with an inherited BRCA gene mutation are recommended to have surgery to remove their ovaries before the age of natural menopause to reduce their risk of ovarian cancer. This surgery can cause short-term and long-term effects. This study assesses the quality of life among people who have their fallopian tubes surgically removed and later have their ovaries removed compared to people who have their ovaries and fallopian tubes removed at the same time. (Posted 7/26/22). Este artículo está disponible en español.
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Relevance: Medium-High
Most relevant for: People who are concerned about their own or their loved one’s risk of prostate cancer
Study: Metastatic prostate cancer cases increased as screening use declined
The number of people diagnosed with metastatic prostate cancer increased following a change in recommendations around the use of routine prostate cancer screening. (posted 6/13/22)
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Relevance: Medium-High
Most relevant for: Transgender men with an inherited mutation
Article: Breast cancer risk for transgender men with inherited mutations
There is little information related to the risks and treatment options for transgender men and nonbinary people who are at high-risk for breast cancer due to an inherited BRCA1 or BRCA2 mutation. We review an expert viewpoint on the implications of a BRCA mutation for transgender men undergoing breast removal as part of their gender-affirming care plan. (posted 5/19/22)
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